Topical Nifedipine and other Raynaud treatments

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Hontas

The best results i got was from Verapamil cream, but i wonder why nobody recommends nifedipine as it is more effective on perivascular calcium channels rather than heart related calcium channels. Dihydropyrimidines(such as Nifedipine) could act in even more potent way compared to Verapamil. I am also starting 50 mg Losartan treatment in combination with Verapamil after getting tested for my blood pressure. It seems like i have something similar to scleroderma and someone with scleroderma(or systemic sclerosis) could help a lot if anyone here has it.

philtered

  Is there a link between peyronies and reynauds? i've had renauds all my life and both my sisters suffer as well.
AGE 59
Acute since  Dec 2017
VED, traction & supplements
Went from 30 degree curve to 80 during acute stage  stabilized since May 2019
Curvature calculated at 80 degrees by Dr Ralph from emailed photo.
Titan  22cm with 1cm RTE's Prof ralph Feb 2022

samsung

Yup. And Ehlers Danlos. And dupuytrens. And a few others. I have Raynauds. When I was a kid it was quite challenging to feel up the girls with ice cold hands. Didn't stop me though.
45 y.o. Single. Onset of symptoms (pain-stinging like a wasp) @ 6/2018. No sudden injury. Curve developed slowly. 40 deg. dorsal. Hourglassing. Torsion to left flaccid. 4 rounds xiaflex. Restorex, DMSO+, heat, arginine, cialis, lipoic acid, vit. K2

Hontas

F~@< this crap. F~@< it. F~@< all of it. Everytime i use a treatment it reverses a bit and then my body adapts and develops a resistance and it become ten times worse. F~@< this crap.  

Bent Ding Dong

@Hontas, have you tried rotating anything that works for 1 day, then onto the next thing that works the next day then onto the next so that you don't build up a reaction to it?
Age, 40's.

Had peyronie's for more than 10 years. Developed glans lump, then had poor erections and soft glans.

Made a lot of progress over the years with diet and avoidance of sugar and high carbs. Still have the lump but it's much smaller now.

Hontas

Has anyone tried topical pirfenidone, rosiglitazone or tacrolimus/pimecrolimus? I am going try them starting with rosiglizatone. Currently on High dose colchicine + Steroid cream regimen.

melting

Hontas you throw out a lot of interesting chemicals!

The things you mention, how do you use them?
pirfenidone, rosiglitazone or tacrolimus/pimecrolimus , nifedipine?  

Cause if you use them as a topical then the question is what the carrier is in the creme. If it's for topical ailments then it might not be designed to go deep like we often need(into the tunica).

I checked their molecular weights and they're all low enough to be carried by dmso transdermally. (Tacrolimus with 800g a bit on the high side.)



Daily Transdermals and Traction/VED solved my Peyronies Disease https://www.peyroniesforum.net/index.php/topic,12587.0.html (DMSO+X)

Hontas

Forget nifedipine, i am going to try amlodipine. It is a longer release substance. Yes its going to be mixed with DMSO.

Irishpeyroniecure

Have you tried infra red light, niacin, marijuana, cbd?
Exercise regularly?? Especially with weights? Ever considered testosterone injections?
You seem poor so human growth hormone is likely out of your budget.

I have an unbeatable cure but it takes a little money to buy these things  
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TonySa

It seems like a language barrier, just saying he may not be able to afford the price oh it.
PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

Irishpeyroniecure

Quote from: samsung on January 05, 2020, 01:33:11 PM
And here he calls a member "poor." When are you mods going to ban this p.o.s.?

You'll never beat this thing as you're stupid and not willing to listen. I have solid info in my other thread. I bet you don't even exercise, loser. You expect everyone to do it all for you. Pathetic.  I'm trying to help people and it's frustrating nobody seems motivated to beat this. That's why I beat it and you won't. Different mindset. Well good luck on having a long life of no sex buddy  
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TonySa

Irish, are you able to refrain from name calling on this forum?
PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

Godisreal

Stop calling each other losers. I promise you that stem cells will be the cure. There's no need to argue. All of those who have implants when young are stupid. If you are old, I wouldn't wait since, yeah you're old. We are in the 2020's, just think about how medicine and science skyrocketed in the 2010's. It's only gonna skyrocket ever more now. Stem cell surgery will be mandatory treatment within 10 years when it comes to Peyronies Disease-patients.
F*ck everybody who thinks otherwise.  
30 degree dorsal curve, immobility and heavy loss of girth.
My body seems to get very inflamed when I masturbate too often or eat unhealthy.
Using antioxidants, Pentox and hirudoid cream, as well as manual traction, heat and Cialis.

