PENTOX - periodical updates and observations

[Noway]

Skjaldborg

Im seeing a peyronies disease specialist right now... and he said that injections wont cause scarring to a flaccid penis. Theres two of them actually one is I guess his assistant. He explained where they put the needle and how he does it. He also told me that the scar tissue forms when the penis is erect. Im pretty sure he cant do much worst then the first women urologist that I seen all she did was grab my balls really hard where I yelled then im like what are you doing? shes like I got to check then im like its my penis thats the problem.. then she said its all in my head and that someone at 21 years old cant possibly have anything wrong with his penis and left it at that. I actually still get pain every so often from that too in my nuts like someone sacked me down there and it feels unconfortable.

[ComeBacKid]

I noticed some of you are talking about pentox, and some have PMed me about the drug.  I am getting ready to start it again in the next month, when I was on it before with just pentox it helped me drastically and improved my penis.  I did experience some side effects:

1.  Dry Mouth
2.  Increased Sweating
3. Irritation/Agitation/Quick to get angry
4. Sick stomach if not taken with pill
5. Shortness of Breathe

None of these were strong enough however to cause me to quit taking it, I finished my course.  This drug is the best thing I've taken so far.  The only thing that concerns me is why does it make you sweat more, and make it harder to breathe?

Comebackid

[charlie44]

Have had Peyronies since late April, new doctor put me on Pentox 2 weeks ago. 400mg 3 times a day. I have a mild case (at this point) with an indentation on the left side halfway up.

What should I expect from Pentox and how soon would I most likely see any benefits? I know these are hypotheticals and everyone differs, but appreciate anyone's experience and knowledge in response.

Thanks!

[Worried Guy]

I have to be honest with you as I don't want you to be disappointed. Don't expect much and not for about 4-6 months if anything.  Very slight changes which could just be your body healing anyway.  This is not a cure. I got my hopes up only to be frustrated.

[charlie44]

Yeah....I know....it might not do anything and if it does, could be a while....then as you mention, is that just your body healing or is it the medicine? But I did want to be on it as it possibly could do some good. You know how it is with this disease....if there is something that "might" help....you take it.

[Worried Guy]

Exactly how I feel chap. I'm still taking it at the moment and will just in case it does help.

[ComeBacKid]

It worked for me, right away I noticed my penis hung bigger and got more full during erections, it also took away most of my ED problems.  Slowly over time my penis got more flexible since it was hardened all over from the plaque.  Then after 7-8 months of being on pentox I stopped it and it just stayed soft and healed for awhile, then slowly over time after not being on pentox it began to harden again and the peyronies came back.  It's definitely not a cure, but I saw significant improvement!

Comebackid

[fubar]

That's the answer I was looking for.I have noticed the same effect.Maybe it keeps the plaque from calcifying?That would make a better situation for future remedy if our dicks do not turn into fossils.

Fubar

[crashbandit]

That's the answer I was looking for.I have noticed the same effect.Maybe it keeps the plaque from calcifying?That would make a better situation for future remedy if our dicks do not turn into fossils.

Fubar

LOL, imagine fubar's fossilized penis in an archaeology dig on the discovery channel  

[newguy]

It's easy to see improvement in terms of improving your current state. However, as you are new to peyronie's and your condition is mild at present, a big help from pentox may well be reducing ongoing and future damage caused by your condition. You should stay on it for 6 months at a minimum and evaluate your condition at that time. Ideally I'd say that a year + would be a better timeframe. It's generally well tolerated so has a bigger upside than downside.

[charlie44]

Agree....I plan to stay on it at least a year. My doctor asked to see me again in 3 months, so he is (and I) are monitoring the disease and any progression (or lack thereof) closely.

[ComeBacKid]

Crash,

I wouldn't want to be on that dig  

[fubar]

Combackid and crash

What if the fossilized revieled the cure? Naa I would not want to find the nasty frozen soldier either.

Fubar

[jamesmetairie]

I got the doppler at Tulane in New Orleans almost a year ago. Tulane prescribed traction. I didn,t do it. Since then been seeing a doctor at Oschner Hospital in the New Orleans area (jefferson). He prescribed pentox 3 times daily. My stomach didn,t agree,but I took 2 daily. He recommended vacuum therapy. I didn,t do it yet. He gave me a scrip for the generic form of  viagra. It made my head feel like it would explode with  sinuses locked up,etc. He took me off of pentox a few days ago and said it was at the point where pentox would do no more good . He said he didn,t want to cut on me at this time. I agreed 100% with that idea.
No pain observed from the get go. Did have slight tingling occasionally many months ago.
No worsening of the curvature observed.
Still having the blood flow problem when trying to keep an erection. It is possible, but it ain,t easy.

no excuse why i didn,t start vacuum yet.
i still take blood pressure medicine(lisinipril) daily.
still drink several beers daily.
still work rotating shifts weekly and it,s still ain,t easy.

