Can anyone make sense of this study and rewrite it in laymens terms

[AlterEgo]

https://pubmed.ncbi.nlm.nih.gov/23695404/



Objectives: To evaluate the effects of upregulators of nitric oxide in one patient with Peyronie's disease, after non significant improvement following intracavernosal verapamil.

Methods: A 20-years-old Caucasian male presented with penile induration in flaccid state, persistent during erection and associated with mild pain at third middle of penis. After treatment with intracavernosal verapamil for 4 months with relief of penile discomfort, followed by counseling on the use of penile extender for at least 6 hours per day, he was prescribed pentoxifylline associated with tadalafil plus levo-arginine, propionil-carnitine and Vitamin B3.

Results: After almost 2 years, the septal thickness was reduced at ultrasound evaluation after this “triple oxygenant therapy”.

Conclusion: NO-iNOS biology in Peyronie patients is the very protagonist in modulating penile fibrosis through up-regulation of NO-cGMP pathway that influences penile health by preventing and reversing fibrosis in the tunical albuginea.

[NeoV]

Increasing nitric oxide reduces fibrosis (tadalafil, arginine, and carnitine).

[AlterEgo]

So 2 years of taking pentox, cialis and arginine?  

[postrocker]

I wonder what happened after these two years. We need to discuss more if Peyronies Disease reignites after taking off pentox/Cialis/arginine/etc