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Author Topic: DMSO+X Revisited 2019  (Read 10632 times)

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Dipstick

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Re: DMSO+X Revisited 2019
« Reply #150 on: May 22, 2020, 06:35:59 AM »

Melting, what kind of Boron are you using?

I notice there are different forms of it, and is the concentration 10mg per day?

I can find Boric Acid, is that what you’re using? Is that a suitable form?
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melting

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Re: DMSO+X Revisited 2019
« Reply #151 on: May 22, 2020, 09:12:47 PM »

Melting, what kind of Boron are you using?

I notice there are different forms of it, and is the concentration 10mg per day?

I can find Boric Acid, is that what you’re using? Is that a suitable form?

Natrium Tetraborat (Na2B4O7) Which I took from capsules which have less fillers than the tablets. I only made 1 DMSO mix with it. 
A quick search I found options in germany to just buy the powder.

The pure "Boric Acid" is sold mostly non health or food related though and in germany it was discontinued for use in health products. Some still swear on it's effectiveness. BUT I guess "Boric Acid" needs to be diluted..(!) 
All sources I see on "Boric Acid" seem to be alternative health types..
 
The "Natrium Tetraborat" seems to be the safe supplement version these days.


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Daily Transdermals and Traction/VED solved my Peyronies Disease https://www.peyroniesforum.net/index.php/topic,12587.0.html (DMSO+X)

MacMathuna

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Re: DMSO+X Revisited 2019
« Reply #152 on: May 23, 2020, 02:12:14 PM »

I'm about to order DMSO from amazon, but I want to make sure I'm getting the right stuff.

What I'm looking at says it's 99.995% Pure pharma grade, non-diluted, and purified to be odorless.
Is that fine?

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27 yr/o
Symptoms presented August 20, 2019
Slight bend to the left and down
downward hinging
distal hourglassing
loss of sensation

melting

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Re: DMSO+X Revisited 2019
« Reply #153 on: May 23, 2020, 02:42:16 PM »

What I'm looking at says it's 99.995% Pure pharma grade, non-diluted, and purified to be odorless.
Is that fine?
Yes, sounds good. I had several brands over the years, always 99% quality and were always fine with it.
Of course you need to later dilute it down, as explained prior in this thread, cause using the pure solution, it will react with water in the skin and heat up causing a burn.
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melting

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Re: DMSO+X Revisited 2019
« Reply #154 on: May 24, 2020, 12:34:41 PM »

CBD
Molecular weight: 314,464 g/mol

Lot's of CBD oils and cremes available legally  even in prohibitive europe by now. Anti inflamatory properties are known and a lot of research is around on it. 
So, I guess it could help with Peyronies Disease too.

Quote
Cannabinoids suppress inflammatory response and subsequently attenuate disease symptoms. This property of cannabinoids is mediated through multiple pathways such as induction of apoptosis in activated immune cells, suppression of cytokines and chemokines at inflammatory sites and upregulation of FoxP3+ regulatory T cells.
 
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2828614/
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MacMathuna

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Re: DMSO+X Revisited 2019
« Reply #155 on: May 30, 2020, 11:39:09 PM »

Hmmmmm....

I'm mixing the DMSO with water to trigger a heat reaction, shaking the bottle, and then letting it sit until the bottle doesn't feel warm anymore.

But then when I add the asorbic acid+castor oil+xanthan mixture to the DMSO+water, the bottle heats up again like I've triggered a second heat reaction.
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27 yr/o
Symptoms presented August 20, 2019
Slight bend to the left and down
downward hinging
distal hourglassing
loss of sensation

melting

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Re: DMSO+X Revisited 2019
« Reply #156 on: June 01, 2020, 09:53:06 AM »

That's possible. I guess it's when there's more dmso than water to react with. Should be less intense the 2nd time though.
What I sometimes do to speed the process up is to have the water+dmso container/bottle in a cold water bath.

We do it a) to avoid it getting so hot that it destroys the supplements.(but realistically that wont happen for every drop of the supplement added, so no big worries)
b) to have that reaction in the container and not later on the skin.

So I think you should be good with the way you did it.
Try to put the dmso+water container in a cold water bath when adding the supplements. That should mitigate the temperature increase.

