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Author Topic: Relaxin-2  (Read 212 times)

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pey ron

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Relaxin-2
« on: July 30, 2020, 03:26:49 AM »

Relaxin-2 is a peptide that seems to hold a lot of promise.

https://www.pnas.org/content/116/25/12183
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5406285/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2697124/

I found a cheap and reliable source for it, but I have never injected anything in my entire life and I am already very nervous when nurses inject me in an arm. I don't think I'd be ever capable of injecting myself, and let alone in my penis...
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P1992

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Re: Relaxin-2
« Reply #1 on: July 30, 2020, 09:40:59 AM »

It seems that her action is similar to xiaflex. It would be good for them to test her for peyronie's disease to see if the results are promising.
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projectpd

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Re: Relaxin-2
« Reply #2 on: July 30, 2020, 01:04:03 PM »

interesting.. but only multiple intra artery injections had a benefit in the 1st study? ouch!.

this study used a subcutaneous infusion, but wasn't positive: https://pubmed.ncbi.nlm.nih.gov/19333948/

how cheap was your source ? i thought this kind of thing was super expensive.
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hope794

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Re: Relaxin-2
« Reply #3 on: August 01, 2020, 03:29:59 PM »

what about relaxin-2 + DMSO?
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24 yo from Italy.Peyronie's probably since 2014.Since then,penis bends of about 10-15°, with a slight twist to the left.Moderate Erectile Dysfunction since 2 years and things getting worse.From pornstar-like to moderately depressed,but still fighting for a solution.

pey ron

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Re: Relaxin-2
« Reply #4 on: August 01, 2020, 03:59:09 PM »

My source is 22.36 dollars for 10 milligrams. It's a website I trust, I have used their letrozole and enclomiphene before and they were very effective, bloodwork at hand. I also bought the relaxin-2 but I am keeping it in my freezer until one day I will learn how to self-inject.
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projectpd

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Re: Relaxin-2
« Reply #5 on: August 01, 2020, 04:08:25 PM »

Molecular weight about 6000 Da is far above usual supposed limit for DMSO of around 400. According to this, ML290 is also a relaxin agonist at 500 Da- and supposed to be low price?: (have no info on that) any thoughts?

https://bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.13656
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pey ron

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Re: Relaxin-2
« Reply #6 on: August 01, 2020, 09:59:45 PM »

Peptides are extremely delicate. I am afraid DMSO is going to damage them.
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projectpd

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Re: Relaxin-2
« Reply #7 on: August 01, 2020, 10:39:26 PM »

This ML290 isn't a peptide. but are you planning multiple injections per day?
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pey ron

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Re: Relaxin-2
« Reply #8 on: August 02, 2020, 04:35:06 PM »

sorry, didn't notice you were talking about that. Very interesting!
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hope794

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Re: Relaxin-2
« Reply #9 on: August 03, 2020, 04:50:11 PM »

Wow, nice find!!!!!!!
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24 yo from Italy.Peyronie's probably since 2014.Since then,penis bends of about 10-15°, with a slight twist to the left.Moderate Erectile Dysfunction since 2 years and things getting worse.From pornstar-like to moderately depressed,but still fighting for a solution.
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