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Author Topic: Can healthy tissue replace scar tissue  (Read 365 times)

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Asphyxia

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Can healthy tissue replace scar tissue
« on: December 27, 2020, 08:23:37 PM »

If i manage to get my penis back to being straight with traction, does that mean i no longer have scar tissue or does it mean that my scar tissue is now stretched and functioning like a normal tissue? People are saying traction and erections are "remodeling" i dont understand that term.

if not with traction, can we get healthy tissue to replace scar tissue ever?
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Age:23. Onset of symptoms: september 2020.
Curve mostly semi erect about 60 degrees, slight pain
Tried short & prolonged fasts, keto,carnivore, traction and most of the supplements.
Severe digestive issues, probably an autoimmune disorder

Bill2020

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Re: Can healthy tissue replace scar tissue
« Reply #1 on: January 02, 2021, 09:08:27 PM »

Would love to hear some feedback about this from some of the older members.  Any feedback guys?
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*45 y.o.
*25° lateral curve
*Lost about 2cm in length and some girth
*2 sessions of PRP - made things slightly worse
*Currently taking Tamoxifen(low dose), L-Carnitine, COQ10, Vitamin E, Cialis (daily 5mg) and TRT

anxioid

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Re: Can healthy tissue replace scar tissue
« Reply #2 on: January 03, 2021, 08:11:56 AM »

I'm pretty new to all this but i think the general consensus is yes.

Mayo clinic says:
"Traction devices place tension on the flaccid penis. The force is translated to the penile plaque and promotes remodeling via a biomechanical process known as mechanotransduction."

And this:
Penile traction therapy for Peyronie’s disease—what’s the evidence? - Usta - Translational Andrology and Urology
Says:
"Mechanotransduction, or gradual expansion of tissue by traction, leads to the formation of new collagen tissue by cellular proliferation. As a molecular result, continuous extension of the fibrous plaque causes significant increases in collagenase and metalloproteinases, and, ultimately, to fibrous plaque softening and extension."
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Age 45. 25° bend to the left, with indentation. 1cm plaque. First noticed 27 June 2020.

Asphyxia

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Re: Can healthy tissue replace scar tissue
« Reply #3 on: January 03, 2021, 01:58:18 PM »

"leads to the formation of new collagen tissue"
I cant understand if it means new scar tissue which is laid during a stretched state(and therefore more flexible) or new healthy tissue.

Im still not sure if the scar tissue even replaces healthy tissue, or if it just sits there in addition to the healthy tissue
Logged
Age:23. Onset of symptoms: september 2020.
Curve mostly semi erect about 60 degrees, slight pain
Tried short & prolonged fasts, keto,carnivore, traction and most of the supplements.
Severe digestive issues, probably an autoimmune disorder

anxioid

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Re: Can healthy tissue replace scar tissue
« Reply #4 on: January 03, 2021, 09:56:30 PM »

Hmm, i see what you mean. I have no idea either.
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Age 45. 25° bend to the left, with indentation. 1cm plaque. First noticed 27 June 2020.

DarthPronius

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Re: Can healthy tissue replace scar tissue
« Reply #5 on: January 06, 2021, 06:07:46 PM »

Here is a study dated 2011. It talks about the potential for PDE5 inhibitors (like sildenafil, aka Viagra, vardenafil, others) and pentoxyfilline to contribute to reducing or even reversing penile fibrosis. This biochemistry is a little over my head but I can get some of the big picture ideas by reading some of the conclusions (like the section titled "Peyronie's Disease").

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4149188/
"Reversion of penile fibrosis: Current information and a new horizon"

I am taking pentoxyfilline and sildenafil every day right now (along with a pile of supplements), and I've seen some of my nodules/plaques reduce in size or disappear. Unfortunately I had others appear in the past year, I think due to over-aggressive VED, and so I'm hoping the pentox/sildenafil cocktail I'm taking can help with the new ones. Overall I hope there's a chance of reducing or reversing fibrosis by taking pentox and sildenafil, and focusing on improving blood circulation by exercising and doing stretches that improve things "down south". Doing mild hand traction and massage also, and warm clothing.
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Age 34. 3 "nodules" and 2 fibrous plaques on sides since Jan 2019. Using PMP & VED

Asphyxia

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Re: Can healthy tissue replace scar tissue
« Reply #6 on: January 06, 2021, 07:34:28 PM »

Well then this leaves me wondering why this disease is considered to have no cure, and why those who fix the curve are still at a higher risk for reinjury
Logged
Age:23. Onset of symptoms: september 2020.
Curve mostly semi erect about 60 degrees, slight pain
Tried short & prolonged fasts, keto,carnivore, traction and most of the supplements.
Severe digestive issues, probably an autoimmune disorder
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