Extremely Positive Results from Verapamil

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ek

I've been suffering from Peyronies Disease for about 18 months.  I have hourglass Peyronies Disease in 3 distinct spots: around the base like tournaquet, a small spot about halfway up, and a large scar (at least pencil eraser sized) in the head.    The base is the most problematic, as it caused unbelievable blockage and rendered me effectively impotent.   The other two clearly reduce my size and alter the shape, but the pain associated with them is the worst.

My doctor took a methodical / conservative route, first putting me on Pentox for about 3 months.  The improvements were so small, they were barely noticeable and could have been mother nature.  He then added daily Testim gel to the mix, which helped with the impotence but didn't do anything for the actual Peyronies Disease.   I could get erections for a couple minutes, but the pain associated with pushing the blood around the scars was bad. So bad that I didn't have much of an interest in having sex, even though I was now able to.

After 6 months of that combination, my doctor finally started me on Verapamil injections.  I recall saying to my Doctor before the first injection, "we're running out of bullets, aren't we".  He said Yes, I wasn't a good candidate for surgery, so if this didn't work I was looking at a potential lifetime of semi-impotence.    I was completely pessimistic about Verapamil because all I ever read were neutral to negative reviews.   However, I was amazed by what happened...He shot the whole first dose into my tournaquet-like scar and by the next day it was relaxing.  I thought it might have been temporary but it wasn't.  I was quickly about 40% better.  I got my 2nd injection a couple weeks later, again all into the scar at the base.  That relaxed it another 40%.     That's all I've gotten so far, but I'm going back for round 3 next week and will ask for it in the middle spot.  I'm already at a point where I can live happily, and am just so thankful for Verapamil.

Anyway, I just wanted to share that for guys that were as despondent as I was...there is hope with Verapamil!  

Worried Guy

That is great news!  Everyone is different and I'm glad something is working for you.  In the UK I don't know of any Uro who carries out this option.  There are other people on here who it has helped also.  

LWillisjr

ek,
Thanks. That is good news. We have hear of very limited success with VI's. So itis good to know this is working for you.
Developed peyronies 2007 - 70 degree dorsal curve
Traction/MEDs/Injections/Surgery 2008 16 years Peyronies free now
My History

restore

That is great news! My local uro said that might be what I should try after I become stable.  But I drive the two hours to the specialist I'm seeing, and he seems to think Xiaflex will be our best hope.  I'm going to ask him about verapamil for me.  

mike67

EK
Good positive results. I have had it for 9 months. My URO(S) have me on Pentox , Cialis , L'Arginine and I am a pumping fool, halfway through my second 26 week stretch(pardon). I am self administering Ubiquinol. No improvement yet.
My next visit is in 4 weeks. I think he is going to start me on Verapamil. If not the first Uro , then my other appointment in June. He gave me the Rx for Pentox.
He mentioned in December that he has has good results with the injections. Last visit he indicated injections were a strong possibility. I want to get fixed like all the others . But somehow I think I would rather go somewhere to get my throat cut than allow someone to stick needles in my penis. Can you describe what happens and how much pain/discomfort you went through with the injections? I imagine they give you an erection then stick you? I have a 45 degree bend about 1 inch( during erection) from the base. I have no pain during erections. As in the old movies , perhaps a shot of Brandy would help .
Thanks for anything you can relate .
Mikey

LWillisjr

mike67,
I would assume many do it the same way, but as Levine was my doc I can only say for certain how he does them. His nurse would always come in first to inject the numbing medicine. This involves two sticks (don't you love their medical terms). One on each side at the base of the penis. This was more in the pelvis than on the penis itself. But still is very close to right at the base, one on each side. And while this wasn't a direct injection in my penis, these two sticks are not pleasent. Be prepared, take a deep breath. It takes about 10 minutes or so for the medicine to take full effect, and by this time you should be totally numb in your penis.

Levine would come in about this time and would do the actual VI. They do not give you an erection as it isn't necessary. The doc should know right where your plaque is at.

The other thing I did after my first VI was to take an ice pack with me. I would lay this between my legs for the drive home, but I had a 3 hour drive. I also took it easy and didn't do much the rest of the day. The following morning I would be fine, no pain, etc. But my penis was shades of black and blue for 2-3 days, but always returned to "normal" after that.

