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Author Topic: PENTOX - Side effects  (Read 99049 times)

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Litani

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Re: PENTOX - Side effects
« Reply #350 on: April 08, 2014, 04:05:32 PM »

I drink Citrucel every morning and evening.  It helps me to continue Pentox.
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Skjaldborg

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Re: PENTOX - Side effects
« Reply #351 on: April 08, 2014, 04:17:22 PM »

I took pentox in my early 30's and constipation was never the problem. The opposite was more likely to be true.

-Skjald
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james1947

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Re: PENTOX - Side effects
« Reply #352 on: April 08, 2014, 09:22:21 PM »

My answer is similar to Skjaldborg answer. In my case the opposite was clearly true.

James
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Leitmotiv

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Re: PENTOX - Side effects
« Reply #353 on: January 06, 2015, 04:37:15 AM »

Hello everyone!

I started taking Pentox today -  I couldn't wait to see a new doctor, so I stared by myself.

Here they sell Pentox 600 mg/pill.

I decided to begin with one pill/morning as per James 1947 for 1-2 weeks, and then start taking 2/day.
I took the pill 4 hours ago, at breakfast. Not sure whether it's the pill, or the fact that I read a lot of things about side effects, but after I took it I started feeling a little dizzy, slow thinking/reaction. But in comparison with what other ppl describe, this side effect isn't that bad. Also a bit of a stomach high acid.

Anyone else experienced this?

Also how about smoking and drinking while on Pentox, as well as gym(bodibuilding exercises)?
I am social smoker (maximum 10 cigarettes/week), also I sometimes drink 1-2 times/week I can have 3-4 glasses of wine.
Thanks!
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Jonbinspain

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Re: PENTOX - Side effects
« Reply #354 on: January 06, 2015, 03:59:21 PM »

There are, unfortunately, numerous side effects associated with Pentox. Personally, I found Pentox and alcohol not to be a good idea, it made me very sleepy and tired. Also, make sure you take it with food, Pentox on an empty stomach is not a good idea.

As I don't smoke, I can't comment on that.
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Talons4444

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Re: PENTOX - Side effects
« Reply #355 on: January 06, 2015, 04:21:04 PM »

Sounds like everyone is different on the side effects. I have not had any side effects at all. Also not sure it is doing anything at all. I have not noticed any difference and I guess I hope that it will prevent things from getting worse.
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james1947

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Re: PENTOX - Side effects
« Reply #356 on: January 06, 2015, 06:16:28 PM »

Leitmotiv
Good luck with the Pentox.

Talons
Pentox may help to arrest the disease. Regarding differences, you should have a blood test before starting Pentox and after 3 months lets say. What is the quantity you are taking?

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
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KAC

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Re: PENTOX - Side effects
« Reply #357 on: January 06, 2015, 09:39:48 PM »

I was dizzy the first week when I started Pentox.  Driving was not a great idea--I was pretty lightheaded a few times.  After the first week, I was fine.  I've not noticed any other side effects other than general anxiety that may or may not be related.  I always take it with food. Haven't noticed any difference with alcohol.
KAC
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Leitmotiv

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Re: PENTOX - Side effects
« Reply #358 on: January 07, 2015, 05:19:15 AM »

James what blood test are you reffering to? What should we measure?
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james1947

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Re: PENTOX - Side effects
« Reply #359 on: January 07, 2015, 07:09:29 PM »

Blood pressure, Platelets, white blood cells, red blood cells.

James
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Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
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Jonbinspain

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Re: PENTOX - Side effects
« Reply #360 on: January 08, 2015, 01:53:36 AM »

Leitmotiv;

I think what James is trying to get across is that Pentox can weaken your immune system. Therefore, a periodical blood test will determine if that has happened in your case.

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james1947

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Re: PENTOX - Side effects
« Reply #361 on: January 08, 2015, 05:49:01 AM »

You are right Jonbinspain :)
I was hoping it will happen to me, I mean to lower my blood counts as my "normal platelets" are 1,000,000 and the "normal" white blood cells on 20,000+, but it not happened. Still after 18 months I was getting severe flue every month. Stopped Pentox, Flue stopped :)

James
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Leitmotiv

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Re: PENTOX - Side effects
« Reply #362 on: January 09, 2015, 04:57:14 PM »

Today I decided to double it and I took 1200 mg instead of 600.
No dizziness, no stomach pain or anything, just for a few seconds I had (which is strange)my heart beating very fast.
If I don't get side effects at the beginning this means they cannot appear later, or they usually appear later?