Thanks for your feedback, this is still a work in progress on how to mix and do it the best way. 
I'm waiting for a real pharmacist to get in here :)
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MacMathuna

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Re: DMSO+X Revisited 2019
« Reply #157 on: June 01, 2020, 01:30:42 PM »

I've applied the mix to my forearm a number of times over the course of the last 36 hours, and each time my skin feels itchy & tight and causes small bumps to form on my skin if I leave the mixture on my skin for more than a few minutes.
This hasn't gotten notably better with subsequent applications. :/

I do feel like the DMSO+ACV+castor oil mix I made without Lecithin (the castor oil is able to mix with the ACV, so I skipped the emulsifiers) burns less than the other two mixes which include lecithin. I'm eyeballing the measurements b/c I don't have a graduated cylinder, so it's possible this mix just has a lower ratio of DMSO to other ingredients.

I will try to make a new mix today using more water to dilute the DMSO initially. We'll see if it makes a difference.
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27 yr/o
Symptoms presented August 20, 2019
Slight bend to the left and down
downward hinging
distal hourglassing
loss of sensation

melting

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Re: DMSO+X Revisited 2019
« Reply #158 on: June 01, 2020, 02:30:10 PM »

I will try to make a new mix today using more water to dilute the DMSO initially. We'll see if it makes a difference.

This is the nr.1 way to get any burning or itching down.
Add more water. Rather start with a higher dilution and then increase the DMSO after some time. 

Intersting that the oil and ACV mix for you. They always seperated for me after letting it sit. So years ago I just shook the solution before applying which helped a bit.
Also neither lecithin or Xanthan are necessary and might not be used or used in very low amounts. It's too be able to ease application.

DMSO transdermal permeability starts already at 5%. It considerably increases with 10% and further on.
Companies that sell DMSO products like the DMSO+Aloe Vera gel I saw on Amazon seem to have settled on 70DMSO to 30other as  sweet spot. I read articles or a study where the permeability drops off once the solution is beyond 90-10.
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TonySa

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Re: DMSO+X Revisited 2019
« Reply #159 on: June 01, 2020, 06:29:33 PM »

Mac, a skin test was a great idea.  As long as you have a reaction to it, u prob don’t want to use it on your penis.
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PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

melting

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Re: DMSO+X Revisited 2019
« Reply #160 on: June 03, 2020, 12:26:05 PM »

Tony, I'm very clear on testing on the arm before use on the penis. That's standard.
It's also clear what needs to be done when the solution is too strong for the arm. Easy and logical solution.

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TonySa

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Re: DMSO+X Revisited 2019
« Reply #161 on: June 03, 2020, 08:52:49 PM »

Melting, the comment was not for you.
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PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

melting

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Re: DMSO+X Revisited 2019
« Reply #162 on: June 03, 2020, 09:07:22 PM »

Your opposition to certain methods is well known. When you post in this thread I automatically assume it's in bad faith.
If not, sorry.
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TonySa

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Re: DMSO+X Revisited 2019
« Reply #163 on: June 04, 2020, 06:05:34 PM »

Your opinion is I’m opposed to certain treatments, I’m not actually although I do usually recommend any treatment someone wants to try is accompanied by treatments w a track record, such as you added significant traction to DSMO.
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PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

Curlywurly

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Re: DMSO+X Revisited 2019
« Reply #164 on: June 07, 2020, 11:12:14 PM »

I saw talk of bathing our penises in a DMSO + X mixture.

Any reason why we wouldn’t/shouldn’t do this perhaps for an hour+ at a time or as long as possible even?
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Re: DMSO+X Revisited 2019
« Reply #165 on: June 08, 2020, 05:49:07 AM »

Is there an agreeable formula here now ?

There are lots of posts on this thread with different possibilities but I don't there's any agreement about what is good to use ? Apart from DMSO!

I'm about to restart DMSO treatment, will be adding Abscorbic acid and probably use castor oil and Cocunut Oil ( think I'll drop the Emu Oil ).   Is Aloe Vera much different to the above 2 ?

Also was using a mixture of crushed PABA, ACL (and for a time Pentox too )

What are we summarising from this thread ? the 3 or 4 most crucial ingredients to use with DMSO ?


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44 , penis trauma July 2018 leading to Peyronies. I'm attacking it though, and I will fix this!

melting

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Re: DMSO+X Revisited 2019
« Reply #166 on: June 08, 2020, 08:29:09 AM »

I saw talk of bathing our penises in a DMSO + X mixture.

Any reason why we wouldn’t/shouldn’t do this perhaps for an hour+ at a time or as long as possible even?

Like putting the whole penis in a glas filled with DMSO+X? I don't know what amounts of DMSO would enter the system that way and if it could be a danger. I guess one could try to do it for some minutes if you do it smart.. and go from there. Start with a low DMSO concentration at first,.. it will work at 5% upwards already. Monitor skin etc.