I know others here have had problems with needles+penis. And I would only have skilled doctor do this procedure. Each must make their own decision as to what they are willing to try to find improvement.
Developed peyronies 2007 - 70 degree dorsal curve
Traction/MEDs/Injections/Surgery 2008 16 years Peyronies free now
My History

ek

Mike67-

The injection process was actually pretty trivial.  I've had far worse at the Dentist.  My Doctor (Dr Carson at the University of North Carolina) first gave me a shot to numb me up.  I think it was right at the base, maybe in my pelvis and not in my penis.  I said "I think" because I was staring at the ceiling, going to a happy place somewhere else  ;)    It was a pinch that lasted 5 - 10 seconds.  He then left while I numbed up.  It took about 5 minutes, and then I got the real injection of Verapamil.  I never felt a thing on that.   In the grand scheme of things, I'd take that all day long over root canal....!

hope this helps,
EK50

mike67

Mikey

mike67

I've had a minute to think about it. So they don't get you erect , then inject into the plaque? Just a freeze , wait - then inject into a flacid penis?
Thanks
Mike67
Mikey

mike67

Also thanks to you IWillisjr  for your information. Something to ponder prior to my next appointment. I like your ice pack suggestion.
Mike67  
Mikey

Brightdog

The more I read about the experience other people have with Verapamil injections, the more angry I get at my former urologist.

You mean most uros apply topical freezing first? Mine didn't! He just felt around, took aim and fired into my flaccid penis. Two of the four injections I received were uncomfortable but relatively painless; two of them were searingly painful and I am sure they would be contrary to the Geneva Convention if they were used on prisoners of war.

Perhaps my extremely negative experience with VI is, as I have sometimes suspected, owing to incompetent administration. I did question his methods at the time, but he assured me (as did my colleagues in the medical community) that he knew what he was doing.

MikeSmith0

Quote from: Brightdog on April 04, 2011, 02:31:57 PM
Two of the four injections I received were uncomfortable but relatively painless; two of them were searingly painful and I am sure they would be contrary to the Geneva Convention if they were used on prisoners of war.

It sounds like we went to the same doctor.. (not levine).

Quote from: Brightdog on April 04, 2011, 02:31:57 PM

Perhaps my extremely negative experience with VI is, as I have sometimes suspected, owing to incompetent administration.

i agree with you on this.... i don't think it is done the same across docs.

I was no better off after this... probably worse off but hard to say. The "sewing machine" technique was really not a good thing when it comes to trauma.  I don't see why they have to be so rough when the verapamil itself can do some of the work.  It certainly didn't help.  What happened in your case?

Brightdog

In my case, after the first three injections it seemed like the plaque was softening a bit. Then injection #4 caused the haemorraghing and everything became much worse, with the scar tissue pulling even more. And then, finally, the surgery.

MikeSmith0

woe - how did that happen?  did the needle go too far in or hit a vein or something?

crashbandit

Quote from: Brightdog on April 06, 2011, 06:06:00 PM
In my case, after the first three injections it seemed like the plaque was softening a bit. Then injection #4 caused the haemorraghing and everything became much worse, with the scar tissue pulling even more. And then, finally, the surgery.


That's horrific. I'd be freakin irrate and sour as hell for a long time. Good on you for moving past such hardship. To be stricken with something like Peyronies Disease and then go through that afterward... Your a strong dude.
Cheers

chefcasey

to ek:

Just out of curiousity, could you tell the method your doc used to inject you?  I mean did they poke the needle and inject multiple times (known as the swisscheesing effect) or was it one puncture injection of the drug in one shot?  We think the reason men have such varying degrees of success with verapamil is the different way different doctors do the injections.

Brightdog

My doctor did the one-insertion technique, with some moving of the needle (but I was not quite sure if that was deliberate or because he was unsteady).

ek

The needle itself only went in one time.  Once in, I could feel my doctor moving it around.  I typically stare at the ceiling and am also numbed up, so I don't know if he's 'swiss cheesing' or just slowly distributing the Verapamil.   I *will* say that it felt pretty smooth.   The term 'swiss cheesing' makes me think it would feel like a sewing machine down there.   It was nothing like that.


fubar

Could anyone tell me what effect verapramil is supposed to have on lapeyronie scar?It was first offered to me I declined because of all the negative feed back of its use on the forum.The goofy physicians assistant did not help matters either.All I know that it is a blood pressure medication.

