PENTOX - Side effects

[james1947]

John

Start taking one 400mg ER Pentox a day in the morning for one or two weeks.
I think you will not have anxiety if you will start in this way.
Good luck

James

[Blacksammi]

According to my Doc there is no problem stopping Pentox in any dosage immediately if required, or starting again on higher dosages immediately either.  As a test for headaches as a side effect recently I stopped 4x400/day for four days with no problems (and with no reductions in headaches either) so recommenced on full rate again immediately with no problems. Having ct scan next week to investigate headaches further. I know there are many other drugs that require gradual increase/decrease regime.My
My bend is continuing to improve- almost worth the headaches!

Blacksammi

[John B]

I've been wanting to start this Pentox badly, but I stopped taking a beta-blocker (atenolol) exactly 2 weeks ago, and my heart rate is still high. It averages 105 beats a minute a lot of the day, when sitting.

Do you think it would be safe to take a single 400mg Pentox with the heart rate at around 100 beats a minute, and has anyone experienced rapid heart rate from Pentox?

I really want to start taking this stuff...

[MattFoley]

I didn't experience fast heartbeat but I did and still on occasion experience some anxiety. Not bad enough to get me to stop.

I highly recommend that you discuss the heart rate issue with your doctor.

[swolf]

Can you tell me how much Stabillium you are taking ?  I take it as directed on the package, but do not notice much if any effect.  thanks

I now take one capsule of Stabilium a day and that seems to be enough. That's one box a month, so around $13 a month. I should probably stop use for a few days to see what the effect is - maybe I could get by with less? I notice a definite benefit so will continue to take it. It has helped immeasurably.  

[KAC]

A question about pentox:  I've been on it daily for about a year and a half now.  I don't seem to have side effects, though I wonder if it gives me anxiety.  Peyronie's has been stable for about a year as well--no new inflammation, no growth in plaques.  My uro seemed to think there is little chance of recurrence.  So now I'm wondering about ending the pentox and VED.  Any thoughts?  I don't really want to be on a drug for life, but I don't know when to stop it.  And since I asked my uro for it, he assumes I'll figure it out.  I'd love any guidance from people who have been on it for a couple years.

[egghead]

Is your plaque reduced/gone? Curvature degree? What else are you doing for treatment/diet/workout?  

[KAC]

No, plaques are not gone.  Do anybody's plaques disappear after a 18 months of inflammation?  I kind of doubt it.  I've continued to take pentox in hopes that it will keep the plaques pliable for a long time and prevent calcification.  If Xiaflex becomes a realistic  solution, I'm interested.  But I'm interested in opinions about the benefits of long term use.  How many years are others of you staying on Pentox.  Are you just planning to stay on it for life?  or in case some other solution becomes practical.

[Hawk]

Egghead,

Don't click on Quote when you reply.  Click on reply button at the top of the topic.  Forum rules restrict quoting entire posts especially when there is only one post before your post.  Makes no sense to  quote a whole post we just read moments before.

[egghead]

KAC; I plan on taking it for for life if I have to. But I'm hoping that once I fix my low T and get these plaques beat, I won't have to.

I've upped my dose to 4x400mg per day. Side effects include bouts of insomnia and anxiety for me. Benifits are painless sex and perceived reduction in curvature and thus, happiness..

[funnyfarm]

I have discovered that taking pentox with a teaspoon of coconut oil prevents any stomach upset in my case.   I did not have bad stomach issues but would often take the first one or two on any empty stomach (I often skip breakfast in lieu of gym/yoga) which would cause moderate distress sometimes.   This approach prevents any issues and also unrefined virgin coconut oil is a very healthy fat.  

Just a possible tip for anyone having difficulty.

[Noway]

I found taking one pill of pentox instead of three does just as a good job. If your having really bad side effects just take one instead of three. Pentox and Cialis in combination work really good. Pentox makes your penis look more fuller expecially in the flaccid state.

[muffslayer]

Hey guys, I'm wondering if any of you guys taking pentox are getting this side effect.

It's like I do something, I'm not all there, and literally forget about a few minutes later.

For example I took some fish oil, then a few minutes later surfed the web, then was going to put in my excel spreadsheet that I had taken some fish oil, but couldn't remember if I actually had taken any.

My focus and short term memory has gotten bad.

Or I go into another room to do something, but I do something else I notice I need to do, then leave the room, and 10 minutes later I remember I didn't do the initial thing.

Another recent tangible example is this. I took a pot out of the oven with oven gloves, it had been in there for 2 hours, then I take one oven glove to lift the pot lid off and burn myself, it was so stupid I did that. The only reason I could think of is that pot doesn't usually go in the oven to cook stuff, but rather on an electric hob, and I often lift the lid off with my bare hands to check on what evers cooking (soup for example).

