Safety of low dose cialis combined with nitric oxide supplements

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lespleen

Wondering at the safety of taking low dose daily cialis with nitric oxide supplements like arginine or l-citruline. Seems a relatively common practice on the forum -- take for example the The so-called PAV cocktail -- Pentox, Arginine AND Viagra. But apparently, nitric oxide supplements can trigger a precipitous and dangerous drop in blood pressure when combined with cialis or other PDE5 inhibitors for example. But at what dosage? Any dosage?

Hawk

It is a good question that I have never gotten a good answer to.  When I took PDE5 inhibitors, I was in good physical shape with Blood Pressure on the low side (around 110/70).  I took the maximum dose of all 3 drugs (Viagra, Cialis, Levitra) at various periods in my life.  I would also take up to 2500 mg of L-arginine or L-citrulline while taking one of the individual PDE5 inhibitors.  I never had issues caused by adding L-arginine/citrulline.

However, I have a family member who passed out (totally sober) just from taking a Viagra with nothing else.

I have discussed this briefly with a pharmacist and was only told that taking them together is not advised.  I suspect, like every medication, that the effects vary with individuals.  I would proceed gradually.  If I had a blood pressure cuff, I would take my BP.  I would monitor symptoms like dizziness upon standing, etc.  I would closely monitor other blood-flow side-effects like vision change.  If they increased, I would contact a doctor before combining them again.  I had no issues.

As always, this is just what I would do as a non-professional with no medical training. 
Prostatectomy 2004, radiation 2009, currently 74 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums

pey ron

I have perfect 120/80 b.p. when I don't take anything.

This is what happens for me:
- Cialis doesn't lower my b.p. at all;
- Citrulline doesn't lower my b.p. at all;
- pentox lowers my b.p. to 100-110/60-70;
- all of the above altogether lower my b.p. to 100-110/60-70, just as if I only took pentox by itself;
- beet root powder taken when I am also taking cialis gives me a very scary arrythmia. Haven't measured my b.p. for this case and I am not looking forward to reproducing this condition just to measure it.

This is just me, I am providing this information for your reference, ymmv, don't take any risk lightly just because it seems fine in my case.
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kk1

Hi,
I think I have the same experience as yours when drinking beetroot juice and Cialis 2.5mg. Have to be careful
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Microdot

When it comes to combining low-dose Cialis (Tadalafil) with nitric oxide supplements like arginine or L-citrulline, caution is definitely warranted. From my personal experience with Cialis, I've found it effective, but it's crucial to consider potential interactions, especially regarding blood pressure.

Nitric oxide supplements can indeed enhance blood flow, and when combined with Cialis, they might increase the risk of hypotension (low blood pressure). This is particularly important if you're already using Cialis, which is designed to relax blood vessels.

As for specific dosages, there's no one-size-fits-all answer. Individual responses can vary significantly. I recommend consulting with a healthcare professional before starting any combination regimen. They can help you evaluate your specific health situation, consider any underlying conditions, and monitor your blood pressure effectively.
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