Xiaflex un Europe??

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Is there a way to get this treatment in Europe after the medication was discontinued?? I live in Spain and this seems to be the best,most effective non invasive treatment.

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Hey guys,

I asked this question recently to my uro (Dr Galiano, Paris): he told me that unfortunately we should not count on it anymore, as the US Company discontinued export for financial matters, and almost no one in Europe (public authorities or health professionnal that could try to do lobby job) cares about it and will fight for Xiaflex being authorised again inside EU, in a near future at least...

Anyways, don't lose hope in the meatime, and try everything you reasonably can on this forum to improve your condition: you can and will finally find something or some things that will really work for you!!


- 35 yo, Peyronies Disease with chronic pain, general hourglassing with girth and length loss since 09/01/17.
- Pain almost cured with Hirudoid cream and diet/lifestyle changes (see my topics on this); deformity still here, but partly reduced with traction + VED.


so I need to travel to US in order to get it done, that's ridicolous
31 yrs old
Severe congenital curvature. 3 straightening surgeries
Big lump/stitch w/ left deviation after 2012 surgery
Severe ED after last one in 2014. Still crooked
Slightly improved w/ shockwave therapy
Looks like only one side of my penis works


I think unfortunately traveling to the US to get Xiaflex may be your only option. I think the manufacturer pulled it from the European market out of greed. They probably weren't getting paid enough through the national health plans so they just yanked it and went back to the States where they could rip everyone off on the cost.  
63, Peyroines since 2014, no ED, lost relationship over it. Tried Pentox, did nothing. Don't think traction will work. Lost length, bend upward maybe 30 degrees. From Jever, Germany


I´ve been quoted collagenase injections from Lyxurologia Spain. I don´t know what kind of collagenese they have, but Xiaflex (Xiapex) is also collagenase (collagenase clostridium histolyticum). I have asked if it something similar than Xiaflex, but haven´t got any answer. Anyway, it needs several injections, once a month, so for me it is not possible to travel monthly between Finland and Spain.  Maybe you lumineer78 as living in Spain can ask more information and post it here?
2 failed TURP surgery destroyed ejaculation, orgasm and sensation.
They caused severe Peyronies and nerve damage.
Erection is still left.
Peyronies since 2019, age 62.


A few months ago, I reached out to one of the representatives of Xiapex in Europe, and I was told that they took it off the market and are not going to supply it to Europe in the foreseeable future. BUT then I emailed a distributor of Xiapex in Europe, and this is what I was told:

27 y. o. Peyronies since 2020: very mild S curvature with the top part tilting to the left - 10*. Extensive scarring everywhere, wasting, hourglassing, lumps. Progressive Peyronies Disease, never stabilised. Somewhat acceptable EQ.


Hi Pete, were you able to get more info about collagenase injections from Luxurologia?
40 years. Diagnosed Peyronie by lesion. 45 degree upward and to the right. Taking talafil 5mg (3 months later) and pentox (2 months later).