That said I had days with enough time where I painted my penis all day from a bottle which is similar I guess.
Also there are people, Peyronies Disease unrelated, doing dmso drips into the blood but obvious with such any possible risks increase also.
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melting

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Re: DMSO+X Revisited 2019
« Reply #167 on: June 08, 2020, 08:42:14 AM »


What are we summarising from this thread ? the 3 or 4 most crucial ingredients to use with DMSO ?
No, not really. But the thread was more a research thread with some brainstorming. I consider making a 2020 thread, more boiled down, easier to read.

I always felt like using every supplement(X) in an extra solution, extra glass.
The reason being, not knowing about interactions and if a "lower weight molecule" of supplement X1 and a "higher weight molecule" of X2 change how it works.
So that's why I present different X supplements that could work. At times I had 10 glasses that I cycled through.

But totally possible that using 2-3 supplements in one could work too.. idk. Check the interactions. I think Vitamin E + C can work for example.. But mixing C and Magnesium would create an interaction, possibly increasing the weight too.

Aloe Vera is different but basically helps the skin deal with the dmso. You can test how it mixes.. Castor oil itself has some good ingredients too.

PABA, ACL and Pentox are great. I always felt to using different supplements with different ways working on plaques helped(attacking from different angles). I would suggest using a stable like DMSO+Vitamin C(ascorbic acid) and then apply every other application different DMSO+X supplements.
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samsung

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Re: DMSO+X Revisited 2019
« Reply #168 on: June 08, 2020, 09:43:46 AM »

Would it be possible for someone to boil down an easy instruction type manual without having to digest a massive amount of info? Like a highlights type of thing. I would want to know:

1. What percent DMSO mixed with either water or Aloe and where to get it.

2. How to store it.

3. How many times a day to apply it.

4. What are the main things to mix it with and where to get those and how to mix them.
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45 y.o. Single. Onset of symptoms (pain-stinging like a wasp) @ 6/2018. No sudden injury. Curve developed slowly. 40 deg. dorsal. Hourglassing. Torsion to left flaccid. 4 rounds xiaflex. Restorex, DMSO+, heat, arginine, cialis, lipoic acid, vit. K2

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Re: DMSO+X Revisited 2019
« Reply #169 on: June 08, 2020, 06:08:56 PM »

Did anyone try silica gel with DMSO in the end ?

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44 , penis trauma July 2018 leading to Peyronies. I'm attacking it though, and I will fix this!

melting

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Re: DMSO+X Revisited 2019
« Reply #170 on: June 09, 2020, 08:00:40 AM »

Silica - I didn't. If you do, use some product that you can find in health stores or as natural supplement. Nothing "chemical" or "industrial".

Samsung,
I will do soon a new thread with everything boiled down to the essentials.
1. DMSO from pharmacy or Amazon. I bought a lot of different types and all worked. Pure 99% quality DMSO, phamaceutical grade. You can mix it from 5%(of the solution as in 5parts/of100parts) to 90% with Water. I did mostly use 70% DMSO + 30% water and "X". Some people need to start with ~50% or they get slight burning.
2. Brownglass, like you get in a pharmacy. Keep cool but note that DMSO will freeze above water freezing point 0°C, so outside the freezer. When using it daily you can keep it in the bathroom.
3. As often as possible. 1-3. But you can do it all day as long as the skin is OK and the supplements("X") amounts are within the healthy margins.
4. Pure Ascorbic Acid(Vitamin C) powder(every grocery store in germany has it) is the easiest and safest to use and I would recommend to start with.

50% DMSO + Ascorbic Acid(VC):
You need
-DMSO.
-Ascorbic Acid powder.
-Brown glass bottle with "glas eye dropper" ~100ml
-some glass for mixing. Easy to pour into the brown glass from.
-wooden "stick" for mixing (no chemicals, metal or plastic on it).
-Know about the dangers of DMSO. (no contact with poison, chemicals or plastics while handling or using. Pure DMSO might burn your skin)
You can get all of these easy, searching google for shopping, amazon, pharmacy etc.

Then do this:
-Fill the Brown glass bottle half(50%) with DMSO. Add 10% clean water. Move it a bit. Heat reaction. Let it cool down.
-Put clean water into the other glass.(enough to fill up the DMSO bottle). Add Ascorbic Acid powder and mix it until the water is saturated(no powder visible)
-Pour the water+Vitamin C mix into the DMSO brown glass. You can mix it with the "wooden stick" or shake it gently. Wait until any heat is gone and then you can add more ascorbic acid directly into the mix until it's saturated.

