GHK Peptide

[drew67]

wonder if this would have an effect:

GHK-CuDESCRIPTION:GHK-Cu is a naturally occurring copper complex that was first identified in human plasma, but has hence been found in multiple locations such as saliva and urine. Copper peptides are small, naturallyoccurring protein fragments that have high affinity for copper ions, which are critical to normal bodyfunction. GHK-Cu has a variety of roles in thehuman body including, but not limited to, promoting activation of wound healing, attracting immune cells, antioxidant and anti-inflammatory effects, stimulating collagen and glycosaminoglycan synthesis in skinfibroblasts, and promoting blood vessel growth. There has been evidence that has shown that it acts as afeedback signal that is generated after tissue injury. First, it seems to act as a potent protector of tissue and anti-inflammatory agent that controls the oxidative damage that occurs post-tissue injury. Further, it then plays a big role in signaling tissue remodeling which removes damaged/scarred tissue and generates new,healthy tissue. However, these positive effects decline with age because the concentration of GHK-Cu in the body decreases with age. Thus, there is an increase in inflammation, cancerous activity, and tissuedestruction. Clinically, it is mostly used to decrease fine lines and wrinkles and to improve hair regrowth.


CLINICAL RESEARCH:GHK (glycyl-L-histidyl-L-lysine) is present in humanplasma, saliva, and urine but declines with age. It isproposed that GHK functions as a complex with copper 2+which accelerates wound healing and skin repair.

GHK stimulates both synthesis and breakdown of collagen and glycosaminoglycans and modulates the activity of both metalloproteinases and their inhibitors. It stimulatescollagen, dermatan sulfate, chondroitin sulfate, and the small proteoglycan, decorin. It also restores replicativevitality to fibroblasts after radiation therapy. The molecule attracts immune and endothelial cells to the site of aninjury. It accelerates wound-healing of the skin, hairfollicles, gastrointestinal tract, boney tissue, and foot pads of dogs. It also induces systemic wound healing in rats, mice, and pigs. In cosmetic products, it has been found to tighten loose skin and improve elasticity, skin density, and firmness, reduce fine lines and wrinkles, reducephotodamage, and hyperpigmentation, and increasekeratinocyte proliferation. GHK has been proposed as a therapeutic agent for skin inflammation, chronicobstructive pulmonary disease, and metastatic colon cancer. It is capable of up and down regulating at least 4,000 human genes, essentially resetting DNA to a healthier state The present review revisits GHK's role in skin regeneration in the light of recent discoveries.