He said he had done about 200 procedures outcome was 50/50.I did not believe him and then he offered me an implant.Declined that option also,  however the implant may be an option for me down the road.Hopefully all aspects of treatment mechanical or medicine will improve dramatically in the soon future.

Fubar

MikeSmith0

It's supposed to interfere with scar tissue production by inhibiting fibroblasts from maturing or from multiplying... or something like that.  

The blood pressure effects are not what matters, and it doesn't prevent calcification.  Somehow it supposedly interferes with fibroblasts -- it does this in test tubes and rats.  It didn't do it in me.

fubar

Mike

Thank you for your Answerer.I think the maturing of the condition and growth of the scar is the biggest enemy.

Fubar

fubar

So can anyone else shine light on the effect this drug has on a Peyronie's scar.what are the qualities it owns to desolve or keep the scar at a young acute age?

Fubar

Luciano

Well i read some studies on verapamil injections saying that there were like 50% that had benifits from them, but there were also like 20% that had benifits in the placebo group.
So the conclusion was, that the needle entering the plaque (thats I think what is meant with swiss cheese effect) can be beneficial whatever you inject. (but also had some patients worsening)
What I also read is that verapamil was very good against pain, as for curvature, they had slightly better results with interferon injections.

This is a study (more a review) that describes the technique as Levine uses it (its from 2002 so maybe he changed)
scroll down to "Treatment technique"
http://www.nature.com/ijir/journal/v14/n5/full/3900917a.html

in 1997 Levine has also made a study having very positive results:
http://www.jurology.com/article/S0022-5347%2801%2964224-1/abstract

But I personally think, there is a relationship between the effectiveness of VI and the skill of the doctor.

L.




Ben

I've asked about verapamil with a uro and told me that it's only useful in the acute phase. Injections can also trigger inflammation process so it may be risky. Puzzling isn't it...

ek

Actually good advice.  My uro didn't give me that warning beforehand, but research indicates its true.  If you have Peyronies Disease in the first place, then you're probably sensitive to penile trauma and your body may respond by throwing scar tissue at the trauma.  Having a couple needles stuck into your penis definitely classifies as trauma, so there's a possibility your body will put scar tissue at the entry point.  Thus potentially making things worse.   You won't know until you try, its indeed a calculated risk.

In my case, I've had 5 injections and now have a small node at the needle entry point.   However there seems to be no negative affects associated with that small node, so I'm pressing on.  Every injection has shown marked improvement.  I've gone from being functionally impotent to being *almost* back (90+%) to normal in 5 shots.   VI has been an absolute blessing!


LWillisjr

Thanks for sharing this. There are several on the forum (including myself) who have had VI's but with no improvement and no side effects. There are also those who the VI's caused additional issues. We have at least on doctor who regularly suggest VI's (along with meds and traction) and claims to have a 60%+ success rate. So is good to hear from someone who claims the VI's actually helped.
Developed peyronies 2007 - 70 degree dorsal curve
Traction/MEDs/Injections/Surgery 2008 16 years Peyronies free now
My History

Luciano

Well IMHO  if it helps or not probably depends on many factors. Of course of the individual (it helps some, some not), but I think can also depend up to a certain degree on how experienced the doc is, and what technique he is using.

I always though they were a simple injection until I saw the video of levine giving them, where he explains that he is injecting (depending on the size of the plaque) in up to 4 locations and moving the needle up and down up to 100 times while letting the verapamil flow around the plaque.
Actually I dont know if he still injects like that, if it was only to impress the colleagues at the congress, or if all docs inject like that. But I suppose the effect depends a lot of how the stuff is injected. ( Not only, but up to a certain amount)

(btw if anyone wants to see the video - you need internet explorer to watch it (couldnt get it to work with FF) - i found the link in an archive thread here on the board:
http://webcasts.prous.com/AUA2007/webcaster/template/player.asp?id=277&q=128&v=wm&tgs=&webcast=course01&CLID=2&CID=YY
the VI is around the 10:30 - 10:45)

I havent had any shots yet. 2 uros have suggested VI to me. I asked them: how do you do it. slow injection.. up and down movement etc.. Both said slow injection in one go.. and... I said no thank you. To bad I cant afford to go to the states every month to have them done by levine.