Irishpeyroniecure

Quote from: Godisreal on January 06, 2020, 09:43:46 AM
Stop calling each other losers. I promise you that stem cells will be the cure. There's no need to argue. All of those who have implants when young are stupid. If you are old, I wouldn't wait since, yeah you're old. We are in the 2020's, just think about how medicine and science skyrocketed in the 2010's. It's only gonna skyrocket ever more now. Stem cell surgery will be mandatory treatment within 10 years when it comes to Peyronies Disease-patients.
F*ck everybody who thinks otherwise.

Oh You're dead right. But if you start exercising and doing the other things like IR and sauna you'll begin to see improvement within a day or two  
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Godisreal

How would I see improvement in form of reduced penile curvature/rescued plaque size with exercise and sauna? Please share information.  
30 degree dorsal curve, immobility and heavy loss of girth.
My body seems to get very inflamed when I masturbate too often or eat unhealthy.
Using antioxidants, Pentox and hirudoid cream, as well as manual traction, heat and Cialis.

Irishpeyroniecure

Quote from: Godisreal on January 06, 2020, 11:10:06 AM
How would I see improvement in form of reduced penile curvature/rescued plaque size with exercise and sauna? Please share information.

The heat will improve circulation and in turn speed up healing. It takes little effort to go to a spa for a week and see if it helps. Do you want me to hold your hand? Just do it.

And more importantly, go on amazon and find an infra red light - can be just a basic cheap one with a stand will do. Try to get one with range of around 800nm. Infra red is now shown to penetrate skin more than UV (up to several cm perhaps inches). Look up Michael Hamblin, a professor at Harvard, who intensely researches photobiomodulation.

I am a member of an infra red light therapy forum and I've seen tonnes of people tell their stories of it healing joint damage, muscular tissue, arthritis and so on.

I'm putting you in the right direction.

I'm not knocking the DMSO, this may help. I haven't tried it. I know massaging gently with coconut oil helped break my scar tissue up much more rapidly. Even after Reinjury.

You MUST exercise as well. Cardio is vital. 30-40 mins 4-5x weekly


Golden tip:
Smoke a good strain of weed before cardio, sauna and jacuzzi as it greatly increases circulation
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Irishpeyroniecure

If you want to have raging hardons you better get serious about lifting weights and taking supplements
Arginine 3000mg x 3 daily at least
Add niacin starting at 500mg if you feel you need it
Obviously Viagra 100mg to start with - use as little as need be though

Icing on the cake:
Find testosterone and human growth hormone source
Do a beginner cycle  ;)
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Irishpeyroniecure

I forgot...CBD oil at 4% helped healing imo especially taken with the marijuana
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Godisreal

While I hold your hand, you can hold my balls since I bet your own balls has shrunk to microscopic size because of the roids, Mr. Arnold.
Nah but I appreciate your tips tho, but I'm a man of science. I've never read anywhere that marijuana increases blood circulation. It has significant health benefits, that's for sure. But not on circulation. Please link a study on marijuana and blood circulation if I'm wrong.
Sauna, jacuzzi (hot water) & cardio all increase blood circulation.
And how come I've never heard of infra red lights, on here? You mean it would break down scar tissue? Man, that doesn't sound right. Also, doesn't infra red lights have terrible effects on eyes. I believe it can cause black dots in your eye-lenses.  
30 degree dorsal curve, immobility and heavy loss of girth.
My body seems to get very inflamed when I masturbate too often or eat unhealthy.
Using antioxidants, Pentox and hirudoid cream, as well as manual traction, heat and Cialis.

Godisreal

How am I supposed to buy CBD oil in a country where cannabis is illegal? If you could help me out on that, (I don't care about the law) I would be very happy.
I'm a marijuana smoker already, and I would love to include CBD oil in my treatment.
30 degree dorsal curve, immobility and heavy loss of girth.
My body seems to get very inflamed when I masturbate too often or eat unhealthy.
Using antioxidants, Pentox and hirudoid cream, as well as manual traction, heat and Cialis.

