ANTIBIOTICS - a contributing factor

Previous topic - Next topic

0 Members and 2 Guests are viewing this topic.

George999

When it comes to antibiotics, I think it is important to remember that an antibiotic alone will NOT give you Peyronie's.  Peyronie's results from MULTIPLE factors.  Antibiotics may be one of them, but it is EXTREMELY UNLIKELY to be the SOLE CAUSE.   I also think it is important to understand that medicine has advanced a lot in the last few decades.  I grew up in a time when if you complained to a physician about burning on urination, they would simply put you on an antibiotic.  As a result I was on multiple antibiotics for years simply because I was experiencing chronic burning on urination.  Then doctors started to actually TEST for infection FIRST.  At that point they found out that I probably never really had very many infections but that it was mostly inflammation, at least during the later years and I haven't needed antibiotics since.  So over the years I was unnecessarily exposed to a huge amount of antibiotics.  And, no doubt, that was a factor related to my contracting Peyronie's,  But there were a host of other factors as well that converged in the process.  In my case it was overweight, high blood sugar, hypertension, lack of exercise, beta-blockers, the list goes on and on.  So remember, antibiotics are just one factor of many.

powderpowder

Do you guys think the general antibiotics like amoxicillan and penicillin cause peyronies? or just cipro and levaquin?

emasculated

We don't know for sure without studies. It's the same with the poison they put into your food, Ractopamine. It's related to Beta Blockers which are now pretty much proven to be contributor to Peyronie's.
"Without health life is not life; it is only a state of languor and suffering - an image of death."

powderpowder

so emasculated....this is all strange crazy coincidence that these guys got peyronies right after taking levaquin and cipro?  and btw guys....do you think normal antibiotics like penicillin or amoxicillin can cause peyronies? because if anything I will take those instead and do research to see what antibiotics theyd give me before nose surgery

LWillisjr

Quote from: powderpowder on August 05, 2014, 03:09:56 PM
Shortly after I had a sexual injury with my girlfriend where I heard the "pop" noise and loss of erection (not a penile fracture but a small trauma) which I then developed Peyronies.

Do you guys think the general antibiotics like amoxicillan and penicillin cause peyronies? or just cipro and levaquin?

I think it was due to the trauma. There are mixed opinions as to whether medications add to or lessen the possibility.
Developed peyronies 2007 - 70 degree dorsal curve
Traction/MEDs/Injections/Surgery 2008 16 years Peyronies free now
My History

NeoV

emasculated,

When I first went in with Peyronie's problems at age 18 I was put on cipro and beta blockers. What a joke!!!!!!!!!!!!!!!!
Totally feel your pain man, we have the right to be outraged.

MikeSmith0

Wow - my 4 year old thread is still somewhat active... well.. . sadly, no research has been done though I have spoken with a few epidemiologists.  Not many people have access to the data that would be needed to do a study on this.

Btw - there is virtually no reason to ever take quinolones & they have many more side effects than tendon damage.  Doctors got lazy and overused them, rather than learning the list of 40 cephalosporins or tetracyclines.  Every doctor just wants to write a RX for cipro...but doxycycline or cefprozil or augmentin - can call cure the same exact infections if the MD would bother to spend another 10 seconds thinking.  I just say I'm allergic to quinolones and magically I get a totally different antibiotic from another class that cures whatever issue I've had.  

Head Up

Now that I think about it, about a month before I developed Peyronies Disease in 1/2013, I had been on antibiotics the month before. Don't remember which one, but it was brief, maybe a 10-15 day supply. I'm going to hunt down my Uro and see what he prescribed me back in 12/2012 and I'll report back here.

perico1974

I have been taking ciprofloxacin over a month for a prostatitis, and develop Peyronie.
finally resulted inflammatory prostatitis and not an infection.
Beware of the cipro

dupuy

I just start to get some symptoms of Peyronie one month after a one week course of Levaquin.  At the same time I got a start of Dupuytren on my hand.  I also think the levaquin could have been the trigger.  A question for the people who are in the same case: what was the evolution of the disease after you stopped taking the medicine, did it eventually got better?

Jim Cyb

I had a horrible reaction to Cipro 3 months ago, and just recently developed what I believe to be Peyronies, I dont have a diagnosis yet but suddenly my erect penis is curved. I do not recall a trauma of any kind. When I learned that Peyronies might be what is causing the sudden curvature, immediately I suspected Cipro as the cause as I have had so many problems in the past 3 months, muscle/tendon issues, peripheral neuropathy, brain-fog etc. This forum thread was the first result that google showed me when searching for a connection between Peyronies and Fluoroquinolones. I believe Fluoroquinolones to be absolutely poisonous to a (large) minority, there are several groups on social media with many thousands of members adversely affected by these drugs. Whenever I think this crap cant get any worse it just gets worse, Cipro is the gift that keeps on giving.

james1947

I am also sure that antibiotic I was taking before Peyronies was a contributing factor, but had other factors more heavy on the scale.
Proposing to read Gorge999 post « Reply #51 on: July 27, 2014, 01:15:07 AM » on this topic

James
Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe ED.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

Juan

I've just started (just two days in) a round of 14 days of cipro for a bacterial prostatitis (enterococcus faecalis showed up in a semen culture)
Just find this post and I'm freaking out.
I already have peyronies but I'm really scared it can worsen due to cipro.

Don't know what to do. I have prescription for other antibiotic called Nitrofurantoin.

If I stop now after only 2 days do you think there is still risk of future damage?