Luc

LWillisjr

Levine is my doctor, and yes this is still his techinque. He believes it is more effective than just a single site injection. So yes I am in agreement it largely depends on the skill of the specialist. I wouldn't just go to anyone for VI's.
Developed peyronies 2007 - 70 degree dorsal curve
Traction/MEDs/Injections/Surgery 2008 16 years Peyronies free now
My History

KAC

Thanks for putting up the link below.  FYI--That presentation did work in Firefox for me, but not by following the link.  Go to the site: http://webcasts.prous.com/AUA2007/ and then search for Levine.  When the presentation comes up you can choose the flash player.  It's actually a very helpful, succinct overview of non-surgical approaches.

KAC

fubar

The consensus of this treatment definately seems to be the skill of the doctor and not so much is in the medicine but the puncturing aspect of it.This leads me to believe there will better skill and less evasive treatment.

It seems that many on the forum can relate to the swiss cheese method?I curtainally do no oppose to its importance as letting blood flow as it did not before.Certainly would have a good affect for treatment as it would not agrivate the scar so much.However there is the possibility that it could.

I'm not quite sure the medicine out ways the technique.Technique may be of most importance.

Fubar

ComeBacKid

I have yet to see one study showing verapamil dissolves plaque or helps peyronies, in fact there is debate from Dr. Mulhall as to whether verapamil TV that is even gets into the penis deep enough to do anything.

Comebackid

Worried Guy

I can't see how it does much myself either.  Possible in the early stages it may stop more scar developing but it is not going to do anything to existing scar.

pvpey

Just more food for thought as I am scheduled to start this VI treatment starting this Friday and have been wavering as whether or not to proceed or try VED exclusively beforehand.

Cerveceria

I'm scheduled to start my VI treatments on 6/13 but I too am wavering considering all the negative comments that I've read.  I tried all the non-invasive procedures with no results so VI is next on the list.  If I go through with it, I'll post my results here.

pvpey

I'm going to have a serious conversation with my urologist, Dr. Paul in 2 days. I've always considered him a competent urologist, but I have no idea what's the extent of his knowledge when it comes treating Peyronies. When I initially complained about areas hardening in my shaft and the formation of an upward curve, after examination he did correctly diagnose the problem.

However my treatment regimen has been 6 months of Verapamil Topical Compound that has done pretty much nothing and the condition has seemed to worsen. I was also instructed to manipulate myself (or have sex) both when taking Cialis and not. We recently stopped the 12 month treatment after 6. His next suggestion is the 6 VI shots to see if that works and I can live with the results or "there may be no other option than surgery". Which is a last resort in my book. I was also told by his office that a nurse administers these injections and am terrified of that from what I've read here. And I will voice my concern and refer to this forum.

There has also never been any talk of some of the alternative treatments between us. Nothing said regarding some of the less invasive treatment regimens (VED, traction, exercise) that have been successful for some members of this forum. No mention of the latest medications on the market or any of the various drug cocktails now being used to treat the disease. Trust me, I have full intentions of discussing every option with him now. This is far too important not to. If he convinces me that the VI treatment is worth the risk with a good possibility of helping in my case, I may have to take the chance before the condition progresses to the point that injections will no longer have any possibility of helping. However I really want to discuss all other realistic treatment alternatives with him before making any decision. Perhaps there is that possibility he will refer me to another physician after I voice my concerns. We'll see.

I guess it's just really starting to dawn on me how devastating this condition can be. I'm in my late 40s and far too young to give up a decent sex life. To be honest I'd rather just jump off a bridge than become a eunuch. But that's just me. The disease has just started to really interfere with my sex life and obviously my confidence. Due to my curvature I'm limited to only certain positions to have enjoyable intercourse. Pretty much missionary or her on top, and even these are not like they used to be. And I have lost size. I guess I should feel lucky that I still can function to a certain degree with no pain and achieve climax. And happily oral sex has not been a problem to this point albeit awkward. But I gotta do whatever necessary to stop/slow the progression and try to correct the deformity without going under the knife. And that sounds awful expensive, but well worth it.

I'll post the results of my doctor's visit Friday night.



