Just finished round 2 of xiaflex - some improvement with hourglass and hinging

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Shane43

I am 59 YO, noticed weakness (hinging) at the base of penis mid 2019 and indentations early 2020, progressed to hourglass with deeper indent on right than left, and more severe hinging w/ 30 deg bend to right and 2 cm x 1 cm hard plaque in center dorsal area at base of penis. I have no ED, though I believe slightly lower rigidity at my age contributed to the bend trauma that probably caused the plaque. I have had 2 rounds of Xiaflex and this has decreased indents, and the hinge is a bit better, but penis is still too unstable for sex. First round of injections went ok, pain of injection without numbing was bad but very brief. The bruising was worse on the second injection 2 days after the first, and was significantly worse on the second round - especially the 4th injection. But nowhere near as bad as some have reported. Will get the third round in 5 more weeks.  
62YO, hourglass indent/hinging at base 30deg bend up 3cmx2cm hard plaque at dorsal base. No ED. 3 rounds Xiaflex decreased plaque/indent/hinge/bend. 1 year later, penis went from 7.5 to 5.5 in, but only 15 degree bend and no hinging.

TonySa

It's great it's starting to help.  Many docs believe adding traction between rounds increases the improvement.
PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.