YK-11

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jj21

Has anyone tried YK11? I have access to it and am thinking of doing a three month course. I believe it has the ability to reduce fibrosis.  
34 Years Old...Peyronies for 4 years. 20 Degree left and upwards curvature, major dents and narrowing, ED.

Implant + Tunica Expansion Procedure, 7th Feb 2023, Titan 22cm +1cm RTE, Partial revision 27th June 23 (fix pump, remove 10ml reservoir).

pey ron

It's very similar to DHT right? Which is a myostatin inhibitor. Myostatin is a kind of TGF-Beta1.

Finasteride suppresses DHT. Therefore myostatin is not inhibited. And penises get collagenized and become fibrotic.

So this makes perfect sense for me. I'd try it.
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popopo

Hmmm.. I honestly doubt it will do anything for peyronies. While a good level of testosterone and DHT is important for erectile function, more is not necessarily better and if you don't have low testosterone or low DHT and produce enough of it naturally you really don't need it. I would be very interested to hear about it though and I think hormones affect a lot of tissues in our bodies and like I said you need enough of them for your penis to function properly, but before hopping on this drug I would suggest getting your blood drawn first and see what your levels naturally are. Going from low testosterone or low DHT to high-normal levels will defenitely help your erections, but going from normal to high levels not so much. It would probably also shut you down so if you come of the drug your hormone levels will actually be lower for a while. I have no experience with this drug, so I might be wrong, but I know it works that way with testosterone so I assume a dht drug will shut your own production down as well. Also, I have been on TRT (testosterone replacement) before and I'm going on it again soon because I'm hypogonadal. But I never noticed my erections getting better so I doubt more male hormones will help you unless low levels are the root cause of your erectile problems. In my case hormones didn't cause this, a jelqing injury did and even a massive dose of testosterone won't get rid of the scar tissue.
Age: 25
Date of onset: 17
Symptoms: sharp pains, numbness, change in shape/size, hourglassing and discolaration from jelqing/VED usage as a teen. Diagnosed with a venous leak and possible scarring.
Treatments tried: cialis, pentox and VED didnt help

jj21

Very good points there - there's always ups n downs in trying something new especilly when it's lacking research.

I'm at that stage where i'm willing to try almost anything.

I have experience with steroids due to bodybuilding so I have a good PCT prepared and I also know when to cycle off.

I'm considering doing a 3 months course of YK11 + Keto diet followed by 3 months tamoxifen and a PDE5 to replicate the following study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4842744/

Currently seen some very small improvement (but improvement nonetheless) with 2 months on pentox, cialis daily and 2 months regular pumping and 2 weeks manual traction.

I'm not giving and am going to try everything, HGH is next so is BPC 157.

If anyone is willing to suggest anything else they think may add benefit i'm willing to try as well.
JJ
34 Years Old...Peyronies for 4 years. 20 Degree left and upwards curvature, major dents and narrowing, ED.

Implant + Tunica Expansion Procedure, 7th Feb 2023, Titan 22cm +1cm RTE, Partial revision 27th June 23 (fix pump, remove 10ml reservoir).

popopo

Good to hear you're seeing benefits from doing VED, pentox and cialis. I still take pentox but it doesn't do much. Will maybe try cialis or viagra again, but it's very expensive and I don't have that money now. HGH is also very expensive and hard to get the real deal, but could be worth it. I have heard/read about bodybuilders claiming HGH grew their penis, but it might just be boasting or placebo effect. I hope some of these substances will help with peyronies. If not I hope you'll at least enjoy the other effects like increased muscle mass, decreased bodyfat and maybe more energy/wellbeing. Try to keep working out and eat well not to let anything go to waste and try and maximize it's effect. Stay safe though!
Age: 25
Date of onset: 17
Symptoms: sharp pains, numbness, change in shape/size, hourglassing and discolaration from jelqing/VED usage as a teen. Diagnosed with a venous leak and possible scarring.
Treatments tried: cialis, pentox and VED didnt help

jj21

POPOPO - Thank you for your advice man, much appreciated.

BTW if you're suffering from ED - I noticed that a combination of Cialis daily (5mg once a day) and Pentox (3 times a day) made a significant improvement to my erectile function. Very expensive though I know - I think a generic is coming out soon.

I noticed you injured yourself using VED as a teen? Could you please elaborate on how this happened, i'm very paranoid about doing this myself.
JJ
34 Years Old...Peyronies for 4 years. 20 Degree left and upwards curvature, major dents and narrowing, ED.

Implant + Tunica Expansion Procedure, 7th Feb 2023, Titan 22cm +1cm RTE, Partial revision 27th June 23 (fix pump, remove 10ml reservoir).