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Author Topic: Can high doses of vitamin d cause peyronies?  (Read 973 times)

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keeblerellf

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Can high doses of vitamin d cause peyronies?
« on: December 30, 2021, 11:34:52 AM »
I was watching some youtube videos promoting high doses of vitamin d (10,000iu/day and even higher for some conditions). I noticed someone in the youtube comments mention that they developed peyronies after taking high dose vitamin D, although they didn't say how much or for how long. I was taking those type doses for several years before my peyronies developed pretty rapidly. I know Dr Coimbra and others have had 1000s of patients on very high dose (100,000iu/day) for years for specific medical issues and have never heard this reported. Nevertheless, tissue calcification sounds similar to peyronies and excess vitamin d can cause that although it appears very rare. I have taken vitamin K2 to prevent this for years but it still is concerning. Anyone?
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keeblerellf

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Re: Can high doses of vitamin d cause peyronies?
« Reply #1 on: December 30, 2021, 11:49:53 AM »
I found a study that concludes there is a direct link:

Is high levels of vitamin D a new risk factor for Peyronie's disease?
https://pubmed.ncbi.nlm.nih.gov/31482615/
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Hawk

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Re: Can high doses of vitamin d cause peyronies?
« Reply #2 on: December 30, 2021, 12:32:43 PM »
People riding bikes, taking Vit D, having Vit D deficiency, Masturbating, not masturbating, smoking, not smoking, all get Peyronies Disease.  I got it after I started learning to play the guitar.

My point is humans search for cause and effect.  Without extensive well-engineered studies to show cause, we look for anything to hang cause on.  A guy taking vitamin D then getting Peyronies Disease is about as useful as a guy who said he started to drink eight glasses of water a day and developed Peyronies Disease within three weeks.

There is zero evidence even suggesting that Vitamin D at any dose causes Peyronies Disease.
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Prostatectomy 2004, radiation 2009, currently 70 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
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keeblerellf

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Re: Can high doses of vitamin d cause peyronies?
« Reply #3 on: December 30, 2021, 05:09:04 PM »
I literally just posted a published study finding a link between high vitamin D and peyronies.
Vitamin D isn't water, it's a hormone that increases calcium uptake.
Calcification is a signature of Peyronie's plaques.
This isn't even remotely controversial.
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Anbil

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Re: Can high doses of vitamin d cause peyronies?
« Reply #4 on: January 05, 2022, 12:57:56 PM »
32.6 ± 7.9 ng/ml vs. 18.5 ± 6.6 ng/ml respectively. p < 0.001).

Depending on your reference range, neither of these are high and may even qualify as deficient.

It's a very interesting idea but the numbers from this study do not imply a "high" dose whatsoever. Excess vitamin D would be around 50 ng/ml levels which neither group is remotely close to.
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Onset of pain in March 2021
Progressed to loss of girth to dent under the glans left side

Been doing daily heat,traction,pentox,ved,cialis since initial onset of pain

Currently still experiencing pain and dent unchanged

BrettC

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Re: Can high doses of vitamin d cause peyronies?
« Reply #5 on: April 22, 2022, 10:07:06 AM »
It's an abstract and one study... in the same database there are two studies one saying low testosterone puts you more at risk and then another saying it is not a factor. 

I would say... it could be.  Definitely something someone is looking at.  But I don't think we have any definitive answers of anything that causes Peyronie's.  It remains a mystery... I think we all suspect certain factors and contributing things.  And it may be smart to avoid super high doses of any vitamin really... they all seem to be beneficial in the right doses and harmful at super high ones. 
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51 years old
Diagnosed 4 years ago with an upward curve of 60-65 degrees.
Completed one full round of treatments with Xiaflex (8 injections)  Measured curve 40-45 degrees after that
Using Restorex and took oral medications as well (Pentox Cials)

Christopher1

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Re: Can high doses of vitamin d cause peyronies?
« Reply #6 on: July 03, 2022, 02:14:32 PM »
Vitamin K2 (MK-4) decalcifies the tissues.
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I also used Todd Capistrant's "Fascial Distortion Model" to help my curvature. Start slowly.

thegreycat

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Re: Can high doses of vitamin d cause peyronies?
« Reply #7 on: August 09, 2022, 07:23:16 AM »
I've been taking 500IU Vit D daily since March 2020 - because of the immune system against covid.

I've started to wonder if this sustained high dose, plus a multivit which has vit D, plus getting lots of sun exposure as I do, has had an effect.

I've stopped Vit D as of yesterday, and I've got high dose K2 on the way, for what good it might do.
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35. No injury. Lump Feb 22.
Still waiting on Urologist referral.
Large dent, left hand & upward hinge 50deg. Bad erections.
Supportive partner but severe depression.
Vit E 1000mg, VED Oct 22. Cialis 5mg Dec 22. Only worsening since.

jj21

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Re: Can high doses of vitamin d cause peyronies?
« Reply #8 on: August 12, 2022, 05:43:33 AM »
Does it have to be MK4? Or is MK7 sufficient?
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33 yrs old
Peyronies for 4 years now
Got better but then got worse
Mild erect curvature but major Loss of girth, dents and significant semi-erect curve
Moderate Erectile Dysfunction
Re-started VED, also using Restorex

thegreycat

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Re: Can high doses of vitamin d cause peyronies?
« Reply #9 on: August 12, 2022, 09:43:45 AM »
Quote from: jj21 on August 12, 2022, 05:43:33 AM
Does it have to be MK4? Or is MK7 sufficient?

I've got MK7 - as far as I can tell it's just where it's derived from, doesn't have any kind of different effect. I may be wrong.
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35. No injury. Lump Feb 22.
Still waiting on Urologist referral.
Large dent, left hand & upward hinge 50deg. Bad erections.
Supportive partner but severe depression.
Vit E 1000mg, VED Oct 22. Cialis 5mg Dec 22. Only worsening since.

CrookedDanger

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Re: Can high doses of vitamin d cause peyronies?
« Reply #10 on: August 16, 2022, 12:06:44 AM »
Oh crap I also take a vitamin D pill everyday (125mcg or 5k IU) and also take 2 multivitamins as well. After reading this I think I should stop it, so I might just do that.
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90 degree twist,45 degree angle to the right at the base from prone masturbation
Circumference bruise on 7/19/22 from light manual traction while erect caused flaccidhourglass
PAC,coq10,ATC, pelvicfloortherapy
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