[fubar]

James

I understand rotating shifts and having to find time for therapy.But what are you waiting for? Miracle maybe?.I would definately choose a device and find time for it.Im not always on top of my game and have been struggling lately.Then again i find time for some kind of stretching.

Not having great erections try low does cialis.I would consider staying on pentox.Relief seems to be a combinations of things for me atleast i have to have pentox,  cialis ,ubiquinol and a mechanical device to maintain any kind of penis health.Sad but true  better off with than without.

Fubar

[qweeny]

Hi, Pentox definitely seems to be having a good affect on my partner, he also feels a bit sick if he doesn't eat first- otherwise no problems

[crashbandit]

Thats great Qweeny, may I ask what good effects you guys have noticed since the start of pentox?

Thanks

[qweeny]

Crashbandit- Sure  . Well, my guy is also taking CQ10, Acetyl-L-Carnitine and L-arginine as well as Pentox, so we are not sure what is working most, but I'm assuming Pentox because of all the good experiences of others too taking it. Anyway, he has been taking Pentox for about 2 months, the supplements for about 3. He says he has noticed a the 'lump' getting smaller, a reduction in the curve and he has really hard erections  . It hasn't helped with pain so far (during erections), in fact we think that all the extra blood flow is causing it to hurt more, but with all the other positive effects, we are hoping the pain issue will resolve soon too.

Are you taking Pentox?

[crashbandit]

Yep, I'm taking pentox for the past 10 months with a couple interuptions of a few weeks. I'm just taking the 2x daily doses and I feel it does help alittle bit with keeping good blood flow. I've been on and off many other treatments, which isnt good because i get discouraged easily when it dosent seem to be helping and dump it. So that's really good you guys have been consist for at least a couple months because it does take along time to work sometimes for many different reasons. Just stick with those things you got going as they are the best for oral treatments, expecially since it seems to be helping.

The pain is never a good thing but to see changes in curves definitely out weighs the pain, who knows maybe the pain in this case is a good thing. I'm sure he knows the difference between a good pain and a bad pain and also different pains, which should always be monitors closely. You sound like a great girlfriend and he is very lucky to have you as Peyronies Disease can be very difficult for a guy to go through and of course you too:)

[qweeny]

Crashbandit- my guy is on Pentox 3x per day, I thought that was the recommended dose? I know we are newer to this than you, but I think to see improvements you need to stick at whatever you are taking for at least 6 months. Some supplements take a while to build up in the body and if you change and swap, that could just be confusing your body. Having said that, I understand the frustration and discouragement when you feel something is not working, we were hoping the pain may have resolved at least a bit, but it has not yet. However, any improvement is a good think so we will stick with it.

I'm not sure about the pain thing, all I know is that over the last 2 weeks or so there has been no change in how much it hurts and it has hurt more in the recent two months. Good pain? Not sure what that would be, but I'm not a boy so it's hard to imagine. In the acute stage I thought the pain levels could get worse before they got better?

Thanks, Peyronies is difficult to go through for us both, but we are positive and try to look forward as much as possible. At first it was scary, but now we have accepted the challenge! What keeps us positive is the progress so far, the knowledge that this can make us stronger as a couple and the realization that we are strong enough to deal with it. We are limiting sex to 3 times per month, but have made a pact that when he gets better we will catch up for lost time  

[kmdguy]

Hi there,

I posted an introduction about a month ago just before my doctor prescribed me Pentox. I said I would try to keep an update as to any possible progress.

It's been almost 30 days on Pentox. My doctor prescribed 2x400/day. I have no ill side effects at all and physically feel fine.
My first observation which I thought was curious that doesn't have to do with Peyronies: close to 10 or 12 years ago, I developed an almond shaped soft bump on my forehead and simultaneously a soft lump under the surface of my skin on my lower right thoracic region, residing on my last rib lined up mid clavicular (I'm a nursing student so pardon the geek speek)... a small ping pong ball sized lump under the skin. I went to the doctor way back and he determined that it was just a harmless lipoma. It could be taken out if I wanted go undergo surgery for it, but it really isn't any cause for concern. It was just a small benign fat tumor. No big deal so I've just left them as they weren't that big of an aesthetic problem for me to warrant specific surgery.