Irishpeyroniecure

Quote from: Godisreal on January 06, 2020, 12:38:41 PM
While I hold your hand, you can hold my balls since I bet your own balls has shrunk to microscopic size because of the roids, Mr. Arnold.
Nah but I appreciate your tips tho, but I'm a man of science. I've never read anywhere that marijuana increases blood circulation. It has significant health benefits, that's for sure. But not on circulation. Please link a study on marijuana and blood circulation if I'm wrong.
Sauna, jacuzzi (hot water) & cardio all increase blood circulation.
And how come I've never heard of infra red lights, on here? You mean it would break down scar tissue? Man, that doesn't sound right. Also, doesn't infra red lights have terrible effects on eyes. I believe it can cause black dots in your eye-lenses.


I'm not going to hold your hand through the research. Hgh and other things I mentioned all increase nitric oxide - the weed is a vasodilator you dumbass.
You're a man of science? I'm an electronic engineer. I'm also a man who dabbles in the underworld. That's how I got all my gear so cheap to combat this and defeat it with ease while you cry here on a message board you virgin. See if I care.
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Irishpeyroniecure

I misread your post. My apologies. I am in a rush today.

Cbd can be easily purchased online I use cibdol 4%

Dude if you can source weed you can find cbd surely. It's legal in crushed form in a lot of countries now. Find a way to get it

Human growth hormone I can point you in the right direction  
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Godisreal

Calling someone with Peyronies Disease a virgin is very disrespectful. How serious is your case? You said you're cured? Did you have a curve? A big plaque? You know what forget it. It's impossible to speak sense into someone on roids lol
Anyhow; in my country, there's a portable infra-red sauna that sells for around €300.
Would that be beneficial, you think?  
30 degree dorsal curve, immobility and heavy loss of girth.
My body seems to get very inflamed when I masturbate too often or eat unhealthy.
Using antioxidants, Pentox and hirudoid cream, as well as manual traction, heat and Cialis.

Irishpeyroniecure

Quote from: Godisreal on January 06, 2020, 12:55:22 PM
Calling someone with Peyronies Disease a virgin is very disrespectful. How serious is your case? You said you're cured? Did you have a curve? A big plaque? You know what forget it. It's impossible to speak sense into someone on roids lol
Anyhow; in my country, there's a portable infra-red sauna that sells for around €300.
Would that be beneficial, you think?

I had scar tissue along shaft. Curvature was not too bad - more tissue damage. It was ongoing for nearly a year coming and going. My cocaine habit made it worse. Once you increase blood flow to the levels I dud everything pops back into place like a balloon.

You don't need expensive lamps - get a Philips 250w infra red lamp they're like 10 dollars
Use it every day for at least 20 mins x2 daily - every second day if too much

Must be close - 1 foot roughly to get the best benefits
However this is debatable as I experimented at farther ranges for I.e. an hour while reading and massaging my schlong or watching some good porn to help "pump" me up


Wear goggles if concerned about your eyes Einstein
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Irishpeyroniecure

I don't think I'll be posting anymore as I'm starting to feel anxiety thinking about having it. I've given plenty of info on how to beat it. I think I'll sign off now. Little Asian cocked Samsung I can do no more for you, my dear  
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melting

Can we please delete all off topic posts from and aimed(like this one) at this "Conor McCregor" wannabe? (including in my signature thread?). You allowed him too much leeway already.  

Most people with this issue don't have the nerve to work their way through posts that have no information and useless banter to get to the meat of the threads. Time and time again threads are cluttered with unrelated nonsense that wastes time.
Daily Transdermals and Traction/VED solved my Peyronies Disease https://www.peyroniesforum.net/index.php/topic,12587.0.html (DMSO+X)

Irishpeyroniecure

Quote from: melting on January 06, 2020, 01:07:58 PM
So can we please delete all off topic posts of and around this "Conor McCregor" wannabe? (including in my signature thread?)  
Most people with this issue don't have the nerve to work their way through posts that have no information and useless banter.

Infra red and saunas and hgh are banter?

