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Author Topic: Antidepressants and Peyronie's Disease  (Read 402 times)

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Worried89

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Antidepressants and Peyronie's Disease
« on: June 06, 2019, 06:45:33 PM »

I've scoured this forum for threads on SSRIs and any possible connections to Peyronie's Disease, but as expected I found no definitive answers and wildly different anecdotes. After three years of delaying medical treatment for my OCD and Depression due to fear of its sexual side effects or any other side effects exacerbating my Peyronie's, I've reached a point where my quality of life has deteriorated such that I need something to take the edge off; after consulting with a very well respected psychiatrist, he recommended Fluvoxamine (Luvox) beginning with 50 mg.

It's been years since I've taken any SSRIs; the last time was two years before Peyronies Disease manifested, and I have no reason to connect the two. However, I'd like anyone with any intel on this to help me acquire any information on whether Fluvoxamine, or SSRIs in general can indeed make Peyronies Disease worse, or if I have nothing to worry about provided that I can still get healthy erections regularly.

Edit: Also, I heard that SSRIs can raise blood sugar. Might this not also increase the risk of exacerbating Peyronie’s?

Thanks in advance for any and all help.
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Worried89

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Re: Antidepressants and Peyronie's Disease
« Reply #1 on: June 26, 2019, 07:08:07 PM »

I hate to bump this, but I'd really appreciate some info before I put myself on an SSRI and risk any further worsening of my Peyronies Disease. Thanks.
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TonySa

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Re: Antidepressants and Peyronie's Disease
« Reply #2 on: June 27, 2019, 03:52:30 PM »

Def give it a try!  If it gives you any sexual side effects then work w your doc.  (Sometimes causes delayed orgasm.). You may also want to ask about Wellbutrin.  Usually much less sexual side effects and available as generic.
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PxD 2 yrs, failed all tx. 9/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3rte

Worried89

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Re: Antidepressants and Peyronie's Disease
« Reply #3 on: June 28, 2019, 05:30:54 PM »

I don't just want to try it without any info. Are there any studies about this matter? Is it the SSRI itself that can trigger Peyronies Disease activation, or is it the risk of it developing from the medication's sexual side effects?
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TonySa

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Re: Antidepressants and Peyronie's Disease
« Reply #4 on: June 28, 2019, 05:55:20 PM »

It doesn’t trigger peyronies.
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PxD 2 yrs, failed all tx. 9/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3rte

Worried89

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Re: Antidepressants and Peyronie's Disease
« Reply #5 on: June 28, 2019, 07:21:31 PM »

Do you have any resources or studies you can link? Or discussions? You have no idea how worried I am about starting Luvox. I'm going out of my mind.
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TonySa

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Re: Antidepressants and Peyronie's Disease
« Reply #6 on: June 28, 2019, 07:46:48 PM »

That’s the point, no studies indicate it causes peyronies.  I think it’s your anxiety immobilizing you.  Counseling can also help, especially cognitive behavioral therapy.
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PxD 2 yrs, failed all tx. 9/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3rte

Christopher1

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Re: Antidepressants and Peyronie's Disease
« Reply #7 on: June 29, 2019, 12:27:10 AM »

SSRIs are well known to cause sexual dysfunction (i.e. Erectile Dysfunction).

SSRIs --> increase serotonin --> serotonin has been correlated to fibrosis. Peyronies Disease is fibrosis.

It's possible. No evidence on it though. Decent hypothesis.
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Snake Diet + 5-day fasts + NeoV's stretching routine. Curvature 99% gone. Still have bothersome scar pain. Please message me for a good Peyronies Disease pain cure.

Big benefits experienced from a 2-month NoFap "flatline" (read about flatline) + Kegels

TonySa

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Re: Antidepressants and Peyronie's Disease
« Reply #8 on: June 29, 2019, 03:13:25 PM »

Not really, so MANY men have taken antidepressants for years, we would have heard something by now.
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PxD 2 yrs, failed all tx. 9/18: excision, grafting & implant Dr Karpman MtnView Ca, AMS CX 18cm + 3rte
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