That is a very basic DMSO mix.
It's watery, runny but you can apply it with the glass eye dropper to the penis, some drops or "paint it". Let sit for 5-15 minutes. Wash off with clean water and/or use a healthy lotion ontop.

One can add some steps to create an easier to use and apply solution with oil, emulsifiers etc.

That's again a lot of words, but it's all very easy. I can do a mix in <5 minutes.
The problem is to understand handling DMSO and being smart about applying the solution, test on arm etc. There will always be some guy doing it all wrong if I just trust peoples own responsibility and hence I have to write it all with warnings etc. every damn time lol
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samsung

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Re: DMSO+X Revisited 2019
« Reply #171 on: June 09, 2020, 08:32:52 AM »

Thank you sir. Much appreciated. One last question...

I read that old Thacker's formula thread from like a decade ago and they mentioned using a clean cotton rag. They soaked the rag in the DMSO solution (ACV, DMSO and castor oil I believe) and wrapped the penis in it. It would seem this might be better than putting with eye dropper because you are really bathing the penis in the solution. Any thoughts? And if you did this, what sort of cloth would you use because I would think any cotton nowadays is going to have some sort of nasty chemical on it somehow.
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45 y.o. Single. Onset of symptoms (pain-stinging like a wasp) @ 6/2018. No sudden injury. Curve developed slowly. 40 deg. dorsal. Hourglassing. Torsion to left flaccid. 4 rounds xiaflex. Restorex, DMSO+, heat, arginine, cialis, lipoic acid, vit. K2

melting

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Re: DMSO+X Revisited 2019
« Reply #172 on: June 09, 2020, 03:04:12 PM »

Yes, that's Thackers in a nutshell. Some wrapped it around and kept it on for hours. I did it 2-3 times I think.
Was always a mess though and smelled horrible lol. That's one of the reasons the thackers wasn't used as much and as it should be.

The DMSO is gone fast in any case. Once it's on the skin it "seeps through". It's certainly possible that any supplements on the skin might penetrate for some more minutes or hours, Castor oil itself has some transdermal properties(nothing like dmso though). For near skin plaques it might be useful but generally the transdermal effect goes down exponentially after 5-15 minutes.
I always felt like doing several DMSO+X applications, (once used to dmso after some weeks), daily, possibly continuously for some hours, was very effective. I did that at least once a week. Basically "painting over" the rest of the supplements over and over.

I think it's a great idea to have now and then a classic Thackers wrap though, why not. Despite the lore story about it like from some us western movie, snake oil type, I'm convinced it worked for "Thackers" and has an effect. ACV for example has a lot of ingredients that are theoretically beneficial to peyronies. I used a lot of DMSO+ACV. (it stinks, a lot though)

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Re: DMSO+X Revisited 2019
« Reply #173 on: June 09, 2020, 05:37:07 PM »

You can actually buy Castor Oil packs which are basically a bottle of castor oil and a large cotton bandage! The idea of these is to get the castor oil into the required body part over a prolonged period with this. The penis was not necessarily what they had in mind but the same principle will apply ofcourse! Chuck some DMSO and your X ingredients in and that work quite imagine I would imagine

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44 , penis trauma July 2018 leading to Peyronies. I'm attacking it though, and I will fix this!

melting

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Re: DMSO+X Revisited 2019
« Reply #174 on: June 09, 2020, 10:19:56 PM »

Yes it will have an effect on its own.
With the DMSO we really push the supplements, castor oil, through the tissue and the plaques. It's a big difference to just the oil.
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Re: DMSO+X Revisited 2019
« Reply #175 on: June 09, 2020, 11:22:23 PM »

If you have burning pain w DMSO, or any other treatment, I recommend you stop and back off to the point of no pain.  No, melting this is no anti-DSMO and applies to any treatment strategy that causes pain
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PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

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Re: DMSO+X Revisited 2019
« Reply #176 on: June 10, 2020, 06:15:21 PM »

Just stumbled upon this thread. I was going to use the original thackers formula. Would vit c + DMSO be better?
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23, discovered I had peyronies about a year ago. About a 30 degree curve. Been seeking treatments due to difficulties with sex.

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Re: DMSO+X Revisited 2019
« Reply #177 on: June 10, 2020, 06:28:40 PM »

I bought some 10cc syringes from amazon. anyone know if these will react with DMSO?

https://www.amazon.com/gp/product/B013WWFJX0/ref=ppx_od_dt_b_asin_title_s00?ie=UTF8&th=1
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23, discovered I had peyronies about a year ago. About a 30 degree curve. Been seeking treatments due to difficulties with sex.