 

Worried Guy

Pvpey, I'm not a urologist and this is only my opinion. I don't believe VI's help that much and if they did we would know about it and there would be more guys on here singing its praises rather than saying it did nothing or made them worse. I currently visit one of the top urologists in the UK who has given me a VED routine to stop the disease progressing and to try and improve things.  They carried out the UK VED study which you can find on here.  I was told that when Xiaflex/cologenese is past I will likely be able to have it.  Xiaflex is going through the proper clinical trials and is not an experimental drug like the VI's are.  It will be past as all the people on phase 2 trails showed benefits from it.  The majority of these men were "significantly improved". I believe it may be worth you not bothering with the VI's and using VED routine to stop things getting worse.  I know it is frustrating but you can still have sex and function and if you could hold out 18 months whilst using the VED Xiaflex would be a much better option.

newguy

I'm not one to try to sway people against peyronie's treatment options (unless they're scams pills etc), but it has to be said that there are a great many more negative verapimil accounts on this site, than positive. Of course maybe those with positive reports don't come here as often, still it does seem like a risk. With treatments like Xiaflex on the horizon, I don't think it's worth taking a chance on verapamil.

pvpey


ComeBacKid

Cerveceria ,

Did you try pentox yet?  You said you tried all the non-invasive treatments so I'm curious how you made out with that?

Comebackid

Cerveceria

UPDATE:
7/18/2011
Went in for my last injection and talked to the uro.  I had major concerns with a bump forming on my right side (the good side).  So I opted out of getting the last injection.  I didn't see any reasonable signs of improvement, so to me it wasn't worth the risk.  I talked to my uro about alternatives and he mentioned to me about using xiaflix off label.  From what I've gathered there is no real data related to Xiaflix and Peyronies, so I told him I would rather wait until there are some promising results.

So, the VI didn't improve my peyronies but I don't think it made it worse (minus the bump) so I'm neutral on my opinion of offering up this option to other's who have this condition.  I'm back to just taking Cialis daily and using a stretching device.  I have a follow up with my uro in 90 days to discuss more options.  In the meantime, I'll keep monitoring this forum to provide my results and hopefully to hear about some success stories.

7/11/2011
Went in and got another shot on the left side.  This one hurt like a mother and I had swelling issues about 45 minutes after the injection.  Was really concerned so I took a half day and iced it.  Swelling went down but it took much longer to recover from the injection (about 2 days).  On the third day after the injection I started to noticed a small bump forming from the where I got the shot.  I massaged that area for about 20 - 30 minutes a night, hoping it would help.  The bump has gotten smaller but it's still there.  No signs of improvement.

7/5/2011
Went in and had another VI shot on the right side.  I'm not noticing any improvement but my girlfriend tells me it looks like I have more girth.  So I'm hopeful this is going to work out.

6/27/2011
Went in and had another VI shot on the left side.  At this point I'm hopeful to see some signs of improvement but I'm still not noticing anything.

6/20/2011
Went in and had the VI shot on the right side.  This one hurt much more than the shot on the left side where my peyronie's is.  I talked to my uro about this and he was still of the opinion that alternating sides would be a less likely chance of creating more scar tissue.  Still no sign of improvement.

6/13/2011
I had the first VI (5MG) today around 8AM EST and so far no bruising but still no visible signs of improvement.  I still have slight discomfort from where I received the shot but I'm assuming the pain will reside by tomorrow morning.  I'll be starting my daily regiment tomorrow night which will consist of 20 mins of VED w/Cialis.    I'll keep you gents posted on my progress.

Combackid,
I tried Pentox with no results which is why I'm doing the VI shots now.  At this point, I feel like a more direct approach will yield a better result but we'll see.  I have 6 VI shots planned but if I feel like they are doing more harm than good, I'll stop.

Cerveceria

ek

Xiaflex sounds like the best thing out there.  Getting into a trial is the hard part...!

Understand totally about the concerns regarding VI.  I was hesitant when I started, due to the negative press on this site.  However my back was to the wall, as Pentox did effectively nothing and I wasn't a good candidate for surgery.  I had an unbelievably nasty case of Hourglass Peyronies which rendered me functionally impotent.   So long-story-short, I gave the VI a try and my results were so positive that I started this thread.

I wanted to provide an update, since my first posting was after injection #1.   To tee it up, I had 3 spots with significant plaqueing: 1) a gigantic spot in the head, 2) a spot deep in the middle of my shaft, and 3) a rubberband-like one around the base.  I summary I was a mess.  

I've since had 7 injections which have hit all 3 spots.   The spot in the head is about 95% gone, the spot in the middle is about the same, and the rubberband at the base is about 75% gone.

