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Author Topic: Dr. Landon Trost's opinion on Pentoxifyline (Pentox/trental) for peyronies  (Read 412 times)

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Pfract

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So.... given how much this drug is recommended here on the board for peyronies, i am glad he put out a video on it and if people should or should not be taking it and why there is no real data on the medication. A must watch in my opinion.

https://www.youtube.com/watch?v=YijFo1Qbtfg

Please let me know your comments about it.

Mikel7

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Very interesting.  I know that when I was taking it there was a reduction in pain and the advance of my peyronies.  For some individuals I know it does nothing.  I like it though that Dr Trost does give us information on it and he does not seem to be an advocate in either direction on using it or prescribing it.   I do like how he comes accross in his messages.
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Lump April 2020, age 60 , Dr Levine 6-26-20,
Dorsal Curve 11-1-20 , Peyronies
Vit E400mg, COQ10, ALCAR, Heat Therapy, Penimaster, Pentox, Cialis
had SNHL 7-31-20 - Stopped all Meds because ototoxicity  Heat/traction/VED are working.

Benraycamp0

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Thanks for sharing.

Dr. Trost's approach to Peyronie's disease from my understanding is:

One could argue that this is the most scientifically rigid approach to treating Peyronie's Disease since it is only using therapies with enough data backing it up. I believe each top doctor has their own treatment style. Dr. Levine is famous for his 3-prong approach (Oral + Traction + Verapamil) along with his serious doubts on Xiaflex (I don't think he uses it at all). Dr. Lue uses Xiaflex and regularly recommends Pentox as well.
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26 years old. 20 degree upward curve with slight clockwise twist. Symptoms onset Dec 20.
Dr. Levine says it's not Peyronie's Disease but a slow healing wound. Saw him Mar 21 and May 21.
Traction (PMP) and supplements per Dr. Levine's recommendation.

Pfract

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mikel7:
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"Very interesting.  I know that when I was taking it there was a reduction in pain and the advance of my peyronies.  For some individuals I know it does nothing.  I like it though that Dr Trost does give us information on it and he does not seem to be an advocate in either direction on using it or prescribing it.   I do like how he comes accross in his messages."

That's one of the things that i most appreciate in his attitude....


Quote
Dr. Trost's approach to Peyronie's disease from my understanding is:

    Acute Phase: RestoreX
    Chronic Phase: RestoreX + Xiaflex
    Issues after RestoreX and/or Xiaflex?: Surgery


One could argue that this is the most scientifically rigid approach to treating Peyronie's Disease since it is only using therapies with enough data backing it up. I believe each top doctor has their own treatment style. Dr. Levine is famous for his 3-prong approach (Oral + Traction + Verapamil) along with his serious doubts on Xiaflex (I don't think he uses it at all). Dr. Lue uses Xiaflex and regularly recommends Pentox as well.

I posted another video around here on Dr. Trost's opinion on this matter and it's almost 60 min long. It is not exactly like that. But his approach is very evidence based.He recommends medication as well, if i recall correctly. Have you seen it?

And about Dr. Levine being against Xiaflex. It is the first time i read that. Are you sure about it?

Benraycamp0

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pfract:

I haven’t seen Dr. Trost’s video, but I’d assume the video is a summary of the treatment algorithm table he has on his clinic’s site: https://malefertilityandpeyroniesclinic.com/peyronies/treatments/

You are certainly right that he is very evidence based, hence why he loves RestoreX and Xiaflex. Apparently his clinic claims to use Xiaflex more than anyone else, and Dr. Trost goes over his very specific techniques while injecting that gives him the best results (example: they only inject while erect, never when flaccid).

I have a video consult with him in June that I’m looking forward to. He’s a top Peyronie’s doc, and I’d love to hear his opinion on my case.

Actually I’m not 100% sure about Dr. Levine being against Xiaflex. There were some statements he made about it being ineffective with the first 50 patients he used it on (this was years ago), but I’m not entirely sure what his current stance on it is. I do have a check up appointment with him towards the end of May and I’ll ask him. I just know that he still uses Verapamil on most of patients which most of the other top doctors don’t seem to recommend anymore.
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26 years old. 20 degree upward curve with slight clockwise twist. Symptoms onset Dec 20.
Dr. Levine says it's not Peyronie's Disease but a slow healing wound. Saw him Mar 21 and May 21.
Traction (PMP) and supplements per Dr. Levine's recommendation.
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