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Re: DMSO+X Revisited 2019
« Reply #178 on: June 10, 2020, 11:26:50 PM »

Avoid plastics, use glass only and 100% pure cotton cloths (if used) w no additives.  This is a serious concern w DMSO as it can bring contaminants into your penile tissues—not good!
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PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

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Re: DMSO+X Revisited 2019
« Reply #179 on: June 11, 2020, 06:08:36 PM »

Hi Melting

I've received Ascorbic Acid that I ordered on the back of this thread

Haven't used it with DMSO yet . Before I do, are there studies or results that suggest this is good for this purpose?  Or is it just that it has a low molecular weight ? I wanted to check this before I started using it

The thought also crossed my mind that excess vitamin C ( ascorbic Acid ) is thought to be factor in causing the peyronies scars to develop in the first place. As excess Vitamin C can lead to excess Collagen production I do believe. And at the time of injury ( or days afterwards ) t while he body is attempting to heal , the excess vitamin C can then cause excess Collagen can be produced at the site of healing. That's the theory anyway I believe. In fact, at the time of my Peyronies injury I was taking high strength Vitamin C timed release capsules every day ( 1500mg I think ). May have been a factor or just a coincidence .

So just wondering whether this could be an issue with the Ascorbic Acid. Or if is conversely beneficial during stable phase peyronies once the initial scars/ plaques have formed

Any thoughts or knowledge on this ?
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44 , penis trauma July 2018 leading to Peyronies. I'm attacking it though, and I will fix this!

melting

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Re: DMSO+X Revisited 2019
« Reply #180 on: June 12, 2020, 07:23:59 AM »

I bought some 10cc syringes from amazon. anyone know if these will react with DMSO?

https://www.amazon.com/gp/product/B013WWFJX0/ref=ppx_od_dt_b_asin_title_s00?ie=UTF8&th=1

As you probably found out already, plastic can react with DMSO. But there are certain plastics that dont react at all. Some sell DMSO in these plastics.
Here's a big list: http://tools.thermofisher.com/content/sfs/brochures/D20480.pdf  of plastics and DMSO is down the line.
HDPE plastic doesn't react for example.
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melting

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Re: DMSO+X Revisited 2019
« Reply #181 on: June 12, 2020, 07:28:28 AM »

If you have burning pain w DMSO, or any other treatment, I recommend you stop and back off to the point of no pain.  No, melting this is no anti-DSMO and applies to any treatment strategy that causes pain
BS. There's a specific reason well known reason why it burns. If you put it undiluted on the skin it will burn. 
You need to dilute it and everyone paying attention knows that. It's easy.

I explained it in detail RIGHT ON THIS PAGE which you conveniently OBFUSCATE for some phony reason, but again, it's transparent, you are here in bad faith promoting nonsense all over the place.(like traction while you are inflammed, dangerous and dumb).

The only thing you promote is implants..(its for old people who have no idea how to fix themselves, like you) even to young totally fixable guys...I don't like you.
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melting

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Re: DMSO+X Revisited 2019
« Reply #182 on: June 12, 2020, 07:59:54 AM »

There are NO direct PEYRONIES STUDIES with ANY of the talked about DMSO+X supplements(I know of)!!!!! 
And most probably there never will be. (no profit in this)

If someone doubts it, like the Tony's of this forum, then research it or don't do it and instead get your dick cut up and get an implant, easy way out. This here is the hard way. All your own responsibility. That's not directed at you "Fix This"! Just getting riled up about some ignorant people. Sadly lot's of dummies who can't take responsibility for their own life and cry when they do their crap wrong blaming others.

ok.. :)

So just wondering whether this could be an issue with the Ascorbic Acid. Or if is conversely beneficial during stable phase peyronies once the initial scars/ plaques have formed

Any thoughts or knowledge on this ?

I promote it as the prime DMSO+X mix cause it's easy to create, cheap and VItC is completely harmless, almost impossible to overdose or hurt anything with it. It's the safest supplement - Ascorbic Acid.

You can research vitamin C in connection with tissue, veins, fibrosis, scars, etc. and make a logical conclusion towards peyronies..
It's anti-inflamatory, it's an antagonist to calcium desposits, needed to build healthy FLEXIBLE tissue..

To me it makes no sense to assume that vitamin C creates faulty tissue. I doubt that the body will overproduce collagen just cause VitC is there. If you leave out the building blocks of Collagen you will get faulty collagen.
Without vitamin C(and others) the body will patch up the inflamation or injury with other materials resulting in fibrotic clumps.

It's interesting you took C and still got peyronies. But most C we orally take in is gone fast, - short half life. That's why coating the site of the plaque with it as often as possible transdermaly is much more effective than having it systemic and with low blood flow to the penis it wont reach the 'building site'. (it's still good to also have VC systemic taking it orally)
Also Vitamin C, while essential, obviously other supplements/chemicals are involved too.

At best you would start DMSO+Ascorbic Acid to get used to the procedure, to know how much you have to dilute the DMSO etc.
Then you would start some other solutions with supplements that help in your situation. For example dmso+Iodine or dmso+Magnesium.
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melting

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Re: DMSO+X Revisited 2019
« Reply #183 on: June 12, 2020, 08:02:20 AM »

I finally blocked Tony and his trolling ignorance.
If he keeps posting nonsense on this thread, know that he has no clue about DMSO+X.
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sinvanio13

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Re: DMSO+X Revisited 2019
« Reply #184 on: June 12, 2020, 08:51:05 AM »

Hi, @Melting
i am coming back after a confinement absence, ^^ , i am about to test asc Acid and Iodine in seperate days.
I have a question about Iodine, i found Harmonic Innerprizes Nascent Iodine at amazon, but coming from canada/usa, quite expensive , did you manage to find an equivalent without unsuitable additives ?

Another point  there was recently a post promising about oral Copper Supplementation (depleted by zinc supplementation)
did you investigate that topical  or orally? https://www.peyroniesforum.net/index.php/topic,13065.0.html
 thanks
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hope794

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Re: DMSO+X Revisited 2019
« Reply #185 on: June 12, 2020, 06:45:35 PM »

Questions for melting (and for the other users who cured Peyronie's with this method):

1. I've understood that i have to apply DMSO+X at least 3 times a day, for 10minutes. Then i wash my penis with normal water, for example using the water from a sink?

2. You've spoken about Iodine, and u said that it is antinflammatory. But i found poor evidence about it online. Can you please share something of the papers you read here? :) Furthermore, where to buy iodine? I didnt find anything on amazon, except for tablets. Should i break them and mix with DMSO?

3. Should i wash my penis with soap too, after i washed the DMSO away with water?

4. Should i apply some kind of oil or cream to give reliefe to the penile skin in the night? For example castor oil, or aloe vera, (without DMSO)?

Thank you really much!
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sinvanio13

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Re: DMSO+X Revisited 2019
« Reply #186 on: June 12, 2020, 08:14:37 PM »

Questions for melting (and for the other users who cured Peyronie's with this method):


2. You've spoken about Iodine, and u said that it is antinflammatory. But i found poor evidence about it online. Can you please share something of the papers you read here? :) Furthermore, where to buy iodine? I didnt find anything on amazon, except for tablets. Should i break them and mix with DMSO?

i sent you a private message for the link on amazon for the brand i ordered this week (expedition from the USA eligible to prime delivery)
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hope794

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Re: DMSO+X Revisited 2019
« Reply #187 on: June 12, 2020, 09:53:45 PM »

Thank you very much bro, but i didnt receive any PM yet..!
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24 yo from Italy.Peyronie's probably since 2014.Since then,penis bends of about 10-15°, with a slight twist to the left.Moderate Erectile Dysfunction since 2 years and things getting worse.From pornstar-like to moderately depressed,but still fighting for a solution.

Fix This

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Re: DMSO+X Revisited 2019
« Reply #188 on: June 13, 2020, 05:52:24 AM »

Hi Melting

Thanks for your reply. No I was refering to general studies regrding Vitamin C and peyronies rather than using DMSO and transdermal. As you rightly say I believe, that transdermal application of anything should get much more of the product to the plaques than orally. So anything that applies to a particular agent when taken orally should in tehrory apply when applied transdermally. Only with much more efficiacy ( we think! ). Anyway, I'll look into the Vit C a little bit more I think before I use that one

Can I ask, what sort of curvature and/ or narrowing did you have before you started this treatment ? And how much improvement have you had since starting your DMSO + X treatments ?

I'm going to go a bit heavier on this DMSO treatment (+X) and I think your idea of having many separate bottles with individual substances in and rotate them is excellent. I'm going t order some more bottles and try some of the other agents mentioned here

I already have Castor Oil, PABA, ALC, Vit E, Ascorb Acid, Pentox, Coconut Oil ( dropping the Emu Oil I also have )

Can you recommend any of the other compounds mentioned on this topic ? Iodine and Magnesium ( any type ? ) have been mentioned recently, but there are many more reading back through this topic that have been mentioned once , but not again.

Have you or anyone else here had any particular success with any specific ' X ' products ?

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Fix This

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Re: DMSO+X Revisited 2019
« Reply #189 on: June 13, 2020, 06:58:09 AM »

Sorry , another question Melting. I need to order some more glass bottles. Is there a reason that you mention brown bottles rather than clear or blue ones ?

Thanks

Fix
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sinvanio13

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Re: DMSO+X Revisited 2019
« Reply #190 on: June 13, 2020, 08:25:33 AM »

Thank you very much bro, but i didnt receive any PM yet..!
sorry i dont know what t happened cant see my message in sent items mailbox.
i sent you again plz confirm you ve got it
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melting

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Re: DMSO+X Revisited 2019
« Reply #191 on: June 14, 2020, 02:38:13 PM »

Hi, @Melting
IODINE

I think I would pay for 40€ for 30ml. That's very expensive and if you're not rich for basically 1 time buy. I used 1 bottle 50ml I think over several months as part of a multi DMSO+X range of bottles.
You probably can use the "LUGOL's" Iodine too. Obviously read up a bit on it on google etc. and be aware of dosage etc. and test  llittle bit on arm before using it a lot.

COPPER
Yes and if you make forum wide search for copper + DMSO you will find it discussed by me and others. There are many copper versions. I had one that I can't remember.. Copper sulfate maybe.. With minerals like iodine or copper be aware that overusing them can deplete other minerals.(but hard to do with the amounts we use in dmso+x in most cases)

Also wise to use Vit C and for example iodine not in same bottle or same time cause they interact with each other too much.
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melting

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Re: DMSO+X Revisited 2019
« Reply #192 on: June 14, 2020, 03:07:17 PM »

Hi Melting

Yes, whatever might work orally might work transdermally, of course molecular weight and how it theoretically works needs to be understood. IDK maybe something works better when moving through stomach etc.

Vitamin C is the safest. Hard to do anything wrong with it. The body loves it. Only we and a handful of animals don't produce our own Vitamin C.

- Several places on shaft hourglass and slight bend and a "torque", and soft places with no erection. All solved as explained several times here. I'm 100% functional. Traction and VED very important for me. I also talked about.

-Magnesium and Vitamin C were a staple for me. Also in my last run months ago, to get rid of the last plaque remains, I felt like "Natrium - Thiosulfate", also discussed here, had a great impact.

-It's hard for me to nail it to one supplement as I most times used several. I believe all of them worked in some form.
There most probably is an optimal way, how to cycle through supplements for best non negative interactions and best positive reactions related to where the peyronies stage is.
That would need a lot of professional people to nail down. I attempted discussing active and established plaque supps on this thread and someone chimed in. page 2-3 I think. Anti Inflammatory during active phase and anti-calcification/scar/fibrosis during hard/established stage. BUT there are good reasons to use both all the time, just maybe a bit less.

brown bottles

light - Supplements degrade slower in brown glass.
Ascorbic acid within hours/days when put in water and in direct light. In dark 2-3 weeks.
Best, cool, dark but not below 6°C cause DMSO freezes earlier than water(0°C)

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melting

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Re: DMSO+X Revisited 2019
« Reply #193 on: June 14, 2020, 03:33:30 PM »

Questions for melting (and for the other users who cured Peyronie's with this method):


1. Most the times I mix what remains on my penis with a good lotion and then the skin is OK and everything is gone.
But if you have safe water from the faucet you can use that too. Like going into the shower after application. Just dont use some super aggressive shampoo right over it.

2. For example: https://pubmed.ncbi.nlm.nih.gov/19168293/ , best way is to search for scars + X(iodine) , keloids+X, plaques+X, fibrosis + X, inflammation+X , tissue+X etc.

3. answered in 2.

4. Yes. Helps a lot. Can apply right after DMSO too.
Everyone has to test what works for their skin in what concentration.

Nascent Iodine or lugol's. It's liquid. Might have to ask pharmacy online or local.
Problem with grinding tablets is that they have a lot of filler material. Not necessarily harmful. The result most time is that you have remaining clumps in the solution or on your skin after application. I did that for some supplements, it's messy, but possible.