39 yo. Onset Oct/20. 25º dorsal bend 1cm before glans + high erection angle.
Pentoxifiline 400x3. Tadalafil 2,5. Vit E, D3, K2. Zinc.Omega3. Ubiquinol. ALCAR.
Traction with PMP.

Asphyxia

You can eat yogurts, kefir and other fermented foods but you need ones with live active bacteria, i ferment yogurt, water kefir and vegetables at home its not too hard
Age:23. Onset of symptoms: september 2020.
Curve mostly semi erect about 60 degrees, slight pain
Tried short & prolonged fasts, keto,carnivore, traction and most of the supplements.
Severe digestive issues, probably an autoimmune disorder

Juan

Quote from: Juan on December 18, 2021, 06:00:59 PM
I've just started (just two days in) a round of 14 days of cipro for a bacterial prostatitis (enterococcus faecalis showed up in a semen culture)
Just find this post and I'm freaking out.
I already have peyronies but I'm really scared it can worsen due to cipro.

Don't know what to do. I have prescription for other antibiotic called Nitrofurantoin.

If I stop now after only 2 days do you think there is still risk of future damage?

Just for the records,
I had to stop cipro after only 4 pills due to side effects (pain in both knees ans achiles). I've been floxed by cipro. One new thing I've learnt...new Reddit comunity joined etc...more weight for my backpack

I'm 5 days out of cipro and my both achiles tendons are better but still hurt and feel tired, weak...

IMPORTANT: pain in erection state during nte has returned.

I don't blame myself for taking this crap. I knew the pros and cons. Knew the odds. Talked with up to 4 uros, 1 general practitioner, 3 pharmacists...all of them told me I had to take it due to infection and it was very very rare to experience the severe side effects. I was desperated after more than 3 months suffering perineal pain, HF and burn in the tip of urethra after ejaculating and coccyx pain which could be related to all the mesh in that area....so I accepted taking it.

Now I'm with amoxicillin.

What can I do now in regard of my peyronies? Avoid sex/masturbation? Till when...there is no way to know when you are out of danger (even we don't even know if there is actually a real connection between cipro-peyronies)
The die is cast
39 yo. Onset Oct/20. 25º dorsal bend 1cm before glans + high erection angle.
Pentoxifiline 400x3. Tadalafil 2,5. Vit E, D3, K2. Zinc.Omega3. Ubiquinol. ALCAR.
Traction with PMP.

Asphyxia

I think most of the danger after taking an antiobiotic is developing SIBO and/or candida overgrowth, which can trigger autoimmune symptoms.
im having a surgery soon and they will give me antibotic while im under anesthesia, im planning to take natural anti-bacterial supplements and mct oil after that to attempt avoiding that overgrowth risks and repopulate the gut after that with fermented foods all while following a diet low in FODMAP and low glycemic index carbohydrates, or maybe no carbs for a short while except for certain vegetables and maybe some berries.
And then start adding the prebiotics
Age:23. Onset of symptoms: september 2020.
Curve mostly semi erect about 60 degrees, slight pain
Tried short & prolonged fasts, keto,carnivore, traction and most of the supplements.
Severe digestive issues, probably an autoimmune disorder

Christopher1

I never write for fluoroquinolones. Read too many horror stories.
Snake Diet + 5-day fasts + pentox + NeoV's stretching routine + Mito Red Light. Curvature 99% gone.

I also used Todd Capistrant's "Fascial Distortion Model" to help my curvature. Start slowly.

bentoboy

Hi there,

I think I have the same problem as you do.

In 2020, I had a long-term penile inflammation which was really hard to treat. I visited tens of different doctors trying to find out what the problem was, and there were different diagnosis like staphyloccocus infection, STI or lichen sclerosus. While none of these confirmed, I was prescribed a ridiculous amount of antibiotics.

That is to say, circumcision really helped the penile inflammation I had but then I was taking lots of antibiotics before and after the surgery. I also took Tricaside for trichomoniasis (for about 10 days, it was horrible : no appetite, sick and stomach issues) and later levoflaxacin (for 10 days as well). Then I developed Peyronies a few months after.

The bizarre thing is that it was in 2020 but now it's 2022 and I'm still developing Peyrony plaques. I think my problem must be related to this overuse of antibiotics, I've found no other expalanation - I'm quite healthy otherwise (million blood and other tests confirm).

It seems I have also developed some kind of an autoimmune disease because of all this. I assume that my long-term inflammation and the excessive use of medication had caused an autoimmune disease which, in its turn, caused Peyronies - perhaps.

Do you think there is a way to 'reset' the body after long-term use of antibiotics? I was planning to buy some probiotics but don't think it's going to help in any way. Perhaps I should do fasting or change my diet? Asssuming there's a DNA damaged caused by excessive use of antibiotics, do you think it will stay this way forever or there have been cases when it returned to normal?


Also, those people who are good at chemistry might be interested in this article: https://www.hindawi.com/journals/omcl/2017/8023935/
Quote
(a)Long-lasting OS destroys the mitochondrial DNA and the newly synthesized proteins creating cytochrome complexes are disturbed in their structure leading to permanent electron leakage and OS.(b)The complexes of FQ with proteins and cations are so stabile that they exist in the cells by many years disturbing energy production and epigenetics.(c)Epigenetic changes in gene regulation become persistent many years of FQ application even in the case of lack of FQ in the cell.
27 y. o. Peyronies since 2020: S curvature with the top part tilting to the left - 15*. Multiple nodules and scarring on each side, mild hourglassing. Getting worse every few months, losing width. Normal penile function. Enlarged veins.