0 Members and 1 Guest are viewing this topic.
Quote from: George999 on April 06, 2011, 11:04:27 AMFor the past week I have been using a product called Stabilium 200 which is marketed as a solution for anxiety. Years ago I took Klonopin/Clonazepam for anxiety and never have found anything as effective since. But Klonopin is essentially a controlled substance and getting a doc to prescribe it is nearly impossible. They much prefer Xanax or Valium, neither of which were helpful for me. Things like Valerian did the job, but nowhere to the degree of Klonopin. But now I have found something, which seems to actually be *better* than Klonopin. Stabilium 200 immediately lowered my blood pressure significantly, which for me is a marker of significantly decreased anxiety. It also has improved my sleep noticeably. As such, it might be worth a shot if you have anxiety issues with Pentoxifylline. ADDITIONALLY, I believe that anxiety and stress aggravate Peyronie's directly, so it might help in more ways than one. A very concise description of what this substance is can be found on ehow.com for those of you who might be interested. - George
Quote from: George999 on April 08, 2011, 09:16:34 PMI haven't noted any side effects at this point. What really surprised me is not seeing a BP spike when I ate salty food at a memorial service. This is pretty unusual for me since salty food always pushes up my BP. I have also been using Valerian Nightime again and Bio-active Milk Peptides. But I think it is the Stabilium that is really doing the trick for me. It may be available for a lower price than iHerb, all I know is that iHerb's price is less than LEFs. Actually it looks like this place has it on sale right now. And here is another low cost vendor. - George
Quotepentoxifylline (PTX), a PDE 1-5 inhibitor
Quote from: lwillisjr on April 19, 2011, 11:01:06 PMThanks,Another reason why I like this forum. Constantly learning something new.
Quote from: Woodman on November 15, 2011, 01:27:43 AMI was searching to find out if Pentox "Trental" is a immune suppressant. I cannot find the ansewer and was wondering if anyone knew if it is or isn't. I ve been taking Trental again for about one month now and noticed in that time I ve got Jock itch, Athletes foot & now a sore throat. Usually if I get jock itch and or athletes foot I can just treat it with OTC medicine and it will go away. Now I ve tryed all the OTC stuff and can't seem to shake it. Treatal is the only real medicine I am taking besides omeprazole witch I ve been taking for years for reflux. The only other things are just supplements L Arginine, CoQ10, fish oil & vitamin D. I also take a generic Clariton for allergies.Any input would be great.
Quote from: George999 on November 15, 2011, 10:55:37 AM... Pentox IS a mild immune suppressant. It can cause an abnormally low white cell count and it can exacerbate any type of infectious disease. It is advised that when one is fighting an infection of any kind, one should briefly stop Pentox to allow the infection to clear up and then restart Pentox.
Quote from: George999 in another strand on December 03, 2011, 01:15:42 AMYou have to remember that Dr Lue's primary theory regarding Peyronie's is that it is driven, at least in part, by the cytokine TGF-beta1. And that theory is supported by a significant amount of research. Pentoxifylline blocks TGF-beta1.
Quote from: ppain on December 03, 2011, 11:59:09 PMSmith was Lue's student. Lue is behind the 2011 paper (and listed as the 8th and last author). Interestingly the 2011 paper reverts to the older understanding of Pentox for explaining its efficacy at reducing Peyronie's calcification.
Quote from: Luciano on December 04, 2011, 07:46:34 AMQuote from: ppain on December 03, 2011, 11:59:09 PMBut what I am trying to say is, that we cannot be sure that Dr. Lue is behind this publication, he might only have signed in as coauthor, because he was asked to by his students and principly agrees with the publication.NOTE: i said: "might" have signed in.. not has signed in.LucWhile this is possible, also note that Dr. Shindle, who is one of Dr. Lue's colleagues, signed on as well. Rather than racking up points, I believe they are one of the few urology groups trying to publish research on the disease. I'm only speculating here, but I imagine that it's tough to get a large Peyronie's drug study together because pentox is so dirt cheap, i.e. the large drug companies have little financial incentive to support or encourage such research. Therefore I believe that Dr. Lue and the others are carrying out such research to further understanding of the disease and encourage more research that could piggyback on what little research already exists. Just my 2 cents.Skjaldborg
Quote from: ppain on December 03, 2011, 11:59:09 PMBut what I am trying to say is, that we cannot be sure that Dr. Lue is behind this publication, he might only have signed in as coauthor, because he was asked to by his students and principly agrees with the publication.NOTE: i said: "might" have signed in.. not has signed in.Luc