James, after 18 months of use, how did your plaque/curvature improved?
Thanks
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james1947

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Re: PENTOX - Side effects
« Reply #363 on: January 09, 2015, 06:18:33 PM »

Leitmotiv

Good luck with the 1,200 mg. :)
Good chance (but nor sure) if you don't have side effects now, you will not have in the future, except again the immune system weakening that can occur.
I can say that after more than 2 years on VED, Cialis and 18 months Pentox, the calcified plaques were softened an the 3 hourglasses disappeared. Little better erections, the left bent less, up curve same. Gained back some lost length and girth.

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
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Leitmotiv

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Re: PENTOX - Side effects
« Reply #364 on: January 17, 2015, 09:07:36 AM »

After 8 days on 1200 mg Pentox I can say that I have no side effect. Not even my stomach, because I take the pills with food, as per your advice.

I take the pills like this : 1 at breakfast at about 9 in the morning, the second one at lunch (14:00-14:30).
This is because my pills are 600 mg (this is what they sell in Romania). Do I take the pills too close one from another?

Also, I was thinking to raise the dose up to 1800 mg (3 pills a day). Will this have a stronger healing effect?
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james1947

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Re: PENTOX - Side effects
« Reply #365 on: January 17, 2015, 05:06:28 PM »

Some forum members got prescription for 2400 mg per day from leading Peyronies specialists because they think higher dosage have stronger healing effect.
You may increase the intake to 1800 if you wish and see what happening from the side effects point of view.
Keep in mind that Pentox, VED, low dose Cialis and basically all the oral and mechanical treatments are a marathon and not sprint.
I also thing that you may eat your breakfast earlier, same your lunch and have dinner at 6 PM. If you don't have any side effects, maybe 7 or 8. For me, latter than 6 makes problems.

James

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artguy1

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Re: PENTOX - Side effects
« Reply #366 on: May 08, 2015, 07:00:40 PM »

Question:   Over what period of time is Pentox usually taken?   Months?   Years?    I'm only on my third week of Pentox and have been experiencing a lot of tiredness with no change in my daily activities -- excepting I really have to push to get anything done.    By mid-morning I feel like I could go back to bed already.    Also, I'm experiencing depression.     I'm willing to put up with both the tiredness and depression if the Pentox improves the Peyronie's condition.   Just wondering how long some of you guys have been taking it.  I won't see the urologist for another two months. --artguy1   
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LWillisjr

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Re: PENTOX - Side effects
« Reply #367 on: May 09, 2015, 09:54:49 AM »

I was on it for 6 months. Didn't have any side effects, but also no improvement so my doctor took me off it as we proceeded with surgery as a course of action.
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wonderbread1662

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Re: PENTOX - Side effects
« Reply #368 on: May 10, 2015, 04:00:07 AM »

My experience with pentox overall has been positive. I started pentox about 3 to 4 weeks ago and in the first 3 days of taking it I had many side effects. I found my appetite to be gone and when I would force my self to eat I would get nauseous. I also noticed that it felt like I had something small stuck in the back of my throat when I swallowed. Almost like the pill got stuck in my throat. I found out that I was allergic to pentox and that it was swelling up my throat. I now take benadryl 3x a day 25 mg with my pentox.

I only take 1 at a time as 2 is bit much and it feels like I am being put to sleep. Benadryl solved my allergic reaction but then I started to get constipated. I also at times now have heartburn from time to time which has never happend till I was on pentox. I have trouble sleeping as pentox has given me insomnia. When I do sleep I do get very vivid and real dreams now which is kind of cool. I never used to get many dreams until pentox.