OK, fast forward to Pentox. The first thing I observed after starting it, within 3 weeks the lump on my forehead is virtually gone. This has been stable for over 10 years and it must be from the Pentox unless a remarkable coincidence has occurred. The larger lump on my rib is measurably smaller, for realz, about 50% or more in reduction. There is no questioning this decrease in size, my wife even commented that my forehead lump is not even detectable when before it was ALWAYS visible for years. Not that this was a big issue for me, but it is interesting to note.

My second observation: For years I have had tiny blue spider veins just behind my medial malleolus (ankles) on both feet. Again, not a big deal, but they were there. Again, after 3 weeks of Pentox, the veins on my right foot are barely visible, probably 90-95% obscured. The ones on my left foot are at least 50% less visible. Again, these were things that were stable for years and that I was familiar with their regular appearance. 3-4 weeks on Pentox and this is the result. Again, not penile observation but interesting to note nonetheless.

Third observation, prior to Pentox, I had a very pronounced dent on the right side of the penis (which originally appeared almost 1 year ago). The dent had a relatively deep trough (you can see an illustration of it if you refer to my Introductory post). Four weeks of Pentox and that trough is now beginning to shallow up. The depth IS slightly less and I can absolutely compare the before and after shape and see that is the case, and the shape is different. Now, is this due to normal shape shifting of the disease itself, or a direct result of the Pentox, who can quantify that for sure, however, it is an observation that I can make as a difference since starting Pentox. Certainly the dent is still there but it is definitely trying to become more shallow. I can understand that these things take a long time, and this is just one small step, but it at least gives me some encouragement that something may be happening as a result of the medication when I factor in the other observations I can make.

I'll report back again in another month with any noteworthy updates.

Cheers,
Dan

[james1947]

Hi Dan

Thank's for the input. Very encouraging that pentox worked for you so fast.
I will see my uro next week and ask him prescription. Hope it will work for me also!

James

[RichRN]

I discovered a pea sized nodule 11 months ago. I started a regimine of Pentox, Vit E, Vit C, SOD, and a long list of others. I did not do the cialis due to cost. No insurance. I even got the VED set up. After a large amount of money spent, that pea sized nodule is now extends about 2 inches with a large marble sized nodule towards the base of penis. I can feel plaque almost entire length of flacid penis. On the good side, pain has improved. The upward curvature is well appreciated by my girlfriend. But plaque appears to be still growing at a slow rate. Without vitamins, symptoms may be worse, who knows?

[james1947]

The fact that the plaque growing at a slow rate and pain improvement shows (in my private opinion) that the treatment you are doing is helping.
You are not yet in the stable stage so you must continue the treatment to reduce the damage. You may change some intakes from your list.
Read on the forum how and if some of the vitamins and supplements has helped others.
How many Pentox you are taking daily? How are your erections? Did your lost length or girth of your penis?
James

[james1947]

qweeny

You have written regarding improvements of your partner from taking Pentox at November 18, 2011.
Four months had passed, can you give us an update regarding the situation?
I am taking also Pentox for three months now (2*400mg/day), I will be happy to hear any newses from people that are taking it for longer time.

James

[james1947]

Hi Dan
kmdguy

You have started this very positive topic regarding Pentox on January 6, 2012.
Do you have some improvements or regression since that time?
It will be interesting and usefull for the forum to have your update.

James

[goodluck]

Your improvements with Pentox are excellent and encouraging.  Your comment about the spider viens fading got me thinking about an over the counter product made by Life Extension that contains Diosmin 95.  It is used to reduce and/or eliminate spider veins.
Read about it in more detail here.
http://www.lef.org/Vitamins-Supplements/Item01042/European-Leg-Solution-featuring-Certified-Diosmin-95.html?sourcecode=SNC206E

I just wonder if it could help with Peyronies?

[james1947]

I don't know if the

over the counter product made by Life Extension that contains Diosmin 95.  It is used to reduce and/or eliminate spider veins.

But Pentox, as I have posted in the topic "Pentox? In my case has worsened situation" (under "Oral Treatments for Peyronie's Disease") had same effect on me after one month already eliminating almost all the small blue veins from my face and feet. It seems the red blood cells can move much better in the thin veins.
James

[goodluck]

From what I can find on Diosomin 95 it dilates and strengthens  blood vessules. It also makes them more elastic.  As a result you get less inflamation and better blood flow.
It is a flavinoid and made from fruit.  Often oranges.
It has been used in Europe for years on vericose veins and hemmeroids.

Can't find much more than that and can't tell if anyone with pyronies has ever used it.

[cowboyfood]

In some of my recent posts, I stated I had a dent which seemed to manifest on the left side over a year and a half ago.   After a year since its manifestation, it had progressed to looking like one of the dents in kmdguy's illustration (see his first post).  

Since that time, it "resloved" or "improved" by about 80%, and is not that noticeable, it's very smooth and not deep at all, looks somewhat normal.

I was on Pentox for about a year before it manifested (meaning it was visually noticeable, I could "feel" a dent for some time before it visually manifested itself), and stayed on Pentox until about last October.  I continued using the VED the entire time (basically for the last three years).

From about late September until the present, the dent improved dramatically.  I'd say it really ramped up its improvement in November of last year according to my photos.

I'm thinking that the Peyronies Disease did its thing, but was mitigated during the acute stage by Pentox/VED, and after the acute stage the Pentox/VED usage really allowed for some improvement.

-CF

[james1947]

cowboyfood

I am happy for you that your treatment worked so good.
Your post is also very encouraging and it shows that even is not a silver bullet, the combination of Pentox and VED it make things close to miracles, especially for people that begin the treatment in the early stages of Peyronie's.
And the key is consistency!!!
I would like that all the new members will read your post and not to wait to see what will be as many of the uro's are advising.

James

[james1947]

I don't want to open a new topic so I will make a Pentox update here.

I am two months on 2*400mg daily Pentox, 4 months ~17mg Viagra and 6 months on VED. Have light flue like symptoms and cough.
Regarding Peyronie's:
I have nice night erections even with all the deformities.
Flacid state more full and not contracting anymore inside my body.
Still sometime rigid flaccid state.
No change in the plaques, I am not expecting before six months on.
Not Peyronie's related:
My platelets bellow 840,000 for the second month (more than one year was above 1,100,000) - Can be Pentox related?
My leukocyte is 26,700 stable - Can be Pentox related? It was going up all the time.

My problem is with the Hemoglobin that is very low at 10.2. Have somebody any idea how to move it up? Is down because many phlebotomy's that I had made in the last few years because of sticky blood.
My sugar today (not fasting) 103. Not really under diet, just keeping out of sugar best as I can.
My cholesterol on 189. I have exaggerated in the last month with fat cheeses and butter.

I will be happy to hear some opinions.

James

[ThisWontWork]

Today I started my pentox(trental) - cure, 3x400mg and 2x1000mg L-arginine. I will report back later.

[Noway]

james1947 go on cialis once a day and ditch the ved

[james1947]

Noway

Thanks for the advice.
I changed the Viagra and taking Cialis 4mg (approximately, more easy to cut the 20mg to 5 pcs than 4).
I am doing VED also more than 6 months and will add this week (hope the shipment arrive to me this week) of 1000mg L-Arginine and 2*100mg Ubiquinol.

James

[Old Man]

Noway:

Please advise why you say "ditch the VED"! I need you to explain to me and many others the reasons you can make such a statement when it has helped so many. It is a known fact that it does not work for everybody, but has been shown to help a greater of percentage than not helped.

In fact, many of the known Peyronies Disease specialist urologists are now including it in their regimen of treatment. Waiting for your explanation.

Old Man

[warming]

hi there.
I'm 36, and I live in Denmark. I was diagnosed about 1 year ago, and now have an upwards curvature of about 35-40 degrees right below the head, and a slight indentation on the right side.
Seems pentox is what most of you are recommending, problem is, I have not been successful in finding a urologist here that will prescribe it.
In fact, last one I went to wrote off Dr.Lue's work entirely, calling him a 'quack'. Told me Nebitt procedure was only thing that works.
I believe the truth can be found in the experiences of the people suffering from the problem, rather than from conservative doctors who don't follow the research being done.
So, my question is: Can any of you recommend a specialist I should go see, in another country? Preferably somewhere in Europe.
Really want to get on Pentox asap.
Been on neprinol, PABA, L-Cartinine, Omega-3, Vitamins.
Been using traction and heat therapy (electrical blanket). No lasting effect yet.
I do notice though, that each time I've had the blanket wrapped around my penis for an hour or so, the curvature in my erection is slightly better (maybe 5-8 degrees less), and the tissue feels more elastic. That only lasts for about an hour though, then it goes back to "normal".
Really appreciate this forum!
thanks

Dean

[Luciano]

Well here in austria I would rather go to a general practician that to an urologist to obtain pentox.
They all know pentox for other indications and know the side effects.
If you go and see a general doctor, and tell him you want to take pentox, (say you only want to take 2. With 3 per day all seem to have problems, they seem to think though that 2 a day will do no harm) and ask him if he will prescribe it to you. Tell him the truth. That doctors in the US prescribe it and you can add that you are stumbling into depression because you have not met an urologist in your country that knows what to do with your Peyronies Disease. (even general doctors know that there is no miracle cure for peyronies).

If he thinks it will do you no real harm, he will also think its better to prescribe it to you than have you order it without prescription in the internet. Ask him if there is a physical reason not to prescribe it.

I got my first dose of pentox like that, from a general practitian. I went to see him as private patient. and asked him to look at me if it was ok for me to take pentox. He said he didnt think there would be a problem with me taking it. So I asked for the prescription. and he gave it to me. (now i get it from a pharmacist without.)

That is my advice. Urologist never like being told what to do. a general practitian though, if you tell him you trust him and not the urologist will feel good. ok, it cost me 50 euros to go and see him as a private patient, but it was worth it.
those are my suggestions.
Luc

[YoungOne]

Has anyone tried this: taking pentox 2x daily Sunday-Wednesday and 1x daily Thursday morning. Meanwhile, cialis 1X daily all week. This being if you expect to have sex on Friday....and on Friday taking both pentox and cialis an hour b4 sex?

Just curious. I guess to sum up my question....a gone take pentox and cialis before sex after letting their system somewhat reset from the week's intake of pentox..

[james1947]

YoungOne

Pentox is not an ED drug. Pentox is making the red blood cells more flexible so they can flow also in very thin blood vessels and supplying oxygen to the organs.
It should be taken daily for long time to have effect, minimum 2 per day as I learned on the forum.

James

[YoungOne]

James, I know. However, I'm 26 in great physical condition and I only weigh 180. I run and workout daily. I experience a noticeable difference in flaccid and erect state when I take just one pill. This week I combined cialis and pentox for the first time and was getting erections while sitting in my desk at work. A big difference for me. I'm having sex tonight with a girl that last time I had some difficulties. I was just wondering if it was ok to take pentox and cialis together before. I typically take them on a daily basis but I haven't taken today yet.

[james1947]

YoungOne

Hope my answer reaching you in time, I went to sleep yesterday night after my post. We are 12 hour difference in time.
I am happy for you that it works this way.
I will try also the effect, who knows? It may help, but with Viagra as Cialis not helping me.

WISH YOU GOOD PERFORMANCESS TONIGHT

James

[steamer]

i've been taking pentox for a few weeks now and the pain i was experiencing has greatly diminished. not totally gone but less. i also started ubiquinol around the same time. most of what i have is twinges in a flaccid state, sometimes enough to stop me in my tracks. i've also found loose pants and going "commando" helps keep the binding effect down. hanging loose i guess you could say.
i really think the pentox is starting to work for me. i take a number of other supplements also.

steamer

[james1947]

steamer

Glad to read you post regarding the improvement with the pain.
Pentox is indeed the first line medication for this disease an hope things will improve more.
The combination with Ubiquinol and other supplements are giving good results.

James

[steamer]

here's my entire daily supplement and drug intake.......
pentox, 400 mg x2
l-arginine, 1000 mg
ubiquinol, 100 mg x2
mixed vitamin E, 400 iu
vitamin D3, 1000 iu

[steamer]

add the following to the previous post. somehow i screwed up and sent before i was done...

vitamin C, 1000 mg
wild alaskan salmon oil, 1000 mg
alpha lipoic acid, 100 mg
hawthorn berry, 1530 mg

the last blood work i had done came back very good, which is a good thing because had they not and the liver readings weren't right my uro would not have prescribed the pentox.

steamer

[finarod]

here's my entire daily supplement and drug intake.......
pentox, 400 mg x2
l-arginine, 1000 mg
ubiquinol, 100 mg x2
mixed vitamin E, 400 iu
vitamin D3, 1000 iu

i'll share a remark on a detail that i find important...

wouldn't it be wiser to take 200iu*2 vit E, instead of just one 400iu, considering that ubiquinol, that you take two times in a day, enhances vit E's efficacity, add to that its combined effect with pentox against fibrosis?

I intend to begin taking coq10, and i'll be doing that. i don't think that a 400 iu vit E capsul taken in the morning would get into combination with ubiquinol and pentox that you take in the evening... am I wrong?

[steamer]

hadn't thought about that so i'll see what i can find on it. thanks for the opinion.
i forgot to mention the daily 5 mg cialis.
some of the supplements i've been taking for years for various reasons, heart, sugar, circulation, etc.



steamer

[james1947]

steamer

Just one remark regarding vitamin C.
I have read somewhere on our forum (don't remember the topic location) that our body is not able to process more than 500mg vitamin C per day. The other 500mg (from the 1000) will just go out with the urine, in some cases will make more damage than help.

James

[steamer]

i haven't read that but it's worth looking into. thanks for the heads up.

steamer