Stem Cells & Adult stem cell injections for Peyronie's

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james1947

Interesting article regarding stem cells, pros and cons regarding using them. Someone get Nobel Prize on his research on the subject.
Analysis: Reprogrammed cells open new medical window - Yahoo! News

James
Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe ED.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

yyy

5th of November is my day. Im scared but also look forward to doing it. It could really change my life. I'll keep you all updated

Sargonnas

Quote from: yyy on October 08, 2012, 07:17:46 PM
5th of November is my day. Im scared but also look forward to doing it. It could really change my life. I'll keep you all updated

:D Awesome! For sure its gonna benefit you. Are we living the future maybe?? Could a damaged penis be healed by healthy cells injected to it? And more importantly would this treatment somehow reset the inflammatory and possibly autoimmune loop in our penises? I just would like the world situation wasnt the current one. Not good for this kind of research. 2012 UFO´s, please dont change human penis researchs! If something, share your knowledge in repairing sexual organs! lol

james1947

yyy

Good luck, I will pray for you. Wish you November 5 will be a new beginning :)

James
Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe ED.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

rd

Just another update, all the original lumps treated are gone plus the one on th left side which I developed a few months ago. I still have a dent and the new lump that popped up slightly below were the original is keeps changing. The last time I reported it was soft, well it got hard, feels bigger on some days then smaller on others. I will keep a eye on it and report back in a month.

YYY good luck with your proceedure to day, I know you must be nervous but if it was anything like mine you have nothing to be worried about. The actual injections are a breeze. The must uncomfortable part will be the lipo which isn't all that bad either. It will be great to have your reports on your results to see if you have the same positive results I have had. Hopefully you will and this won't be another treatment that doesn't have a high percentage of success like all the other out.

yyy

Hey guys!

Just come back form the hospital. fortunately Stem cell injections were totally painless. The doctor reached the plaque by inserting the needle diagonally and not going directly into the plaque, to avoid any kind of issues. He told me these injections should give me some improvements,among which more elasticity in 3-4 weeks, but probably they could not be enough to markedly reduce the plaque and curvature. He said will do some PRP injections in March, I think directly into the plaque this time.
By the way, Last night I had a good erection wihout being on Cialis, let's hope it's a good sign.

Speak soon

op


yyy


LMP


yyy

At the end of Novembre I will have a follow-up and will ask if I can publish all the details

Sargonnas

Quote from: yyy on November 06, 2012, 04:25:28 PM
totally free thanks to national health service

No way. Does Italy work that way? Awesome!

yyy

rd,

How long did you wait to see the first results? I mean plaque decrease etc...Thank you

rd

It was within the 2-3 month range, the larger of the two treated lumps was gone. I did leave the area alone as much as possible as to not irritate it. Than it was almost a year eactly until I could say the remaining lump that was treated was fully gone. But I only had the one treatment. I would love to get others to maybe speed the process up but I couldn't/can't afford more at this point.

LMP


op



rd

Quote from: op on November 14, 2012, 08:09:38 AM
RD how much did you paid? :) & where you've done it?

I paid $5500.00 for the proceedure plus hotel and travel expenses. I live on the east coast so it total was around 6100 I think with plane ticket and hotel plus taxi service. I had it done through the California Stem Cell Treatment Center, they have two locations I scheduled before the second was open and traveled to palm springs california the first center to have my proceedure done.  


LMP


funnyfarm

I hope I am wrong but everything I have read about stem cell treatments commercially available today indicate they are a fraud which prey on the vulnerable.

For example:  Stem Cell Fraud: A 60 Minutes investigation - 60 Minutes - CBS News
When you are in tune with the unknown, the known is peaceful.

rd

Quote from: funnyfarm on November 29, 2012, 06:01:01 PM
I hope I am wrong but everything I have read about stem cell treatments commercially available today indicate they are a fraud which prey on the vulnerable.

For example:  Stem Cell Fraud: A 60 Minutes investigation - 60 Minutes - CBS News

I saw that as well before having my procedure but if you watch that there are some key differences from what I researched and experience. In the video the procedure was always done over sea's(Not in the USA). Also they promised you the world saying it would 100% cure you. They would also say you need more treatments if if it didn't work if I remember correctly. Where I went I was in the USA, they promised me nothing and said it was experimental. I did have results from one treatment, and when I asked about another they said to wait until I stopped seeing results. They didn't not try to talk me into anything they basically had the attitude of this is what we do and if you have any questions or are interested feel free to ask. The doctors were truthful and admitted they were still learning and just beginning to understand the process. The one in the video is def a scam, I don't believe all are especially the treatment center I went to.  

funnyfarm

Thank you for sharing your viewpoint RD, this is very helpful.  Maybe someday this will be a more mainstream option.

Also would love to hear from YYY regaring his progress.
When you are in tune with the unknown, the known is peaceful.

koolx

i have a suspicion that the user, yyy, really didnt get any stem cell treatment and may be lying. i say this cuz he hasnt been responsive to other ppl's questions here. the only one who's been responsive has been rd. i could be wrong and hope i am about yyy. but i'm following my hunches.

rd i got a question for you.. does having lumps, like you did, mean that you had peyronies?

funnyfarm

Also, RD are you satisfied with your results ?  And was the pain resolved or do you still have ongoing issues ?  thanks.
When you are in tune with the unknown, the known is peaceful.


rd

Quote from: koolx on December 03, 2012, 09:26:50 PM
i have a suspicion that the user, yyy, really didnt get any stem cell treatment and may be lying. i say this cuz he hasnt been responsive to other ppl's questions here. the only one who's been responsive has been rd. i could be wrong and hope i am about yyy. but i'm following my hunches.

rd i got a question for you.. does having lumps, like you did, mean that you had peyronies?

I went to 3 different urologist who confirmed my lumps as being peyronies. I was hoping it wasn't but all of them confirmed it. That's not including the urologist that did the stem cell injection and my GP.

rd

Quote from: funnyfarm on December 03, 2012, 09:44:40 PM
Also, RD are you satisfied with your results ?  And was the pain resolved or do you still have ongoing issues ?  thanks.

I'm not 100% satisfied as it isn't 100% resolved. When it is completely 100% gone I will be satisfied 100%. I still have a new lump right below were the original two that were treated were and another tiny one on the left side of my shaft the left one I only notice when I examine the area. I still have slight hour glassing and slight discomfort on the right side from the new lump but not as intense as before. What I would love to do is get another treatment on the remaining lumps and hope for the same result of a 2-3 month resolution to them but I don't have the money to do it right now. I was hoping that YYY would report back so we could compare results to make sure it was the procedure that actually got rid of the original lumps and to rule out it just being spontaneous which I don't believe it was.

james1947

Let's not be so hard on YYY.
He was last active November 22, he wrote he will be at the doctor by the end of November.
He didn't wrote nothing negative until now.
Maybe he is busy and this is the reason for not answering/updating?

James  
Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe ED.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

yyy

Hi guys

Not happy to come back and read those kind of comments...I'm not paid to publish here, just want to help everyone has you helped me with many info.
I was busy in this period, and also tried to "forget" my issue and wait to see any possible result.
To prove Im honest, I have to say at the moment I DID NOT have any kind of positive result... After the procedure the doctor told me It was an experimental treatment and He did not feel confident to inject directly inside the plaque (also because of the big needle), but only around it. I have to remind I have some "grafts" under the plaque due to a surgery (nesbit to remove a congenital curvature) so He didn't want to worsen my situation.
He also told me the next attempt will be a PRP injection directly into the plaque.
Next wednesday I will do a follow-up with him to book another procedure and to ask why I still have a little "remain" of fat tissue visible on my penis..in fact it seems the fat did not 100% dissolve

RD please tell me if you also had this kind of issue.

Speak soon

rd

YYY I didn't have any fat injected they separated the stem cells from the fat which took about a hour. I did however have what looked like swelling for a few months. I hesitate to call it swelling because it didn't hurt, and they injected a lot volume wise into my plaques which is while it took a few months for that all to go away or for the "swelling" look to disappear. I also had it injected into, around above and below the plaque, he also had to use a bigger gauge needle then he originally planned on because one of the plaques was to hard for the smaller needle to penetrate, I believe it was a 20 gaugle needle he ended up using. The doctor was most concerned with getting the stem cells inside the plaque that seemed most important to him from my perspective. Hope this helps, the area did feel different to the touch until after swelling look was gone.


james1947

yyy

So I am right :)
Every one can be busy and sometimes we need a break for thinking or working.
Wish you better results with the injection in the plaque.

James
Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe ED.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum

chefcasey

After 2 years of having this awful condition and trying everything else under the sun with no significant results, I've decided to give stem cell treatment a shot(no pun intended).  I contacted Dr. Lander after reading RD's posts and had a good 15 minute conversation with him.  I described my condition to him, and all the different uro's I've seen and everything I've tried.  My first impression was that he is a doctor that has a passion for this area and is very understanding and insightful.  He says his original intention was to  effectively reverse ed through stem cell injections, but hasn't had much success, but was surprised to see that he's having as much success with peyronies patients.  He quoted me $5500 for the procedure(the same as RD I believe).  He also says he wants to do a combination of stem cells and PRP as well.  As far as I understand He was only using it to treat ed, which I don't have, but is now using it in conjuction with stem cells for Peyronies Disease.  I'll be scheduling the injections for late January, and will be updating periodically with my results.  

funnyfarm

Excellent, will Dr Lander be your treating physician ?  He seems to have some pretty good credentials and was a professor of urology.  

Wishing you the best of luck !
When you are in tune with the unknown, the known is peaceful.

rd

Chef, that's the same price I was quoted and I got a cheaper prices I believe of 3500 if I needed a follow up. What is interesting is I only got stem cell's injected wasn't a combination of stem cells and prp. Interested in hearing your results with the added prp injections.

yyy

stem cells and PRP... I think it can be the key to improve our situation

chefcasey

Quote from: funnyfarm on December 31, 2012, 09:45:29 PM
Excellent, will Dr Lander be your treating physician ?  He seems to have some pretty good credentials and was a professor of urology.  

Wishing you the best of luck !

Thanks, yes Dr. Lander will be doing it on the 23rd of January.  I'm not expecting any miracles, but i really believe we're on the right track with regenerative medicine, not just for Peyronies Disease, but many other diseases as well.

rd and yyy:

I was also intrigued by the combination and perhaps prp contains different growth factors that better activate the stem cells.

Platelet-rich plasma: growth factors and pro- ... [J Periodontol. 2007] - PubMed - NCBI
http://www.biomet.com/biologics/international/print/cgf_abstract.pdf


koolx

Quote from: chefcasey on January 02, 2013, 05:36:51 PM
Thanks, yes Dr. Lander will be doing it on the 23rd of January.  I'm not expecting any miracles, but i really believe we're on the right track with regenerative medicine, not just for Peyronies Disease, but many other diseases as well.

I was also intrigued by the combination and perhaps prp contains different growth factors that better activate the stem cells.

hi chef. i'm thinking about seeing dr. landers also for my ED. he said stem cells havent been helpful for ED. but he suggested a combo of stem cells and prp for me. maybe it'll work. do u know if this combo has helped stem cells combat ED or other conditions better than without prp?

chefcasey

koolx:

I haven't seen too much written about the combination of both of them.  I do know however prp has been successful on it's own when used particularly for knee and shoulder injuries especially with tendonitis.  My best understanding of the process is that stem cells by themselves are not well activated, meaning they contain the essential building blocks to grow new tissue, but without direction to order them what to do, they don't have much effect.  Prp is rich in growth factors for soft and hard tissues as well smooth muscle and cardiac tissue.  In theory these growth factors can act as the activators for the stem cells. perhaps someone can correct me if I'm wrong, but I believe that's the theory behind combining them. I understand it's still highly experimental, but at this stage in the game there isn't much else on the horizon, so to me it's worth the risk if you can afford the procedure.


koolx

Quote from: chefcasey on January 09, 2013, 05:28:59 PM
koolx:

I haven't seen too much written about the combination of both of them.  I do know however prp has been successful on it's own when used particularly for knee and shoulder injuries especially with tendonitis.  My best understanding of the process is that stem cells by themselves are not well activated, meaning they contain the essential building blocks to grow new tissue, but without direction to order them what to do, they don't have much effect.  Prp is rich in growth factors for soft and hard tissues as well smooth muscle and cardiac tissue.  In theory these growth factors can act as the activators for the stem cells. perhaps someone can correct me if I'm wrong, but I believe that's the theory behind combining them. I understand it's still highly experimental, but at this stage in the game there isn't much else on the horizon, so to me it's worth the risk if you can afford the procedure.

hi chef.. do u know if stem cell treatment and prp can pose risks to the penis? as i said, i'm thinking about getting this combo treatment. but do u know if there are risks or will it make me more impotent?

koolx

Quote from: chefcasey on January 02, 2013, 05:36:51 PM
Thanks, yes Dr. Lander will be doing it on the 23rd of January.  I'm not expecting any miracles, but i really believe we're on the right track with regenerative medicine, not just for Peyronies Disease, but many other diseases as well.

hey chef i wish u lots of luck for ur sc treatment on the 23rd.. i know everything will go well for u.

chefcasey

koolx:

thanks, I got the appointment set for the 22nd now, so I'll be leaving tomorrow.  From what I've read and from speaking with the doctor, there are no real risks with these types of injections, other than the actual puncture from the needle, which is why you would want a trained urologist like Dr. Lander.  Since the stem cells are adult and are your own, and the blood drawn to to separate the prp is your own, there is no risk when it is injected into your penis.  The same types of procedures are being done on all sorts of tissue injuries especially in sports lately.  I guess you could say there is a risk as well in the wallet, as it isn't cheap, so you may be out 5500 with no results.  

If you research prp and stem cell therapy, you'll find mixed results, but I believe this is from improper use.  Some doctors are using it for everything under the sun including "anti-aging" like facelifts.  Really the goal is to mimic the healing process at an injury site but much quicker and with much more resources (because of the concentration of growth factors).  So for conditions with chronic inflammation and pain in soft tissues like tendonitis and joint pain(I believe tiger woods had some done on his achilles) it seems to have a decent record.  Thats why it seems to me it would work well with peyronies disease(2 years in and still in pain daily).  

Sargonnas

Chefcasey I wish you all the luck with this procedure and I will be looking forward to read improvement reports from you.  ;)

A note about needles and the penis. I got the other week my hard flaccid penis pinched TWICE by a tiny insulin needle to administer Caverject to it (the doctor wanted to make an erected examination) Although the experience was clearly a torture and the nurse had to gave up because I even bled a bit I got NO pain afterwards or any sudden worsening. So if the syringe its small and its done well it shouldnt give problems.  

koolx

Quote from: Sargonnas on January 20, 2013, 01:10:36 PM
I got the other week my hard flaccid penis pinched TWICE by a tiny insulin needle to administer Caverject to it (the doctor wanted to make an erected examination) Although the experience was clearly a torture and the nurse had to gave up because I even bled a bit I got NO pain afterwards or any sudden worsening. So if the syringe its small and its done well it shouldnt give problems.

i want to add smthing.. be careful with needles. just cuz u didnt feel any pain and probly never will doesnt mean its safe. using needles can and will result in a bent penis. eventually, theyll result in total erectile dysfunction.

and what exam did they perform on u?

koolx

Quote from: chefcasey on January 20, 2013, 12:34:57 PM
koolx:

If you research prp and stem cell therapy, you'll find mixed results, but I believe this is from improper use.  Some doctors are using it for everything under the sun including "anti-aging" like facelifts.  Really the goal is to mimic the healing process at an injury site but much quicker and with much more resources (because of the concentration of growth factors).  So for conditions with chronic inflammation and pain in soft tissues like tendonitis and joint pain(I believe tiger woods had some done on his achilles) it seems to have a decent record.  Thats why it seems to me it would work well with peyronies disease(2 years in and still in pain daily).

hey chef.. so todays the day? sounds good.. you'll be ok.

i talked to dr. lander about the combo of stem cells with prp in treating ED. he said it hasnt been that succesful with ED. but since the nature of my ED is unique, he said he doesnt know what the outcome may be. so theres a chance it could work. my ED came about from a medication that i took which resulted in a lot of pain and dysfunction. it made the base of my penis look like an hour glass shape. so technically i consider this a phy injury of sorts. so hopefully this combo thats used in healing phy injuries will heal me.

good luck chef.. youre in my prayers.  

Sargonnas

Yeah koolx I was just trying to lie to myself but I know perfectly it was the dumbest thing to let the nurse and doctor do that to me. Shame on them, really, although its my responsability as well. I prefer to think it didnt worsen my condition. I cannot believe my luck, its unreal. Anyway, two guys got injections of stem cells here and they only improved so thats why I say one injection with a small needle shouldnt be a problem.

The doctor just wanted to see the huge vein-like bumps I have in erection.

chefcasey

Thanks for your encouragement guys:

I just got done with the procedure and am back at my hotel.  Overall I'm pleased with how it went.  They harvested the stem cells and prp first.  I have low body fat so it took some doing to get the stem cells from liposuction.  Dr. Lander says that skinnier guys do have a higher concentration of stem cells for some reason and confirmed it, I can't remember the exact number but mine were in the millions which he said was high.   It was pretty uncomfortable, but not painful, feeling the fat getting pulled out of you.  

The actual injections were much less noticeable.  I didn't even feel anything past the initial numbing injection.  I also didn't look where he was injecting exactly as I can't stand to look at my penis getting poked with a needle, but he said he made a lot of passes through the plaque, as he used the swiss cheesing effect. He says he got at least 50 passes so he hit it really well.  Overall the staff was very friendly and professional.

So now time will tell if it helps or not.  I asked him if my lifestyle habits like diet and exercise will have any effect on the way the stem cells respond and he said no, but I'm still going to eat right and exercise right just to be on the safe side.  

Just wanted to update a little.  I am really tired and going to get some rest as I'm going to be sore for a few days.  

funnyfarm

Thank you for the detailed report.  I really hope this works out for you Chef !
When you are in tune with the unknown, the known is peaceful.

koolx

Quote from: chefcasey on January 22, 2013, 09:28:49 PM
Thanks for your encouragement guys:

So now time will tell if it helps or not.  

chef youll be fine.. give us an update soon. i'm sure it'll be a positive one.

koolx

Quote from: Sargonnas on January 22, 2013, 07:00:54 AM
Yeah koolx I was just trying to lie to myself but I know perfectly it was the dumbest thing to let the nurse and doctor do that to me. Shame on them, really, although its my responsability as well. I prefer to think it didnt worsen my condition. I cannot believe my luck, its unreal. Anyway, two guys got injections of stem cells here and they only improved so thats why I say one injection with a small needle shouldnt be a problem.

hey sargonnas! how are you? so you got stem cell treatment for your ED or peyronies? you also mentioned that 2 other men also got stem cell treatment at the same clinic you got it from.. did these men have ED or peyronies?

Sargonnas

LOL no I wish koolx I was talking about the guys on this thread.