The worst part of my side effects is I felt my arms and legs get very tingly. It kind of felt like they were asleep and they felt achy and weak. I found that massaging and vibration helped with this. I bought a back massager online and I used that for a while. The tingles have gone away for the most part. I had that for about a week. You should never take pentox without a meal. I have very reduced side effects (if any) if I eat half my meal and then take pentox. Then I finish my meal and the only side effects I have now are constipation, heartburn (sometimes), and insomnia. Pentox has caused me to go through hell for the first 2 weeks but then my body got used to it. With in the first week pentox has taken away most of my flaccid and erect pain along with almost no inflammation.

In my opinion pentox has been worth it. The things we do for a healthy penis. Oh and I also got enlarged veins in my feet that hurt to move my feet or to put pressure on them. That comes around every now and then but went away for the most part.
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GuitarHero

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Re: PENTOX - Side effects
« Reply #369 on: June 03, 2015, 12:59:25 PM »

Is there anybody else around here who seem to be super-sensitive to Pentox? I've tried it on few occasions in the past to treat Peyronies Disease, but every time I have quit after a week or two as the side effects just get too damn strong.

What's most weird, is how low dosage is enough to causes this.

I've always started with 1/2 pill, meaning 200mg /day. Single dose. In few days this makes me feel warm and penis feels fuller while flaccid, soon after erections feel stronger too, like a mild Cialis effect. After a week or so, I start to feel HOT all the time, I sweat like a pig even walking outside when it's cold rainy day, or just sitting in a bus.  The worst of all is the flushing, I get red all over like a crab.

I've tried 1 pill / 400mg a day, but with this dose these side effects get just simply unbearable and also after a week or two my stomach usually gets broken, and I get nausea, diarrhea, heartburn and all the other great stuff. On top of that, I get very vivid and scary dreams all night long and I feel nervous.

Now I've always wondered, would it be worth it to try just stick with the 200mg a day or even lower than that - is there any point? Does it mean if I'm sensitive to sides, I could also be sensitive to the drug it self and therefore the low dose would do it's job?  More receptors for this drug on my body or something like that perhaps..?

You guys who have experienced similar side effects, do these get easier by time if I'd just try it with low low dose for a longer time, or does it get just worse with pentox?
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james1947

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Re: PENTOX - Side effects
« Reply #370 on: June 03, 2015, 07:38:46 PM »

GuitarHero

It is written very clear on the Pentox pack, do not broke or chew the pill so taking half pill is wrong.
Also are you sure you got the slow release? The regular ones, may have the symptoms you are describing, I had them as my first one month supply was not the slow release.
Take on 400 mg in the morning always with meal. I done it for two weeks until my body got used to it.

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
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GuitarHero

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Re: PENTOX - Side effects
« Reply #371 on: June 03, 2015, 08:11:55 PM »

Hi james,

I think where I live in the drug might be different, as this one has a line in the middle to split it in half and they also say in the package that it's allowed.

However about the slow release thing.. I'm actually not sure, but this says "depot capsule" so I suppose that means slow release..?

Side effects in my case last all day long anyway, so not sure if it's a matter of release time. Even a day or two after my last pentox pill I will still sweat like crazy and have a red skin.

Did your side effects fade off when you continued for some time, james? What kind of sides you had in the beginning?
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james1947

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Re: PENTOX - Side effects
« Reply #372 on: June 05, 2015, 01:25:11 AM »

I understand.
Regarding side effects, they never faded away completely, but they were very low intensity.

James

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wonderbread1662

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Re: PENTOX - Side effects
« Reply #373 on: June 05, 2015, 12:38:51 PM »

Hey GuitarHero,

I had very bad side effects as well and it did get better after the first week. I ALWAYS eat a full meal with every dose I take. I still get heartburn and very vivid dreams along with insomnia from time to time. I feel that it has helped me though. I don't think that low of a dosage will help much at all in my opinion. It's a good Idea to start off with one a day and work your way up to three. I probably should of done that as I took three right away and totally nuked my body.

Has your skin cleared up after not taking it? If it is the pentox then you most likely are allergic to it like me. With me it swelled up my throat so I take one benadryl with each pentox pill. Most of your side effects should go away after the first week or 2. Once again eating a full meal with pentox helps a lot.