But it feels as if my focus/short term memory is being effected, and I'm not sure if this is the pentox or not, so I want other people's opinions. I recently increased my dosage btw to 1 in the morning, and 1 before bed, while before it was 1 before bed. But I not sure when this effect started since it's been a gradual thing, so it could have been happening on the lower dose.  

[muffslayer]

By the way I'm 25. This is an example of the memory loss/focus thing. I was meant to write this in the original post and was thinking about it while typing my original post, but only now just remembered to add it after I had finished replying to a different thread.

Also another thought came into my head, could it be gotu kola causing this side effect?

[funnyfarm]

Are you sleeping okay ? Pentox is noturious for reducing restorative sleep which could impair memory,  especially if you build up a sleep deficit.  Having said that, I had several side effects from pentox, but memory loss was not one of them.  

[RoyHobbs]

I experience the "where did I put my keys two seconds ago" syndrome, but I feel like it occurred before Pentox. And it hasn't gotten worse and I take 6 pills a day. But it seems to affect everyone differently. I started experiencing possible heart arrhythmia at about 4.5 months in and am currently getting checked out. But if it's not life threatening I'm sticking with it. Because after 5 months, my girth has increased.

[james1947]

Muffslayer

How long time you are taking Pentox?
How long time you have this side effect of short term memory/focus loss?
If they come together, you may stop for a while and see what happening.

James

[DO]

 Did you know sleep disorder breathing can cause memory loss or memory fatigue! If Pentox is keeping you awake, there can be a problem.
I take two 400mg in the AM and my 3rd in the afternoon before 5.... so I can sleep!
Oh yea sleep apnea can cause erectile dysfunction too! When we get into rem sleep, men can have 3-5 spontaneous erections. But if apnea is preventing you from getting into rem...then when you want it to work it will not!

[MattFoley]

Guys, does anyone have any info on Pentox interfering with healing from a viral infection?

I can't seem to make the infection go away and I'm wondering if Pentox may be causing me not to get over it.

Thoughts?

[IhatePD]

Matt,

I told my GP that I was taking Pentox and he told me that he knows a lot about it since before becoming a MD he was in medical research and had a grant to study Pentox. He told me that if I got an infection while on Pentox to come back and see him ASAP. He said that Pentox can interfere with the body's ability to fight infection.

[james1947]

Matt

From my experience, if I have flue and don't stop Pentox, the flue don't go away.
3 times already.

James

[MattFoley]

Damn!! Thanks guys. I have this infection and it won't stop so following your advice, I'm gonna stop taking the Pentox effective immediately until the infection is gone.

I appreciate the feedback.

[funnyfarm]

You need to have your WBC count tested.  Mine dropped while on pentox, and I did have one bad case of the flu which I normally never get.

[Norm]

I find this very eye opening. I have been fighting a persistent gum infection that just won't quit. My dentist is at his wits end on it and is sending me for a biopsy because he cant get it to go away. Perhaps the Pentox is not helping me?

[james1947]

Norm

Try stopping Pentox for a few days, a week. It helps me, maybe will help you also.

James

[MattFoley]

I've never had any kind of infection like this.

It's been going on for over a week. I started getting chills and in minutes, I go into convulsions and can't keep my body still. Then, after 15-20 minutes of that, my body temp. starts rising along with the worst body aches I've ever had. It's an unholy nightmare.

I found this:

http://www.ehealthme.com/ds/trental/viral+infection

So, as much as I hate not taking the Pentox, I'll hold off until this infection is over.

[Craig]

This is interesting. Now looking back, I got sick for a week or two right after starting Pentox I think. I can't remember if I modified my Pentox intake while I was sick (I don't remember if I suspected a connection). One way Pentox may lower your immune system is the interference it causes with sleep. If I don't get sleep, my immune system goes way down.

And Matt, aren't you on a lot of testosterone boosting supplements that quadrupled your testosterone levels? Testosterone also inhibits your immune system, so it could be that.

[funnyfarm]

Matt, I would error on the safe side.  When I stopped for 2 weeks there was no hardening of the scar or any issues like that.  I think the improvement is cumulative, and if nothing else it will give your body a little less stress for a few weeks.  

[MattFoley]

I agree, guys. I'm gonna hold back on Pentox until this infection is done.

And yeah, I'm on testosterone but there's no way I'm cutting back on that. Hopefully it'll be over soon.

Thanks again.

[Craig]

I'd temporarily increase your intake of Vitamins C & D, zinc, and magnesium to boost your immune system. I noticed I get sick a lot less ever since I got Peyronies and started taking a bunch of vitamins and supplements.  

[funnyfarm]

Matt, doing any better buddy, you did not sound too great last week ?

[MattFoley]

Thanks guys, I appreciate your thoughts and advice.

I was definitely in a bad place last week. Aside from the fevers, convulsions, and body pain, my liver and kidneys started to fail. My legs and lower abdomen started filling up with water. It looked like I was pregnant!! Scared the hell out of me. The doctor told me I was leaking protein and there was blood in my urine. They had no idea what I had and why it was happening.

After I got out of the emergency room, I went down to the vitamin store and bought a liver detox product and a kidney detox product. The next day, my legs and lower abdomen completely drained and went back to normal. The fever, chills, and body aches have stopped.

Now, I'm not gonna attribute the fevers and chills stopping to the detox products but the draining from my legs and abdomen was certainly due to the detox supplements.

So I've started taking the Pentox again.

Thank God this is over because it was some of the most horrific pain I've ever felt.

Again, I appreciate your thoughts, guys. God bless.

[funnyfarm]

Glad to hear you are doing better and back on the "vitamin P"

[Craig]

Glad to hear you're doing better. What do you think caused the liver and kidney issues? You think it was something you were taking?

[MattFoley]

The liver and kidney issues were related to the viral infection. Plus, I wouldn't let my body rest by going to the gym and doing some grueling manual labor as well.

This morning I got a call from the doctor telling me that they overlooked a small detail: I have a urinary tract infection!! They checked my urine 2 weeks ago and now they tell me!! So the doctor prescribed Cipro, which you guys probably know is a strong antibiotic so the final remnants of this situation are getting handled as of today.

The interesting thing is that I'm not feeling anything from the UTI. No fever, no chills, no kidney or liver issues...nothing. So I'm guessing it's a low-grade infection.

[james1947]

Matt

Sometimes you can't feel an urinary track infection even is a high grade.
Don't assume:

So I'm guessing it's a low-grade infection.

If it was, they was treating you with a less strong anti biotic.

James

[MattFoley]

Thanks James.

To add to my symptoms, 3 days ago I added restless leg syndrome to the growing list of symptoms. This is associated with a suffering kidney situation.

[Litani]

I have been taking Pentox for 15 days without side effects.  Today I saw few hives on my body that itch.  They are scattered (total of 5 locations) and nothing drastic.  Can this be a side effect?  Allergic Reaction? Should I be concerned?  Has anyone had this kind of reaction to Pentox?

[james1947]

Litani

I didn't had this side effect and didn't read about other that had but I am proposing you to stop taking Pentox for few days and see what happening.

James

[Litani]

Thanks James for the advice.  I stopped pentox for 4 days and the hives were gone. I restarted  it. It has been almost two weeks and no reaction. It must have been something unrelated.

[Litani]

Two weeks ago I had a doctors appointment. He increased pentox from 2 a day to 3. At the same time I switched CQ10 with ubiquinol.  I have been experiencing constipation for a week and a half. It is more like hard stool. Has anyone had the same issue with either product?

[MattFoley]

Yes, Pentox started constipating me when I went over 4 or 5 times a day. Take Metamucil. It will help.

[dplookin]

When you take a Pentox with a meal, make sure you drink at least 12 ounces of water at the same time.  This may help solve your problem.  

dplookin

[MtnSurf]

Yeah I'd drink lots of water. Your body should adjust to it in a week or so. I'm pretty sensitive to prescription drugs and I had no major issues with pentox.  

[dioporcolorisolvo]

I've a deep doubt.
Has anyone had problems of tendonitis after beginning of pentox's treatment?

Thanks very much.

[MattFoley]

dioporcolorisolvo, yeah, I do. Both elbows are tender and have not healed. Whether this is due solely to Pentox or a combination of factors, I don't know.

[powderpowder]

Anybody get headaches in the beginning of taking pentox
im taking 800 mg per day, spacing out each dose by 4-7 hours.
Taking it right in the middle of my meal with CoQ10 and Vit E.

I talked to the pharmacist and they said keep taking it for a couple more days and your body may get used to it and the headaches will go away.
Really hope this is true and this happens. I need Pentox to combat this disease (5 months in since my injury and have one tiny plaque)

[ComeBacKid]

Dry mouth, upset stomach if taken without food, and constipation all side effects of pentox, and oh yeah on the higher doses, I had a light headache all the time.  Now the good news, this stuff really does work especially at the higher doses of two and three pills per day, but once your done with it you'll want to take a  good probiotic.

[james1947]

ComeBacKid

What you mean by:

you'll want to take a  good probiotic

Can give an example?

James

[dplookin]

ComeBackKid.............Constipation is a side effect of Pentox for a lot of people.  If you are in your 30's, you have a 50% chance of becoming constipated.  If your in your 60's, you have a 72% chance of becoming constipated.  That's why I quit using it.  I found these statistics somewhere on the Internet.  Don't remember where.  The older you get, the better chances of this side effect.  I found that Nothing would eliminate this side effect.

Just FYI