I have been reading about lots of drugs besides the one mentioned in this topic that are currently used for rheumatic disorders and apparently showed benefits for the patients (whose conditions seem to show a pattern similar to the peyronie's one: i.e.
chronic inflammation of soft tissues and fibrotic responses).
This makes me wondering why peyronie's disease is out of the field of rheumatologists. It's a connective tissue disease after all, isn't it? And connective tissue diseases usually fall under the scrutiny of rheumatologists, no matter what the organ involved is. And it looks like these docs' paraphernalia is much more extensive than the urologists' one (at least when it comes to pharmacological treatments).
I know, I'm just rambling but this ramble connects someway to my questions regarding Plaquenil/Hydroxychloroquine: the paper I linked above and others regarding its use for cystic
fibrosis and lung
fibrosis seem to suggest its potential efficacy against scar tissue or, more generally, as an antifibrotic agent. Anyhow, since the drug is an antimalarial and no urologist would even come to think of any benefit from such things for urogenital issues, it doesn't even register for testing in rat-models for peyronie's, while it could be maybe effective and even more than current pharmacological treatments (but who can tell for sure if it's not even being tested).
P.S. it looks like there can be serious side effects by taking this drug (e.g. retinopathy which could also result in permanent vision loss) so I'm not advicing anyone to try it on their own (and, by the way, who would do such things simply based on a ramble of an unknown internet user?

). Nonetheless it could maybe help... If only uros would test more. Instead they are stuck on papers that are decades old (if we talk about the most informed ones that prescribe you
pentox instead of
verapamil) and I am honestly left under the impression that they prefer to live in their own bubble rather than communicating with specialists from different fields and - hopefully - perfecting their approaches for diseases that somewhat transcend their field (like Peyronie's, that - sorry if I repeat myself - is a connective tissue disorders and should be investigated by other specialist too, such as rheumatologists).