Eat half your meal, then take the pill, and then continue eating your meal. I was lucky in the fact that I was not working at the time. So I was able to stay home while my body adjusted to pentox. I made a post a little ways up if you want more information on how it affected me. I used to get really red and rashy on my face, as well as get all itchy and hot. But that was before I took pentox. Did this just start to happen to you when you were taking pentox? It sounds like an allergic reaction to me but I'm not a doctor. If you decide to try benadryl with it then be warned as it can make you drowsy. So it could be unsafe to drive while using it. For me two benadryl will make me severely tired but one won't effect my energy.
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GuitarHero

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Re: PENTOX - Side effects
« Reply #374 on: June 07, 2015, 07:56:53 AM »

Hi wonderbread,

no this is not actually anything to do with allergy, by red skin I mean flushing. I'm constantly red and if I do anything that makes the heartbeat rise, I will be super red. I think it has to be something to do with the blood viscosity thing that this drug is made for, or something else. They do mention flushing as a common side effect in Pentox instructions after all - but it sucks still and big time.

I have now struggled with 1 pill a day but I'm feeling like in a steam room all the time, even when others are feeling cold.  ::)
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wonderbread1662

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Re: PENTOX - Side effects
« Reply #375 on: June 07, 2015, 12:14:30 PM »

Hello GuitarHero,

Sorry to hear you're having an awful time getting used to the drug. I would give it 2 weeks and see if the side effects get better. If it gets better in 2 weeks then you should try two pills and give it another two weeks. Then on to 3 if your feeling alright. Pentox works really well with cialis 5mg too. It seems to help soften the plaque for some people on here.
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GuitarHero

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Re: PENTOX - Side effects
« Reply #376 on: June 07, 2015, 01:49:00 PM »

Thanks for the support, I'll try to do just that. And if I can't tolerate 2 at least I'm trying to stick with 1 pill a day as long as I can.

I agree, Pentox really seems to be doing something, not yet actually sure what. Cialis and I don't get well so well, it gives better erections for a moment (few days) and after that, it starts to give me harder flaccid and somehow narrower / stiffer (in a bad way, like it would be less elastic) feeling to the penis on both while erected and flaccid, if I take it for longer time. I have never figured why is this, but until I know better I'm trying to avoid it and keep strong erections with other supplements.
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james1947

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Re: PENTOX - Side effects
« Reply #377 on: June 07, 2015, 04:20:13 PM »

10 or 20 mg Cialis makes me flushing, sweat like take a shower, low back pain and no any erection benefits.
The 2.5 or 5 mg, after some 2 weeks of taking it every night have no any side effects anymore.

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
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wonderbread1662

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Re: PENTOX - Side effects
« Reply #378 on: June 08, 2015, 12:13:54 AM »

Hey Guitarhero,

I have not tried cialis 5mg yet, although I plan to shortly. So I can't speak in experience with the drug as I have never taken it. I'm just going off of what I have read from other members that have had positive results with the pentox/cialis combo.

I would again try what James has suggested in that you try it for 2 weeks as he is very experienced with this condition and that particular drug. In the end though it is your penis and if you feel it is doing more harm than good then you should listen to your body. As all our bodies can react to medications differently. That being said, if I were you then I would give cialis 2 weeks to see if it improves your condition.
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Onemorestep

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Re: PENTOX - Side effects
« Reply #379 on: January 04, 2017, 05:51:42 AM »

Hello all,

So originally Pentox seemed wonderful. I didn't notice any negative side effects at first. It actually made me feel quite good. However in the last 7 days a lot of negatives have arisen and they are not typical. It started out with minor irritability that progressed to rage. Ransoms rage and sporadic. Then I seem to have developed some pretty extreme muscle spasticity in my back and rib area. I have nightmares now and wake up sweating. Today I took a nap and woke up feeling suicidal. I had suicidal feelings in the past and am in no way going to be a harm to myself because i understand this is just chemical but still it is absolute doom and despair. It semi faded after an hour.

My dose is 400x3
Today I've been halfing them.

I'm so worried if I stop I'll see rapid progression of my Peyronie's as I've read in some posts. I only developed this a few weeks ago and it's been a nightmare as I'm sure you all know. Any advice would be welcome--although it seems my choice is chance more deformity or chance these emotions and regression into semi permanent depression like I was last year.

Cheers,
Will
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Re: PENTOX - Side effects
« Reply #380 on: January 04, 2017, 06:23:03 AM »

Will, I have never taken Pentox, although I may give it a try as I believe it helps with PAD (Peripheral Artery Disease) which I may suffer from. I have 'stable' peyronie's but don't think Pentox   :-\ will help alleviate my penis curve, manual stretching with warm up is helping with that  :)

Do you take Pentox with food? Food intake shortly before dosing delays absorption of an immediate-release dosage form but does not affect total absorption rate in the body.
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Re: PENTOX - Side effects
« Reply #381 on: January 04, 2017, 07:46:17 PM »

Please don't quote if it is not necessary, moderator

Most pentox is SR or sustained release and you might be getting a sudden excessive release of active ingredient when you break the SR shell and expose the inner tablet to the stomach acid. Instead of halving them I would drop the dose to one in the morning and one at night and see if that helps.  Once symptoms have stabilized then try adding the third tablet back in, but you may only be able to tolerate two tabs if sensitive or do not weigh much.
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Onemorestep

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Re: PENTOX - Side effects
« Reply #382 on: January 05, 2017, 02:33:21 AM »

Thank you for the speedy reply!

You know, I assumed that my issues must have been the Pentox because I thought it was the only new pill I had been taking and it took a day to realize I've never taken acetyl L-carnitive. A little research later and I learned that stuff can really bump up ones acetycholine levels. I already have a very choline dominated brain and anything that raises those levels doesn't sit well. The increases acetylcholine levels accounts for the muscle issues and when combined with increased  norepinephrine the anger makes sense. Since stopping alcar the spasticity has started to resolve and the anger is getting better. Think my brain just needs time to flush the remaining acetylcholine out.

Symptoms currently:
Mild periodic anger/agitation
Mild depression
Can't sleep more than 6 hours (this I suspect is more in line with Pentox)
Physical malaise. Don't feel like moving much.


I will report back on what changes and if things return to how it was when I first started taking Pentox--which is almost no noticeable side effects.

On a positive note I'm sleeping better. Sometimes I'll wake up 3-4 times in a night with the munchies for some reason. Pentox has really helped bring that number down to 1 and sometimes I don't wake up at all. Interesting!

Cheers,
Will
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Onemorestep

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Re: PENTOX - Side effects
« Reply #383 on: February 10, 2017, 11:44:05 PM »

Well I'm back. Been taking the Pentox for about a month and a half now and I have to say I hate the stuff. I've noticed it makes me extremely socially anxious and depressed. It's really screwing with my life. its like I can't relax at all when I'm on it. Really want to stop but worried about the downstairs state. Would hate to have regression. Finding myself taking benzos daily to cope with the side effects. Although they have limited efficacy since Pentox competitively antagonizes benzo receptors.

Any advice? If I were to taper off  how would I do that?

Symptoms:
Anxiety
Loneliness
Isolation
Lack of appetite
Racing heart

Meds
Pentox 400 mg x 3
L arginine 2000mg every other day
Lorazepam 1 mg daily spread out into 2-3 doses
Gabapentin 600mg two doses; one at bed and one 5 hours after sleep
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Paolo

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Re: PENTOX - Side effects
« Reply #384 on: February 11, 2017, 05:45:47 AM »

Hi onemorestep, I am probably going to get shot down here but what the heck!
Have you considered Ginkgo biloba, from what I know, please correct me if I am wrong but Pentox is primarily a blood thinner.

What you are trying to do with Pentox is maximise blood flow to your penis, but to a lesser extent that's what another supplement L-Citrulline Malate does, it lowers blood pressure, L-citrulline is also used to alleviate erectile dysfunction caused by high blood pressure.

If you hate Pentox then suggest you get off it IMHO, unless you know you have claudication  :)

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james1947

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Re: PENTOX - Side effects
« Reply #385 on: February 11, 2017, 07:25:06 AM »

Onemorestep

First Pentox is not a blood thinner in the usual way as aspirin and many others.
Pentox makes the red blood cells flexible so they can penetrate the thinness blood vessels and to provide oxygen to the area.
No any medication/supplement makes that so other blood thinners (including alcoholic beverages :) ) are not a replacement.

I had the same side effects as you are experiencing while started on Pentox. I stopped after 18 months because it affected my immune system.
My proposal to you based on my own experience and many others:
1. Start with one per day (400 mg) until your body get's used to, then increase to 2 and later to 3.
2. Take always with meal.
3. No later than let's say 6 PM (or better 4 hours before you go to the bad).

I tried almost everything proposed on this forum except surgery, Verapamil and Xiaflex, the only treatment that helped me:
Pentox, VED, low dose Cialis.
But it is your body so you may chose what you think it is right for you :)

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
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skunkworks

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Re: PENTOX - Side effects
« Reply #386 on: February 11, 2017, 08:46:10 PM »

Honestly I had zero side effects as long as I took it immediately after a meal. Otherwise, really bad nausea on an empty stomach.
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Onemorestep

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Re: PENTOX - Side effects
« Reply #387 on: February 19, 2017, 05:56:50 PM »

Thank you guys so much for your speedy responses. It's lovely how active this forum is.

I moved the Pentox down to two about ten days ago and just moved it down to one pill a day.

Based on the level of anxiety I was having (extremely high; panic), reluctance to be social, and agoraphobia I was developing I felt I had little choice. It's odd I had no side effects when I first started the drug but they steadily got worse and worse. It was getting hard to explain this to friends.

Another one that's been getting worse is really tight muscles in my back and ribs. This is something that I had chronically for years before treatment with baclofen cleared it up. Since going down to one (this is day two of that) it's gotten better but is still present.

Unfornutately my penis is indeed less full at flaccid. And it feels kinda cold which is a symptom I had before starting Pentox. Hopefully I won't have some sort of crazy rebound with titrating down.

I have tried ginkgo in the past and found it to be enjoyable. I've just been too scared to put anything into my body since I don't know what caused the peyronies since I was taking ginkgo at the time. This disorder is such a crapshoot. Wish it was better understood.

Hope you all are well!
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frank_a_c

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Re: PENTOX - Side effects
« Reply #388 on: February 20, 2017, 01:14:08 PM »

Onemorestep,

I recently went through an identical experience.

It greatly helped me to add in 2grams per day of Acetyl L Carnitine when I went down to one Pentox. I was on pentox for four months with strong side effects and being on one is like re-entering the real world for me.  I recommend this. I also supplement coq10 and l arganine.
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Paolo

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Re: PENTOX - Side effects
« Reply #389 on: February 20, 2017, 02:11:58 PM »

onemorestep, I am currently combining ALC and GPLC as a possible alternative to Pentox use, I will post when I know for sure it is assisting with Blood flow, it should do as Pentox is prescribed for claudication, ALC and GPLC should work as GPLC is shown to help also with claudication  :)
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Onemorestep

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Re: PENTOX - Side effects
« Reply #390 on: February 21, 2017, 02:07:33 AM »

Thank you all for the suggestions! Unfortunately I can't take acetyl l carnitine. For some reason it causes my muscles to seize up all along my spine and ribs and sometimes intestines. Along with that symptom I get rage, jealousy, anxiety, and a strange urge to drink alcohol or be sedated on other drugs. I only took it for a week before I had to stop because of those symptoms. 2g a day alcar. Kinda afraid to take any carnitine like drugs because of that. Alcar has some pretty intense effects on the brain. Just google "acetyl l carnitine and high affinity choline uptake" and some interesting articles come up like this one https://www.ncbi.nlm.nih.gov/m/pubmed/8095700/



Unfortunately these symptoms are starting to pop up on the Pentox. I imagine the gaba antagonism that goes along with Pentox in the PFC is having some kind of downstream effect on acetylcholine or there is an undiscovered mechanism of action. I have very bizarre brain chemistry. I've been diagnosed with fibro, chronic fatigue syndrome, and HPPD. These all make my responses to drugs bizarre or idiosyncratic. I hope to get off this last 400mg of Pentox soon because it is significantly affecting my sanity. So far I have seen no change downstairs coming off of it other than the tip feeling a bit colder.

As a word of warning, if you are a person who has a choline dominant brain with possible issues like low serotonin resulting from that watch out adding a drug like Pentox into the mix. High acetylcholine combined with low serotonin and high NE can cause a lot of nasty side effects. Even without the low serotonin high NE and acetylcholine will cause depression.

Perhaps I'll adjust to the one a day and be able to move up again. We shall see.

Once again thank you all for your words of wisdom and ideas!
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james1947

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Re: PENTOX - Side effects
« Reply #391 on: February 21, 2017, 03:49:53 AM »

Onemorestep

Again, I can just talk from my own experience.
I never used ALC because I was scarred by the possible side effects.
While on Pentox, I used also low dose Cialis and 100 mg coated aspirin (VED also but is not a medication)
I am a conservative man and don't want to take chances with what remain from my health.
I tried many supplements, medications and vitamins, but always just one at a time, I mean never more than one additional on the above treatment.
Bottom line, in my opinion maybe you should cut all and start to build your treatment from zero, except medications that are must for you according to your doctors. (in my case the 100 mg aspirin that I must take as blood thinner after a hearth attack 21 years ago)
But it is your health, and you should do what you think is best for you.
Good luck with the decisions :)

James
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Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe Erectile Dysfunction.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

Hrvat21

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Re: PENTOX - Side effects
« Reply #392 on: February 09, 2018, 05:06:46 AM »

I started taking pentox three  days ago, and now i find myself being constantly sleepy and, while at first i just felt warm, i became dizzy and feel very weakened and nervous and more sensitive to coldness. Will the side effects stop, and should i continue, ir it would be advisable to stop after this. Also, i get somewhat fuller flaccid, but my plaques are calcified allready, does it even make sense to use it? Does anyone know if using minidoxill (stuff for male pattern baldness) and pentox at the same time is inadvisable?
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Paolo

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Re: PENTOX - Side effects
« Reply #393 on: February 09, 2018, 05:45:39 AM »

Watch your blood pressure, dizzy is a red flag for it dropping too much!
Get a cheapish digital blood pressure monitor and start recording your BP regularly. I could be way off here but I thought Pentox was taken more for pain management, to date I haven't seen a member post it did anything to reduce a peyronie's curve?
Pentox I believe is for mainly treating PAD (peripheral Artery Disease). I believe it must be taken with food always.

If that's wrong then please post positives freely.
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pey ron

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Re: PENTOX - Side effects
« Reply #394 on: February 11, 2018, 11:43:07 AM »

As you know, I take insane amounts of pentox daily. I get dizziness and blurred vision whenever I go for a brisk walk that involves steep hills to climb. Unfortunately the BP arm cuff is a bit too big to carry around at all times, but I should definitely have it in a backpack next time I go. My BP has always been 120 over 90 or 120 over 80. Under my current regimen, I've been getting readings of 90 over 60 when at home and resting, which are still not an issue, but lower than that it can get really dangerous, to the point of brain damage I believe.
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TonySa

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Re: PENTOX - Side effects
« Reply #395 on: February 11, 2018, 11:55:00 AM »

Peyton, why not cut back on the dose if bp is so low?  With meds there‚Äôs often a therapeutic range where going over gas no added therapeutic benefit-just more risks.
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pey ron

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Re: PENTOX - Side effects
« Reply #396 on: February 11, 2018, 04:00:26 PM »

I can't find it anymore but a long time ago I had found some paper that said that the dosage at which pentox is prescribed to humans is several times below what would be needed for an effective antifibrotic effect. That's probably why it only works and fully dissolves all scarring if and only if started soon after the injury, like in the first 2-3 months.
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Hrvat21

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Re: PENTOX - Side effects
« Reply #397 on: February 11, 2018, 04:30:24 PM »

Does it make any sense to take it after 6 years
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TonySa

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Re: PENTOX - Side effects
« Reply #398 on: February 11, 2018, 05:34:29 PM »

And where did you find it is only effective very early on?
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Hrvat21

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Re: PENTOX - Side effects
« Reply #399 on: February 11, 2018, 05:47:31 PM »

One more thing, do you guys think i can take minoxidil with pentox?
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