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hope794

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Re: DMSO+X Revisited 2019
« Reply #194 on: June 14, 2020, 04:57:52 PM »

Thank you for the reply!
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Bent Ding Dong

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Re: DMSO+X Revisited 2019
« Reply #195 on: June 16, 2020, 06:53:11 AM »

I'd love to try DMSO again but the garlic smell coming out of my skin and breath is a bit much especially when you have to go to work smelling all day. If anyone knows of a non smelling DMSO can you let me know? I've heard some say pure DMSO doesn't have as much smell.
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projectpd

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Re: DMSO+X Revisited 2019
« Reply #196 on: June 16, 2020, 02:40:11 PM »

I've bought DMSO twice , first time claiming 99.8% pure in a cheapy looking plastic bottle and later "upgraded" to 99.99% pure in a nice brown glass bottle. the 2nd one was solid (jelly like) at a temperature that the 1st one wasn't and came with a note saying that if so , this was a sign of its purity, which seems reasonable. But both of these only have a rather faint (to me, I don't have the best sense of smell though) odour that is not unpleasant at all. Also all the reports on it say you can taste garlicy
 flavour in the mouth within seconds of putting it on your skin, but I'm not sensitive enough to have detected this! I know some people have much more sensitive noases/tastes.  However I have a dmso+x style concoction (mostly a la Thackers) with #2 that truly reeks of a garlicy odour. So beware, probably depends what it reacts with.

THere are other things that have been studied for transdermal properties, it's a huge volume of research .

There is a ton of research on variations of liposomes, lots of "X-somes" with variations on X. Some of the latest are Invasomes (adding small fractions of terpenes, which are in essential oils such bitter orange, lemon, lavender. TransEthosomes (adding significant fractions of Ethanol -  the optimal proportions exactly match that in vodka!). These typically use phosphatidyl choline (a component of soy or sunflower lecithin) and a small fraction of surfactants (such as in detergent, but there are pure  and natural(ish) options). These make the vesicles very flexible so they can squeeze between skin cells without breaking up.  It's easy to make liposomal vit C at home , there are youtube vids on this and at least one that actually demonstrate with a microscope that the liposomes are small enough. Therefore I believe many of the more effective variations are probably easy to make. Ethanol has an advantage that it will help to preserve the mixture. otherwise it could go off in a few days.  Ethanol does sting however.
In a study on transdermal serrapeptase, DMSO and Isopropyl Myristate were credited with effectiveness, in a comparison where many other candidates didn't.
serrapeptase has a huge molecular weight. I got some ! it has no smell at all.

Also other general factors are bound to be relevant such as pH, temperature, hydration. Not always in the most obvious way, I read a paper where hydration was thought to be detrimental to the agent's absorption, purportedly it might detract from the hydration gradient that  helped that substance to penetrate.

I have been wondering if other factors would also help, such as while using a stretcher (opens up spaces between skin cells) , VED (same).

3Mhz ultrasound (cheap devices available).

Percussion massager. These go up to 10,000 Hz. Don't really know if this should help, just a hunch.


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Fix This

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Re: DMSO+X Revisited 2019
« Reply #197 on: June 16, 2020, 04:26:21 PM »

Thanks for your replies Melting. And good post too ProjectPD

Has anyone else experienced any lines on their penis after DMSO use ?

I'm seeing a few horizontal lines / wrinkles around the area of the plaque that I've been targetting a lot more in the last week or so. I'm fairly sure I don't recall seeing these previously. I suspect I may have used a bit too much DMSO in some of recent mixes. I'm hoping these are temporary. Will be moisturising them pretty intensely and may lay off the DMSO until I can see an improvement in them

I've always left the DMSO and X on the skin to dry and just left it on until next shower. I think I saw some mention of washing off once it had dried on here? Just wondering whether this might be a factor here
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hope794

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Re: DMSO+X Revisited 2019
« Reply #198 on: June 16, 2020, 06:25:10 PM »

Fix this, probably rough veins?

It happens to me when i got pretty good erection (thanks to pde5i). I notice things that normally i dont notice due to the more engorgement. DMSO improves blood circulation: maybe you're experiencing this?
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melting

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Re: DMSO+X Revisited 2019
« Reply #199 on: June 16, 2020, 09:46:40 PM »

If the skin is tight then its most probably dried out.
If it's soft watery then most probably fluids/parts of the solution accumulated due to the dmso opening up the layers.

Normal to run into skin issues after some continuous applications. Cut back or use lotions/etc. that help the issue at hand.
I had to stop several times after some weeks to let the skin catch up. Depends a lot on the X. Ascorbic acid can accumulate in skin if applied daily. In nails it will store and slowly degrade changing color.(which is harmless, just a different form of Vitamin C).

I applied DMSO+VC for some days with my hands and I had for some days yellowish nails. Looked weird lol

I wonder how dmso+ anti calicification agents would influence nails that have these white spots in them(I think its calcium deposits?)
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