Each injection seemed to do less, which makes sense.   The middle spot is still there and is painful.  However, I'm no longer impotent and am about 90% as big as I was before getting this piece-o-sh*t disease.  

In summary: if you can actually find Xiaflex, it appears to be the best.  Otherwise I suggest at least giving VI a try.  It worked for me.  Go one shot at a time.  If you think its making things worse, obviously don't continue.  My experience was that things immediately got better, so I kept going.  

Don't even want to think about what my life would be like otherwise.

Worried Guy

That sounds pretty impressive and you must be happy!! Can I ask what stage were you at when you started injections?  How old are the plaques?

ek

The rubberband plaque at the base was the oldest, probably about a year.  The middle one and the plaque in the head were each about 6 months old.   My doctor said the newer ones would respond best to the VI, but it didn't work out that way.  The most stubborn one I have is the newest.  The rubberband one immediately relaxed after the first injection.  Go figure.

fubar

Em

I have noticed that we have the same kind of damage. The rubber band effect at the bottom is also gone.I still cannot promote or think about trying them myself.To many on this forum have been damaged by them.

Fubar

Pfree

Hello,

Does anyone have any experience or knowledge of this treatment? "Intra-plaque injection of betamethasone and verapamil using a new plunger mechanism syringe with ergonomic leverage handling for the treatment of Peyronie's disease"

URL: www dot journalofandrologicalsciences dot eu frontslash media frontslash Intra-plaque%20injection dot pdf, or just google the title of the article. It is in the Journal of Andrological Sciences 2010;17:23-29.

I find this fascinating because they claim that the pressure of the Citoject plunger mechanism helps break apart the plaque. Below is a description of the procedure. It sounds pretty effective.  They also mention that the efficacy might not have anything to do with Verapamil, but with the actual breaking apart of the plaque. Perhaps even saline would have the same effect. Why haven't we heard anything about this in the US? The PDF (link above) has some photos of the Citoject and the actual procedure.

Quote"The penis is manually grasped at the level of the lesion, and a single puncture is performed. The needle is then advanced into the plaque and the drugs are slowly injected (Fig. 2). After several pushes of the plunger, a decrease in the resistance of drug down flow can easily be perceived – a clear sign that the needle is inside fibrotic tissue. Once inside the plaque, the injected fluid forms a space between plaque's fibres. In patients with large plaques, the needle may be removed and the injection repeated at several sites in the same lesion. No local anaesthesia is required for the treatment. After the injection has been completed, patients are advised to hold pressure at the site of injection for 2 minutes to avoid the risk of ecchymosis and/or haematoma. During each of the 10 treatment sessions, we changed the site of intraplaque injection in order to approach the plaque from every side. In this way, every part of the plaque received a good dose of the drugs."


Noway

When the doctor puts a needle in your penis it shouldnt give you more scar tissue or harm your penis. If the doctor puts the needle in the correct place and does it right it wont harm you. Theres a right way too do it and a wrong way.  

Pfree

Hi Noway, did you have this treatment, and if so, did you find it helpful? Thanks.

Noway

pfree No not yet injections will be my next treatment and then surgery which i dont want.  

barney

tried Verapamil cream for about a year. waste of money. several hundred per month. burned skin - always red. felt Dr just getting kickback from only one source of supplier  (Texas) with patent. i think massaging the cream in did more for plaque than drug. tried 6 months of injections with a second urologist. softened plaque and reduced angle of curvature for awhile. received lidocane injection first, then Verapamil. Dr manually manipulated plaque while numb. exhausted insurance. quit covering since experimental. plaque hardened. progressed from approx. 30 degrees to 75. Dr wanted to do surgery and i bailed on the whole idea. no pain anymore but stable angle. after two years of no treatment, have noticed plaque is app ox. 5 cm diameter. down from 10 cm or more. still searching for something that works besides butcher method or scam. i believe injections would work for less severe cases. no reactions or pain afterward. would not hesitate to have injections from a reputable Dr.. 53 years old. issue since approx. 45 years old. started with pain and slight curve. devastated for awhile emotionally. wife has been great. oral pleasure main focus. it is what it is.

james1947

barney

Welcome to the forum.
Also other people experience with Verapamil injections are not brilliant.
I am proposing you to read the forum and to see what kind of treatments people are doing and had done except surgery.

James
Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe ED.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum