PAV cocktail question

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samsung

If you don't currently have much erectile dysfunction do you need the (cialis, levitra, etc.) part of the cocktail? I understand it is intended to speed healing through increased bloodflow and all that, but I don't want the side effects of cialis. Don't want to take it if I don't have to.
45 y.o. Single. Onset of symptoms (pain-stinging like a wasp) @ 6/2018. No sudden injury. Curve developed slowly. 40 deg. dorsal. Hourglassing. Torsion to left flaccid. 4 rounds xiaflex. Restorex, DMSO+, heat, arginine, cialis, lipoic acid, vit. K2

Bubba dawg

Increased blood flow won't get rid of Plaque. Just helps you get an erection if you have ED or a better erection if you have Peyrones. IMO
5 Rounds of Xiaflex. Good results.

I am known to give out false information and post nonsense with little to no evidence to back up my claims.
I have ignored several warnings. Further reports to the moderators or Administrators and I will be banned.

Christopher1

Correct.

Nightly viagra or cialis is recommended for increased nocturnal blood flow for healing. This is per my urologist (Dr. Carrion in Tampa, FL).
Snake Diet + 5-day fasts + pentox + NeoV's stretching routine + Mito Red Light. Curvature 99% gone.

I also used Todd Capistrant's "Fascial Distortion Model" to help my curvature. Start slowly.

TonySa

I believe studies do show decreased plaque w nightly low dose PDE5I (whatever due to such as increased blood flow).  Maybe try generic viagra if the cialis has side effects.  What dose are you taking?
PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

Hawk

BubbaDawg's post is incorrect.  Increased Oxygen does help reduce plaque.  In fact plaque often follows the loss of night-time erections. So any erections day or night contribute to healing plaque because they carry oxygen-rich blood.  There may be other contributions to healing by adding the PDE5 inhibitor to the cocktail that has not been fully identified.  It could increase residual oxygenating blood flow even without an erection or possibly affect some other mechanism for combating plaque.

I am not saying you will not get any benefit without it but most Peyronies Disease specialists would recommend it even if you don't have Erectile Dysfunction.

The daily Cialis seldom causes side-effects
Prostatectomy 2004, radiation 2009, currently 70 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums

Bubba dawg

I wish it were that easy Hawk. Is so it wouldnt take injecting Xiaflex right into the plaque. Even that doesnt work sometimes.  We could all just take a pill like viagra and cialis instead of painful injections . That is really just your opinion right? Funny about studies. Studies show Xiaflex works. Many come on here and say it did not work for them. So just because you get a positive study doesnt mean it's a fact for everyone. Some could be just wasting their money. Cialis is expensive. Viagra generic is  close to $400 for 12 100mg pills.
Studies show that Chemo works for cancer. Many chemo patients die within a year while on Chemo
People post some crazy things on here. You ignore those. I post that an erection pill won't get rid of plaque. For most people it wont. I am taking viagra. Hasn't done anything for my plaque. Dick hasn't changed shape. I do get a boner though. Members are looking for an easy way out instead of xiaflex, surgery, hours of traction daily. Ya just pop a pill. My doctor never said here's a pill... I was hoping for that lol
Just my opinion! Based on some studies somewhere. I have read a bunch about treatments, concerning meds and supplements. A study showed this is effective. Another study showed it had no effect. Doesnt stop people wasting their money hoping the first study is the right one  
5 Rounds of Xiaflex. Good results.

I am known to give out false information and post nonsense with little to no evidence to back up my claims.
I have ignored several warnings. Further reports to the moderators or Administrators and I will be banned.

Hawk

BubbaDawg, you have to read carefully and follow the conversation.  You then have to write just as carefully when you post.  At NO point did I ever even suggest that the PAV cocktail is a certain cure for Peyronies Disease AND at NO point was that question even asked.

1. The question was asked if you need to include a PDE5 inhibitor like Cialis with the PAV cocktail if you don't have Erectile Dysfunction.

The answer is YES since the theory for why the PAV cocktail works (as it surely does for some men) is based on increasing nocturnal erections and increasing residual blood flow between erections.  It is also thought to possibly interfere with other psychological processes that cause plaque formation.  Lack of oxygenated blood alone is known to be associated with plaque development.

In fact the L-Arginine in the PAV cocktail is also for the express purpose of relaxing arteries and increasing blood flow.

No one ever asked if the PAV cocktail is a certain cure or what percentage of men respond to it or what degree of response various men get from using it.  There was no discussion about comparing it to any other treatment EXCEPT comparing it to the PAV cocktail without a PDE5 inhibitor in men without Erectile Dysfunction.  You then jumped in and provided completely false information to a man looking for an answer on that question.  

I had an obligation to correct that misinformation for the thousands of men that will read that post and possibly be more misguided because of it.
Prostatectomy 2004, radiation 2009, currently 70 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums

samsung

Thank you Hawk. And thank you for your PMs as well.
45 y.o. Single. Onset of symptoms (pain-stinging like a wasp) @ 6/2018. No sudden injury. Curve developed slowly. 40 deg. dorsal. Hourglassing. Torsion to left flaccid. 4 rounds xiaflex. Restorex, DMSO+, heat, arginine, cialis, lipoic acid, vit. K2

Bubba dawg

5 Rounds of Xiaflex. Good results.

I am known to give out false information and post nonsense with little to no evidence to back up my claims.
I have ignored several warnings. Further reports to the moderators or Administrators and I will be banned.

Christopher1

If the viagra or cialis is too expensive, just get it from alldaychemist.

Works fine.
Snake Diet + 5-day fasts + pentox + NeoV's stretching routine + Mito Red Light. Curvature 99% gone.

I also used Todd Capistrant's "Fascial Distortion Model" to help my curvature. Start slowly.

TonySa

Generic viagra, 100 mg is now available for pennies.  Check out good Rx dot com for prices in your area. Today's prices in SF. Just get a pill cutter and cut them in 1/2 or 1/4.
PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

Bubba dawg

Tony my Viagra pills couldn't not be cut up. If there is no line then there is no even distribution according the the Pharmacist. If you cut it in half then you may get no medicine in one half. i am sure somebody will chime in and say I am lying lol  
5 Rounds of Xiaflex. Good results.

I am known to give out false information and post nonsense with little to no evidence to back up my claims.
I have ignored several warnings. Further reports to the moderators or Administrators and I will be banned.

Hawk

BubbaDawg brings up an interesting point. It is generally true that there is no guarantee of even distribution of medication in some medications and Viagra is one of those.  No doubt that is to for the express purpose of charging more for a smaller dose pill than for a cut larger dose pill.  I think, but have no proof that the likelihood you would get all the drug in one half of the pill is beyond unlikely.  If you cut a pill in quarters I think some quarters could have significantly more drug in them than other quarters. I am sure they would all have a quantity of the drug in them, however.  

If this were heart medication it would be a VERY bad idea.
If you are depending on the dose for the precise amount of drug needed for an erection to have sex with a hot date it would be a somewhat poor idea
If you are trying to get some of the drug daily as part of a cocktail of drugs that synergistically work together I think it is probably an OK idea.  Some days you may get a little more, some days a little less, no big deal since the blood optimal levels of the drug are not precisely known anyway.

In reality, I have had some people suggest that "not mixed evenly" caution is a gimmick to get you to buy a larger quantity of the smaller dose pills at a greater profit to the company and the difference from one part of the pill to another is negligible.  It would be interesting to find more evidence on this point.
Prostatectomy 2004, radiation 2009, currently 70 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums

Bubba dawg

Ya the Pharmacist said if there is no line in any pill then it is not evenly distributed. I cut it anyway 4 ways. I was unhappy with the results. Sometime in the night I got one erection. Past due. I took a whole 100 mg one and got erections from 7 pm to 3 am off and on. I would say your best bet is to cut it in half and take your chances. Still would be expensive to take every day like that
5 Rounds of Xiaflex. Good results.

I am known to give out false information and post nonsense with little to no evidence to back up my claims.
I have ignored several warnings. Further reports to the moderators or Administrators and I will be banned.

TonySa

Viagra is now very inexpensive.  Go to goodrx dot com to find the best prices in your area.
PxD 2 yrs 9/16.  Failed all treatment. 9/11/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3-1cm RTEs.
Pump failed.  2/11/20 Dr Karpman installed Titan 22cm +1cm RTE.

Bubba dawg

5 Rounds of Xiaflex. Good results.

I am known to give out false information and post nonsense with little to no evidence to back up my claims.
I have ignored several warnings. Further reports to the moderators or Administrators and I will be banned.

jake xyz

get your Dr. to prescribe the 20mg generic Sildenafil (Viagra).  With Good Rx, I was able to get 90 pills for $32 at Costco.  But my refill was $62.  The price fluctuates so you can use Good Rx to see where is the cheapest at the moment.  The best I could do with the 20mg Cialis was $150 for 6 pills.  Lucky for me, Cialis made me feel terrible.

With the 20mg pills, there is no need for cutting and it gives you a variety of easy dosing.
M-56, ED from RALP on May 14, 2018.  PSA 0 currently. Tried Viagra (kind of works), Trimix & Edex.

Hawk

Good information Jake.  I knew of this generic Viagra but right after it appeared some physicians were hesitant to write scripts for it off label for ED since somehow Pfizer apparently held onto the rights to Viagra (sildenafil citrate) at 50mg & 100mg for ED but it went generic for pulmonary hypertension in 20 mg.  I do not fully understand those details.  I have never seen the same formula go generic for one use and not another.  It is kind of weird.  No doubt a way for Pfizer to squeeze out a few more dollars before it loses it totally.

If you can get a physician to write a prescription off-label for the generic it is clearly the way to go.
Prostatectomy 2004, radiation 2009, currently 70 yrs old
After pills, injections, VED - Dr Eid, Titan 22cm implant 8/7/18
Hawk - Updated 10/27/18 - Peyronies Society Forums