I am done here anyway. Wasting my time with betas
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melting

No one cares about your alpha cocaine dreams boy. F~@< off
Daily Transdermals and Traction/VED solved my Peyronies Disease https://www.peyroniesforum.net/index.php/topic,12587.0.html (DMSO+X)

Irishpeyroniecure

Quote from: melting on January 06, 2020, 01:12:08 PM
No one cares about your alpha cocaine dreams boy. F~@< off

I bet you're a cuck who likes what merkel did to your once great nation  
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Godisreal

This Rich Piana wannabe obviously gets satisfaction from dissing and disrespecting other forum members, because he was bullied when he was a young boy. And now he takes out years of suppressed anger on innocent Peyronies Disease-sufferers, with his useless identity hidden too.
This combined with cocaine & anabolic steroids have obviously f*cked up your poor brain, lil fella. Sad to see that you couldn't feel like you was enough without pumping needles into your arm every week. Post some pictures of your balls, man, I want to see how pathetic and microscopic they look after years of extensive steroid-usage.
Nobody wants your disgusting attitude here, so log out and don't come back.  
30 degree dorsal curve, immobility and heavy loss of girth.
My body seems to get very inflamed when I masturbate too often or eat unhealthy.
Using antioxidants, Pentox and hirudoid cream, as well as manual traction, heat and Cialis.

Irishpeyroniecure

To those of you who follow my directions - you will easily beat it. Best of luck!! Lots of love  :-* :-* :-*
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Godisreal

The funniest thing is, I too have big dreams and my young age is the only thing that holds me in this b*tch of a country. I know stem cells will cure me, doesn't have to be legal. I know that most professionals would take a bribe. Funny how I called them professionals, but they sure know what they're doing. Some of them at least.
The law is to me; a book made to keep the sheep in line. I'm no sheep, but there's nothing wrong with being a sheep - if that's what you want.
You have an attitude that only roid-freaks have, I bet that you're bald too. And when you're on the cycles you feel unstoppable and like nothing can brake you down, right? How about the times when the steroids is going of out your system? You don't feel too good then, do you? You become the b*tch that you really is without your roids.
There's nothing you can do to stop your balls from shrinking btw, it's inevitable when it comes to chronic steroid-usage. Impotence is also very common.
No wonder why you're slinigin cialis down your throat to keep that poor excuse for a dick to get up when the prostitute you're F^@$!ng is ready for it.
The fact that you're on a forum making fun of people only reflects your real broken personality behind the excessive drug usage.  
30 degree dorsal curve, immobility and heavy loss of girth.
My body seems to get very inflamed when I masturbate too often or eat unhealthy.
Using antioxidants, Pentox and hirudoid cream, as well as manual traction, heat and Cialis.

Irishpeyroniecure

Quote from: Godisreal on January 06, 2020, 01:42:41 PM
The funniest thing is, I too have big dreams and my young age is the only thing that holds me in this b*tch of a country. I know stem cells will cure me, doesn't have to be legal. I know that most professionals would take a bribe. Funny how I called them professionals, but they sure know what they're doing. Some of them at least.
The law is to me; a book made to keep the sheep in line. I'm no sheep, but there's nothing wrong with being a sheep - if that's what you want.
You have an attitude that only roid-freaks have, I bet that you're bald too. And when you're on the cycles you feel unstoppable and like nothing can brake you down, right? How about the times when the steroids is going of out your system? You don't feel too good then, do you? You become the b*tch that you really is without your roids.
There's nothing you can do to stop your balls from shrinking btw, it's inevitable when it comes to chronic steroid-usage. Impotence is also very common.
No wonder why you're slinigin cialis down your throat to keep that poor excuse for a dick to get up when the prostitute you're F^@$!ng is ready for it.
The fact that you're on a forum making fun of people only reflects your real broken personality behind the excessive drug usage.

I'm sick with the flu and still have more passion in my posts than any of you though

And I'm on no gear right now

Info is still there though - the things I said work

Best of luck! I mean it! Hope you do well  
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Hawk

IrishPeyroniecure,

You have repeatedly resorted to insults and name-calling.  Consider this your first official warning.  This https://www.peyroniesforum.net/index.php/topic,6.0.html applies to you just like it does the other seventeen thousand members here.  Read and follow if you intend to stay.

Hawk
Founder/Administrator
Prostatectomy 2004, radiation 2009, currently 70 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums