Peyronies Society Forums

Peyronies Disease TREATMENT Discussion Boards => Alternative Treatments of Peyronie's Disease => Topic started by: Joshua on August 17, 2005, 08:13:05 PM

Title: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Joshua on August 17, 2005, 08:13:05 PM
DMSO and DMSO based solutions are discussed here.
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:42:08 AM
Posted: Sun Jun 26, 2005 3:03 pm     
 
Joshua


 I am betting many will disagree with me here. However, I will admit I think DMSO has a place in Peyronies Disease treatment. There is very good information on the net explaining its positive effects on fibrosis, reducing the swelling in tissue and of course its skin penetrating abilities.
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:42:35 AM
Posted: Sun Jun 26, 2005 3:40 pm     
 


 Joshua wrote:
I am betting many will disagree with me here. However, I will admit I think DMSO has a place in Peyronies Disease treatment. 


I would agree with that Joshua. I have used it on animals (specifically birds of prey). To tansport other substances to infected areas with little blood supply. Its penetrating power is remarkable. As you point out, in addition to its transport power it is an antii-inflamitory.

PDFTD knows a considerable amount about DMSO. M UK and some others may as well.
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:43:01 AM
Posted: Mon Jun 27, 2005 3:36 am     
 
Guest

 It's dcaptain (sorry, I'll email you Hawkman about this, but just wanted to post again first). For those of us not in the know, what's DSMO?

Thanks.
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:43:24 AM
Posted: Mon Jun 27, 2005 4:21 am     
 
Joshua

 dcaptain:
I hope pdftd chimes in or rzz. I suggest you google it. You can even google it with peyronie's. The very basic answer is it is an anti-inflamatory that can be applied to the skin. It is very popular for arthritis in Russia. There are some great threads about dmso on the bio forum under home remedy treatment. I think it helps and I am looking at it for possible use.

P.S dcaptain thanks for supporting the forum!!!!!!!
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:43:49 AM
Posted: Sun Jul 03, 2005 1:53 am     
 
Joshua

 This is a touchy subject I know. However, the fact remains that the “home remedy” thread remains the largest thread on Biospecifics. I found that thread full of information and a fascinating read. I was impressed with the work/research that many members put into the formula. Whether it worked or not it was incredible how everyone involved shared research and testimonials on their own progress or lack of. I also must comment that you will find more reported success stories on that thread than any other thread in all the years that Biospecifics has been up. That is a fact. I can’t say the successes are real, hoaxes, or in the mind. However, I can count dozens of men reporting what they felt was success. Unfortunately, you can’t point me into the direction of any other thread with reports like that. Rzz and Pdftd shared fascinating and powerful theories that showed how that mysterious formula might have possibly worked for some. I strongly recommend any Peyronies Disease suffer to read those threads ( home remedy 1 and 2) on Biospecifics. I am not saying it works or not, However, I promise you will find the threads interesting and informative!
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:44:13 AM
Posted: Sun Jul 03, 2005 8:40 pm     
 
j

 I think the thread is long because so many guys got interested and tried it, and that in turn was because the initial post by "Thacker" seemed credible. Unfortunately no more was heard from "Thacker", which tended to discredit the story.

There does not seem to be any scientifc basis for the use of DMSO and ACV against Peyronie's. Several guys claimed early success, but as time went on I heard fewer and fewer positive reports. Eventually interest seemed to die out. My own conclusion is that it was all just a hoax.
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:44:40 AM
Posted: Thu Jul 07, 2005 12:31 am     
 
Joshua


 I don’t think it was or is a cure but I would not be so quick to dismiss this formula all together. I have read many papers on DMSO. It is being used in hospitals to reduce brain swelling for head injuries here in America. It is the number one treatment for arthritis in Russia. There is an interesting study where cells from a Peyronies Disease plaque were placed in dmso and they died off while the non Peyronies Disease infected attached tissue remained healthy. I know it was listed in the patent for one of the verapamil applications. I have read where it can reduce the swelling from a twisted ankle in minutes. There is plenty of evidence to prove it drive chemicals deeper into the tissue than any other substance available. There is a chance it was driving this apple cider into the plaques. I THINK hardened plaques/calcified MAY have been helped. I do not think it worked for non calcified plaques. I think that is what caused it to die down. These are just my wild theories. I know pdftd has much more information and knowledge about this subject than I. I understand he talked personally with the family of the Dr that suggested this treatment. I understand he went in depth with this research and found the story credible. A very fascinating subject we should not just blow off as a hoax. There is too much to show it COULD be more than just that. Discussion can’t hurt!
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:45:05 AM
Posted: Fri Jul 08, 2005 4:31 am     
 
PDFTD


 Hi All,
First allow me to apologize for not addressing the DMSO issue for so long. I am Deeply involved in a personal project and my time goes to it. However it seems as though there is much for me to say based on the posts on this forum. So I will do my best to cover everything I can and answer questions in the interim. With my schedule so busy I will have to attend to this subject in more then one post.

I have taken three posts from the forum that I will first use as a starting point to my clarification of DMSO, the Thacker Formula and how they are relative.

Kindly read the post by J, on Jul 03, 2005. In response to j’s post I can say that the Thacker Formula was and is not a hoax by any means. Thacker (His last name), was immediately verbally attacked following his first post. This verbal abuse took place at every attempt that he made to post, so he stopped. This should be easily understandable as nobody wants to be the victim of verbal abuse, more especially since he came to the forum with honorable intentions. J, you say there is no scientific evidence that the Thacker Formula had efficacy. On the contrary, the formula was created and tested by Thacker’s Grandfather, the late Doctor Thacker. Doctor Thacker had Peyronies Disease, all of his sons had it, and their sons had it as well. (A good indicator corresponding to the common Medical communities justification that Peyronies Disease is a Genetic disease). In fact Doctor Thacker treated Hundreds of his own patients who had Peyronies Disease with his formula and as Thacker told me, the rate of efficacy was in the 90% range. Is that outrageous? I don’t think so IMHO. I justify my opinion simply because most Doctors will not consider any treatment that “Has no basis in science”. To that I say, “horse pucky”.

To reply to your statement that the Thacker Formula died out let me say this. I counseled, off forum, dozens of men in the use of this formula and it is my conclusion based on what was reported by members of the BTC forum and the men I spoke with one on one that The Thacker formula is Efficacious. Just to retort a possible thought that you may be harboring, these men I worked with off forum, did so because they did not want to be subjected to the ridicule and foolish remarks that were stated on the forum to those who reported their use on forum and got attacked and called liars.

I will close out this part of my discussion saying this. A week ago a man who shall remain nameless contacted me. He stated that he had read my posts that dated back to 2004 and wanted to know if I would help him get started on the Thacker formula ASAP. He started the formula two days ago and I am working with him very closely one on one. The Thacker Formula is not dead, forgotten nor a Hoax.

I’ve much more to say on the subject but I need to go for now and will return with additional information for you and everyone to review.

Regards,
Barry
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:45:25 AM
Posted: Fri Jul 08, 2005 5:35 am     
 
Joshua


 pdftd:
Thanks for the posts and information. I was hoping you would interject but I did not want to push you.
Barry with your permission, I would like to repost the final formula you and Thacker finalized.

Also, what is your opinion of my hypothesis that the formula works better on a hardened calcified plaque?
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:46:29 AM
Posted: Fri Jul 08, 2005 8:02 pm     
 
j
Voting Member


 PDFTD, maybe you would agree that it's hard to accept claims of success for a therapy developed by a Dr. who's identity can't be revealed, whose records are not available, and who apparently proposed no mechanism of action to explain why this formula should work. It's an appealing story, but not nearly enough to get me to try this therapy - which is tedious, bad-smelling and - in my opinion - possibly dangerous, given the ability of DMSO to carry almost any sort of contamination or foreign substance deep into tissues and the bloodstream.

I only recall a couple of actual posts by "Thacker" - correct me if I'm wrong. Most of the ridicule was directed at him after he stopped posting. It just seemed extremely odd for someone to drop a bombshell post like that, then refuse to substantiate, elaborate or even discuss it further on the forum. Not to mention annoying to have a cure dangled in front of us, mirage-like.

If you are sincere about this and believe guys have actually benefitted from it, I appreciate that - but from the point of view of an objective outsider there's just nothing to go on.

I'd welcome more information from you on this. But as it stands now it's the Loch Ness Monster of Peyronies Disease therapies.
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:46:54 AM
Posted: Sat Jul 09, 2005 4:11 am     
 
Joshua

 j wrote:
PDFTD, maybe you would agree that it's hard to accept claims of success for a therapy developed by a Dr. who's identity can't be revealed, whose records are not available, and who apparently proposed no mechanism of action to explain why this formula should work. It's an appealing story, but not nearly enough to get me to try this therapy - which is tedious, bad-smelling and - in my opinion - possibly dangerous, given the ability of DMSO to carry almost any sort of contamination or foreign substance deep into tissues and the bloodstream.

I only recall a couple of actual posts by "Thacker" - correct me if I'm wrong. Most of the ridicule was directed at him after he stopped posting. It just seemed extremely odd for someone to drop a bombshell post like that, then refuse to substantiate, elaborate or even discuss it further on the forum. Not to mention annoying to have a cure dangled in front of us, mirage-like.

If you are sincere about this and believe guys have actually benefitted from it, I appreciate that - but from the point of view of an objective outsider there's just nothing to go on.

I'd welcome more information from you on this. But as it stands now it's the Loch Ness Monster of Peyronies Disease therapies.


J,
I very respectfully disagree with some of your post. Thacker was absolutely attacked instantly and in ridiculous fashion the second he posted the formula and attempted to answer questions. Seriously, review the beginning of the first thread. You know how crazy it can get on Bios forum. Again, I would agree with you but if you do some research you can at least see some correlation to the dmso fighting Peyronies Disease. I am saying its possible. If you review the research material on dmso alone you could see that it’s possible that this could help. The fact remains that the threads which is a thousand post long! Has more reports of success than any other thread on Peyronies Disease on any other forum on the net. That is not to say it is real or works but it shows that there might be something to it. I can understand men going underground to use the product now. They were starting to get ridiculed from others and stopped reporting. I wished that did not happen. We should support men that wish to pursue alternative treatments, even if we don't agree with them. They need and deserve our support and respect!
Take a read on the net about dmso with an open mind. You might be suprised at what you find-I was
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:47:16 AM
Posted: Sat Jul 09, 2005 2:49 pm     
 
Hawkman

 Here is a link that supplies significant information on DMSO by one writer referencing many studies. I think that anyone that does not mind reading, will find it very interesting. I found the collagen and autoimmune issues especially interesting especially since Peyronie's Disease is not mentioned in the article. To any newcomers, an advantage of this forum is that all you have to do is click on the link below to see the article.

http://www.dmso.org/articles/information/muir.htm

As stated before on this forum or elsewhere, I have used DMSO in veterinary applications to transport antibiotics to areas with too little blood supply for reliable transport of injectable antibiotics which I also administered. This has namely been the feet of birds of prey that are very susceptible to fatal infections that seldom respond to any injectable, oral, or topical antibiotics. DMSO solution is a confirmed best treatment by veterinary experts at the University of Michigan and the worlds leading veterinary researchers on birds of prey. I marveled at how quickly it penetrated my own skin and the quick taste/odor that resulted. This gave me strong concerns about contaminant transport and made me very careful to wash my hands prior to use and to avoid contact with DMSO based solutions. I do admit to experimenting a bit with plain DMSO long before I had Peyronies Disease.

I am intrigued by DMSO but keep a healthy skepticism of every current conventional and non-conventional Peyronies Disease treatment. I hope the article is interesting to forum members that have not already researched this topic to the point of exhaustion.
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:47:56 AM
PDFTD
Voting Member
 
 
Joined: 21 Jun 2005
Posts: 12
Location: Texas


 I am re-posting so the post will come up with MY name and not Guest. This is at the request of a fellow member. Somehow I disconnected myself accidentially and the poster became Guest.

j wrote:Quote:

PDFTD, maybe you would agree that it's hard to accept claims of success for a therapy developed by a Dr. who's identity can't be revealed, whose records are not available, and who apparently proposed no mechanism of action to explain why this formula should work. It's an appealing story, but not nearly enough to get me to try this therapy - which is tedious, bad-smelling and - in my opinion - possibly dangerous, given the ability of DMSO to carry almost any sort of contamination or foreign substance deep into tissues and the bloodstream.

I only recall a couple of actual posts by "Thacker" - correct me if I'm wrong. Most of the ridicule was directed at him after he stopped posting. It just seemed extremely odd for someone to drop a bombshell post like that, then refuse to substantiate, elaborate or even discuss it further on the forum. Not to mention annoying to have a cure dangled in front of us, mirage-like.

If you are sincere about this and believe guys have actually benefitted from it, I appreciate that - but from the point of view of an objective outsider there's just nothing to go on.

I'd welcome more information from you on this. But as it stands now it's the Loch Ness Monster of Peyronies Disease therapies. 


J,
I would agree if: I had not had so may conversations with Thacker personally.I will agree that it is an appealing story. I will elaborate on that statement,The use of the words "appealing story" indicates that what I have said so far is just that, a STORY. I would hope that if I make a statement of fact that it is believed and not called a story. otherwise the implication is that I am not being truthful in my words. I STRONGLY suggest that you re-read my post and concentrate on the section that says that I worked off forum with dozens of men using the Thacker and why. If at that point you still call my post a story then you are basically calling me a liar. I most sincerely hope that you don't come to that conclusion.

Furthermore, I have knowledge of DMSO that you cannot read in a book, so information on DMSO is limited to what you can read on your computer screen. You claim to be an "objective outsider", my contention is that your manner of thought and/or use of words do not dis-credit or challenge me as a truthful and honorable man. I promised in the last post to continue further posts about DMSO and the Thacker Formula which in fact I will do as time allows it. In the meantime please refrain from insuiating(sp) that I am other then truthful and honest.

Barry/PDFTD
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:49:26 AM
Posted: Mon Jul 11, 2005 12:27 pm     
 
Hawkman


 Barry,

Are you and RZZ in agreement on what constitutes the Thacker Formula, and would you post the formula here? I am interested in whether pure/uncut DMSO is cut to 70% by adding 20% organic apple cider vinegar and 10% castor oil. Or, do you start with DMSO that has already been cut to 70% with sterile water? It seems the first would be correct.

In addition, have you used this? Do you have a summary of your opinion on its merits and limitations? Is this conclusion from personal results or the reported results of others, or a combination?

I understand you are not a doctor and it is only your opinion I am soliciting. I am not asking for conclusive double blind studies. Hell, we can't get that for the treatments being offered by the "top Peyronies Disease Docs”that have universities and medical companies behind them.

I am also very interested in hearing RZZ's final assessment and opinion since I have read all of "home remedies 1".

I am interested in a clear easy to understand post of the formula, how many men you KNOW have properly used it, and their reported results. As we all know, we have to be suspicious of posts on some other forums because we are never sure if we are reading an imposter or the real deal.

It would be great to have that information in one clear post for newcomers to evaluate on a forum where we can trust the identity of the source.
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:50:10 AM
 PDFTD

 Hawkman,
Yes rzz and I are in total agreement on the mixture. The DMSO should be Pharmaceutical Grade, which can be purchased on the net. The DMSO should be uncut at 100% as you indicated. I am going to post an additional post following this post with the entire procedure for the Thacker formula.

No I have not used it as a primary treatment because I had already started another treatment that was working very well and felt no need to use two therapies.

You ask for a summary! That will be easy to answer. The Thacker formula is an Alternative Peyronies Disease treatment that has been tested by dozens of men. all of whom reported their result either on the BTC forum or to me directly. As stated in an earlier post this was over a period of approx. two years.
Of those men with whom I worked with off forum, one on one, I can comfortably say that the efficacy was around 90% or in other words, 9 out of 10. In addition with that having been said, each individual saw at least a 50% improvement overall. Of those on the forum it is a bit difficult to put them into the same category because many men modified the formula on their own or just used the DMSO. Credible results cannot be reasonably attained when the formula is not used properly and the men reporting their result are nameless and may be reporting untrue results. My test group was about 80 plus men.

Correct as you are, I am not a Doctor. But, the above information is not based on conjecture or opinion it is factual and accurate.

I cannot speak for rzz on this matter with the exception that we agreed on the mixture of 70%--20%--10%. I do know however that he used the formula and has efficacious results. To what degree would be impossible to say because he never told me. I would suggest that you contact him personally for that information. I hope I satisfied your questions and curiosities. I’ll post the formula next on another post as promised.

Best,
Barry/PDFTD
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:51:12 AM
Posted: Tue Jul 12, 2005 1:43 am      
 
PDFTD


 Thacker Formula-Revised…07/11/05

An Informational,

My communications with Thacker confirmed much of what was believed from the little information initially given. The discussions covered the following, Thackers use and results of his Grandfathers Formula…..Doctor Thacker, Thacker stated that Peyronies Disease starting with Doctor Thacker, who suffered from Peyronies Disease, as well as his uncles, father and himself. It seems to indicate in theory that Thackers family from his Grandfather to himself had a Genetic Pre-Disposition to this disease. Thacker indicated to me that DMSO and its quality was of the utmost importance, as expressed to him by Doctor Thacker and clarified many times. Unfortunatly, the source of Doctor Thackers DMSO is unknown. This does not negate the other two ingredients in any way and their importance to the formula. Thacker confirmed the 70%-20%-10% mixture as what was used by him. Thacker did stress that a high quality Apple Cider Vinegar be used, I told him that many men were using organic ACV and he did not agree nor disagree, but additional research indicated and confirmed that Organic ACV should be used. Castor Oil is generic in nature, so any brand will do. Thacker said that his Grandfather used the formula on men with Dupuytrens Contracture, aka (DC), he did not mention results, but it was used never the less.

Taking nothing from Thacker, it must be understood that he was for the most part a “user” of this formula, and did not in fact know much as to what the components did or why. His Grandfather mixed it for him; Doctor Thacker pre-mixed the formula, and gave it to him as needed with instructions on how to apply it.



I suggest strict self-obedience with the treatment and trust that it will work. It takes some time.
You must keep the wrap soaked during application.
The garlic odor from the application could be bathed off and a scented cream such as Aloe Vera applied to the penis after application, but the internal odor that omits through the skin pores and breath, is something you have to live with, and I can only suggest strong breath mints and wear cologne to envelop the smell. That will usually cover it. My own personal research has concluded that gently massaging the plaque after application is acceptable as long as it does not incur pain. Do this for about five-ten minutes.


THE FOLLOWING IS A DIRECT QUOTE FROM THACKER TO ME

QUOTE
“I usually followed my evening application with a hot bath and massaged the plaque forcefully but not painfully. It took about three to four months for me to start seeing results and then positive results started coming quickly. The hard nodules will suddenly start getting soft. They may break apart. Once that starts happening things improve fast. You should realize increased erection quality right off the bat. The DMSO
will smooth the muscle in the penis.”
“Once the hard nodules start getting soft or breaking up into bits. It took about six more months of application and message to finish it off. My penis then healed almost back to pre-Peyronies Disease. I would say that I am 90% where I was. I no longer have any hard pieces of plaque in my penis. I have one small indentation left where a huge piece of plaque was that did not heal all the way back. The curve will reduce slowly as plaque resolves. I started with a 50 degree curve when it was at its worse, and now, no noticeable curve”
END QUOTE


Mixing Procedure,

You MUST, wash your hands with any type of hand or body soap prior to the mixing process.
The formula CAN be premixed. How many days in advance were not discussed with Thacker but all indications lead to 3-5 days. The premixed batch must be sealed when not in use and kept at room temperature. (DO NOT refrigerate premixed batches). The formula is comprised of 70%DMSO-20%Apple Cider Vinegar-10%Castor OIL. In order to mix the formula use three separate 10cc syringes and draw the liquid up to the 1, 2, or 7 mark depending on the liquid. Then squirt each one into a small glass bowl and mix well with an eyedropper.


Application Method.

Warm the formula prior to use; this should be common to its application. Soak the mixture on a flannel sheet of cloth (NO coloring, MUST be white) or an appropriately sized strip of sterilized gauze. Wrap the cloth completely around the penis, then to hold it in place use white medical tape or uncolored string. Do this application once daily (the evening hours would be preferable to most), and as consistently as possible through the week. The duration in time should not be less then 1/2 hour, although 1-2 hours is favored. DO NOT refrigerate pre- mixed batches, if you do, throw that batch away. Also, if you get redness or blistering, discontinue use and apply Diaper Rash Medicine to ease the problem and correct it. Aloe Vera is appropriate as well. Once corrected continue treatment.


CAUTION!
DMSO is a very safe solvent to use in this formula but……………….
While the bottle is open and/or the batch is being pre-mixed be very cautious and not get it into you eyes. If you do go the nearest E.R, they will know how to treat you with an eyewash.
Also, pure DMSO is not to be taken internally. The same conditions apply as to the above remedy.

DMSO is a very powerful delivery agent, meaning that it will put into your body anything on your hands, so it MUST be used under Sterile Conditions.


DMSO on line Purchase Sites,

www.webvitamin.com Natures gift
www.lifesvigor.com Natures Gift
www.herbalremedies com Clinic Service Co.
www.kornax.com Rich’s



The creators of this formula are not Doctors and do not profess to be, we are however, researchers and bring this treatment to you with no promise of efficacy but, but most assuredly a sparkle of hope.
This formula is an ALTERNATIVE, non-Medicinal treatment. Years of research, in the aggregate, have been invested by myself and another Peyronies Disease survivor who’s research efforts played a solid role in putting this formula together for all Peyronies Disease sufferers to try. Your Doctors may attempt to convince you that the use of this treatment is flippant; the ultimate decision to use this treatment is up to you. The general statement Doctors use is, “it has no basis in science”, to that I say, tell that to the many men who have had efficacious results. Also, there are NO RX contraindications to this formula and it’s not invasive. Used as directed, it is as dangerous as taking an aspirin.


Good Luck,
Barry, aka, PDFTD, Peyronies Disease Survivor for 8 years
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:52:27 AM
Posted: Fri Jul 15, 2005 4:08 am     
 
Caspian


 Hawkman wrote:
I marveled at how quickly it penetrated my own skin and the quick taste/odor that resulted. This gave me strong concerns about contaminant transport and made me very careful to wash my hands prior to use and to avoid contact with DMSO based solutions..


Life Extension scientists Durk Pearson and Sandy Shaw talked about DMSO decades ago and were cautioning people to be very careful not to have any contaminants present because they would pass right on through. They also said that DMSO worked largely as a powerful antioxidant and that it broke down these primary free radicals into secondary free radicals that were less harmful. They recommended using a broad spectrum antioxidant along with DMSO to take care of the secondary radicals.
 

_________________
You are what you iz
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:52:53 AM
Posted: Sat Jul 16, 2005 7:48 pm     
 
Joshua


 Pdftd:
THANKS SO MUCH FOR THE POST ON THACKERS! My own situation has improved to the point I am currently not requiring any treatment beyond supplement maintenance for hopeful prevention of the symptoms returning. However, if a descent size plaque nodule would return I would try this formula. I have read enough about it to conclude it is safe, cheap and has the potential to work. I take vitamin e for the same reasons so I see no reason not to follow that thought process with this treatment.

A couple of questions:

1. My own individual research on this treatment makes me wonder if it would not be more beneficial to calcified late stage Peyronies Disease plaques. Your thoughts…
2. Do you still communicate with Thacker’s grandson and are there discussions on making his widely discussed journal available? That would be fascinating reading and allow us to get into his reasoning of why this mixture may work.

Thanks for your brilliant post. This subject is fascinating and shows the true spirit and strength of these forums/discussions!
Joshua
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:53:18 AM
Posted: Sun Jul 17, 2005 2:21 am     
 
PDFTD

 First let me say your very welcome. Something that you might find interesting, I found and started expiermenting with DMSO over two years prior to Thacker writing his first post. So I had a good working knowledge of DMSO already. I can't emphasize enough that DMSO is safe as long as used with caution and common sence.

A tid bit of info: DMSO will carry, transdermally, (through the skin) anything that has a molecular weight of less then 1000. So the general thougth that DMSO will cause ANYTHING to penetrate the skin only applies under the above conditions.

Joshua, to answer your question about late stage Peyronies Disease I can say from personal knowledge that if this formula is going to have efficacy, it doesn't matter what stage your in or how long you have had it.

Thackers Grandson and I had many conversations, but he is a private man and when our conversations of Dr. Thacker's formula were done he stopped responding to my e-mails. I have no explaination for that, it's just the way it happened. As far as the Journals go, they are no longer available to me.

Just a closing statement before I say bye: Millions of people drink Coca Cola every day without a second thought.............BUT, that stuff will eat rust off metal and if you get it in your eyes it will burn.

Just something to think about!!!!!!!

Best,
Barry/PDFTD
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:53:39 AM
Posted: Mon Jul 18, 2005 12:01 am     
 
Joshua

 Any guess: would l-arginine and dmso mixed produce any results? I have read that l-arginine is mixed into some foot rub creams for diabetics to encourage blood flow into the feet. I wonder would l-arginine mixed with dmso penetrate the skin and cause blood flow in the penis. Also, remember the exciting studies showing that arginine might help Peyronies Disease.
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:54:03 AM
Posted: Mon Jul 18, 2005 4:20 am     
 
PDFTD

 Joshua,
To answer your question,yes DMSO will carry it with no effort. L-Arginine has a molecular weight of 174 and is positive charged. But it has never been tested as a compound so I would not attempt doing it. There are to many factors that I have to consider before I could give it any approval as safe and/or effective.It would take months to test your theory Joshua.For more info go to this site and look around.

I have created and/or revised two treatments, Thacker formula and the S/I formula. Concurrently I put about 2 1/2 years research and study into these treatments before I would give them any on forum endorcement.I alone was the guinea pig.

biomedia.bio.purdue.edu/IML/Amino/html/arg.html

Best,
Barry
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:54:26 AM
Posted: Sat Jul 23, 2005 2:55 pm     
 
Joshua


 Rzz:
Yes, you are absolutely correct; Pdftd has answered my questions quite thoroughly. His knowledge on DMSO is incredible. I wanted you to also chime in on my theory that if this formula works it seems like it would help the late stage calcified plagues more than soft or new plaque growth. The testimonials of it working (BTC Home Remedy threads) always seemed to indicate it breaks up or splits hard plaques. The research on the ingredients indicates to me it would only have impact on a calcified plaque. Your thoughts?

My own condition has thankfully improved dramatically. However, I am left with one very small piece of stubborn plaque. It is soft not calcified. I do not wish to try the formula yet without more research.
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:57:32 AM
Posted: Sun Jul 24, 2005 11:49 pm      
 
Hawkman


 Rzz,

I am interested in your assessment of the Thacker formula on a personal level. Did it help? How sure are you that it was the formula that helped and not the natural reversal of the disease? Don't hesitate to make your response as long as you like. I am also interested in it's effects on erection whether good or bad. Conventional medicine seems to have nothing to offer me so I am quite interested.

Thanks in advance.
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:58:14 AM
Posted: Wed Jul 27, 2005 1:54 am     
 
JUAN

 Hi there,
I am very interested in this dmso. My boyfriend and i have just about given up hope however all the talk seems tobe around this disease just developing. Would this treatment help for Peyronies Disease caused through trauma?
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:58:47 AM
Posted: Thu Jul 28, 2005 8:59 pm     
 
PDFTD

 Juan,
The answer would be yes. I could get into all the reasons why but, then I would have to compose a post three pages long.

Understand though that because this treatment is similar to any other treatment,RX or Alternative, in that some work and some don't, you should keep that in mind if you choose to use it. Good Luck and if you need my help any more I would be more then glad to respond.

Regards,
Barry/PDFTD

Peyronies Disease Victim for over 8 years
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:59:22 AM
Posted: Sat Aug 06, 2005 7:56 am     
 
Rzz

 Hawkman,

You ask how the formula worked for me and how I was sure it was the formula and not just natural reversal. I'll adress the second part first.

1) I can not be 100% it was not natural reversal, but I tend to doubt it because my Peyronies Disease was well over 4 years old when I started it and Peyronies Disease reversal at such a late stage is very, very rare.
2) I began to see some improvement within weeks of starting the formula. I would ocassionally have to take breaks from the formula because my skin would become sensitive to it. When I would do so, I would see the improvement stop. When I would start back up the slight improvement would begin again.

So there is no way I can say it was not natural reversal, but as you can see, it would be quite a coincidence if it were. However, maybe the formula allows the natural procees to work, but this is something for futher research and I've got my hands full on other research of the formula right now. Strange thing about research; it seems like the more answers one finds, the more questions he creates.

As to what degree it helped me. First let me say that I've stated many times before my problem was never really curvature. Yes I had some curvature at the begining, but it was not bad. Mt problem was erection quality. At first it was OK, but as time went by, I became about 75%-80% impotent. This in turn caused MAJOR depression. I would say the formula after about 6 months of use improved my erection quality by about 25%-30%. I began to get night time erections and morning erections which I had stopped getting altogether. So I was and still am about 50% impotent. Now 50% is still poor and sex is difficult, but possible. So to be at the stage I was at and have that kind of improvement was just fine by me. However, for some reason the formula just seemd to stop working. I have some theories about this and some ideas that I'm going to try. But right now I'm getting a little tired and I'll finish this up tomorrow. There is some good news and some bad news. Unilt tomorrow. Rzz
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 12:59:44 AM
Posted: Sun Aug 07, 2005 6:34 am     
 
Rzz

 There are a few crucial things I'd like to point out about using the Thacker Formula. I've mentioned them before and PDFTD has as well. Although they have been mentioned before I think it's very important they be touched on again.
1) For unknown reasons, it does not work for everybody. A few have seen amazing results and some have seen no results. Most fall anywhere in between. It is very, very doubtful using the formula will rid one completely of his Peyronies Disease. However, it can and has brought relief to a lot who have used it. Remember, even the conventional medical treatments do not work for everybody. The formula is no different.
2) One must follow the instructions to the letter for the best chances of receiving some help from the formula.
3) There may be some mild irratation in the first few days, but if it last longer than that then STOP. You may have to adjust the formula to better suit your skin. If this happens let me or PDFTD know and we can help you adjust the mixture. The important thing to remember is this is not the place to try to be a tough guy and just keep using the formula and say the hell with the burning, I can take it. BAD IDEA!! Always let the irratation go away before starting the application again.
4) If you are in doubt about anything when attempting to use the formula, then STOP and get the answer before going ahead. If you don't you may be sabotoging the treatment or risking a bad skin rash.
5) Again for reasons I'm not sure of, it turns out it is best to take breaks from the formula. What I mean is for some reason the formula will stop working and I found if you give it a rest for 2-4 weeks and restart the treatment; it will start working again. The longer one uses the treatment the longer the breaks should be. My suggestion and what I've found best is for every month of treatment, there should be a 10 day break. For example:
Start by going 1 month of treatment then a 10 day break
Then; go for 2 months of treament and a 20 day break
Then; go for 3 months of treatment
If after this time period you have seen no improvement, you are probably not going to see any using the formula no matter how long you use it.

If you have any questions regarding the formula, please don't hesitate to ask and I'll be happy to answer them if I can. There is so much involved in the Thacker Formula it would take hours and hours to post it all; so I think it would be much easier if I just addressed any question as they come.
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 01:00:09 AM
Posted: Mon Aug 08, 2005 11:39 pm     
 
Guest
 
 
Quote from: Joshua

I wanted you to also chime in on my theory that if this formula works it seems like it would help only the late stage calcified plagues more than soft or new plaque growth. The testimonials of it working (BTC Home Remedy threads) always seemed to indicate it breaks up or splits hard plaques. The research on the ingredients indicates to me it would only have impact on a calcified plaque. Your thoughts?

Anyone like to comment on my theory?
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 01:00:34 AM
Posted: Tue Aug 09, 2005 5:13 am     
 
Rzz

 If the formula is going to work does it work better on plaque that is already calcified?

In my opinion it does not matter. The enzymes in the AVC will break down soft tissue as well as the hard tissue once the plaque has calcified. I have found nothing that would indicate one should only use the formula after the plaque has calcified. However, I would NOT use the formula if being treated with some other agent the is dsigned or used to break apart tissue.
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Old Forum on August 21, 2005, 01:01:08 AM
Posted: Tue Aug 09, 2005 1:04 pm     
 
Joshua

 To: RZZ- But is the ACV not for calcification? Which would only occur in a late hardened stage or am I missing something?

To: PDFTD- If you speak back with Mr Thacker, please invite him to the forum. Thanks
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: Joshua on August 22, 2005, 05:56:58 PM
I am still very interested in an arginine and DMSO mix. I have read about l-arginine being added to diabetic feet rubs/cream to promote blood flow. I would love to see what dmso/l-arginine mixed would do to the penis for blood flow.
Title: Re: DMSO and DMSO based Solutions
Post by: nick on August 24, 2005, 03:07:16 PM
I tried the formula for about 30 days. I followed the procedue to the letter. I even added heat to aid in the penetration. I did feel like a tingling but that was it. I never experienced a taste or anything. My feeling was while i was mixing that the mixture wasn't right. The whole 70 20 thing I had a hard time with. I am more than willing to try again. Could some body help me out in terms that my feeble brain can understand. Like 1 tble spoon DMSO teaspoon  ACV that kind of thing. Also is there really enough enzymes in the ACV that quickly ? Could one add more enzymes ? Any help would be great I would love to try it again. Maybe the formula and the infared light thing as a combo.
Title: Re: DMSO and DMSO based Solutions
Post by: Joshua on August 24, 2005, 07:37:45 PM
Nick:
I suggest you go to BTC and read the entire home remedy threads. I suggest you also PM Barry F and RZZ and ask for advice. I remember something about the brand of dmso being important if not vital. Good Luck and keep us updated , if you try it again. hell, it seems safe and if your in a bad way, go fot it and good luck
Title: Re: DMSO and DMSO based Solutions
Post by: nick on August 24, 2005, 08:44:17 PM
I am going to try it again but I think I f'd up. I got the Nature's way DMSO. 99.9 % pure. After the fact and after all my haste I read on . It is 90% DMSO and 10% distiled water. Is that bad ?
Title: Re: DMSO and DMSO based Solutions
Post by: Joshua on September 02, 2005, 03:24:07 PM
Are you trying the Thacker formula? I think topical use of DMSO has merit but I am reluctant to mix it as instructed in the thacker formula. I know a bodybuilder that uses DMSO after workouts. He swears it reduces pain and inflamation.
The dmso.org website has so much great informtion.
Title: Re: DMSO and DMSO based Solutions
Post by: nick on September 06, 2005, 10:26:41 AM
Yes Joshua I am going to try it again. I stated before but I think I had the mix off. I used a 70% dmso and 30% aloe blend. I did notice though that even with that mix. I noticed a difference in the feeling when using a heating pad. There was like a tingling in the area of the scar. So I would say (personal opinion) when using the formula use a heating pad. Pack and wrap your pecker. Than put on a heating pad. I used the heat and formula for about 30 min. The problem is that I only used it for about 2 weeks before stopping (long story).
Title: Re: DMSO and DMSO based Solutions
Post by: Joshua on September 11, 2005, 08:33:52 PM
Barry:
Do you ever have any further contact with the Thacker family? I hope he will join and answer some questions about the formula.
Title: Re: DMSO and DMSO based Solutions
Post by: nick on September 13, 2005, 10:16:50 AM
Good morning all, hope all is well. I have been fooling around with the Thaker formula over the last couple weeks. Here is what I have come up with. I have a day formula and a night formula. The night formula I stared with the recomended mixture (70-20-10). To the DMSO I first took one neprinol capsule and opened it and mixed with the DMSO. I waited about 30 min to make sie it was completely disovled. After disolved I mixed in the ACV and castor oil. I also added 1/2 part emu oil (half the amount of the castor oil) and a 1/4 part copper pepptides. I use a sterile gauze pad. I take an eye dropper and soak it. I apply it to the area. I then take rolled gauze and wrap it. Once it is in place I soak the rest with an eye dropper. After nice and moist (not drpping) I wrap with cellophane. It seems to trap the heat and cut back on the smell. I use a heating pad for 30 min. Then since I do this in the evening I leave it one for the rest of the night. I must really soak in because the little woman said she smells the ACV on my breath. Keeping My schlong wrapped while sleeping seems to add support too. Now my day formula is pretty much the same mixture. the difference are 3 things. I also open and add 1 capsule of L-arganine and 1 capsule of MSM (I know of the connection of MSM and DMSO). Once mixed I take 1/2 teaspoon (it it perfect for the mix I make) of white petroleum jelly  . I stick it in the microve for 5 sec. just enough to make liquid. While still liquid but not to hot ( to much heat will break down the enzymes in the neprinol and the avc.  I mix the petroleum jelly in with the mix. I put the lid on the container (I'm using a large pill bottle). I shake the crap out it, for about 15 min (good arm workout :-) . I loosen the cap as the heat may pop it off. I then just let the mixture cool and turn into a cream. In the morning after removing the wrap I wash my junk and then slather on this cream. I have been doing this for about 4 days. In the morning the skin is a little raw but the cream helps with that. So I am going to use for about 5 days and then not use for a day. In the 4 days there has been no reduction in curve (no suprise). The one big change is that the hardest portion of the tendon lie plaque and scar feels softer. It also seems to hand a little straighter when limp. With these small results I am very hopeful for atleast a minimal change. Every little stepp forward is better than one back. I am also still taking my enzymes, co-enzymes, multi V and msm.
Title: Re: DMSO and DMSO based Solutions
Post by: Hawk on September 13, 2005, 11:27:25 PM
Nick,

Are you a chemist by trade, or are you just trying to put lab rats out of business? :o

Where in the heck did you come up with this concoction?  Heat resulting from mixing two solutions is pretty solid evidence of a chemical change, meaning you no longer have solution #1 and #2 .  You have a brand new solution #3.  Who can guess what soulution you get tossing in several more components.

Title: Re: DMSO and DMSO based Solutions
Post by: Barry on September 14, 2005, 12:01:36 AM
Joshua,

I have lost contact with Thacker. He stopped replying to my e-mails to be honest. I think he just did not want to be bothered with it all anymore. He was never rude or un-willing to cooperate he was a real nice guy.He just took a hike from it all. Hope that answered your question.

Barry

BTW, If you have any questions about the Thacker formula I will give them a shot if you want me too.
I am one of the final developers of the formula as it is now. Rzz is the other, he put alot of time into it as well.
Title: Re: DMSO and DMSO based Solutions
Post by: nick on September 14, 2005, 05:25:45 PM
No I'm not a chemist :-) Just frustrated like everyone else. I just started reading a bit about compounding. I took that with of the info that we as informed Peyronies Disease sufferers take in.  My thought was damn it if nobody is gonna help us then maybe I can. I do my own test study on myself, make my own formula and so on. I hope this helps . I'll report any all results.
Title: Re: DMSO and DMSO based Solutions
Post by: Joshua on September 14, 2005, 05:56:18 PM
Nick,
Please be careful what you mix with dmso. Remember it is carrying it into your bloodstream. Don't mix anything with dmso you wouldn't or couldn't eat. However, good luck and be careful, PLEASE
Title: Re: DMSO and DMSO based Solutions
Post by: Hawk on September 14, 2005, 06:12:20 PM
Also, it would be my guess that just because an item can be ingested does not mean it can safely be carried straight to the blood stream.  Organisms that are destroyed by the digestive tract or substances changed by the digestive tract may be unhealthy to take straight into the blood and tissue.

CAUTION ! and good luck (to you and the lab rat)  :-\
Title: Re: DMSO and DMSO based Solutions
Post by: Larry H on September 14, 2005, 07:35:23 PM
Please let me add my two cents worth here. I have great, no make that grave concerns about this type of experimentation. All have been admonished by both Barry and Rzz to follow the formula carefully. DMSO is powerful and this is way over the top on the risk meter.

Barry, this needs your input!!

Larry H
Title: Re: DMSO and DMSO based Solutions
Post by: nick on September 14, 2005, 08:00:55 PM
Thank you for your concern. I am and will be careful. There is a certain degree of risk that I am willing to take. I'm not crazy though, there is even a point that I say it's just not worth it. Like the guy once upon a time on the biospecifics forum that was talking about cutting the plaque out with finger nail clippers. That was even to crazy for me.
Title: Re: DMSO and DMSO based Solutions
Post by: Barry on September 15, 2005, 01:24:04 AM
Nick,
Please don't let your frustrations get the best of you. I will not try to stop you from doing what is considered by most bizarre. But I will throw some cautions at ya.This compound that you are taking is contraindicated if you are taking blood thinners,I feel that you should know that. You are taking two transdermal agents just in case you are not aware of that. Dmso and emu oil both have transdermal properties but of a different nature. One is a greater penetrant than the other. This could be a bit shakey with all the things that your taking as well. I strongly suggest that you stop the use of emu oil in tandem with DMSO.Take one or the other,not both.

The smell your wife speaks of would likely be from the DMSO, because DMSO changes its chemical composition when it enters the body and emits an odor from the skin pores and  breath. Also if you are getting a red rash or burn on your unit you need to treat that. First you should stop using the compound until the redness goes away and treat it with pure unscented aloe vera. My friend you only have one pecker and it is already in trouble not by your choice but, this thing you are doing is a delebrate decision to place you unit into a meltdown. I am asking you to exercise some good judgment in what your doing that is all. Don't take my post as an insult or personal attack as that is far from the reason I am speaking with you. Please slow down and consider what your doing and what I have said to you. That is all I ask.  Good Luck!!!!!!!

Barry   
Title: Re: DMSO and DMSO based Solutions
Post by: nick on September 15, 2005, 10:03:37 AM
Thank you Barry I appreciate what you're saying. I would never take anything you say as an attack or anything. I understand what you are saying but at this point I am willing to take the risk. I have myself on a 2 week trial so to speak. After that I plan to evaluate the entire situation. The thing that I put in the mix I am aware of what they do and that why I have used them. I have spent quite a bit of time learning what theses things do and how the body may react. So I feel that the amount I'm using will cause irritation yes. However I feel pretty safe that it would not be fatal or anything of the like. I'm paying pretty close attention to how my body is reacting. I'm checking heart rate, temp, watching for GI issues, staying very hyrdrated. So I am in now way going into this lightly. I don't have the luxury of a lab or little critters to experiment on. When guys started using the thaker formula, soy isoflavones  or any of the other thing we have tried. None of us knew what would happen. So if I can say guys this is working or dudes don't try this, then I feel I have done my part for all of us. I really honestly feel I have to take this risk.
Title: Re: DMSO and DMSO based Solutions
Post by: flexor on September 15, 2005, 11:18:02 AM
While we are all waiting to see if Nick spontaneously combusts, I wonder if Barry or Rzz could comment on the logic behind Thacker’s Formula. I don’t believe that Thacker woke up one morning and thought “Well, last week we tried kerosene, cola and axle grease, and that didn’t work, so this week we will try  DMSO, ACV and Castor oil, and if that doesn’t work, next week we will try something else.” I suspect that Thacker may have had a good reason for using these items, and that any experimenting would be in the percentages.

1. DMSO. A skin penetrant. So that makes sense, but is that all it does ? If DMSO is only a carrier, then only the ACV and the CO can be the active ingredients. Or does DMSO itself have some effect on the plaque ?

2. Apple Cider Vinegar. Vinegar is an old wives remedy for clearing scars. Any other reason for its use?  Why Apple Cider vinegar ? Did Thacker live in an apple-rich community, and this was the easiest to hand, or is there something special about ACV, which means it is the only one to use?

3 Castor Oil. This is the odd one. Looking through the literature of things that have been tried for Peyronies Disease, Castor Oil does not appear. Is it of a molecular weight that can be carried through the skin by the DMSO? What role would it play if it gets to the plaque? Does it soften it ? Or is it just a topical emollient, like zinc & castor oil ointment, to sooth any surface skin irritation caused by the DMSO.
Title: Re: DMSO and DMSO based Solutions
Post by: Glenn on September 15, 2005, 11:41:59 AM
Flexor,

In the E-Book "The Naturapathic Approaches to Peyronies Disease"  by W. Bodri there is disussion of the Thackers Formula's ingredients.  I would try to post some of it but it is 7 pages long.

Castor Oil among some naturopathic  groups is heralded as having various  healing potential.  It alledgedly works to soften and eliminate cysts.  If you want, I will be glad to try to email you some of the discussion of ingredients. Each one of them has a basis in naturopathic reputation for being included in the formula.

Glenn
Title: Re: DMSO and DMSO based Solutions
Post by: bob on September 15, 2005, 12:09:36 PM
Castor oil seems to be a favored remedy among naturopaths. My wife and I brought our daughter to an N.D. when she was 2 1/2 for a facial rash. She diagnosed food allergies using kinesthesiology - kind of a wierd regimen if you ask me, but we removed items from her diet and it worked. She also gave us a bottle of castor oil to rub on her belly. This was supposed to have something to do with her systemic issues regarding both the allergies and her impulsiveness. (She's 7 and still hard to control.) She cautioned us just to use the kind she gave us. There's a message on the bottle: "Recommended in the Edgar Cayce readings." He sounded vaguely familiar, so I looked him up. He was a weathy spiritualist.
Title: Re: DMSO and DMSO based Solutions
Post by: Glenn on September 15, 2005, 12:29:25 PM

DMSO is used in other countries by itself as a remedy for various things.  It has never made it past the  FDA for use in US, but it is used in European, Asian, and Middle Eastern countries.  One of the more commonly known uses is wrapping sprained ankles  with it.   It reportedly takes the swelling away within an hour or two. 
Title: Re: DMSO and DMSO based Solutions
Post by: Barry on September 15, 2005, 02:28:26 PM
Flexor,

The Thacker formula came to the Peyronies Disease community a few years ago from a post on the now useless forum www.biospecifics.com  . It is posted under “powerful home remedy” and “powerful home remedy thread 2”. There are over 1000 posts, which made it the most talked about topic, ever, on that forum.

The formula, an alternative treatment, was created by a Doctor, his name was Thacker. I maintained conversation with his grandson for a few months off and on and we discussed his grandfathers’ treatment. Thacker himself had Peyronies Disease, all the males in his immediate family had it, as did Doctor Thacker and many of his patients whom he treated with this formula.

I will post to the PDC web site by your request the formula and how to use it. It harmed no one and has efficacy proven over time as used by many who reported results. Many had no remarkable result. The formula has been the study of a compound pharmacy in the past. This pharmacy had no comments inferring danger.

That Flexor is the extent to which I will go as far as your multi question post is concerned. I don’t suspect that if you have an RX filled you pick the pharmacists brain to the extent that you are attempting to pick rzz or mine. With that said you have over 1000 posts to read which will satisfy many of your questions in detail, all that is needed is the time and effort to read all the posts.

Regards,
Barry   

   
Title: Re: DMSO and DMSO based Solutions
Post by: Barry on September 15, 2005, 02:50:33 PM
Glenn,
Actually the use of DMSO is approved by the FDA in two medical treatments.The first is in the event of head injuries that involve swelling of the brain. The other is a specific condition of the bladder that escapes me now.

You are so right on in your post about the use of DMSO in Europe and other areas of the world. DMSO is the leading treatment in Russia for arthritis.

Barry

PS: Welcome to the forum and thanks for your contribution
Title: Thacker Formula- A 1000 Post Archive from the old BTC Forum & related new posts
Post by: Joshua on September 19, 2005, 07:57:12 AM
Peyronie's Disease Patient Discussion Forum 
 
Topic: "powerful home remedy"
 

 
Date:   4/29/2004 8:49:47 AM
Name:   Vick 
Bump for the new guys.

 
Date:   4/10/2004 5:01:57 PM
Subject:   Thread 2
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Dr.Knutson,
You have a much better chance of you posts being read if you post on the Powerful Home Remedy 2 thread.This thread is used as an archive.I am the poster who reffered you to this thread on the Yahoo forum if I failed to mention thread 2 then it is my error and I apologize.

Barry 

 
Date:   4/10/2004 3:52:19 PM
Subject:   THE BREAKTHROUGH AT HARBOR UCLA....
Name:   steve 
Email:   sbemax@earthlink.net 
this a breakthrough.....l-arginine + viagra.....the article is here....dr. rajfer is considered to be the foremost authority on peyronie's.....

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=14996430

animal studies follow as soon as harbor ucla raises the money....i've heard that the treatment was innocuous in rats, meaning that "good fibrin" needed for clotting, was not at risk......NO ONE IS CURRENTLY INVOLVED IN HUMAN TRIALS...

 
Date:   4/5/2004 5:39:25 PM
Subject:   Dr Knutson
Name:   kingfish 
Dr Knutson ...To many times Ive noticed angry responses to someone elses opinion. Im not going to lash out at you. But realize that not everyone that has tried this "home remedy" is a fool that is trying to rush into a magical cure. Like Many men on here , Ive done my homework to find out what might help and what is a waste of time and money.

Do you have peyronie's doc??

Most of us know that peyronie's can resolve itself in a year , but some of us are well beyond that point. But thanks for that incredibly helpful info.

Doc Knutson quotes quotes "this formula has not stood the test of double blind studies and many reteste and scientific publication. The basis of science."

YOU CAN PUT THE BOOK DOWN NOW DOC***

You also say the suggest that the formula is flawed .. Care to explain flawed..
You also seem to think that the thought of absorbing apple cider is a joke. Absorbing shower water , Is that some kinda of smartass comment to make your a$$ feel smart?
Have you done any research about dmso and its penetrating
abilities.

Ok I think thats about it, no big deal. Im just ready for a "doctor" to come up with ways to help and stop thinking that everything has to be on a scientific platter!

Dr Knutson if you respond do so on powerful home remedy 2..

 
Date:   4/5/2004 5:06:16 PM
Subject:   Dr nutson
Name:   kingfish 
 

 
Date:   4/5/2004 4:33:53 PM
Subject:   Thacker~sq~s Formula Comment.
Name:   Dr Knutson 
Email:   drknutson2003@yahoo.com 
A patient referred me to this website and referred me to this board regarding the 'Thacker' Formula.

There does seem to be a large response of individuals under the impression that it is a 'miracle' cure. Keep in mind, it is stated that this was created by some guy's grandfather who 'was' a doctor. Well, I would guess, unless he's still in practice and a urologist, that he's out of the loop and has been for a while.

The problem with this 'home remedy' is that it gives a false perception. Please realize, most, if not all, urologists will not perform corrective surgery unless the problem has been stable for at least a year. This is important because in many cases, Peyronie's usually resolves itself within a year, and sometimes after this timeframe.

This is important. Persons using the Thacker formula could be experiencing resolution to this disease as a normal process of healing, and mistakenly attribute it to the Thacker formula.

As listed in this and other forums, Peyronies Disease is under research, and there are new thought paradigms forming as to the similarities and differences in types of Peyronies Disease.

Point being, this formula could, and most likely usually is, attributed for the healing your body does on its own. Also, this formula has not stood the test of double blind studies and many reteste, and scientific publication. The basis of science.

I should guess I am not and will not be the first to review this formula. The basic physiology and biochemistry of it is flawed. The suggestion that we absorb apple cider. I don't absorb apple cider any more than I absorb the water from my shower.

Please be wise to what you choose and learn about your options before choosing such home remedies.

Jim Knutson

 
Date:   4/3/2004 12:46:53 AM
Subject:   interferon works/tulane publishes article
Name:   steve 
Email:   sbemax@earthlink.net 
interferon study dated feb 2004, proves that interferon works.......here's the link........

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=PubMed&list_uids=14746421&dopt=Abstract
 

 
Date:   3/29/2004 9:39:41 AM
Subject:   Fellow Peyronies Disease Sufferrers
Name:   2-Cents 
Please read these posts from "Thackers Original" to the present. This should answer most of your questions. Then go to "powerful home remedy 2" and add your questions and results. I think this could be of great benefit to you and all who monitor this post.

 
Date:   3/28/2004 8:14:25 PM
Name:   Robert 
This formula has been a blessing! It has returned my erections and releived so much "tension" or tightness, pain I was feeling in my penis. The curve has reduced and I think I am moving in the right direction now and starting to recover. Thanks to all that have brought this formula to light!

 
Date:   3/19/2004 5:43:53 PM
Subject:   To RZZ
Name:   Ted 
Correct, I was confused. I found the 2nd thread good idea!
See ya on thread 2
Ted

 
Date:   3/17/2004 10:52:52 PM
Subject:   stopped
Name:   Rzz 
Ted,
What makes you think everybody has stopped using the formula? I know of only a few, but I know of more who have started using it. You may be confused because of the decrease in post you see on this thread. That is because this thread had become too long and everybody has moved over to the thread titled:
"Powerfull Home Remedy ... Thread 2"

 
Date:   3/17/2004 8:55:13 PM
Name:   Ted 
Why has eveyone stopped using the formula. I started about two weeks ago and love the results! It's the first positive results I have had in two years!
TED

 
Date:   3/11/2004 2:51:44 AM
Subject:   final post on this thread
Name:   PDFTD 
Email:   pdftd@yahoo.com 
I have a message to BB and KK you can find them on thread 2

Bye and good Luck

 
Date:   3/11/2004 1:27:29 AM
Name:   Nemo 
Agreed - let's all go to Thread 2.

This one has served it's purpose and causes too much drag on various systems ... we can always go back to check info if needed.

Nemo

 
Date:   3/10/2004 10:21:22 PM
Subject:   PAZ
Name:   Larry 
Paz my friend, I'm not trying to cut you short, but I request that all replys be made on thread "2" as set up by Barry. This first thread has just gotten a bit out of hand.

Thanks,

Larry

 
Date:   3/10/2004 8:18:15 PM
Subject:   1 question if I might........
Name:   PAZ 
I have been following this site for some time, I have been diagnosed with Peyronies Disease, however it seems to be a little different than most. It curves to the right, and there is no nodes, just a very tight ligament? (I guess) It still works but seems so odd. I have long felt that DMSO would play a role in this as it is used as a linament for horses and can be purchased at most feed stores. My question is with the lack of nodes, and just the tight shortened ligament, would you think the vinegar and castor oil would still be needed, what agent are the horse trainers using with DMSO to affect the ligament or is it the DMSO itself that has the softening affect that would allow anyscartissue or hardened ligament to loosen up? Is there any damage that can be done? Can I make my bend worse by adverse affects from DMSO? I have read through these posts and the consensus seems to be that DMSO if applied correctly will not cause harm, but of course I am not a dr. or pharmacist, and that is what make sone wary.

Thank you if you care to weigh in.

 
Date:   3/10/2004 7:30:57 PM
Subject:   general
Name:   PDFTD 
Email:   pdftd@yahoo.com 
To kingfish,
Thanks,I appreciate the info.

BTY,
Barry


On another note Larry brings to point that this thread is so large it is difficult to find information.I would like to suggest that we archive this thread and start Powerful Home Remedy thread 2.The archived portion can always be bumped up.600+ posts is too much to keep up with on one thread.

Best To All,
Barry

 
Date:   3/10/2004 7:10:57 PM
Subject:   correction to KK
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Hi kk,
Sorry for the error the last sentence should have read.....

If you start with 99.97 and it has not been cut by the maker then you have a 99.97 potency DMSO.


Again sorry for the confusion,I have 11 e-mails to respond to and other posts to type so my head was up my keester.

Best To Ya,
Barry

 
Date:   3/10/2004 6:49:13 PM
Subject:   To KK
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Hi KK,
I told you that jacobs would be my first choice.Please allow me to restate myself.Jacobs labs sells a 99.97 pure DMSO but,it is cut with 30% distilled h2o.
This means that the DMSO has lost 30% of it's potency.
after you add 20%ACU and 10%castor oil the potency of the DMSO is reduced to 40%. please keep this in mind.If you want me to dig up some companies that sell 99.97 or better
and sell internationally let me know and I will post some for you.

If you start with 99.97 and it has not been cut by the maker then you have a 70% potency DMSO.

BTY,
Barry
 

 
Date:   3/10/2004 6:14:03 PM
Subject:   DMSO Smell
Name:   Larry 
Is anyone using a pure DMSO with the formula that doesn't cause bad breath and body odor along with the oily taste in your mouth that some report.

It seems to me that someone said a particular brand had very little odor, but this thread has gotten so damn long that I can't find it.

Larry

 
Date:   3/10/2004 4:31:06 PM
Name:   kingfish 
Barry, i respect the fact that you arent suggesting sski because of lack of knowledge about this mineral(you take pride in not misinforming anyone) and I want everyone to know that I am not suggesting this either because I only have limited knowledge myself on this. I guess you can say Im taking my own chance because im somewhat confident from what ive learned. But im no chemist, just a guy trying to beat the odds.
Answer to your question Barry: I ordered 1oz (600 drops)each drop provides approx. 50mg of potassium iodide(sski) and water soluble apocaroteroids extracted from crocus sativa. One bottle is 19.00
If anyone is curious to learn more about this I would go to google and type "tahoma clinic" then in the search for info square on the home page type potassium iodide. Dr Jonathen V. Wright has a lot of interesting knowledge it seems on the use of dmso,sski,and it was enough to get my attention...I might try to call Dr. Wright sometime to see what he has to say.. PEACE OUT

 
Date:   3/10/2004 3:37:47 PM
Subject:   THACKER FORMULA AND DSMO
Name:   BB 
Email:   emsmedic82@yahoo.com 
I am looking for any and all infomation (web links, articles, names, chemical, biochemical, and molecular) on what the Thacker Formula is and what DSMO is.

Please reply or email to the above email! Everyone's help is appreciated!

BB

 
Date:   3/10/2004 2:12:07 PM
Subject:   General
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Hi Guys,

To Steven, I hope your V/I is doing well for you .In answer to your question, In my
Opinion because V/I involves injections I don’t think that V/I and Thacker is a good idea
Only because Thacker is topical and V/I is an injection leaving an open wound. But by in large this is a judgment call for you. I personally would not do it.

To KK,
Have you tried a google search? Jacobs labs would be my first choice.

To Rzz,
Welcome back, take some more time to grieve if you need to we will still be here
When you get your head clear.

To Charles,
The Thacker Formula is a non-invasive therapy and as you probably know is a very
Popular and up and coming treatment. It is always recommended that when a man
Finds out that he has Peyronies Disease that he try to arrest it in its early stages. Too many Doctors
Are saying take some vit-e and come back in a year. I think not!!!!! These are the docs that should be avoided and sent back to school and forced to admit that they don’t know squat about Peyronies Disease. There is a window of 6-18 months that Peyronies Disease could naturally just go away but because this is believed to be a rare occurrence it’s best to treat it in the early stage.

To kingfish,
I recommended staying away from sski because rzz is the sski guru on this forum
And he is in the end stages of implementing sski into the thacker formula. I have done
Some research on sski but where this drug is concerned I defer my opinion to rzz. So many people talk about should I use it or not my recommendation was because I in good conscience
Could not say what strength and quantity to use. I have over 4 years of research and experience with Peyronies Disease and treatments but sski is not my forte.BTW.what strength are you using?

Best To All,
Barry
 

 
Date:   3/10/2004 1:59:32 PM
Subject:   To Rzz
Name:   KK 
Email:   kkrilik77@hotmail.com 
Once again, my condolences...i know exactly what you are going through!! Keep up the good spirit. My prayers for you and his family!!

Rzz, I have a question (s). I wat to buy the DMSO from Jacobs Lab. They will ship it to the UK where I live. Should I buy the one that says

"70% DMSO is used when a stronger DMSO solution is required. 70% DMSO must be applied below the shoulders where the
skin is not as senitive. Contains 70% DMSO w/v (700mg/mL) in deionized water.
How Supplied: Topical Solution, 8 oz. (240mL)
Storage: Room Temperature, Shelf Life: 5 Years"?

If I udesrtood well, this one would not have to me cut with water, since it has already been cut right? Ok,ok, im not a chemist...only one year at school...

What do you think of putting the formula, and taking potaba as well? Ok, you have 4m onths of researh ahead of me...Im just looking into the topic.

Ther was something that brought my attention. SOmeone asked before, Is this formula also good in the early stages? I mean i have a lump, and its hard, but is there a difference when is calcified?

Ok, I know they are repetitive, but want to make sure of what I am doing. Please let me know!!

Ok guys, will keep on posting when I get my products!!

PS. Im 25, is it normal to have pain aroung the prostate, anus, and testicles? Old Man, Barry, can you help me out on this? I am seeing new veins as well commin out, is that varicose? Ok let me know!!! Thanks in advance!!

 

 
Date:   3/10/2004 1:46:47 PM
Subject:   JUST started....
Name:   scared 
Hi barry and eveyrone else

I JUSt adminstered my first sterile gauze strip of Thackers 40 minutes ago...right now I feel a tingly burning sensation IN my penis...where I placed the gauze...not on my skin...but inside

it not strong but definitely can feel it

is this a normal reaction?

Gosh I hope I am not doing more damage...I am very nervous

please walk me throgh this guys!

 
Date:   3/10/2004 12:31:35 PM
Subject:   ~.~,~.~
Name:   kingfish 
Barry , Good post on the basics of thackers formula.That is the proper method and the simplest that is accurate. Quick note though.. Dont confuse sski (potassium IODIDE) with IODINE. You should NOT apply iodine thats for sure and i wouldnt add iodide to the thackers formula. But i have been adding a few drops of sski(iodide) while massaging the plaque with jacobs dmso topical gel ,been doing this a couple of weeks now. I have had no ill effects , in fact my penis seems to be getting healthier by the week.Im still a fan of thackers formula but i have been slacking on doing it lately if only done the wrap 2 times in the last 2 weeks. I am still taking oral excelsa and bromelain,vitamin E ,gota kula,and a couple of teaspoons of apple cider vinegar/organic honey everyday.Once again i dont seem the harm in adding any of these to my daily routine because they seem to be beneficial anyway(not only to peyronies)but for general health.I try to keep my outlook simple im basically trying to work out the left side of my penis (the side with the plaque)massaging the plaque with my thumb gently in circular motion. Im doing this daily and im getting better its just that simple. I might not have it as bad as alot of guys on here , because ive never had a problem with getting erection although it was kinda painful for lil while , i just ignored it because im hard headed. Im 25 now and i was having rough sex and just handle my dick roughly when i was around 15,16 ( not to mention this girl was on top one time and came down full force and i slipped out of her and damn her pelvis felt like a tree trunk) and the curve gradually developed and i didnt even pay attention to it , I continued to have all the sex i wanted and never held back. This probably kept adding to the problem.I finally came to my senses a couple of years ago and when i seemed to have trouble aiming my pi$$ because my pecker had been through a damn war. But I have since then taken it easy on my penis and started trying to take care of it(so it would be useable when i am older) And with much persistance and TLC ive gotten my unit almost normal again.But this is just a little bit of my story , and im still waiting to see what Rzz has learned about sski and he has been dealing with issues way more important than this so i understand that. Keep your hopes up fellas and be always be careful when those girls get on top of you and start riding you like a damn bull. jk. Im outta here.

 
Date:   3/10/2004 12:09:19 PM
Subject:   rzz...& earlypeyronies
Name:   Charles 
first of all rzz, sorry for your loss and thank you for your selfless giving of important information to all of us

secondly, I have a question for the participants in general...should the thacker formula be used for Early stage peyronie's disease? I have a slight bent, no pain, but I am feeling soft plaque which is starting to get harder and bigger...but the plaque has yet to totally calcify...

what do you think?

 
Date:   3/10/2004 11:20:44 AM
Subject:   Rzz
Name:   Larry 
Rzz,

So very sorry to hear of your loss. The sudden death of someone so young, either family member or friend is hard to deal with, and understand.

My Best,

Larry

 
Date:   3/10/2004 9:28:06 AM
Subject:   Back in the mix
Name:   Rzz 
Friends,
Just got back from my buddy's Funeral. Emotionally, next to my father passing away, burying my good friend was the hardest thing I've ever dealt With. Worse than Peyronies Disease? YES!!

I'll be back in the mix real soon, just give me a few days back home to get resettled in. Talk to you soon. 

 
Date:   3/10/2004 8:41:07 AM
Subject:   DMSO & Potaba?
Name:   KK 
Email:   kkrilik77@hotmail.com 
I am taking Potaba as well...anyone knows how Potaba can affect the formula? Anyone taking the same?

 
Date:   3/10/2004 8:39:51 AM
Subject:   DMSO in UK??
Name:   KK 
Email:   kkrilik77@hotmail.com 
Anyone knows where I can get DMSO in the UK? A good quality one? Barry, Rzz, or others..have you got any clue?

 
Date:   3/9/2004 11:42:21 PM
Subject:   Great Recap
Name:   steven 
Barry,

Excellent recap!, I was reading through the posts trying to put it all together and it was confusing the hell out of me, my brain was getting Peyronies Disease. Great stuff!!, I wonder if using this while undergoing Verapamil Injections would cause a problem?. Anyone know?, probably not a good idea. I know I sound in a hurry, that's my nature, can't help it. Also is this a lifetime treatment or do you think once it causes improvement its a done thing.

Thanks again Barry....
Steven

 
Date:   3/9/2004 11:30:39 PM
Subject:   first (MINI) step
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Hi again,
Good 4 u.I wish you luck and a clear mind.Keep Me/forum posted 4 sure.I'M very happy that you took the first step.

MY VERY BEST TO YA ,
Barry

 
Date:   3/9/2004 9:59:42 PM
Subject:   first (mini) step...
Name:   scared 
BArry, thank you very much for your post

before I chance to read your words, I mustered up the courage and started by rolling on the DMSO with aloe (it took me about 15 minutes standing in front of the mirror all nervous lol)...I wanted to try the weak stuff to see if it burned or anything...I rolled in the area and put a sterile pad over both sides of my penis and I have been pressing the pad with my hand from to time and against my penis...

I am getting the Apple cider vin and castor oil ASAP...as in tomorrow...and I'm going for the Formula as you described...with the sterile gauze and syringe for appropriate measurment...

tonight I am just going to continue to apply the dmso w/aloe vera

what I noticed immediately was the LACK of viscosity of this stuff...its basically like water...I expected something thicker

also very little smell to this roll on...and thus far, no burning at all...

ok i will keep everyone posted...best of luck to you barry and everyone else!

 
Date:   3/9/2004 9:04:52 PM
Subject:   Message to Scared
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Hi,
First please let me say there is no reason to be scared.you are only human and subject to human emotions.To be scared is an emotion but it's not like you are taking your first free fall at 20,000 feet.Calm down my friend,take some deep breaths and realize that you are taking a positive action to combat your Peyronies Disease.This is a good thing.

The DMSO70% aloe vera 30%roll on is great for muscle aches and strains.But caution should be taken not to use it above the sholders.It is not an effical therapy for Peyronies Disease.Aloe vera does not have the healing powers needed to get the job done.

To test the true potency ofthe DMSO put it in the fridge for a few hours and see if it cristilizes or as others say gets hard.The litmus test for true DMSO is at 67 degrees F.
If it does not do this then buy another brand,this DMSO you have will not work as well if it does not pass this test.

You will need to buy some Apple Cider Vinegar and castor
oil to complete the formula.Don't premix the formula!!!!!
Mix it as you use it and throw the rest away.

The DMSO is 99.9% pure get a small vile or dropper that has measurements of ten put 70% of the DMSO into a sterile beaker or even a shot glass would do,take 20% vinegar and put that into the DMSO,then take 10% castor oil and blend that with the DMSO and Vinegar stir it to blend and put the formula on a steril cloth,large gause pads are the best alternative.DO NOT use a cloth that has been colored or the coloring will be sent into the penile membrane by the DMSO.Wrap this gause pad around your penis and place a rubberband around the penis as well on to the gause pad to keep it in place.DMSO is the delivery agent and in part one of the active agents,the Apple Cider Vinegar is the primary active agent,and the castor oil is the base that keeps all the components together.Keep this wrap on for 1 1/2- 2 hours.Remove it and throw it away.it is suggested that this procedure be done daily at least once.

DO NOT add any other ingrediants to the formula or modify it in any way especially with sski whick is also called potassium iodine.Some people report modest results in as little as threee days ,others take weeks or a month or two.Don't give up until at least 4 months,minimum.

If I left anything to doubt or question you can reach me on the forum or at my e-mail address.Go for it my friend you have nothing to loose and everything to gain.Good Luck.

BTY,
Barry
 

 
Date:   3/9/2004 7:13:52 PM
Subject:   Message To Steven
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Hi Steven,
No I am not using the Thacker formula.I am using the S/I formula for about 2 years.I would usee the thacker formula in a half a heart beat if the S/I formula was not doing a satisfactory Job.I would recommend the Thacker formula to anyone seeking a good non invasive treatment that is fast in proving itself.Hope I was of help to Ya.

Best To Ya,
Barry

 
Date:   3/9/2004 6:12:21 PM
Subject:   scared!
Name:   Scared 
Okay guys ...help me through this...I bought to bottles...one says 99.9% pure DMSO liquid...the other is DMSO 70% aloe vera 30% roll on

whew...I finally got the guts to buy it after reading most of the stuff on here


The stuff I got is from Ghent, KY...anyone else get stuff from there???

is says to be used as a solvent only...so I am nervous guys! should I go ahead and try it? if so, which one...and how many times...should I wrap it or what....thanks
 

 
Date:   3/8/2004 1:14:07 AM
Subject:   the formula
Name:   steven 
PDFTD, Have you tried Thacker's formula? I am thinking of giving it a try if the VI doesn't work, just curious if you tried it and if any results.
Steven

 
Date:   3/7/2004 2:57:03 PM
Subject:   Responce/update
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Vick,
I am glad that you are having results with The Thacker Formula.You are among a growing number of people who are.
From what I have seem on this forum keep using it and the tough guy nodule may succum to the treatment as well.
Good Luck.

Best to Ya,
Barry

Adam,
I do agree that DMSO is OK and safe to use stand alone.It has been used by athletes,weight lifters,body builders and more for quite some time in various potencies as an anti-inflammatory.It's penetrating abilities are remarkable.

Verapamil Injections is an accepted treatment for Peyronies Disease.But the efficacy claims are not as high as stated.The same is true for Topical Verapamil.

To the best of my knowledge DMSO and Verapamil have not been mixed on this forum or by any compound pharmacy or Chemist I don't know the molecular weight of verapamil so I can't say with any degree of certainty that DMSO will deliver it to the afflicted area.The compouding of DMSO/Verapamil would need to be studied before used so there can be a risk of danger.In my opinion the Thacker formula was a fluke that came to us and was easy to check out the components of the formula before trying it.

Your statement that the two would be a effical treatment may very well be true,but I don't have the confidence in verapamil that I did.

In MY OWN opinion I am not fond of invasive treatments as of yet.V/I,VED for examlpe are very invasive treatments and the penis takes a working over with these treatments.I would not use them but that is again ,my opinion.

I am waiting for collaganase to come into the market to see how true it really is and if it lives up to it's alleged reputation.The problem for me however is that it involves injections.We have to wait and see.

Your statement about Grandpa Thacker holds true and I can't disagree with that but I,by my nature and Profession question all and leave nothing to chance.Verapamil is not proving to me to be as claimed.And the makers of T/V Pdlabs will not provide numbers to attest to their claims.Blind faith?????I think not.V/I involves too many injections for me to allow,too much trauma.But again this is my opinion.
With the advent of micro-trauma I am very dubious of treatments that involve an invasive style of treatment.The jury is still out(so to speak)on collaganese.

Best To Ya,
Barry 

 
Date:   3/7/2004 2:28:16 PM
Subject:   an explanation...
Name:   leeroy 
Email:   setonedge1@excite.com 
"I have a question for you......You stated that it sure get's down there.......could you be more articulate with that statement please?"

What I meant is that DMSO definitely gets into your penis - for several hours after a treatment my penis is THICK and just generally bigger - it's as though it were waterlogged. Also, my erection are significantly thicker for at least 12 hours after a treatment. Seems to me SOMETHING is happening, that's for sure.

 

 
Date:   3/7/2004 10:03:57 AM
Subject:   Barry
Name:   Vick 
Thanks Barry Great post with some new info I appreciate it. I have had luck with this treatment. It seems to it a sticking point on a piece of a nodule that it can't seem to get rid of. However, it worked like magic on softer plaque

 
Date:   3/7/2004 6:02:28 AM
Subject:   DMSO and Verapamil etc.
Name:   Adam 
Barry,

Thank you for your post. Too bad about your hard disk, I hope you will recap your data.

A couple of comments/questions:

Since we already have accepted DMSO as a part of a treatment for Peyronies Disease, it seems that the stuff by itself is safe enough, do you agree?

Verapamil has been used by injection and Ionphoreses and is also an accepted treatment.

Unless the mixing of these materials can alter them in any way (and I had asked Rzz to inquire the Jacob's about this very issue - no answer yet), why would you think this idea can be dangerous?

I would think that if they can be mixed without any changes to the molecular structure of either, this could very well be a potent treatment. Perhaps you check your sources for an answer to this question. If Collagenaise becomes available again, that may be an even more interesting solution.

Remember, at the time Grandpa Thacker invented the "powerful home remedy", he did not know about Verapamil and/or Collagenaise ;-)

 
Date:   3/7/2004 3:37:51 AM
Subject:   Leeroy........DMSO
Name:   PDFTD 
Email:   pdftd@yahoo.com 
leeroy,
I am very glad to hear that you feel optimistic about the Thacker formula and it's potential.I don't know what brand DMSO you are using,but some brands claim that they have quelled the garlic smell to a minimum.

I have a question for you......You stated that it sure get's down there.......could you be more articulate with that statement please?

Your question about verapamil and Natto deliverd into the penis via DMSO as the delivery agent is of great concern to me.Others on this forum have asked similar questions.If the truth be known DMSO will deliver just about anything that it is mixed with or comes in contact with into the body and will ultimately end up in your tissue and blood stream.
Understand this if you will .......DMSO is not a solvent to be experemented with lightly.If handled wrong or used incorrectly it CAN hurt you.I have studied DMSO for over a
year and realized it's potential as a viable medicinal component but on the other hand it has potential as a very harmful component as well.Not because of it's label as a solvent(water is a solvent)but misuse and lack of understanding of what this stuff can do.I wrote a post about 14-16 months ago that DMSO will find it's place in the treatment of Peyronies Disease.Then came the Thacker formula and it is tried and is showing it's potential as an effical treatment for Peyronies Disease.rzz is likely trying to figure the molecular weight of sski and be sure that sski can be added to the thacker formula and not be harmful to the tissue of the penis and will attack the plaque with positive results.His efforts are certainly to be commended.And if it can be done then he will find a way.

I will warn off anyone who attempts to use DMSO as a delivery agent to Natto, Vit-e or anything they don't know about.Until my harddrive pooped out on me I had an 11 meg
folder on DMSO/MSM alone now I am trying to regain the info I lost.I am not claiming that I am a DMSO guru but 11 megs was a lot of info and took me a long time to obtain and learn.

All i am really trying to say is Don't mess with DMSO unless you learn about it well or consult someone who knows about it.Compound Pharmacists and chemists are the best off line source.Do research on the web there is a ton of info,you just have to look for it.

Dmso is approved by the FDA for two treatments only, one is a head injury which involves swelling of the brain and the other is a bladder infection.SO your family doc will not write a script for DMSO/Verapamil because he does not how to blend the two.Verapamil comes in many strenghts and he would not know whch strenght to use.He would not know as well the proper potency of DMSO to use.On top of that this type of medicament would have to be made at a compound pharmacy,and a script would be required to get it.

Please don't play mix and match with DMSO,you may regret it for the rest of your life.There is so much more that can be said but I believe I made my point.If anyone has any questions I would be glad to address them on or off the forum.

Best To All,
Barry

 

 
Date:   3/7/2004 12:24:03 AM
Subject:   Has anyone ever considered...
Name:   leeroy 
Email:   setonedge1@excite.com 
Well, I've been using Thacker's formula for a couple of weeks now, and a few things are for sure.
1. i stink - what was the secret to not smelling so awful?
2. it definitely gets deep down in there.

has anyone, i wonder, ever considered using DSMO as a delivery tool for topical verapamil?
or how about adding Natto to the Thacker formula? D'ya think that might help?

Any thoughts would be great...
leeroy

 
Date:   3/6/2004 1:34:15 PM
Subject:   KK
Name:   colt   
What you are experiencing is normal except for the rash.
Your posting reminds me that we in the USA should not want socialized medicine. At least we can usually take our insurance to a specialist in another state or area. I am in project now but will try to address your posting in more detail. Good luck.
PS How old are you? If you are 40 or older, you may be having prostate problems. We, on this message posting board, should never diagnose and I am not trying to, but have the prostate checked out. I am basing this on my experience. Consider a psa test. Prostate Specific Antigen
test. Depending on your age, a reading of 2 to 4 or higher should be followed up by a free psa test.

 
Date:   3/5/2004 10:13:30 AM
Subject:   Symptoms...Consequences
Name:   KK 
Email:   kkrilik77@hotmail.com 
I've been having Peyronies Disease for 8 months...and I have tried different things, but just seem to get worse everyday...luckily I got into this forum yeaterday, and I must say it feels like an Oasis in the middle of the dessert!! I have read most of the string, and I have to thank everyone, specially Rzz, for all the effort and the support given to everyone. I will be writting more often, since I guess I have finally found a place where people can understand what I am going through.

Anyway, I wanted to ask something about the consequences of having Peyronies Disease. I know that is different for everyone, but I wnat to know, if after you got the disease, by accdient, or natural reasons, did your penis started to get hard withouth being erected. Meaning this, all the Coporea Cavernosa is like experiening cramps!! Well, it happens to me, not only have I got a problem with the plaque, and the pain, but also when is not erected, it gets hard...I ve been trying to set up a pattern, and trying to figure out why does all of it gets hard without being erected, and I have noticed that when I get stressed, nervous, excited, or when I am wearing jeans, it happens to do so. But when I am laying down, sleeping, or relax is back to normal...except for the plaque, which is always hard. I have read some things, and does anyone know if this has to do with a hormone/relaxant in the penile tissue called Prostaglandin E1? Is the lack of this relaxant that produces the cramps?

This has developed into something more serious..I am getting pain in the prostate area, and the anus. After I urinate, urine is not fully dischargedm and i have to 'milk the penis' for a while. Recently my penis is redish, and itchy where the plaque is.

So, I want to know if anyone else had this while the disease was developing... I live in the UK. and finding a doc here is just horrible... unless you are private patient... But i have been to my GP and he said that the red and ithchy thing it might be realted to a fungi...so i am applying a cream...

That leads me to the second question, and is if anyone knows any organizations, or groups, or counselling, specially for this where I can go in London!! And this leads me to the third question... I am going through a deep depression, I feel it...It is ruining my personal and professional life... How have you coped with this disease??? I need to balance my emotional life, and cant seem to get an answer!!!

Thanks for everyone here, and bless you all!! As of today, I will be joining the discussion much more often, and will put in practice what this formula can do...of course the idea is to share my knowledge with you guys as well...docs seem not to care that much!!!

If you can answer me with suggestions, i would appreciate it a lot!!!

PS. RZZ my deep condolences...My best friend killed himself in an accident two years ago! I fully uderstand your feelings!

 
Date:   3/4/2004 11:21:14 PM
Subject:   results to date
Name:   Bobrak Karmal 
using formula since early December, 03. Plaque is not reduced. Erections were better though. Have had Peyronies Disease for about 3.5 years. The only thing that has really helped is plaque squashing/squeezing. I can narrow my plaque from 1/2 inch wide to 1/4 inch, but the next day it goes back to the same shape. The manipulation does seem to rubberize the hard area. It appears to be slowly shrinking with time. Another four years and it will be gone. Its a long process.

 
Date:   3/4/2004 4:52:52 AM
Subject:   Rzz
Name:   testme 
My heart go's out to you. I am a Fire Fighter for Devon Fire and Rescue in the UK and deal with RTA's on a monthly basis, more and more are motor cycles.

testme 

 
Date:   3/3/2004 4:00:51 PM
Subject:   Nattokinaise
Name:   alex 
I was wondering, what do you guys think about Nattokinaise...an anti fibrin herb I believe...I am taking Vitamin E only but I wish to add some thing that will address my existing calcification...thanks

 
Date:   3/3/2004 10:50:52 AM
Subject:   Steven - progress
Name:   Dick 
I've been doing Thackers daily with oral MSM for about 2 weeks. Nothing to report yet.

 
Date:   3/3/2004 12:08:02 AM
Subject:   updates
Name:   steven 
Any progress updates? Good news , no news? just curious how it was going for you all.

Steven

 
Date:   3/2/2004 2:15:16 PM
Subject:   Rzz
Name:   Dick 
No - my email is not Rzz. I just got confused when filling out the Post Message.

My best friend was killed in an auto accident a year ago, leaving a wife and 10 year old daughter. It was a life altering event for many people, especially his wife and daughter of course. My heart goes out to you and them.

 
Date:   2/29/2004 1:05:45 AM
Subject:   rzz
Name:   PDFTD 
Email:   pdftd@yahoo.com 
rzz,
That's very sad,best wishes to all.

Barry

 
Date:   2/29/2004 12:34:43 AM
Subject:   Rzz
Name:   steven 
Rzz, my condolences

All the Best,
Steven

 
Date:   2/28/2004 11:59:36 PM
Name:   2-Cents 
Rzz,
You, your friends and his family will have my prayers.

All the best,
 

 
Date:   2/28/2004 6:06:39 PM
Subject:   to let you know
Name:   Rzz 
Friends,
I just received news a few hours ago that one of my best friends that I've known for 33 years, since I was 7 years old, was killed in a motorcycle accident early this morning in my home Town. I'm in shock, stunned and don't know what to Think. I don't know what made make this post other than I'm trying to take care of some last minute things before I leave. I'm leaving for the airport in about an hout to go back home. I have no idea what his family is doing for funeral arraingments, I know they are devestated. He had a wife and 2 daughters (8yrs and 11yrs). His wife, who is also a close friend, is the one who called and told me. She asked if I could come right away and I've booked the first flight I could get out. Don't know when I'll be back. Depending on how things are, I would think sometime next weekend or the first of next week.
 

 
Date:   2/27/2004 11:41:21 PM
Subject:   kingfish
Name:   Mountain Hiker 
Email:   rldurkin@aol.com 
in your post of 2.10.04 you say your Peyronies Disease HAS IMPROVED. I m new into this. How did you get it to improve? Thank you. 

 
Date:   2/27/2004 5:47:17 PM
Name:   kingfish 
Frank, Scroll down 600 messages and start from the beginning if you really want to know!

 
Date:   2/27/2004 4:53:47 PM
Subject:   ~dq~Powerful Home Remedy~dq~
Name:   Frank 
Email:   franksandyh@adelphia.net 
What is the "powerful home remedy???

 
Date:   2/27/2004 4:25:20 PM
Subject:   curious
Name:   Rzz 
Dick
I was just curious because I always have just assumed everybody did it the opposite Way. Applied the formula when they got home for the Evening. Guess I was wrong, but whatever works best for you is the way you should do it. I would! Also a little curious about your email. I noticed today it was Rzz. Same thing again, it's no big deal and I'm just curious, but you go by Rzz? 

 
Date:   2/27/2004 2:34:37 PM
Subject:   morning application
Name:   Dick 
Email:   rzz 
I'm the one who said I apply Thackers before going to work in the morning. I had not thought about it before, but I guess there are two reasons. It's easier to establish a regular routine in the morning because I don't always go straight home after work. Second, I'm more sedentary at work than I would typically be at home (chores, etc) - so it's easier to keep it in place at work.

 
Date:   2/27/2004 10:21:33 AM
Subject:   Rzz
Name:   kingfish 
Rzz, Glad to hear you put that sski info together . Ill be waiting to see what you have to say....much appreciation

 
Date:   2/26/2004 6:04:07 PM
Subject:   Potassium iodide
Name:   Rzz 
Just wanted everybody who's interested to know I'm ready with what I've learned about potasssium iodide and using it with the Formula. I don't have the time to get it posted right now, but it will be up before the weekends Out.

Got a few other tidbits I think some of you may find interesting too. Including more info on the formula and DMSO. Hope to get some emails and a phone call from some people tommorrow so I can get that info up too, but if I don't I'll still put up what I got.

 
Date:   2/26/2004 5:12:55 PM
Subject:   Steven
Name:   Rzz 
Steven,
It doesn't really matter and whatever works best for you is the way you should go, but I'm just Curious. Why do you use the formula before you go to Work? Wouldn't it be easier to do it when you got home from work? That way you could just wear some old sweat pants and after two hours just head to the bathroom and rinse off. I'm not trying to talk you into something different. Like I said, whatever works for you is great and that's what you should stick to. I'm just curious is all. 

 
Date:   2/26/2004 5:06:49 PM
Subject:   MB
Name:   Rzz 
MB
Glad to hear the smell has gone away Somewhat. It usually does after a month or So. However, don't expect it to completely go away. Remember if you don't smell it doesn't mean there's not a smell still there. Find a good friend and ask them from time to time if they smell it. Actually the oral MSM(Excelsa) will help a little with the smell. Take it with a glass full of juice of your choice. You just pour the required amount in the juice, mix it up and drink it down. If you don't know, the smell also will come from your body as well, especially after sweating.

About the water and DMSO. First, if you are using Jacob's DMSO there is no need to cut it with water because it already is cut with water to Dr. Jacob's exact specification. One of the things I want to touch on again when I speak to Jacob's son is the reason for the DMSO being cut with water. They, both Dr. Jacob and his son, assured me DMSO works better when used topically if it's cut with water. I want to go over this again and get more details. The reason I say this is because it appears some people are getting results when they use good DMSO from somewhere other than Jacob's Lab and don't cut it with water. I'll be back with more on this next week. In the mean time, I'd just keep doing what your doing.

 

 
Date:   2/25/2004 11:35:41 PM
Subject:   APPLICATION METHOD
Name:   Bobrak Karmal 
Got a piece/strip of Velcro at OSH hardware. Cut to length and then sewed a patch of flannel to the strip.
add juice to patch and wrap velcro/flannel around your rod. It doesn't fall off and you can tighten as required. 85 days on formula, plaque is not reduced but erections are improved at night during rem. I use Clinic Services DMSO - 99.9% pure. Freezes at about 65 degrees. I have had to thaw in hot water. Phone no. for DMSO is 800-354-7346

 
Date:   2/25/2004 6:31:28 PM
Name:   Jebb 
Jacob's formula states 70% and the remaining is mineral water. It is already watered down

 
Date:   2/25/2004 11:24:47 AM
Name:   Dick 
Email:   steven 
I'm not sure how the DMSO makes you smell (I've heard it does, but I think it is difficult to detect on yourself), but the cider vinegar can definitely smell. If you're not careful how you contain it, the stuff permeates your underwear and stays with you (the oil holds it). I apply the wrap before I go to work in the morning and remove it a few hours later. I do little cleanup when I remove it to minimize lingering odor. By the way, I use a condum to cover/hold the pad, as suggested by someone on this thread a long time ago. It does a pretty good job of containing the formula, much better than plastic wrap that I first used. Condums are about 50 cents each when you buy them in bulk.

 
Date:   2/25/2004 10:34:59 AM
Subject:   Smell
Name:   MB 
Rzz-

The smell seemed to have settled down. I do taste it every so often. I do pop breath mints and use a little cologne now. The people that noticed it before don’t now. I use Nature Gift because it is the purest out there. What is interesting is that it does not really smell bad right out of the bottle. Again, think that has to do with purity.

I am not taking anything oral. Just following Thacker’s formula. I do it at night for two hours.

I am still unclear on the DMSO and water concentration. I did start out diluting by 30% with water and it helped with the burning. Now I have reduced down to 10% . I did see your post about Dr. Jacob saying water helps with absorption, so winging it.

Any suggestions on controlling smell will be great. I also think it depends on what and how much I eat throughout the day.

Thanks.
 

 
Date:   2/24/2004 10:27:03 PM
Subject:   JC
Name:   steven 
Good luck, JC, nothing like hope, makes you walk a little ligher, keep us posted.
I have a general question for anybody. When you guys mention the smell associated with the thacker's formula, does it stay on you even when you aren't wearing the wrap? I work in Sales and that would be a problem, along with my recently acquired Peyronies Disease bad attitude.
Steven

 
Date:   2/24/2004 8:43:51 PM
Subject:   Gun oil patches
Name:   JC 
Gun oil patches, or gun cleaning patches (whatever you want to call them) are just perfectly cut squares of cotton. Don't get the pre-oiled ones. The Hoppes 9 patches come in a box with several different sizes that are ideal for this application. You could cut your own pieces of flannel, it doesn't matter. Gun cleaning patches are designed not to leave fibers in the barrel of your rifle and yet apply the oil or solvent evenly to the surface. They soak up a lot of liquid for their size so they seem to be an effective and convenient delivery method for our purposes. You can get them at any Sports Authority or Wall Mart.

This is my dick and this is my gun.
This one's for fighting and this one's for fun...

~JC~

 
Date:   2/24/2004 6:49:13 PM
Name:   Red 
I read about the great progress you guys were having with this treatment on another medical forum. I just finished reading this great thread. WOW! Have you guys recently read the entire thread? There are dozens and dozens of guys reporting dramatic results! The other forum was discussing the fact that the verapamil makers in Texas are taking a hit because of this treatment. It seems this info is spreading and there are many guys trying this treatment and seeing results! I am going to order my dmso tonight and start the treatment as soon as it arrives. I pray I have results like some of you lucky guys have listed!!
ThANKS
RED

 
Date:   2/24/2004 6:17:57 PM
Subject:   progress
Name:   Patrick 
hey everyone....i have some news to share...i have started taking natto, adding that to my application of thackers formula now.....i started with three nodules..though one was very small...and quite a bend or arc upwards when erect, and as i have seen others post, a bit of a hinge effect at a weak spot....i now have two nodules and they are MUCH smaller than they were only two weeks ago....i am unsure to what extent the angle has improved, but at times it seems significant and at other times seems slight....though i always had a bit of bend and torsion to one side, intercourse was never at all a problem, but the peyronies changed all that to an extreme arc upwards.....i am hoping to see progress on that next. i am also having great morning erections again.....i hadn't really noticed how much that had waned before..but it seems to be on the rebound.
i will keep you all posted.
regards,
patrick

 
Date:   2/24/2004 5:34:03 PM
Subject:   Question for JC
Name:   kingfish 
I dont know much about gun-oil patch. Is that safe??

 
Date:   2/24/2004 5:28:54 PM
Name:   John 
Thanks JC that was a great post! I wish you the best! I am seeing some mild results with the thacker formula as well. 

 
Date:   2/24/2004 5:28:00 PM
Subject:   JC
Name:   kingfish 
Wise Words from a Wise Man...

 
Date:   2/24/2004 5:14:36 PM
Subject:   Application Method
Name:   JC 
Hello All,

I wanted to address the question of application method. I've been on this forum for a little while but I have other health problems that have taken attention away from this one (I'm really F^@%ed up). I have only been using the Thacker formula for a short time but it does seem to softening the plaque and reducing it somewhat, although not significantly. I am using the FWI DMSO and am getting ready to order the Nature's Way stuff ASAP now that I am hearing better things about that. Application was a difficult thing to get down though so here is the final method I have been using after much trial and error:

In order to mix the formula I use three separate 10cc syringes and draw the liquid up to the 1, 2, or 7 mark depending on the liquid. I then squirt each one into a small glass bowl and mix well with an eye-dropper. I never pre-mix. Whatever I don't use for that application I throw out and make sure to wash the bowl so that the mixture does not evaporate and permeate the air in my bathroom. DMSO evaporates very easily and who knows if breathing it into your lungs could do long-term damage.

I use a gun-oil patch and soak that in the Thacker formula. I place the patch on my dick using tweezers guided with the eye dropper. I then wrap a piece of ACE bandage around my dick and use the included clips to keep it tight. I find it stays there quite well even with a certain amount of physical activity. Using plastic of any kind seems very unwise to me. I say this because plasticizers contain dioxins which mimic estrogen in the human body. I don't need chemicals of any sort affecting my hormones, and who is to say the DMSO is not carrying it into my blood stream?

I have been talking with a friend of mine who is a chemist and he says he believes the formula is a logical application. He is somebody who I would trust with my life so I trust his judgment. We are continuing to discuss this and if any relevant info develops I will be sure to post it. I am also giving him this link and trying to get him to read over the posts to develop some critical questions and possibly improve the methodology scientifically.

I have also been sold on the idea of taking something called Serrapeptase. This is is a proteolytic enzyme, an anti-inflamitory agent isolated from the silkworm. It has been shown to be almost 90% effective in the treatment of Fibrocystic breast disease and has been used for reduction of arterial blockage and elimination of varicose veins. Before I had the Thacker formula up and running I was using this and it did seem to make a difference in erection quality. I take 15mg/dose once a day for now. It must get through the stomach into the intestine in order to be effective so it is important to take enterically-coated tablets on an empty stomach all at once.

I have also been wondering about the possibility of using anti-oxidants to reduce the free radicals that may be causing build-up. I am not well versed on anti-oxidants and have just begun to think about this, but it seems to me that it may be worth a shot to help the treatment along. If anyone has input on this I'd be interested. I also intend to start taking the Jacob's Lab Excelsa Oral Solution in conjunction with the aforementioned treatment.

Someone mentioned the "shotgun approach". I think this is warranted. We are not scientists trying to isolate a cure. We are all self-experimenting hoping to find a solution to a very grave (and emotionally disturbing) problem. Using varied methods may skew the data but it also may lead to a break-through. However, I think Thacker's original formula is a reasonable approach to this disease, especially in severe cases like mine where the disease seems to be progressing, not stabilizing.

One note on my story: My Peyronies Disease was due to trauma. Some doctors have called it an "internal penile fracture". It happened during intercourse. Most likely part of the tunica was ripped. I felt a sharp pain and was recommended to ice it instead of go to the emergency room which is what I should have done. It became a hardened plaque after a week and has gotten significantly worse over a period of about 4 years. I've lost a lot of size, erection quality, and finally ended up with painful erections and impossible sex. Therefore I am more than willing to go out on a limb. Nonetheless I feel that this treatment is logical and appropriate and is not as radical as a lot of doctors want to make it seem. I have been to several of the best experts in the U.S. (including Johns Hopkins) and I have been recommended by them to get a prostethis. So if this helps me avoid that fate at the ripe-old age of 29 then life will be much better in the long run.

I want to publicly thank Rzz for his hard work on this problem, and I don't care if you think I'm blowing smoke up his a$$. He has done good for all of us and those of us who are grateful should tell him. To others who are whining there is no cure or this is all BS you should stop F^@%ing with desperate men who would love to take THIER frustrated anger out on YOU. You have no right to psychologically drain this group. I consider it to be the epitome of evil to be criticizing such a noble effort because of your own uninformed insecurities. The original poster (Thacker) might still be around to answer questions and help us along if it weren't for this type of behavior. The Thacker formula appears to be helping me and many others and discouraging the efforts of those who are enlightening themselves and sharing this with others despite their own immense difficulties is IMHO a disgusting display of selfish fear. If you take the time to properly try the formula and it does not work you are welcome to report that, but where does someone get off criticizing an effort they aren't even part of?

Apart from that little bit of negativity I have found great hope in this forum and I think many of us will end up with positive results. Coming from a sad-a$$ like me that is a strong endorsement.

BTW, I have done a certain amount of research into injection therapy and I think sticking a needle in your dick is an unwise decision no matter what you are injecting in there. I have actually had it done for testing purposes and it may have done additional damage. The fact is nobody can tell, not even the doctor who did it.

I probably have one of the worst cases on this forum. A small reduction won't do it for me so I hope that in a year's time things will get better. For now I have no intention of stopping the treatment since I believe it is working where there is little alternative. For those that may get discouraged: FEAR PARALYZES ACTION so remember there is nothing to fear but fear itself.

~JC~

 
Date:   2/24/2004 12:06:01 PM
Subject:   DMSO
Name:   2-Cents 
Leeroy,
I am using Natures Gift DMSO which states 99.9% pure DMSO.
Jacob's Labs DMSO seems to be somewhat diluted I think 70% and 50%. I got the tip for this brand of DMSO from TIM on this post who noticed an improvement with a change in the brand of DMSO and so did I. I was not using Jacob's DMSO previously. The brand I was using FWI states that it contains 99.9% pure DMSO and the active ingredients are 90% DMSO. I tested it in the fridge overnight and it did not crystalize/freeze but, the Natures Gift did. Jacob's DMSO
Title: Powerful Home Remedy- Thacker Formula.......Thread 2
Post by: Joshua on September 19, 2005, 07:59:26 AM
Peyronie's Disease Patient Discussion Forum 
 
Topic: "Powerful Home Remedy- Thacker Formula.......Thread 2"
 

Date:   6/20/2004 11:50:40 PM
Subject:   To PDFTD
Name:   Larry H 
Email:   duffer882003@yahoo.com 
Now PDFTD why don't you fess up and tell this man that you really are Thacker and let him do his double blind study. Do you know how long we have been waiting for someone or something like Yieu Lin to come along and do a really great study on a possible Peyronies Disease treatment of promise. And glory glory, if their study is positive then they (WE, who ever the hell "WE" are) will patent the stuff and sell it to all of us for maybe $100.00, $500.00, $1,000.00, doesn't really matter, as long as we are all cured of this disease.

PDFTD, I know that you are a great cult leader and Long Ling his sniffed you out. So I say to you, be man enough to open up to Long Dong, tell him all you know, for he has only our best interest, and our bank accounts as the driving force behind his post.

PDFTD, you have long been my cult leader, but times change and I now must switch my alligence to Ding Dong, or whatever, as long as he gives me 10% off the top. I just hope he is more reliable than my dick.

Your former cult follower,

Larry H

 
Date:   6/20/2004 10:57:22 PM
Subject:   Who we Are.
Name:   Yieu Lin 
Email:   Yieulin@yahoo.com   
The post was not meant to be a kind proposition based upon extensive forum research. Only a general, not in depth, observation of the obvious.

Of course the formula is easy to make and mix... we are not interested in this, only more in depth research which would require personal contact and research notes up to the latest time of revision.

We, are a research group affiliated with Chiba Univ, Japan, in Japan, doing research on Urology i.e. a semi-specific area of ED including Peyronies Disease. Based in Japan because stem cell research is un-restricted here, and we have good pre-liminary results with basic cell therapy, but possibly might be interested in an anjunct cure to use in addition that may help the overall healing process.

My email account waits for PDFTD's contact.

yieu lin

 
Date:   6/20/2004 5:53:31 PM
Subject:   response to Yieu Lin
Name:   Rzz 
Yieu Lin
I really doubt you'll ever be talking to Dr. Thacker unless you know how to use a crystal ball or conduct a seance. Or maybe you could go on that TV show "Crossing Over." Damn man, when you read a book do you skip over pages, because this doesn't speak well of your research skills.

Also I'll give you a little advice. When you want to speak to somebody, the way you wrote your post is not the best way to go about it. I've been fortunate to speak to some of the experts in Peyronies Disease research and medicine and I tell you it took time to do so. Plus, sincere and honest letters as well as phone calls to convince them my motive was good.

In addition, if you want to test the validity of the formula why not just do the test and see for yourself. The formula is very, very easy to mix.

Also, what's with this "patent thing" you speak of. What are you saying? Do you want to test the formula to see if it works, then patent it so you can charge dollars to the people who need it and who could easily make it themselves for just pennies. AH! The almighty dollar! It never fails!

As is PDFTD, I too am curious as to who the "we" is you refer to in your post.

 
Date:   6/20/2004 2:38:08 PM
Subject:   To Yieu Lin
Name:   PDFTD 
Who are the we you refer to in the first paragraph?

If you read the forum and the threads that apply to the Thacker Formula you would know that Dr. Thacker passed away.So much for your research skills and just plain paying attention.It was never stated that he was a Urologist.

Lin,are you kidding me or what?do you read and research before you flap your tounge?Dr. Thacker was the only Doctor in th family.where are you coming up with this crap?Are you on drugs or just stupid?

If you choose not to believe me then DON'T,I DON'T CARE.You are nothing to me.Thacker the grandson of Doctor Thacker wanted his privacy and I gave it to him,so what was said between us is none of your business.

If you and your collegues want to talk to any one you can talk to me.And if you can prove that you are not just some bullshitter then I will contact Thacker and see if he want's to talk to you.I made a promise to him to protect his privacy and that's the way it's going to be,period.

Your insinuation that I am Doctor Thacker is very funny.LOL.Yes there are research notes written by Doctor Thacker but as to weather or not you get them will be decided by Thacker not me.

But you are not going to get a thing until you tell me who you are.Give me an idea of your validity on this forum and I may contact you via e-mail to further validate your claims.

Barry

 

 
Date:   6/20/2004 1:11:00 PM
Subject:   Something of note.
Name:   Yieu Lin 
Email:   Yieulin@yahoo.com 
Directed here by hearing a couple of men talk about the Thacker formula, we took a look, and here's what we see.

In a recent National Physician search within the United States, I could find no physician's by the name of thacker that practice Urology. Some are in family medicine, some in other fields, none in urolology.

All posts regarding 'The Formula' or 'Dr. Thacker' and his long family history of physicians are made by PDFTD, never by the illusive Thacker. Information regarding Thacker, his work, or any type of identifying information is never given. Just promises that, "I have talked to him, that should be enough". All postings are made by PDFTD. (PDFTD would make a great cult leader, "don't ask, just beleive me").

Regardless, because myself and sevaral of my collegues have heard about this formula, we would like to contact Dr. Thacker. Our group is working with private and public funding (semi funded by Pfizer) and our Urology group is anxious to contact Mr. (Dr. Thacker).

So, Dr. Thacker, a.k.a. PDFTD (they seem to be one and the same), we can set up contact information at the email above. We are willing to review and test this formula in a double blind study, and possibly patent this, once validity is established. We will, of course, need Mr. Dr. Thacker's cooperation and all research notes... if there are any. 

 
Date:   6/10/2004 1:06:34 AM
Subject:   Still using ...
Name:   Nemo 
I'm still using ... about 6 months now ... still better erections - but no change other than that. I'm still satisfied that it's worth the trouble, even if only for the better erections.

Nemo

 
Date:   6/10/2004 12:48:27 AM
Subject:   working?
Name:   steven 
Hey All,

How's its going with Thacker's formula, its beens 8 months since it was posted, any correction of curvature?
I know it improves erections, curious about the curvature results. I've been away for awhile, notice ALL the posts have less of a sense of urgency, anger and despair, thought maybe that was a good sign, yes? Can you post good news stories if you have em....

Steven

 
Date:   6/9/2004 11:37:48 PM
Subject:   To Barry
Name:   Ray 
Hi Barry, in one of your previous messages you mentioned you used, as treatment for peyronies, soy isoflavones. I believe the dosage was 50mg at the rate of 3 in the am and 2 in the pm. If this is incorrect please advise. Would you be willing to address the results and the time elements. Also if you have any data that lead you to this plan of treatment. Thanks Ray

 
Date:   5/28/2004 6:23:52 PM
Subject:   to J and the Duprey sx
Name:   Bo 
Hi J

when i began to notice an angle shift in my "friend" well, that puzzled me.........and I usually get into things that puzzle me........
but i didn´t............then when apparent Dick Disfunction became all to obvious i started to check things out......and
finding hard, roapy things where they should not be..........well.it finally got me to this site.

But i´m still 30% out of shape.........
The Hand: well, perhaps from one day to the other or over a few weeks began having knots under the skin an inch below the palm side of my 4th finger, and gradually another knot appeared at the lowest joing of my little finger.
they don-t bother me at all, and , well, perhaps there´s a little shaking motion if i try to hold my hand straight out.....which i now avoid doing.........since i´m 63.....well i don´t want any negative glances comming my way.
My granfather was from england........and from my fathers side........well his family have been hold up in the edge of the state of maine ever since......some boats came over....
i always was led to understand that they were from the "pilgram" group......that survived.
i never have been much into geneology...(?) but my beard was red and my eyes bright blue.............but at about 5 foot 7............i have never given the Vikings much thought..........save avoidence.......

however.........i have been mystified and intrigued by the occurance of hand and dick getting hit by the same type of , well, metabolic, disorder.........like, really strange....
i believe that there is much more unknown about collagen or fiberous tissue than is known......
i would not wait for any correlating information before getting into the "old man´s" technique.............

Essencially, there does not seem to be anything yet..yet... available to dissolve the knots and nodes.....but at least you can begin to get those caverns blood filled and streatched..........maximum effort........

also, it always good to paralelly consider venous or aterial leakage in your best friend..........which is at time another condition which easily leads to poor erections..........
Wishing you good health, and an investigative spirit to help get us back in the game............
Bo
 

 
Date:   5/20/2004 9:00:54 PM
Subject:   reply to Bo
Name:   j 
Bo, they are essentially 2 manifestations of the same pathology. Another is "Ledderhose Disease" of the foot, of which I also have a mild case. "Frozen Shoulder" has recently been associated - and I've had it, too.

They're all instances of Type III Collagen being formed where it doesn't belong. It's been likened to wound healing, but I've hand no traumas to my hands, feet or shoulders. Dupuytren's has been found to be strongly hereditary, apparently originating in a genetic mutation in one of the Viking populations. There is more readily available data for Dupuytren's than for Peyronie's. For example I've read it's very common in Iceland.

When I was first diagnosed with Dupuytren's disease about 6 years ago, the hand surgeon told me right up front that it can affect 3 parts of the body - and he was pretty graphic about it. So when Peyronie's hit me last year, it wasn't a surprise. And the urologist I went to was already treating another patient having both Peyronie's and Dupuytren's.

Why people get different combinations of these conditions is part of the mystery. It's an interesting mental exercise to theorize as to what those parts of the body might have in common, that is causing the formation of the collagen deposits.

Dupuytren's is easier to deal with because we can solve the problem mechanically, at least for a while - i.e. sever the cords surgically and - with systematic therapy - regain functional use of the hand.

What's your hand look like? 

 
Date:   5/20/2004 6:49:47 PM
Subject:   your thoughts on damage
Name:   Bo 
J..I also have the hand abnormality.........I think I got it before the Peyronies Disease, tho I´m not sure.......but no md could tell me what happened to my hand.............clearly, since it was of minor disturbance I did not go looking for trouble with uninformed mds´.........
However I haven´t talked with any one with both conditions....and I also find it highly unusual and atypical that someone get struck with both maladies.......
I haven´t been into "rough" sex and thus doubt that the Peyronies Disease situation is a result of this behavior.
Nevertheless I´ve got a full blossoming case of Peyronies Disease and its getting a little worse as time goes by.
And I do REALLY ponder about the coincidence of the hand and Peyronies Disease.........it just seems to somehow to be a part of the same ? metabolic? diorder.

I´ve been using an inexpensive VED and do think that the workout does kind of reestablish blood chambers towards their initial condition, and this simply makes simple sense. However regarding the very fact of the plaque condition, well this has not changed at all..........granted I haven´t been doing daily workouts with the VED........and probably should......nevertheless the plaque seems to be a chapter apart and unto itself. And its continuing in development.

I write to you only to probe your own analysis and considerations regarding the apparent correlation between the 2 disorders. And, to , ask if you have come up with any information relating to the 2 occurances and what to do about it.
Wishing you the best of great health.........and please have a lot of hope.........

Regards
Bo

 
Date:   5/16/2004 3:33:14 PM
Name:   Archie 
Business Week magazine has an article on stem cell regeneration. The cover photo is of a salamander that is capable of regrowing severed appendages and organs. Scripps, U of Pitt, DARPA and Big Pharma are researching how the salamander regenerates and how that can be done in humans using stem cells.

 
Date:   5/15/2004 11:20:25 AM
Name:   j 
I want to advise extreme caution regarding the VED. I know Old Man and others have used it with apparent success. But - I also have Dupuytren's disease and it is well established that attempting to stretch Dupuytren's tissue is counterproductive. When I was diagnosed by a hand surgeon, one of the first he said was to forget about stretching, saying "it's been tried".

My own personal suspicion is that Peyronies Disease isn't a single disease. I think those of use with both DC and Peyronies Disease may have something different than those who have Peyronies Disease as result of trauma, or some other cause. The tissue changes may be the result of a different process. Just my uneducated opinion.

 
Date:   5/15/2004 10:35:10 AM
Subject:   response 2
Name:   Rzz 
I do not have any doubt about the validity of the VED for helping some who suffer from Peyronies Disease, but to be honest I'm a little afraid of It. My concern is without very good and exact execution it may cause more Damage. Possiblly more tearing, which may result in more scaring. I'm concerned if not done exactly right, the soft healthy tissue that is attached to the scar will tear, split or seperate before the nonpliable scar tissue will stretch. Those who use it and have been shown and taught precisely how to use the VED I'm sure are OK. However, those who just buy one and start going at it should be VERY, VERY careful of causing further damage. That's just my thought. 

 
Date:   5/14/2004 9:48:12 PM
Name:   yo 
That sounds good. I think I'm probably a 0.5 to 1 on that 0 to 10 point scale, at this point. I'm going to start giving the formula a try again, and when I get the money, I'm going to buy a VED (vacuum erection device) for therapy as well. You might consider using a VED as a therapeutic method alongside the formula-- I've recently read somewhere that some who use a VED over time start to experience increased bloodflow to the unit in general. Best of luck to you-- hope you get it all the way back to a 10 and show that girl a blast!

 
Date:   5/13/2004 3:04:55 AM
Subject:   Yo ( A response)
Name:   Rzz 
Sorry about that, hit the wrong Key. I'd think as many post as I've made I wouldn't do that, but to my amazement I still Do.

Yo,
Yes, it has been 6 months since I started on the Thacker's Formula and i will give you an update. however, I need to tell you a few things. 1) In the first 4-5 weeks of using the formula I was using "Jacob's Lab DMSO 70/30." Which we all now know is not the type to use. Not only that, for approx. the first 2 weeks of that period I was adding another 30% water to it, which decreased the DMSO even more drastically. Although it may have helped slightly, I really don't count that has actually being on the formula. If you're not doing it right, then it can't be counted when gauging the results. 2) There have been small periods here and there of 2-3 days when I did not apply the formula. I was out of town for a funeral for 6 days when I did not use it and another time fishing in Canada for 5 days. All together I'd guess about 3 weeks. So that adds up to about 7 weeks of not using it or not using it properly. So with that said, I've actually been on the formula or should I say used the formula the way it was intended for a little over 4 months. Also, remember mine was not a problem of curvature or pain, but one of erection quality. That was what I was really seeking to improve. On an erection scale of (0 to 10), 10 being the rock hard erections you got when you were 18 and 0 being completely impotent, I'd say before the formula I was about a 2.

Here's where I'm at now: In the first couple of weeks, even on the weak formula I noticed slightly better morning erections. After roughly 7 weeks, the morning erections were considerably better, on the scale maybe a 4. As the days passed there were a few mornings that if the opportunity were there I truly believe I could have made penetration. How long it would have lasted I don't know, but I believe I could have penetrated. On the scale I saw a few 5-plus. Before the formula that never happened.
Somewhere into the third month things seemed to stall and improvement ceased. I thought "crap!! that's it. It's ran its' course and it's not going to get any better." However, I kept using it. Well about 3 weeks ago, it kicked into gear again and I started seeing improvement. Morning erections, when I get them are always at least a 5 everytime and I think are getting stronger. Here's a story and the real kicker! Last Friday I was out with this girl I see from time to time. I still don't know why, maybe wishful thinking, but an hour after dinner I took a Viagra. A couple hours later we were slow dancing at this night club and she was looking good, REAL GOOD! All of a sudden I felt myself getting a slight erection. I couldn't believe it. Toward the end of the song she looked at me and said it looks like your glad to see me. I just smiled and said I was. If she only knew how my insides were jumping for joy! So in conclusion, compared to what I was before, I've seen good results. I still have a ways to go though. Will it keep getting better? Will I lose what progress I've made? I don't know the answer to those questions. But I know I will keep using the formula until I see something to make me stop. That's where I'm at right now.

As for your other questions. I use what the formula calls for in a wrap. WHITE and only WHITE flannel cloth. Go to any fabric store and they'll have it and it's cheap too. I do my wrap at night. First I just use WARM, not cold or cool, but WARM soap and water for a quick wash and COMPLETE dry, then use a 2"x4" soaked wrap. Then another wrap that has NOT been soaked and is slightly BIGGER than the first(it seems to stay in place better when I do this and it catches any excess that may drip from the wrap). I then use a piece of kite string and LOOSELY but snuggly tie it. The whole process from wash to tie takes about 4-6 minutes. Put on a baggy pair of old shorts and go about doing what I want to do. No exercize, but everyhting else is fine. I waxed my car last Saturday with it on and when I took it off it was fine.

As far as using it in conjunction with l-arg + viagra + pentox, that I don't have an answer for. I would be very careful about mixing things you've not researched. Especially mixing Viagra & Pentox, but I just don't have an answer for you on the last question. Good luck. 

 
Date:   5/12/2004 5:44:27 PM
Subject:   To Dick
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Hi,
I actually did not answer your question directly to you and I apologize for that.I incorporated your question in a questionaire I sent to Thacker while I was working on the formula,so you were on my mind.The answer to your question is YES.Please go to the following thread for a comprehensive formula revision.And you will see that your question was addressed there.Including this thread it is the 16th thread down.

Peyronie's Disease Patient Discussion Forum

Topic: "Thacker Formula-Re-vised 05/03/2004"

Good Luck,
BTY,
Barry



 

 
Date:   5/12/2004 4:31:35 PM
Subject:   question for Barry
Name:   Dick 
I don't recall seeing your response to my question whether the formula could be mixed ahead of time. Maybe I missed it.

 
Date:   5/12/2004 2:44:15 PM
Subject:   Thackers Formula
Name:   testme 
PDFTD - thank you for all of your help and your honesty.

I personally cant understand the reasoning behind people who are angry with this formula and the people behind it.

If you wnat to try it then do so - If you dont want to try it - then do not.

You dont get angry with McDonalds if you dont like thier cheeseburgers you just dont eat them.

The above is a simplistic attitude applied to a very complex situation (Peyronies Disease and home remeies) however being angry at everything doesnt help yourself or others.

Please support PDFTD and others who are trying to support you!

 
Date:   5/12/2004 1:01:43 PM
Subject:   Response to Annon
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Hi Annon,
Your welcome,and thank you.No actually,using a wrap a second time is not a good idea.The second wrap just won't do anything.Each wrap MUST be fresh.

In a second wrap the biggest concern is that you are not using a wrap that is clean and fresh.Sterile conditions during the second use will have been lost.Plus the second time used the wrap will have DMSO and ACV that has lost their potency almost down to nothing,and the wrap will have been contaminated from the first use.Sorry, I know that's not what you wanted to hear my friend.Good Luck.

Best To Ya,
Barry

 
Date:   5/12/2004 9:55:43 AM
Subject:   Wraps
Name:   Annon 
Barry,
Thanks for your work on this subject. In the early days of this formula many surmized that it had to be made up each time it was used. In light of Thacker receiving this formula premixed from his grandfather, would it be prudent to reuse the soaked flannel wraps several times as this would reduce the amount of ingredients needed.

A Thread Veteran

 
Date:   5/11/2004 11:09:53 PM
Name:   j 
Sigh.
 

 
Date:   5/11/2004 10:47:25 PM
Subject:   Phil
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Doctor Thackers Journals were offered to me, not for public reading.The contents of the journal was what lead him up to the formula we now have,so it's days gone by.You were not privy,and will never be,to the conversations thacker and I exchanged.He intrusted me with privacy and he is damn well going to get it.I will not breach the trust thacker had in me for you or anyone else.If you want creditibility about the formula you can come to me,If you don't consider me a credible source of info, knowing that I talked with thacker, who do you think is going to satisfy you, Doctor Thacker?This formula is simple enough for you to research and find any answer you need.The method of application is the only thing that you need to be concerned with.

THERE IS NOTHING IN THOSE JOURNALS THAT WILL MAKE ANY OF US MORE CONFIDENT IN THE FORMULA,AND THERE IS NOTHING TO LEARN.AND THACKER WILL NOT POST THEM ON A FORUM.AT BEST THEY WERE FOR MY EYES ONLY AND WOULD HAVE NEVER BEEN POSTED TO THIS FORUM.AND PHIL,DON'T MAKE DEMANDS ON ME!!!!!!!!

If you have questions ask and I will provide.I think I laid it all out pretty well to understand.

Barry

 
Date:   5/11/2004 9:55:36 PM
Name:   Phil 
Well I am sure you may not have wanted to view thackers research journal, but I am sure a lot of us here would. It would certainly lend credibility and answer questions we have about the formula and its details. Seems strange for one who demands so much of treatments and the research backing them to just nonchalantly pass up the actual research from the creator like that. I for one would like to see what doctor thacker had in terms of research, and I am sure others would agree as well. LET US SEE DOCTOR THACKER'S RESEARCH AND LEARN MORE ABOUT IT! IF ITS READILY AVAILABLE FROM THACKER, LET IT BE POSTED FOR ALL OF OUR GOOD!

 
Date:   5/11/2004 8:04:51 PM
Subject:   Message to j
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Hi,
I don't want to get in between you and Davi so I will have little to say in the matter of your statement to him.I hope thing work out for u 2.
My feeling is the same as thackers,use it,don't use it,it's up to you.But Doctor Thacker did in fact leave Journal of his research on this formula,thacker offered them to me for reference if I wanted them but with the treatment doing as well as it seems and my having done so much research on all the components(least not forget rzz)I did not feel the need to view the journals.

I would suggest that you research what medicinal properties ACV has,you will be overwhelmed.DMSO as well,it's amazing stuff.I would ask a question of you that does not require a reply,can you name anything in medice that has no method of action.I can name dozens of things.Just think with an open mind.I would like to see you or any one on this forum have a treatment success story,it's inspiring to all,but don't use the formula if you don't want to.If you want a better understanding of it contact me and I will throw notes at you until your eyes cross.Good Luck at what ever you do.

BTY,
Barry

 
Date:   5/11/2004 6:22:43 PM
Subject:   testimonials
Name:   j 
Davi - that's interesting information, thanks. Some of the reports are more credible than others, and I'm still highly skeptical, but there is enough there that one can't just dismiss the thing out of hand.

What's missing for me is what the medical people call "method of action", i.e. the legendary "Dr. Thacker" left no explanation of how this formula is supposed to work, or how he arrived at it.

I have Dupuytren's contractures too, and that tissue is much more visible and easier to evaluate than Peyronies Disease plaque. It's certainly not just a calcium deposit - it's living tissue gone bad at the cellular - possibly genetic - level. And it's hard to imagine that something like apple cider vinegar is going to selectively dissolve or "reform" it in some way.

 

 
Date:   5/11/2004 3:31:44 AM
Subject:   Rzz?
Name:   yo 
Rzz? How's your condition after about six months (I believe) of your using the DMSO formula? Are your erections of improved strengh/duration? If so, by how much.

I started using just the DMSO six weeks ago, only to end it after a week, as I was afraid of bad hygiene, didn't have a couple hours a day to soak, wasn't sure of the material to soak in, etc. Could you tell me exactly what kind of material to soak the stuff in and how you wrap it, and also how you're sure your penis is completely clean before slapping on the wrap? I am thinking of doing this treatment in conjunction with the l-arg + viagra + pentox treatment.

 
Date:   5/11/2004 12:57:54 AM
Subject:   Started this on in DEC 2003
Name:   Bobrak Karmal 
Been using this 2 hours a day since Dec, 03. Plaque is Slightly smaller with rubbery tail end. I take L-arginine and a small amount of viagra every so often. It gives a nasty headache. The only real treatment that has worked is manipulation and bending of the plaque to try and make it flexible. I am going to continue the thacker treatment as it make the plaque easier to bend. I have been posting for about 3 years now! 

 
Date:   5/10/2004 10:45:18 AM
Subject:   TO J:
Name:   Davi 
TO J:
I did your work for you. I just scanned through the orginal thread and easily pulled the following coments. There are many many more i just got tired of cuting and pasting Pleae read the thread. It is long but it may be the most importaant read for your Peyronies Disease treatment you ever did! I hope this helps you. This treatment works. Give it a chance. It has reduced the plaque content in my penis by 50 perecent in less than a month.

____________________________________



Date: 11/21/2003 7:33:40 PM
Subject: DMSO treatment
Name: Gephardt
I have used dmso for a month. I have not been frequent at all. I may apply it in the morning about two times a week. I cut it with 100,000 IU of Vit E oil from walgreens.
I have noticed:
1. The One large top plaque about the size of a quarter - softened and then split in half. It reduced by 50%! The dmso is tearing it up!

11/24/2003 9:03:53 PM
Subject: treatment
Name: Don
I am using a treatment plan similar to the one Thacker described with success. I am using dmso cream packed on twice daily. I have noticed an incredible improvement! I started using dmso about 30 days ago. I had a tendon on the top of my member that had a plaque growth along it. The plaque growth was causing my member to curve during erection. I started packing the dmso on it and it broke the plaque up. When the dmso is on your penis and absorbed into the plaque it immediatly makes the tendon more flexible. However, when it wears off the plaque and tendon gets tighter. I noticed over a few weeks the plaque started to seperate and free up the tendon. My curve is about 5 to 10 degrees compared to 35 to 40 degrees before.

Date: 11/24/2003 10:25:57 PM
Subject: plaque
Name: Don
I had two plaques that were solid/connected. They broke up into smaller pieces. A few of the smaller pieces then cleared up altogether. That is the best way I know how to describe it. The whole plaque did not shrink it broke up and then a few of the smaller pieces did shrink.

purity of dmso
Name: paolo
I have been using Thackers formula for about three weeks and have found it to be the only effective treatment so far. The plaque has shrunk and gotten softer. My erections seem stronger and quicker since starting the treatment. I initially bought the dmso from three different sites. Be sure to purchase dmso that is 99.9% pure (not just 99%) as the purer one hardly smells at all and seems to be not as irritating on the penis.

paolo
I have found that Thackers formula has softened and shrunk the plaque. I have found that a purer quality dmso is virtually odorless as compared to one that is less pure. As far as ill effects I am not sure. The only ill effect I have found since starting the treatment is that I have very itchy skin.

To Tony
Name: Billy
I started this treatment for the hell of it on 11-5-2003
I did not have the "break apart" effect that some reported. However, I also noticed the nodules were smaller during treatment but got harder again when the ointment was not on. I increased the treatment to three times a day. I kept a diary on my treatment progress. On 11-9-2003 I went to the three a day treatments. I had one large nodule right in the middle of my penis. It caused a bad bend. I placed packs on both sides and used bandaids to sandwich the treatment packs around the nodule. The nodule started about the size of a large marble (soft). It is now just a pinhead. The pinhead is hard. I can't seem to get rid if the last piece. I used aggressive jelqing with the treatment. The jelqing info came from the yahoo board. The treatment did blister the crap out of my penis. I may have even discolored it in two spots. The bend is gone and there is no pain no matter how hard I have intercourse.

ubject: Results!!
Name: Bond
I AM SEEING GREAT RESULTS with heavy application of "thackers formula", Old Mans VED therapy guidelines, high gamma vitamin E and jelqing procedures learned from Morgan's posts on Yahoo.

The formula posted was like a miracle to me. I used strong dmso. I got sores from the treatment but kept going. I ended up with a light discolored outer scar on my penis but the plaque broke up and the curve up almost is in the past. I am hitting areas in my girlfriend I was not able to touch with the curve.

Name: Arty
I been using the treatment for three full weeks. I am in the eraly stages of Peyronie's Disease. I have noticed a decrease in pain. I also have noticed a softer looser tendon. It seems to have made the fibrosis loosen it grip on my penis. I did have soom buring but it seems to have been worth it. I will update in another few weeks



Date: 12/23/2003 9:24:46 AM
Subject: treatment
Name: Johnson
I have used this treatment for about 20 days now. I started with one long string like plaque that runs the length of the shaft, with one large nodule attached near the base.

The string like sized plaque separated in three places now! The larghe nodule has apparently not changed. I had the string like plaque for almost a year now. Therfore I know for a fact this formula broke it up. It has not yet effected my curve but it is progress! It makes me see some light and hope at the end of the tunnel. I will update again if I see anymore changes. Thanks guys that helped with this thread.

An Update on my treatment using the formula. My plaques have all but gone but I can barely get an erection?? I am going to now quit and see where I am at. I keep the formula on almost 24 hours a day. I fixed one thing but now I have another problem. I pray it temporary.

have had a large marble sized nodule in the middles at the bottom for over 6 months now. No change in shape or erection quality, just the nodule.

I started the DMSO/ACV formula 2 weeks ago applying once a day for 30 minutes.

Since then the pain has gone in the nodule and the size has decreased, however I now have an indent where the nodule is - whats going on, size and pain reduced but now a dent please help?


 

 
Date:   5/10/2004 8:54:26 AM
Subject:   Progress
Name:   testme 
Guys who have been using the formula can your post your progress please:

 
Date:   5/9/2004 8:47:00 PM
Subject:    PS
Name:   Paul 
Email:   RockBoy@excite.com 
PS here's an Australian link with good info


www.msmaustralia.com.au

 
Date:   5/9/2004 8:45:49 PM
Subject:   substitute DMSO for MSM
Name:   Paul 
Email:   RockBoy@excite.com 
Has anyone used MSM as a substitute for the DMSO?

It appears to be less 'dangerous' if you like - added to the fact DMSO appears to be harder to buy esp. overseas - in Australia for example you can't it.

 
Date:   5/8/2004 11:44:06 PM
Subject:   Remedy
Name:   Paul 
Email:   Thomas48@chariot.net.au 
Hi I was thinking about this remedy (properly a bad thing) :) it is accepted P.D. is caused by injury. This is the case for me also checking family history no one has ever had Peyronies Disease in my family tree. I’m no medical wiz to me for plaque to suddenly appear for no reason seems odd and any bruising in the body can from bone. I know that from having bad bruising from playing football. This all supports Peyronies Disease is in fact caused by injury. If this is the cause of Peyronies Disease how can plaque reform? You would have to keep re injuring yourself? To my way of thinking if some one manages to cure themselves plaque cannot re form once it has gone. The plaque has to be gone to release the bend. The only other explanation is the plaque is made so soft it releases the tightening affect caused by plaque hardening. Also finding substances to keep plaques away once it has gone or is reduced, or softened that drug that keeps plaque from reforming wouldn’t it in doing this also get rid of plaque? That it itself would have to be a cure? I hope this remedy does work it appears to be the case for many people here. I hope my thoughts don’t upset anyone that isn’t my intention; I really want to find a cure. Also is anyone here single and should be sexually active (age and good health) but can’t be due to having such a severe bend and impotent? I would like to hear from these people to see how they are coping with not being able to have intercourse therefore find it very hard to find a partner to live with. It is a daunting prospect at having to live alone for the rest of ones life. Anyone in this situation I would like to hear from them please. Thanks

Paul.
 

 
Date:   5/8/2004 9:54:39 AM
Subject:   Treatment
Name:   Paul 
Email:   Thomas48@chariot.net.au 
Hi everyone i think Im starting to understand how to post etc. I very happy to have had a good man write to me bringing me up to speed with this home remidy. I managed to find some DSMO. Having done that the receptionist at the plcae i found DSMO told me the vet had split a small amount of DSMO on himself and it made him feel sick. I didnt buy it without trying to find more information about DMSO. As I got the idea from here and you guys have used it can anyone tell me does DMSO make you feel sick? The DSMO i was going to buy came ina one little hard plactic bottle. It read 100% DMSO on the label. It was made by a firm to treat cattle with shin splints the vet assistant told me. I do no it is used in the Grey hound industry, race hose industry and now and then by some body builders. There snt any DMSO made for humans so i do understand it is the DSMO made to treat animals that is used. i have no problem with this i would do anything to cure Peyronies Disease. I cant find much information here in Australia it seems more readerly avalible in the USA and UK. It seems odd to me it would make people sick i have never heard of this before. Im not in good health right now also Im not very strong that way either. I have kids to care for and dont want to get sick. Can anyone tell me what does DMSO does to you when you apply it to your skin please?


Thanks


Paul

 
Date:   5/3/2004 11:48:24 AM
Subject:   Thackers formula
Name:   Terry 
What is Thackers formula? I can't find any information on it. I have read the entire thread. Please help! Please list the ingredients and how to treat with it. Does it work better than other medicines?
Terry

 
Date:   5/3/2004 11:39:10 AM
Subject:   Can we be mates please?
Name:   Paul 
Email:   Thomas48@chariot.net.au 
Dear Thacker, Hi how are you? Im a Auastralian guy I some how found this place while encoraged to look for a cure to P.D. First of all I cant write or spell well so sorry about that. I have seen how men get real honest and sincere when up agaist it. I saw this a lot while serving in the Army. I tell you what it has sobered me up developing Peyronies Disease. Gee did i get angry or what lol. If having developed Peyronies Disease wasnt enough I have battled Post Trumayic Stress Disorder but Im getting excellant councelling from Veteran Affars for that. Having Peyronies Disease pales all esle that has happend to me into ingsignificance. I need a friend mate I really do. I would like to make mates with you if you dont mind? I dont understand very much about Peyronies Disease. I have seen most other guys on the writting list are pretty smart blokes and know much more than I do. I dont understand many of the terms used lol. I have seen a lot about Thackers treatment? Did you develop it ? Do you mind telling me what I have to do to buy it from you ? Ware can I by it or how do i make it? Im as deserate as a man can be for rectifing this terrible disease? I have a 90 dgree bend right at the end of my penis. I couldnt have sex. I recently was seperated from my wife not becuse of it either she isa good person. Having PTSD caused my seperation i wouldnt get treatment for that I thought it weak and shame at the time i dont now. If having a bend isnt enough I have impotance I think that is right i cant get a erection only partial. I havent had good medical care no one was interested. I should have relied on myself to find out all about this problem. I also am infertile i dont know if that was caused by chemicals encounted during my service or the stress i have lived with for 30 years (PTSD). I dont produce much seamen and have lost that feeling you get while ejackulating. I also havea enlarged prostrate which i only have realised causes me to not urinate properly. i have had many times had protersitis ware my seamen was black when ejaclulating. I was preet scared when that happened. I then have repeading eposeds of bladder infections. It starts out as severe pain in my testicals, then spreads to my bladder, then inside my penis back up to my proterate then around to my right kidney which hasa truma on it. It isnt a cancerious tumor though. Ima wreck arnt I lol. I can tell you the pain is so bad i can only cry. Im allowed to inject myself with morphine for pain until antibiotics kick in. All this I mention to see if you have these problems to? Is it fairly typical to have all these problems with Peyronies Disease? I wonder if Peyronies Disease is stress caused? I have read injury can do it. i can remember my wife did badly hurt it two or so years before Peyronies Disease developed. I have the Vicking curse on my right second litle fiher have you got that? Thats what my doctor called it but it has some Frencj doctors name i cant spell well somthing witha D. I have has terrible stress I didnt know i had PTSD until recently it was left untreated i say that becuse its not my fault and it is very bad to live with. So it could be both what do you think mate? It isbr in my family mum tells me but I should mention i have HAL B27 a typr pf inflation. I read having it causes the Vickings curse and having it makes for having Peyronies Disease. I got the lot LOL. I would love for you to write to me please i need to talk to some one with it. I didnt speak for so long about anything and yhay wasnt good for me. Talking is good i cant shut up now lol. Can you tell me how to buy or make this formular please ? I dont care about politics mate i have learnt the hard way. I have things to really worry about I havent time or the will to upset anyone. I like all people and never judge i leant a lot the hard way. i also leant never to worry about what people think of me or say about me i had to stop that and i did. i can tell you how to do that if you want? I just want to livea happy life what left of it mate i lost most of my life in turmiol with PTSD. I have that in hand now i just got to fix this Peyronies Disease thingo. I hope you will write to me or any of your mates. Ima easy bloke to get along with and can be usfull asa friend as well. I saw this formular in the chemist shop. It is made out of sharp lver oil and some other stuff i will find out for you Im buying some tommorrow. It is for softening and healing scar tissue. I thought it worth a try. i will let you know hownit goes OK? Plkease write will you Im desperate. I cant find my glasses (getting old lol) sio I cant see to well here sorry for the messy letter mate. Hope to hear from you soon.

Best Regards



Paul 

 
Date:   5/3/2004 9:19:58 AM
Subject:   treatment
Name:   Dave 
I also look forward to reading the new information you have. I just started on thackers formula and I am already seeing improvements. better erections, scar softening and no pain

 
Date:   5/3/2004 8:11:14 AM
Subject:   Thanks
Name:   Vick 
Thanks PDFTD I look forward to the updates. This treatment has been a wonderful find for me. I hope the other guys that have tried it and gave up because it was not an instant cure will look at it again. I am seeing results, it works!

 
Date:   5/2/2004 4:10:58 AM
Subject:   Thanks
Name:   steven 
Nice going Thacker & Barry

Thanks !

Steven

 
Date:   5/1/2004 6:02:11 PM
Subject:   Thackers Formula
Name:   PDFTD 
Email:   pdftd@yahoo.com 
I have concluded my conversations with Thacker.He was very cooperative and answered every question given.Most of our communications were in a discussion format and we talked about many things.In the end I sent him a questionaire consisting of under 12 questions,these questions fully completed the knowledge I needed to present a revised version of his grandfathers formula.Some of the forum members had specific questions and these were addressed to thacker in the questions I asked.He was very quick to answer them and held nothing back even though some were personal to him.

In my opinion only,those of us who will benifit from this formula should be greatful that Thacker was willing to communicate with me after haveing been verbally attacked as he was,his option could have easily been screw these guys.i'm outta here.He is a caring and humble man,and asked nothing of me, except that I provide the information that he has added in tandem with what we already have properly, and in an easily understandable format.I will do my best to follow his wishes.But lets not forget Doctor Thacker for one moment,thacker spoke well of him and expressed to me what a fine and loving man,and Doctor he was.

On this forum,where Thacker was abused and verbally attacked I would like to thank him for seeing through the abuse and retaining his desire to help, and not once ever complaining to me about the issue.A Rare man indeed,and I am glad to have made his acquatance.

It will take me several days to re-write the Thacker formula,but I am sure you all wil be pleased with most of it's content.For those presently using it,continue using it with no worries.Also I will post the formula in a seperate topic making it easily accessible and allowing for questions that may arise and discussion to be started from a new and virtually post free topic.

Best To All
Barry



 

 
Date:   4/29/2004 1:14:41 AM
Subject:   Message to All
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Hi Guys,
I have noticed that there are alot of new guys on this forum who have varied interests of the treatment they are looking for,while they are surfing the forum for information eventually they end up in this thread.If you want to read the whole story of the thacker formula then you may be missing the beef.Please go to the thread "Powerful Home Remedy"which is where this thread comes from.It is 656 posts long.The combinination of this thread and the original thread will give you the whole idea behind The Thacker Formula.You will have to go back 19 days to 04/10/04 to find it.Happy reading.

Best To All,
Barry 

 
Date:   4/29/2004 12:04:44 AM
Subject:   Great questions
Name:   steven 
Adam, Great questions! This is great stuff, I have a good gut feeling about this Thacker's formula, although I think its a very long treatment, but better than no treatment at all.

Who knows, we may find a way to speed up the results and get rid of the odor....if you believe, you can achieve....

Steven

 
Date:   4/28/2004 11:24:23 PM
Subject:   ACV
Name:   a 
Apple Cider Vinegar. you can find it in most grocery, drug and health food stores. organic is best, but the other will suffice.

 
Date:   4/28/2004 11:16:53 PM
Subject:   new to the forum
Name:   PD2 
Hello to all and a question directed to anyone able to answer:
What is "ACV" in thackers formula? Where would I obtain it?
I will apologize if this is redundant but I have scoured threads each of the past 3 nights and have been unable to find the answer.
I'm currently using T/V for 2 months with no change in the course of a 2 yr. problem. I'm also taking 1000mg Vit. E for the past 18 months. I have an ultrasound unit and have been using phonophoresis with the T/V about 2 times per week but am going to up it to daily. Does anyone have any experience with phonophoresis and Peyronies Disease?
Barry, as a physical therapist, I have found your postings of substance and usually worth reading until some knuckle head gets you worked up. I will confess to being just a bit more than confused as to why no one seems to post anything about the success of the thacker's formula, however.
Have I just missed those comments in my reviews?
Thanks.

 
Date:   4/28/2004 3:23:04 PM
Subject:   Questions to Thacker
Name:   Adam 
Barry,

Would you be so kind as to ask Thacker the following questions:

1. You mentioned that you have used the formula for a year. Can you say what was your condition when you started, what was the result, and most importantly, when during the treatment did you start seeing results?

2. How old were you when you got the Peyronies Disease? (I am wondering if you had the age related, a major trauma related or a congenital condition at a younger age).

3. Did your grandpa ever publish anything regarding his treatment of Peyronies Disease?

Thanks

Adam

 
Date:   4/28/2004 7:57:34 AM
Name:   Vick 
PDFTD, Keep us updated. Keep up the good work. Thackers formula is not a miracle cure but it does have a place in treatment of Peyronies Disease. DMSO has a tremendous amount of research backing it. I am excited about hearing more from you about this.

 
Date:   4/28/2004 5:42:41 AM
Subject:   Barry - Keep up the good work
Name:   Richard ( the Brit ) 
Hi Barry

Thanks for your posting, I think the Urologists are probable right ( most of the time ) in that they will have seen many others with 90 degree bends for who vaginal intercourse was impossible. Factors such as position of the bend on the shaft, direction of the bend, degree of associated pain, psychological attitude , degree of co-operation from partner, partners anatomical suitability etc etc could all preclude vaginal intercourse with a 90 degree bend.

I was perhaps fortunate that my bend was a simple upward bend with little associated pain and no calcificaton. Had my geometry been different I can well believe that vaginal intercourse would have been impossible e.g. for a sideways 90 degree bend it must be even trickier although I would not rule that out.

I have to disagree with Bobrak Karmal in that I believe the vagina accommodated my shape rather than my penis conforming to the vaginal "tube". I say this as full penetration was possible immediately on insertion which was often done with a rigid erection. To conform to "tube" shape there would have had to be an immediate partial loss of ridgidity on insertion which is just not a credible scenario.

We can only speak from personal experience and belief in the accuracy of scientific papers, and the word of others ( from this forum or elsewhere ) and as with everything we read or hear there are very few totally dependable sources of "the truth, the whole truth and nothing but the truth".

I was , as you know, originally very reluctant to post on this forum as there are too many inappropriate postings. It was in no small part down to your contributions and those of other sincere forum members that my reluctance was overcome. I am delighted that I have contributed as I feel I have been able to help others who have been through the surgical option ( Deano and Meg's boyfriend to name but 2 ) or are contemplating it, and also found the process to be theraputic for me. It is not the sort of subject you ( well I anyway ) can bring up in casual conversation with just anyone and the opportunity to get it off your chest with forum members has proved to be a theraputic and unexpected bonus for me.

To you and all the other sincere posters I say a heartfelt THANK YOU. Keep up the good work in searching for the truth and the ways forward for all Peyronies Disease sufferers.

Richard ( the Brit )

 

 
Date:   4/28/2004 4:35:15 AM
Subject:   Thacker
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Hi All,
Thacker has informed me today that he will not be posting to this forum.He and I agree with his decision.His reasons are of a personal nature and I agree with him.

Any and all necessary communication to or from him will happen through me. Hopefully the Formula and any changes made in regard to it's composition,use,and Misc.information will be made public soon.Please be a bit more patient.And as I stated in another post,the current formula is safe and effical,so there is no reason to discontinue it's use.

Barry
 

 
Date:   4/28/2004 2:00:55 AM
Subject:   Thoughts and stuff
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Richard (the brit),
This conversation of vaginal intercourse with a 90 Degree penile curvature is quite interesting.Never having reached a curvature to that degree,(mine was 50 Degrees)and never having read a post of someone who had such a curvature,plus reading studies and reports written by Doctors who said that a 90 degree penis will not allow natural intercourse to occur,was of course where I drew my conclusions from.Why Doctors would make that statement all knowing that it was not accurate confounds me.But for that matter much of what I read I take issue with.It would be nice to read a report that is written by a Urologist that does not conflict with the writings of another.

I would like to say that I am all knowing but that surely would be untrue.But I give it my all.Often in our research we find that it becomes necessary to fall back on good ole common sence in our efforts to wade through the mystery of differences of opinion of those in whom we are expected to look upon as experts.I find that I become more educated speaking to someone who has "been there done that" then frustrating myself by reading reports and studies authored by men who can't agree on the same issue.

I would rather find that I am wrong on any given subject and compensate for my error then go on believing somethihg that is untrue.I,like yourself,disseminate information to others,and incorrect information serves no one.

Thank you for the post(s) that allowed me to see my error in fact.I hold those,who like myself,try to keep the forum members well informed and educated, to a high standard,with that in mind, I have to comply to the same standard as well.

Understanding the dynamics of intercourse with a 90 degree curve is not rocket science,But I am glad that I did not have to learn from your experience.As I wrote in a recent post the lenght of the penis,location of the curve and the depth of the vagina surely determines the ease at which sex is possible under these extreme conditions.

You might find it interesting that you were the topic of a conversation I had today with a forum member on the phone.Your story is very interesting in that you have been through so much and had such a degree of success in how you treated your condition.Going from a 90 degree curvature to straight is very rare.You are a very lucky man and your wife a happy gal for sure.I told my wife that you are the poster child of how a surgical procedure should end and with what you have gone through in mind,she agrees.

Would'nt it be great if we could read posts that are as positive as yours?I am extremely happy for both you and your wife.Til next time,

Best To Ya,
Barry



 

 
Date:   4/27/2004 5:42:26 AM
Subject:   90 degrees
Name:   Richard ( the Brit ) 
Hi Barry

With a 90 degree bend of course you have to go carefully. In my case the degloved bend during surgery was found to be 110 degrees - only the foreskin tension prevented that being apparent outside the operating theatre.

The process required plenty of foreplay to relax the wife and lots of lubricant.

At that stage I had lost about 1.5 inches in length ( now mostly regained by very gentle post-op use of a VED ), so as I was only average length before Peyronies Disease, length was not a major issue.

At that time full erections were not able to be maintained for very long, so penetration had to be done whilst erect and it is quite likely that there was some subsequent loss of ridgidity ( and hence degree of bend ) after insertion. However full pentration was possible on insertion without any discomfort, let alone damage, for my wife.

The strangest thing was that after surgery she had some discomfort due to deeper parts of her vagina being reached for the first time in years. This was unexpected but only lasted a couple of weeks.

Still smiling at being straight

Richard ( the Brit )

 
Date:   4/27/2004 4:52:33 AM
Subject:   To j
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Hi again,
For shits and grins I had my wife read the report without any preconceived ideas or thoughts given by me.She noticed 5 inconsistonsies(sp)on her own.With a little bit of suggestion from me she found 2 more.Her reaction and comments will not be repeated on this forum.So I would like to suggest that we agree to dis-agree on this matter.I do however completely agree with what you said in the last paragraph.Amen to that brother.

Best To Ya,
Barry

Damn,we got through all that without calling the other an a$$hole. There is hope for peace on this forum after all.
Take care. 

 
Date:   4/27/2004 4:23:06 AM
Subject:   Reply to Bobrak Karmal
Name:   PDFTD 
Email:   pdftd@yahoo.com 
Hi,
Intercourse with a 90 Degree penile curve can most assuredly be possible,to this I agree,Urologists say it's not possible as I say I have read.I would have to dig deep into my document program folders to see what the specifics are to that statement which is not worth my time to do so.

The only logic that I can see that makes any sense is that while stuffing a penis with that degree of curvature into a vagina a few thoughts of concern should be concidered,(a)the lenght of the penis(b)the location of the curvature,this is relative to the ease in which the penis enters the vagina and the actual act of sex and how difficult it can be.

Another consideration that must be suggested is the vaginal cavity of each woman is different.Although the vagina does stretch to accomidate the penis no two women are similar in the size of the cavity itself.So the size of the penis and the size of the vaginal cavity are relative,and more so when the penis is curved to that degree.The resulting event is two fold,the woman can sustain vaginal damage,and /or the penis can be furthur damaged as a result of forceably being straightened by the vaginal walls.another factor exists,while enga
Title: Re: Powerful Home Remedy Archived from BTC
Post by: nick on September 19, 2005, 10:08:07 AM
Wow great work Joshua , thank you. It's nice everything right there and not all messy. You guys rock.
Title: Re: DMSO and DMSO based Solutions
Post by: nick on September 20, 2005, 08:24:05 PM
I have been using my variation of the Thacker's formula for about 2 1/2 weeks now. Today at work having a really crappy day. I got spontanious wood. I don't know if it has any thing to do with the formula but things are feeling pretty ggod down there. I may even try to use it soon.
Title: Re: DMSO and DMSO based Solutions
Post by: jess99504 on September 29, 2005, 10:54:36 AM
Hey Barry. This is Terry form Anchorage... Does that formula really work is there any hope?? Tried Emu Oil and Vit E the only thing that did was make my skin soft. Besides it felt too good rubbing it in!!
You can e-mail me here at work also Terry.Cunitz@med.va.gov
Title: Re: DMSO and DMSO based Solutions
Post by: Joshua on September 29, 2005, 11:32:33 AM
Jess:
also read the home remedy thread. It has about 1000 posts that discuss the thacker formula.
Title: Re: DMSO and DMSO based Solutions
Post by: Barry on September 29, 2005, 11:41:21 PM
Hey,
It's been along time Terry. For the members to see I will answer your question here on the forum. I am going to contact you by e-mail so we can talk as well.

Yes Terry, Thacker formula does work. Like every other treatment RX or alternative it seems to be pot luck if you will be the one who has efficacy, and if so to what degree? I have heard from some that they had nodules that the Thacker formula melted away before their very eyes. On the other hand some have reported the formula as a dud. With the cost of the ingredients being so low it's worth a try.

If we can get that silky soft smooth tool of yours straight, you will be the talk of Anchorange amoung the ladies.

I'm going to post the formula on the PDC web site in the next 24 hours for anyone to read if they want.

Regards,
Barry
Title: Re: DMSO and DMSO based Solutions
Post by: Barry on September 30, 2005, 01:08:24 AM
To All,
The Thacker formula has been placed on the Peyronies Disease Coalition web site for you all to read as of Thursday 09/29/05 11:45 pm cst.



Barry
Title: Re: DMSO and DMSO based Solutions
Post by: Joshua on September 30, 2005, 12:42:55 PM
To All,
The Thacker formula has been placed on the Peyronies Disease Coalition web site for you all to read as of Thursday 09/29/05 11:45 pm cst.

The site url is  www.peyroniesdiseasecoalition.org

Barry
That is a very nice presentation of the home remedy treatment AKA Thacker formula. Great work Barry. I encourage members to read it.
Joshua
Title: Re: DMSO and DMSO based Solutions
Post by: nick on November 14, 2005, 09:57:06 AM
I just wanted to give an update on my variation of the thacker formula. So far I am still pain free, the plaque nodules are smaller and I now have about a 10 degree reduction in curve. I am taking neprinol, msm, a multy V and using the thackers for about 2 hours 5 to 6 nights a week. I am blown away. I was able to have sex on Friday with no pain or discomfort during or after. There is still a curve but I'm hopefull that I will continue to improve.  Now that the curve is reducing I am starting to dvelop the "hinge efeect" that tohers have talked about and a bit of the hourglass shape. It is more narrow at the base. 
Title: Re: DMSO and DMSO based Solutions
Post by: learn4life on November 28, 2005, 08:04:33 PM

Hey folks, hows things everyone?

I got the L-Carnitine from Puritan website and Im abit
excited of its arrival ;P

What would you guys pick from the following :


http://www.ihealthtree.com/dmso.html


Is 70% pure best or maybe 90%?

What about Oil versus cream??

Has anyone bought from this website before?

Hey NIKK if your reading..? How is your Peyronies Disease getting on?

Any success with the Thackers?

BTW Nikk I have been on the Neprinol 3x3 a day for a week now...
I dont think I have noticed any changes but will keep it going for a while longer.

The 100% cure will come one day...  ::)






Title: Re: DMSO and DMSO based Solutions
Post by: Joshua on November 29, 2005, 09:52:53 PM
What would you guys pick from the following :
http://www.ihealthtree.com/dmso.html
Is 70% pure best or maybe 90%?
What about Oil versus cream??

I would pick the listed Dmso Liquid, 99.9% Pure Dmso, Unscented, 8oz,
Good Luck!!
Joshua
Keep me posted I am very interested in DMSO.
Title: Re: DMSO and DMSO based Solutions
Post by: phil on November 30, 2005, 10:56:23 PM
MY specialist never mentioned DMSO, however my GP did when I went for my physical.   Are there any risks to using DMSO?  Has anybody had a bad reaction?
Title: Re: DMSO and DMSO based Solutions
Post by: Hawk on November 30, 2005, 11:51:42 PM
Phil,

There are risks.  I know it is a lot, but there are 1000 posts under "Powerful home remedy" on this forum in addition to this topic.  I would not use DMSO until you studied that topic and this one in detail.

The information is here, the challenge is your's  ;)
Title: Re: DMSO and DMSO based Solutions
Post by: learn4life on December 01, 2005, 02:28:30 PM
I just wanted to give an update on my variation of the thacker formula. So far I am still pain free, the plaque nodules are smaller and I now have about a 10 degree reduction in curve. I am taking neprinol, msm, a multy V and using the thackers for about 2 hours 5 to 6 nights a week. I am blown away. I was able to have sex on Friday with no pain or discomfort during or after. There is still a curve but I'm hopefull that I will continue to improve.  Now that the curve is reducing I am starting to dvelop the "hinge efeect" that tohers have talked about and a bit of the hourglass shape. It is more narrow at the base.  

Hey Nik ! Thats awesome news :) That must be the best feeling to be able to enjoy sex the
way it should be ... PAIN FREE Woot !! ;)

P.s Nik would you say it is best to massage the formula in or is it better to leave it on for a few hours?
Title: Re: DMSO and DMSO based Solutions
Post by: jess99504 on December 01, 2005, 05:41:25 PM
I have thought about using DMSO, but I in the medical field and am around the public all day. I hear that it causes you to smell?? It that true. What about the unscented stuff??
Title: Re: DMSO and DMSO based Solutions
Post by: Delafoo on December 12, 2005, 11:28:16 AM
Posted: Mon Jun 27, 2005 3:36 am      
 
Guest

 It's dcaptain (sorry, I'll email you Hawkman about this, but just wanted to post again first). For those of us not in the know, what's DSMO?

Thanks.
 
 

Having just finished Organic Chemistry, I too was wondering the use of DMSO, as it is frequently used in synthesis reactions (reactions to make certain chemicals).  Its often used chemically as an electron acceptor, a solvent for a reaction, or a medium for a reaction.

The link below makes sense in the articles cite dimethylsulfoxide as a free-radical scavenger, just meaning that it likes free electrons, and picks them up. 

I'm glad to see that this is written by seemingly credible sources.

bb

I too was wondering the efficacy of DMSO, so I did google it, here is a web page with 5 links linked to science papers.  http://www.dmso.org/subLevels/what.htm 
Title: Re: DMSO and DMSO based Solutions
Post by: phil on December 12, 2005, 08:55:03 PM
I went to the link and found reference to using DMSO to carry cortisone deeper into tissue.  I recall an earlier post wherein someone suggested this.  Has anyone used DMSO with hydrocortisone?  or verapimil?
Title: Re: Women Speak Out about Peyronies Disease
Post by: j on December 15, 2005, 10:29:10 AM
Phil, I dsagree about DMSO.  I think that one is just a lot of 3rd-hand rumors and wishful thinking.  







Post moved from "Women Speak Out"
Title: Re: Women Speak Out about Peyronies Disease
Post by: Barry on December 15, 2005, 04:09:26 PM
To whom it may concern,

Everyone is allowed to express their opinion on this forum. Some opinions are based on fact and others based on conjecture. At the risk of sounding pretentious my knowledge in both research and application of DMSO is vast. For anyone to say that DMSO plays no efficacious role in the treatment of Peyronie’s Disease is tantamount to ignorance by its very definition. I have worked personally (one on one) and on forums with countless men with the Thacker Formula for example, DMSO is the driving force behind that formula. DMSO has also proven itself as a stand-alone treatment as well. Those who would choose to disclaim my statements need only read the 1,000 posts available on this forum pertaining to the Thacker Formula and my involvement in its current developed state.

I also have available to anyone, a complete A-Z instructional explaining how to use the Thacker Formula authored by me.    

Warm Regards,
Barry    


Post moved from "Women Speak Out"
Title: Re: DMSO and DMSO based Solutions
Post by: Hawk on December 15, 2005, 07:20:34 PM
The previous 2 posts were made under "Women Speak Out" in response to a recommendation by Phil to use DMSO.

Let the discussion continue !       ;)
Title: Re: Thackers Formula Revised
Post by: Barry on December 17, 2005, 04:14:38 PM
By request I am posting a newly revised version of the Thacker Formula to this topic.


Thacker Formula-Revised…12/17/05

An Informational,

My communications with Thacker confirmed much of what was believed from the little information initially given. The discussions covered the following, Thackers use and results of his Grandfathers Formula…..Doctor Thacker, Thacker stated that Peyronies Disease starting with Doctor Thacker, who suffered from Peyronies Disease, as well as his uncles, father and himself. It seems to indicate in theory that Thackers family from his Grandfather to himself had a Genetic Pre-Disposition to this disease. Thacker indicated to me that DMSO and its quality was of the utmost importance, as expressed to him by Doctor Thacker and clarified many times. Unfortunatly, the source of Doctor Thackers DMSO is unknown. This does not negate the other two ingredients in any way and their importance to the formula. Thacker confirmed the 70%-20%-10% mixture as what was used by him. Thacker did stress that a high quality Apple Cider Vinegar be used, I told him that many men were using organic ACV and he did not agree nor disagree, but additional research indicated and confirmed that Organic ACV should be used. Castor Oil is generic in nature, so any brand will do. Thacker said that his Grandfather used the formula on men with Dupuytrens Contracture, aka (DC), he did not mention results, but it was used never the less.

Taking nothing from Thacker, it must be understood that he was for the most part a “user” of this formula, and did not in fact know much as to what the components did or why. His Grandfather mixed it for him; Doctor Thacker pre-mixed the formula, and gave it to him as needed with instructions on how to apply it.



I suggest strict self-obedience with the treatment and trust that it will work. It takes some time.
You must keep the wrap soaked during application.
The garlic odor from the application could be bathed off and a scented cream such as Aloe Vera applied to the penis after application, but the internal odor that omits through the skin pores and breath, is something you have to live with, and I can only suggest strong breath mints and wear cologne to envelop the smell. That will usually cover it. My own personal research has concluded that gently massaging the plaque after application is acceptable as long as it does not incur pain. Do this for about five-ten minutes.


THE FOLLOWING IS A DIRECT QUOTE FROM THACKER TO ME

QUOTE
“I usually followed my evening application with a hot bath and massaged the plaque forcefully but not painfully. It took about three to four months for me to start seeing results and then positive results started coming quickly. The hard nodules will suddenly start getting soft. They may break apart. Once that starts happening things improve fast. You should realize increased erection quality right off the bat. The DMSO
will smooth the muscle in the penis.”
“Once the hard nodules start getting soft or breaking up into bits. It took about six more months of application and message to finish it off. My penis then healed almost back to pre-Peyronies Disease. I would say that I am 90% where I was. I no longer have any hard pieces of plaque in my penis. I have one small indentation left where a huge piece of plaque was that did not heal all the way back. The curve will reduce slowly as plaque resolves. I started with a 50 degree curve when it was at its worse, and now, no noticeable curve”
END QUOTE


Mixing Procedure,

You MUST, wash your hands with any type of hand or body soap prior to the mixing process.
The formula CAN be premixed. How many days in advance were not discussed with Thacker but all indications lead to 3-5 days. The premixed batch must be sealed when not in use and kept at room temperature. (DO NOT refrigerate premixed batches). The formula is comprised of 70%DMSO-20%Apple Cider Vinegar-10%Castor OIL. In order to mix the formula use three separate 10cc syringes and draw the liquid up to the 1, 2, or 7 mark depending on the liquid. Then squirt each one into a small glass bowl and mix well with an eyedropper.


Application Method.

Warm the formula prior to use; this should be common to its application. Soak the mixture on a flannel sheet of cloth (NO coloring, MUST be white) or an appropriately sized strip of sterilized gauze. Wrap the cloth completely around the penis, then to hold it in place use white medical tape, rubber bands or uncolored string. Do this application once daily (the evening hours would be preferable to most), and as consistently as possible through the week. The duration in time should not be less then 1/2 hour, although 1-2 hours is favored. DO NOT refrigerate pre- mixed batches, if you do, throw that batch away. Also, if you get redness or blistering, discontinue use and apply Diaper Rash Medicine or Aloe Vera to ease the problem and correct it. Once corrected continue treatment.


CAUTION!
DMSO is a very safe solvent when purchased in a pharmaceutical grade of at least 99.96% purity.
While the bottle is open and/or the batch is being pre-mixed be very cautious and not get it into you eyes. If you do go the nearest E.R, they will know how to treat you with an eyewash.
Also, pure DMSO is not to be taken internally. The same conditions apply as to the above remedy.

DMSO is a very powerful delivery agent, meaning that it will transfer thru your skin and into your body anything on your hands, so it MUST be used under Sterile Conditions.


DMSO on line Purchase Sites,

www.webvitamin.com Natures gift
www.lifesvigor.com Natures Gift
www.herbalremedies.com Clinic Service Co.
www.kornax.com Rich’s



I am not a Doctors and do not profess to be, I am however, an avid researchers and bring this treatment to you with no promise of efficacy but, but most assuredly a sparkle of hope.
This formula is an ALTERNATIVE, non-Medicinal treatment. Years of research have been invested by me and another Peyronies Disease survivor who’s research efforts played a solid role in putting this formula together thus allowing me to put this formula in writing for all Peyronies Disease sufferers to try. Your Doctors may attempt to convince you that the use of this treatment is flippant; the ultimate decision to use this treatment is up to you. The general statement Doctors use is, “it has no basis in science”, to that I say, tell that to the many men who have had efficacious results. Also, there are NO RX contraindications to this formula and it’s not invasive. Used as directed, it is as dangerous as taking an aspirin.


Good Luck,
Barry, aka, PDFTD,
Peyronies Disease researcher,Advocate and Survivor for 12 years
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: j on December 17, 2005, 05:03:25 PM
What is the scientific basis for the belief that a mixture of DMSO, ACV and Castor Oil might selectively attack the Type III Collagen found in Peyronie's tissue?

Title: Re: DMSO and DMSO based Solutions
Post by: Barry on January 01, 2006, 01:24:41 PM
Hopeful,

Look two posts down and you will find a revised version of the Thacker formula. I will send you a private message as well just in case you miss this post.

Regards,
Barry
Title: Re: DMSO and DMSO based Solutions
Post by: Joshua on January 02, 2006, 02:11:35 PM
What is the scientific basis for the belief that a mixture of DMSO, ACV and Castor Oil might selectively attack the Type III Collagen found in Peyronie's tissue?

I think this is very good question J. I am interested in dmso but I need to ask myself why would this help? I do think dmso might reduce some of the inflamation in the area but I agree it could not possibly selectively attack type III collagen. So it could be helpful but just not a cure. there is some great info on dmso at dmso.org including studies.
Title: Re: Joshua : ACV+Fish/Evening oil/vip cream/Dmso = Peyronies Disease cure?
Post by: learn4life on January 06, 2006, 01:32:22 PM
What is the scientific basis for the belief that a mixture of DMSO, ACV and Castor Oil might selectively attack the Type III Collagen found in Peyronie's tissue?

I think this is very good question J. I am interested in dmso but I need to ask myself why would this help? I do think dmso might reduce some of the inflamation in the area but I agree it could not possibly selectively attack type III collagen. So it could be helpful but just not a cure. there is some great info on dmso at dmso.org including studies.

Dmso plus ingriedients to produce Pro-E1+Nitric Oxide , deeply into the penile colagen scars/nerves/Arteries/Veins might actually help cure Peyronies Disease?
It could dissolve it gradually.

I wish to try the above as Iam experiencing good results with daily
Fish oil/vip cream/ACV massage. In my case  it has tooking over a year to dissolve some of the colagen scars with small hiccups along the way.

I have ordered from DMSO from US but they cant ship it out to the UK so if anyone has any UK links to where I can purchase DMSO, please let me know. It would be much appreciated.

I seriously think this treatment could finish off dissolving the remaining deep Peyronies Disease colagen scars.

Cheers !




Title: Re: DMSO and DMSO based Solutions
Post by: totheleft on January 09, 2006, 08:15:01 PM
hello all, hope everyone had a good holiday...

I have been using Thackers formula, for the past three weeks plus I started using primrose oil massage on my plaque after I have taken off the thackers dressing for the past week. Can anyone tell me , how long after using the thackers formula that they started seeing a reduction in the curve. On top of all this I am also using daily Gamma Vit E, Vitalzym, and acetl L carnitine /lipoic acid combo. It has been 11 months since my first symptoms and still no results except for the reduction in pain. By the way also used topical verapamil for six months which only resulted with less money in my pocket.........................my best to evryone ........totheleft
Title: Help offered on DMSO & Thacker QuestionsDMSO and Thacker
Post by: Rzz on April 20, 2006, 01:05:21 AM
Hello. My forum name is Rzz. Over the last 2 years I've done tons and tons of research on DMSO itself and its use in treating Peyronies Disease, including "Thacker's Formula." For anybody who is new to this area and even for those who have read about it before and are looking at it again, I'd be more than happy to answer any questions you may have regarding the subject. If I do not have the answer, I more than likely can find it or know some top experts who I can call to find it. Remember, Peyronies Disease is still a mystery; so of course there may be some questions about DMSO and Peyronies Disease for which there is no answer. For some unknown reason the use of DMSO in treating Peyronies Disease helps some, but doesn't help others. Also, for those who do see improvemnt, the degree of improvement varies. One thing is for certain, one will never see improvement with DMSO unless it is used correctly and with care. If you have any questions, please don't hesitate to ask. If I don't get back to you right away, don't be discouraged. I will respond as soon as possible. Ussually no more than 4-5 days. Thanks,       Rzz
Title: Re: DMSO / Thacker Question
Post by: Rzz on April 29, 2006, 05:25:16 PM
I received this in my private messages and will try to answer the best I can.

*** "Hello, I am sort of new to this forum and don't have any knowledge about this formula or DMSO? I currently have an Hourglass shape at the base and have been prescribed Topical TV which was very expensive out of pocket. I thought I would look into other options as well, when I ran across your last post on this. Any info would be greatly appreciated." ***

The first thing I strongly suggest you do is read the entire thread of "Powerful Home Remedy." Yes it is a long thread, but you need not read it all in one sitting." The information in this thread is invaluable in not only understanding "Thacker's Formula," but also the use of DMSO in treating Peyronies Disease.

With the exception of surgery, unfortunetly and regardless of the type of treatment, the hourglass shape is the most difficult to see postive results in. This does not mean postive results can not be had, it just appears it is the least responsive to treatment. This includes the "Thacker Formula." One must understand, if postive results are going to be seen with any treatment, it is going to take time. Not days or weeks, but months and months. Some have not seen results until more than a year has passed. Again, I strongly suggest you read the entire Thacker's Formula thread and if you have any questions please do not hesitate to ask. I hope this helped.               Rzz
Title: Answer to a Question on DMSO
Post by: Rzz on April 29, 2006, 06:16:21 PM
I received this question and another question in my private messages. the 2nd question can be seen in the post before this one. Since they were sent to me in my private box, I will not attach thier names. I will try to answer the best I can.
___________________________________________________________________
Hi Rzz,

I'm interested to know if DMSO can help my condition.  I acquired peyronie's when i was a teenager learning to masturbate in an unorthodox way.  I didn't know that I had peyronie's until now, eleven years later.  I have a twenty degree left curve, which doesn't bother me so much.  What bothers me more is the very tight hourglass shape my flaccid penis takes on at times, for some reason more when i'm cold and sitting on the toilet.  Only when it tightens into the hourglass am I really able to feel scarring.  Otherwise it just seems to disappear when the hourglass fills out.  It's very strange, and has caused me to go into pretty deep depression at times.  I'm very interested in learning more about dmso, because I think it's my only hope of improving my stable peyronie's.  Thus far I've been very hesitant to try it.
___________________________________________________________________

First there is something I'm not sure I understand about your question. You say you aquired Peyronies Disease by masturbating in an unorthadox way and you didn't know you had Peyronies Disease until now, 11 years later. Are you saying you've had Peyronies Disease for 11 years and did not know it until now? What makes you think you've had it for 11 years? Do you mean you've had the symptoms of Peyronies Disease for 11 years and you've just now been officially diagnosed by a doctor as having Peyronies Disease?

Two things and I stated these in the post just before this one. For me to explain all about DMSO and the treatment of Peyronies Disease with DMSO would take many, many pages. So I strongly suggest you read the entire thread "Powerful Home Remedy." After you've read it or while you're reading it, if you don't understand something, please ask and I will happily answer.

You mention you've been hesitant to try Thackers Formula. I assume this is for safety reasons. That is understandable. I'm not tryig to convince you to try it or not try it. That decision is yours, but as far as the safety issue goes I will say this. I've done tons and tons of research on DMSO and Thackers Formula. In my opinion and although you may or may not achieve positive results, it is very safe in the treatment of Peyronies Disease as long as you follow the instructions. The worst results I've seen reported is a slight redness and burning and these went away after 2-3 days. In addition, these side effects were not caused by the DMSO as most people think, but instead they were caused by the apple cider vinegar used in the formula.

If you read the post I wrote before this one, you will see that I stated the "Hourglass Affect" is one of the least responsive to any type of treatment, including Thacker's Formula. This does not mean postive results absolutely can not be had. You did not state your condition when erect. Is the hourglass affect worse when erect? Are you able to have intercourse? These questions are helpful in giving you a full answer to your question. Again please read the post I wrote right before this one.

Depression is in my opinion the worst effect of Peyronies Disease. Doctors are finally now starting to realize this. What I can say to you is that there is hope. This disease is FINALLY getting some serious attention by the medical community. We still have a long way to go, but it is moving in a positive direction. Hang in there and one piece of advice. Do something about your Peyronies Disease. What I mean is attack it. Don't just sit around and wait for something to happen. Try something. Be very careful and do your research, but try something.

Good luck and hang in there friend,       Rzz
Title: Re: ToTheLeft - Thacker's
Post by: hopeful on June 19, 2006, 08:24:22 AM
Hello To The Left- I am thinking of trying this- how did this work for you-?-any improvement- how long have yo9u had Peyronies Disease- and how bad?

Hopeful




hello all, hope everyone had a good holiday...

I have been using Thackers formula, for the past three weeks plus I started using primrose oil massage on my plaque after I have taken off the thackers dressing for the past week. Can anyone tell me , how long after using the thackers formula that they started seeing a reduction in the curve. On top of all this I am also using daily Gamma Vit E, Vitalzym, and acetl L carnitine /lipoic acid combo. It has been 11 months since my first symptoms and still no results except for the reduction in pain. By the way also used topical verapamil for six months which only resulted with less money in my pocket.........................my best to evryone ........totheleft
Title: Re: DMSO and DMSO based Solutions
Post by: ComeBacKid on June 19, 2006, 12:37:45 PM
Yet another person who used TV with no results... what a surprise.

ComeBackid
Title: Explanation of this Topic
Post by: Hawk on August 01, 2006, 10:09:03 PM
These posts were originally made on an old forum and later deleted from that forum to make room on their server.  Joshua, a Co-founder of the PDS retrieved these posts.

What follows is a discussion of a DMSO home remedy mixture referred to as the "Thacker Formula".  No studies or even organized survey have ever been done on this formula. Studies on DMSO for any human use are very limited.  This information is here for the interest of those that were familiar with the now defunct "old BTC" forum, its members, posts, and those with a general interest in this formula.   

The old discussion on this formula were in 2 topics.  They are both listed below.  This topic should be read starting at the bottom and reading up to the top where the newest posts are archived.

This topic is for reading only.  No posting or discussion is permitted here.  There is a DMSO topic on the main forum page for discussion.
Title: Thacker Formula - easier mixing.....
Post by: Rico on August 10, 2006, 06:06:17 PM
I would like to talk to anyone using this formula, dmso/avc/Castor oil.

I started it last night, I spent about 25 dollars on all my supplies. This should last me about a month.

I bought 99.9% dmso(I really didn't notice a smell or burning) and organic apple cider vinegar and Castor oil.

My plaque is on the top of penis shaft, 1/2 inch up from base, dead center. I live alone also so I haven't done a wrap. I also broke down the formula to make it easy to mix. I bought two eye droppers also, the formula is 70%dmso and 20% acv and 10% Castor oil....this is for large batch one tablespoon dmso, one tsp avc and 1/2 tsp Castor oil, for a small batch, you can use 1 1/2 tsp dmso, 1/2 tsp avc and 1/4 tsp Castor oil, I sit my swallow clean glass in a pan of hot water on the stove, get it nice and warm(you don't cook the mix, just have it warm, I find that just heating the glass works) then I take out glass, wash my hands with soap and water and then add my dmso, apple cider vinegar and then Castor oil and mix it up with the eye dropper, I sit on a towel and watch tv and apply the cream, it I massage it in with the side of the eye dropper, I did this last night for about one hour. When it becomes absorb, I put more on till gone, I then take a bath or hot shower and massage the area, when done I cover the whole thing with arnica oil Caledonia oil(sp), I bought this at the store I found.

I stayed away from doing this for the last couple of months(have had peyronies now for four months), because of the bad experience I had with dmso about 25 years ago, nasty, I can still taste it. I bought it black market then for a sport injury, it was cheap grade and made my skin blister. This 99.9, I notice no bad taste or smell. I going to take epsom salt baths and massage the area longer when I can on the weekends and more treatment also. I have broke of scar tissue before in my body, deep tissue massage, I don't want to do it as rough(cause more damage), but I do believe it is good to gently massage the area to keep it supple.

I'm getting ready to start VED when the new Soma Correct comes out, and I'm trying to condition my plaque, softer ect....

I posted this for anyone interested in a easy way of breaking down the formula. If you plaque is on the side of penis you can add a little more Castor oil to give it more body for a easier massage application.

I have enough product for a month, then will see what I think, anyone else out there trying this, like to here from you, or anyones thoughts are welcome....Take care and God Bless...

Rico
Title: Re: DMSO and DMSO based Solutions
Post by: Tim468 on August 10, 2006, 10:33:05 PM
Good work Rico - I hope it helps.

Tim
Title: Re: DMSO and DMSO based Solutions
Post by: Rico on August 10, 2006, 11:21:54 PM
Tim,

Thanks. Please google Iontophoresis rehab/management

I found this interesting. I started the thacker formula because I have a culinary background and I believe in vinergar, I have seen what it can do to fish and many other things, eggs ect...keeping the flesh in tacked while killing everything else, bacteria ect...apple cider caught my eye because it is 6%(organic) acetic acid. I believe the dmso is the driver like Iontophoresis and the cator oil gives it a base to stay on the area being treated and also keeps the skin soft from blistering and the acetic acid in the apple cider breaks up the scar tissue.

I started to google acetic acid and found this site, it says with iontophoresis to break up calcified tissue, you should use acetic acid 2-5 %.

I just finished my second treatment tonight. My cost for a month I think will be under 30 dollars.

It also talked about sski, which I have looked at, but felt more comfortable with the apple cider(acetic acid), the dmso 99.9% I have found no real off ordor or blistering.

If I could get my dick in a jar, I would pickle it:). A apple a day, will keep the pecker checker away:).....

Rico
Title: Re: DMSO and DMSO based Solutions
Post by: ComeBacKid on August 10, 2006, 11:23:51 PM
Rico,

Interesting, I had alwasy wondered if there was something out there that could be used instead of verapamil or decadron with ionotpohoresis, to drive it into the plaque and dissolve it. 

ComeBackid
Title: Re: DMSO and DMSO based Solutions
Post by: myrddin on August 11, 2006, 09:30:50 AM
I'm considering trying DMSO, but has anyone tried using the DMSO creams or gels that are available?  For instance the selection at the bottom of the page here (http://www.myvitanet.com/dmso.html?gclid=CMeTn7Ld14YCFUWFFQod_GdG7A)? Also note I know nothing about this site and am not trying to promote it or anything, I just saw it from a Google search and it seemed to be an easier and more pleasant way to administer than mixing up a batch of Thacker's.

If any of you have experience with these let me know.
Title: Re: DMSO and DMSO based Solutions
Post by: Rico on August 11, 2006, 09:23:21 PM
I'm no expert, but what I read you want the 99.9% dmso. Thacker also has the apple cider vinegar. Now I have only started this treatment, three days now, so I can't comment on how it is working, just what I have read. Be careful with dmso, it is very powerful, don't have around kids ect...don't get in your eyes ect...Please read up on this before you start, if you choose to...God Bless you and I will pray for you..remember the Sun Also Rises:)..

Rico
Title: Thackers Formula
Post by: ComeBacKid on September 15, 2006, 02:05:30 PM
I've purchased the DMSO, apple cider vinegar, and finally the castor oil which is apparently for upset stomachs or something of that nature.  I got gauze and some medical tape to tape the gauze, now I just was looking for exact instructions on how to mix it.  Can one use the same needle and draw out the quantities and put them in a  bowl?  Then simple soak the gauze for ten minutes and take it out and wrap around the penis?  How much in mL of each liquid should be placed in the bowl for mixing, and how should one mix exactly?  Anyone using this with some comments and more specific instructions feel free to post them or PM me.

ComeBackid
Title: Why Do This?
Post by: Liam on September 15, 2006, 06:12:27 PM
How in the world could any of these ingredients (chemicals) help Peyronies Disease?  What is the mechanism?   The whole idea sounds like a cruel joke, mix salad dressing (oil and vinegar) with an industrial solvent.  Then tape it to your penis.

I am as bad as anyone about trying potential "fixes" for Peyronies Disease.  But, guys......

Now, if anyone can give me a plausible, scientific reason this would work, I'll be happy to have crow fricassee for dinner.
Title: Re: DMSO and DMSO based Solutions
Post by: mark501 on September 15, 2006, 06:57:05 PM
Liam, Many thanks for your post on DMSO.  The following is on the label of  one of the most popular DMSO gel preparations sold on the internet at 99.9% pure. "Caution; may cause skin irritation. Avoid contact with eyes, skin & clothing. In case of eye contact immediately flush eyes with water. Call a physician.  Sold as a solvent only. This product is intented for use as a solvent only. The choice of the process  used in the various applications is the sole responsibility of the user. It is unlawful to represent in any way that this product is useful or safe to use for medicinal purposes. Keep out of the reach of children. This product is sold on many websites right along with vitamins and beauty creams ,the implication being that this product is in the general category of  food supplements & cosmetics. How much more explicit does a label warning have to be? Think! 
Title: Re: DMSO and DMSO based Solutions
Post by: Tim468 on September 15, 2006, 09:54:55 PM
DMSO has some data collected over the years that shows that it is generally safe, and that it can be of help in relieving pain in arthritis. Most other claims are not well studied, except for cystitis pain; DMSO can be injected into the bladder to help with that.

MSM is a breakdown product of DMSO, but is not as well studied. it may have many of the same effects, though these effects are generally assumed, but not proven. A good review of this matter is found at:

http://www.arthritis.org/resources/arthritistoday/1999_archives/1999_11_12explorations.asp

All of the reviews I read pointed out that the DMSO available in health food stores is NOT medical grade DMSO - even the 99% pure DMSO, which is still industrial and not medical grade. I believe this has to do with manufacturing standards and the potential for impurities to be in the  solution.

http://www.quackwatch.org/01QuackeryRelatedTopics/OTA/ota05.html

This has a good discussion of this matter.

I think DMSO is of unproven benefit for Peyronies Disease, though it has potential. I am VERY suspicious of a formula that is secret and which refuses to show any data (the mysterious Thacker formula). All the Thacker thread claims strike me as bogus, in that the posters are not open as to who they are, they do not apear willing to share their "secrets" - and other signs of fakery I have seen before. This is just my opinion.

Tim

ps - I have worked a lot with DMSO, and it gets across cell membranes fast. A drop on the finger will be tasted in the mouth in about 15 seconds (absorbtion and blood flow time). It can carry small molecules across tissue planes which makes me think it could be used to move drugs into the tunica easily (ie verapamil or soulbilized Pentox - get it right to the problem.

Tim
Title: DMSO and Greyhounds
Post by: Liam on September 15, 2006, 10:06:00 PM
I use to race greyhounds.  I now rescue them.  The trainer sprayed them down with DMSO after a race to prevent sore muscles.  It seemed to work.

I remember the first time I heard of DMSO.  It was from a man who swore WD40 helped his arthritis.  Just spray it on the joint and it goes through the skin and lubricates the joint.  Now that doesn't speak to the effectiveness of DMSO.  It does show personal accounts of effectiveness should be taken with a grain of (Epsom) salt  ;)
Title: Thackers
Post by: ComeBacKid on September 16, 2006, 08:55:56 AM
It was Barry who original told me all about thackers, he told me it will work and has talked to a handfull of people who used it and saw results.  Barry is the one who originally talked to this infamous "thacker," guy.  I like most on here am a skeptic but willing to give this a try for now.

Rico,

So you simply add in the measured quantities as you stated into a bowl and mix them all up(I don't have an eye dropper), then let the guaze soak for 5 minutes or so?  Then wrap onto the penis and tape it on?

ComeBackid
Title: Thacker formula - some logic?
Post by: percival on September 16, 2006, 12:20:08 PM
Liam
I too have some doubts about the Thacker formula, but there is a bit of logic in it:
I should think that the vinegar is there with the intention of dissolving the calcium out of the plaque. Can't say why cider vinegar is used, 8% acetic acid would probably work as well, unless there are some minor components present in cider which are important.
The inclusion of castor oil sounds like a treatment they use to soften leather. During the tanning process, the natural oils get extracted and the leather becomes stiff. This is rectified by 'fat-liquoring' in which a natural oil such as castor oil is emulsified (often sulphated castor oil is used) in water and the leather is churned in it. This results in supple leather. Whale oil used to be used and it produced very fine leathers for gloves. High quality gloving leather has to have good stretchability to 'fit like a glove' so I think that this may be the idea behind the Thacker formula - using a natural oil to soften the leathery plaque.
As for DMSO - it is well known for permeating the skin and presumably will carry the vinegar and castor to the plaque.

Maybe it would be worth carrying out an experiment with say, a section of pig's ear to see if the Thacker formula softened it.

How in the world could any of these ingredients (chemicals) help Peyronies Disease?  What is the mechanism?   The whole idea sounds like a cruel joke, mix salad dressing (oil and vinegar) with an industrial solvent.  Then tape it to your penis.

I am as bad as anyone about trying potential "fixes" for Peyronies Disease.  But, guys......

Now, if anyone can give me a plausible, scientific reason this would work, I'll be happy to have crow fricassee for dinner
[/color]

Crow sounds leathery!

Percival
Title: DMSO & Pig's Ear
Post by: Liam on September 17, 2006, 10:07:15 AM
I shall summarize my thoughts of the application of DMSO, Cider vinegar and Castor oil:

to a Pig's ear - good

to a penis     - bad

On the gulf coast we use Adolph's meat tenderizer for jelly fish stings.  So, it has a medical purpose.  "Meat" tenderizer (wink, wink, nudge, nudge)....hmmmm.  Maybe a good addition to Thackers formula.  After all it tenderizes meat.  And, it will draw the inflammation out like it draws the poison from a jelly fish sting.

Sometimes an analogy may be misleading.  Sometimes not.  Thats why scientific investigation and then scientific testing is done.

Liam
Title: Evidence tough to come by
Post by: ComeBacKid on September 17, 2006, 11:24:27 AM
I like Liam often times found myself thinking, is this someones idea of a cruel joke? 

I don't believe so, Barry has told me that he talked to thacker himself and has talked to many people that this has worked for.  I first found out about this thackers on the old BTC jungle forum.  I believe barry and take him at his word.  I did a little research and it does show what Rico has been telling us that DMSO can dissolve or soften old scar tissue.  I've often wondered as Tim has stated, could DMSO carry verapamil or decadron into the plaque or scar tissue itself? 

I wanted to make two more points, one is I've been in touch with soxfan who is seeing results from the VED and using thackers, which he claims has helped to soften his plaque, besides this I was in touch with a man named Nick Foxx off the old BTC, he is registered here but does not post, he used MSM pills for awhile and saw good results and straightening.

Any scientific evidence on this stuff...no of course not, any scientific evidence on the VED's... I have yet to see it, but we now have about 5 people reporting results.  For most of this stuff there is no scientific evidence, thats just the way it is, I think Rico has made enough of a tie with DMSO's ability to dissolve scar tissue and go deep through cell membrames to show it could work, this is all I need to try it.  I don't mind the skeptics and constructive thinking and exchanging ideas, but lets all try to stay away from being CRITICS, we are all in this together.

ComeBackid
Title: Critics Vs. Skeptics and DMSO
Post by: Hawk on September 17, 2006, 01:56:49 PM
I don't mind the skeptics and constructive thinking and exchanging ideas, but lets all try to stay away from being CRITICS, we are all in this together.

Critic -1. "on who forms and expresses judgements based on the merits of a matter" 3."one who makes harsh carping judgements"

I am not sure I understand the the difference between the primary definition of a critic and a skeptic, especially when we encourage "critical thinking".  I think we need both.  The attack of a concept with evidence is always good.  The attack on an individual sidetracks the argument and has no place.  Again, in this case I use the term argument to mean "a course of reasoning aimed at demonstrating truth".  We have had no personal attacks and certainly no "harsh carping judgements".

Now, on to my critical, skeptical view of DMSO.  Which I have used extensively in veterinary applications on birds of prey.

There is no doubt that DMSO will transport substances within the limit of specific molecular weight into tissue.  It is an easily reproduced demonstration.  There is no doubt in my mind that people have used DMSO and improved.  There is doubt in my mind whether DMSO played a role, or if vinegar played a role, the combination, or neither. 

In order to work, DMSO would have to do the following.  Transport a agent that reduces scar tissue past a network of capillaries that would uptake the substances and yet not penetrate beyond the target.  I think we have little other except anecdotal accounts that it can reduce scar tissue or give the targeted delivery needed.

Alternatively, DMSO could reduce inflammation in acute Peyronies Disease.  Or stimulate blood flow that actually helps healing.  I would be interested in how it help heal 2 cuts on a hand, one treated and one not treated.

Many men with Peyronies Disease never have calcified plaque.  I seem to see a line of thought among some that market products and some of us hoping for a really good treatment that goes something like: "A certain drug or concoction really is known to reduce the plaque or scar tissue in the underlying tissue."  Yet no one ever seems to claim these products can eradicate even the tiniest dermal scar much less a keloid that we can easily apply products directly to, then watch, and measure the results.  Sophisticated research has been undertaken to reduce scaring in burn victims, keloids, and surgical adhesions.  It is clear that many things help, but very few of these are included in the list that we use.  I think it is a stretch (I should be PUNished) to think these things only work where we can't see, but would not effect other scar tissue open for examination.
Title: Re: DMSO and DMSO based Solutions
Post by: Tim468 on September 17, 2006, 02:01:34 PM
I think it counts for a great deal to have people who we trust to be honest (like Barry) to say "I used it and I got better". But that is not, as you have mentioned ComeBackid, the scientific method. We are not doing science here, either. we are experimenting, but it is to see if we can make empirical connections (IOW, connections not proven but implid by a connection )(ie not just cause and effect).

In fact, a bunch of positive reports is still not science. What if the guys who responded to ionto of verapamil happened to be posting here and said - "this really worked for me!" Well, it would be inspiring - and we would try it.

The action of DMSO to enter into cells is well known. The action of it "breaking up scar" is not known, and not even close to being proven. The logic behind acidic environments helping, or oil helping is all conjectural.

Yet, someone thought it up and it seems to have helped someone. So... the question is it more than would be healed by a placebo?

Well, I would take a placebo if I thought it would work. God knows I have taken a lot of crap.

So I will be interested to see what helps or does not.

Tim
Title: Look this isn't Scientific....
Post by: ComeBacKid on September 17, 2006, 02:11:53 PM
I just want to say to everyone who can point out there is no scientific evidence this can work or to be shown it will work.... I know this.  But for most of the treatments on this forum we have ABSOLUTELY no scientific evidence.  Look to the VED's for example, no studies at all(supposedly there is one out there but not public), and yet I've talked to 5 people who have seen results from the VED. 

Barry has stated to me that MANY people have seen results from thackers formula, I take him at his word and believe him, and yes this is NOT scientific, since the medical community is not doing much in the way of studies we have to try our own.  From what I've read I have no reason to believe DMSO is dangerous at all what so ever, obviously try everything at your own risk.  My theory is to try every single thing possible to throw at this crap.  I think it is good to be a skeptic and throw and have critical thinkign I do this myself, I was more referring to the jokes, perhaps my definition of a critic and skeptic is confused, critic is the wrong word for what I wanted to say, I meant more in the way of hecklers. 

I trust MOST of the people on this forum, for soxfan to tell me thackers softened his plaque and Barry to tell me it has worked on many people I'll take that as the closest thing to scientific we will get on this topic. 
Title: Surrounding Cells & Critical Thinking
Post by: Liam on September 17, 2006, 05:28:57 PM

Why would Thacker's Formula only "attack" plaque and not damage other surrounding cells?  Will long term use completely destroy the functionality of you penis?  If you were betting on this, what would be the odds?  Is it worth the risk?

BTW, I apologize if anyone thinks I'm attacking a person or persons.  I am challenging an idea in an effort to encourage critical thinking.  My tone was and is one I would use with my brothers (as y'all are).

I was taking DHEA until Hawk challenge me to critical thinking.  I am off of it now.  Thank you to Hawk.

Liam


Thacker's spellchecks as Thwacker's  ......hmmmmm.......
Title: Old Wise Man Where are you?
Post by: ComeBacKid on September 17, 2006, 06:12:46 PM
I think at this point we seem to have hit a stalemate, Rico you have made some excellent points, Liam and Hawk have challenged the idea of how and why thackers will work, nothing wrong with this either. 

At this point, I think it would be appropriate for Barry to enter the discussion and tell us his stories and how many people he communicated with that said thackers helped them, I think we can all trust Barry(at least I can) as he has been a peyronies advocate for years and a friend of the forum/administrator.  Old Wise man where are you?  Perhaps SoxFan telling us his story might help to convince some of the people, as far as a study we won't get one, won't happen. 

Safety should be the prime concern for all treatments, besides if they will work or not.  I would also like to see more information on safety in regards to DMSO, but for now I think I willl continue using it.

ComeBackid
Title: Re:ComeBackid
Post by: Hawk on September 17, 2006, 08:17:45 PM
ComeBackid,

No one is questioning Barry, certainly not me.  But whether Barry relates it first hand or we see a CBS special report on the cases, or read the Thacker threads (which I have read every word of) it does not answer the questions about dermal scars, evidence of DMSO fighting inflammation, non-calcified plaque, or the accuracy of what others reported to Barry.  Believe me, I wish everyone on the forum would try it and report back.  If more than 15% resolved significantly better I would probably give it a try.

I just think anyone using it might as well find another spot of scar tissue on the body, or an active cut or two that they can observe, and do some real experimenting while they are at. Then if someone gets results we could have an active ongoing probing exchange directly with that person.  It will still just be anecdotal evidence, but more interesting.  I clearly expect that if 10 people try it one or two will show some improvement worth mentioning.  That would be expected.  If 3 or 4 show such improvement then is getting interesting.  If 3 or 4 get improvement out of 30 then that is zero improvement because that is on par with "spontaneous improvement.
Title: Thacker - apply neat or dilute?
Post by: percival on September 23, 2006, 05:26:37 PM
I have read so much about the Thacker mixture, and I understand that the basic formula is:

Thacker formula, I mix it using 7 teaspoons of 99.9% pure dmso+2 teaspoons of apple cider vinegar+1 teaspoon of castor oil.

However, is the idea to apply this neat or is it supposed to be diluted in water first - if so to what extent?
 
I have read of Rico's trials and he seems to have burnt his 'unit' (a wonderful name for it). As I do not want to duplicate this result - I can imagine having to explain it to the Accident and Emergency department - I would appreciate advice on how to apply the Thacker mixture.
Regards,
Percival
Title: Re:Percival
Post by: Hawk on September 23, 2006, 07:00:16 PM
Percival,

I will echo that until you are committed enough to read every word of this thread and the Thacker Formula archive, you should not attempt use of this formula.

While it will not carry bacteria through your skin, it will rapidly transport anything with a molecular weight of less than 1000.  Anything that touches the DMSO, including body parts, cloth, or containers, need to be free of impurities. Wash and then rinse thoroughly to remove soap or fragrances.  It is not unusual to get a taste in your mouth within seconds of getting DMSO on your hands.  It commonly gives an odor to your breath indicating it goes directly into your blood stream and is respirated through the capillaries in the lungs.
Title: Dmso reaction....
Post by: Rico on September 29, 2006, 02:39:31 PM
Dear forum members and guest...

I have been using the thacker formula for about six weeks now....I had to take a week off in the beginning when I had some skin irritation...

I notice when I would do it in the beginning my unit would always react, maybe like it was a little shock from the mixture...using the thacker(dmso/acv/castor oil) and I was using more, I put mine on with a eye dropper right on the plaque, like a slow drip, I do this for one to two hours, the most I use is a tablespoon of mixture.... well after four or five days of doing this, my erections start to become non existence and it is hard to stimulate myself....

Now I have been watching this, if I take one or two days off, they pop back....so there is something going on with the thacker....my plaque fills softer and was on the top of septum in one piece, now the middle of it is separated in two pieces, I don't know if it spilt when I started to use VED....I had been conditioning it for six weeks with the thacker to help stretch it....

I took off last night and did a Epsom salt bath instead of thacker, just cause I was concern of my unit not responding(I have been under stress also), but even though I had been under stress, I had notice this before with dmso after about a week....well sure enough I woke up with good wood this morning...so I'm going to go back on the thacker tonight....I think this is positive to me....especially the plaque getting thinner on top of the septum...

I move to the b cylinder on Sunday...my hour glass hasn't improve at all and it is my real problem, this is causing my lost of length, yes lost of length....I believe when you pull it intogether this shrinks your unit...so gain of girth equals legnth....

Anyway any one out there soaking there unit in pickle juice, speak up.....

p.s. I just wanted to add  that my unit became use to the thacker, it no longer gets a rash...I put msm cream on it when not using the thacker, it is soothing to the skin...I also use several other oils..arinca and caldenula oil...

Rico
Title: Re: DMSO and DMSO based Solutions
Post by: ComeBacKid on September 30, 2006, 03:14:00 AM
Rico,

I tried the thackers formula once for about two hours, I did a wrap, I did not have any garlic breath or any side effects, no skin irritation or pain, I discontinued use because I'm not totally sure its safe, and I'm working with other drugs and the VEd, that DMSO may carry into the blood stream and have a weird reaction with the other drugs I'm on. 

Title: Thackers success stories?
Post by: ComeBacKid on October 04, 2006, 03:48:20 PM
Has anyone on this forum used thackers formula and seen an improvment of any kind in their peyronies disease?  I have yet to hear from one person on this forum thats reported a success.  I have heard from Barry of success stories however.

Title: DMSO and Scleroderma
Post by: percival on October 07, 2006, 11:09:28 AM
There are publications which show that DMSO is effective on the scleroderma type of scar tissue:
http://www.dmso.org/articles/scleroderma/sclero3.htm

and:

Collagen and Scleroderma

Scleroderma is a rare, disabling, and sometimes fatal disease, resulting form an abnormal buildup of collagen in the body. The body swells, the skin--particularly on hands and face--becomes dense and leathery, and calcium deposits in joints cause difficulty of movement. Fatigue and difficulty in breathing may ensue. Amputation of affected digits may be necessary. The cause of scleroderma is unknown, and, until DMSO arrived, there was no known effective treatment.

Arthur Scherbel, MD, of the department of rheumatic diseases and pathology at the Cleveland Clinic Foundation, conducted a study using DMSO with 42 scleroderma patients who had already exhausted all other possible therapies without relief. Dr. Scherbel and his coworkers concluded 26 of the 42 showed good or excellent improvement. Histotoxic changes were observed together with healing of ischemic ulcers on fingertips, relief from pain and stiffness, and an increase in strength. The investigators noted, "It should be emphasized that these have never been observed with any other mode of therapy."10 Researchers in other studies have since come to similar conclusions.11


Percival
Title: Re: Rico - DMSO
Post by: hopeful on February 23, 2007, 05:24:15 AM
Rico.. Has anything worked..   DMSO looks like it could have some positive effects,

HOPEFUL..

Rico,

I tried the thackers formula once for about two hours, I did a wrap, I did not have any garlic breath or any side effects, no skin irritation or pain, I discontinued use because I'm not totally sure its safe, and I'm working with other drugs and the VEd, that DMSO may carry into the blood stream and have a weird reaction with the other drugs I'm on. 


Title: Re: Percival - DMSO?????
Post by: hopeful on February 26, 2007, 08:46:27 AM
Percival

Have you tried the DMSO??-If so what did you do?-Any progress???
Hopeful


Title: Re: DMSO and DMSO based Solutions
Post by: Rzz on February 26, 2007, 03:48:58 PM
Hopeful,

I'm not sure I'm reading your post correctly. It seems as if you may be saying you are mixing other drugs with DMSO and using that. If this is what you are doing, I STRONGLY urge you to STOP. One of the major factors of pharmaceuticals is the way they are introduced to the system.   

The formula one sees on this forum does not have drugs. The formula consist of castor oil, vinegar and DMSO. The Castor Oil works as a base, the vinegar works as an enzyme and the DMSO works as a carrier. None are harmful to the system.

The reason you did not get any burning sensation could be two-fold.
1) Although at first most do get a a burning sensation, not all do. Most people believe the burning sensation is caused by the DMSO, but it is not. It is caused by the vinegar working as an ennzyme. When the burning sensation occurrs, the person should stop the treatment until the redness is completly gone, then try again. If the burning continues, you may have to decrease the amount of vinegar being used. 
2) You may not have had a burning sensation because has you stated in your post, you only applied the formula for 2 hours. That is certainly why your breath or body did not give off an odor. It takes longer than 2 hours of application.

I'm not encouraging you or anyone else for that matter to try the formula. I'm just passing on what knowledge I've gained from the many, many hours I researched this topic. Good luck to you friend.
Title: Re: Rzz
Post by: ComeBacKid on February 27, 2007, 05:13:26 AM
I think hopeful was quoting me when I was posting to Rico.  He then posed a question about dmso to rico.   

Rzz,  Have you tried thackers ?  Any luck with it if so?  Soxfan has told me hes seen results from it, perhaps he could add his experience here.  When I brought up DMSO and thackers to my urologist, he basically scoffed at me and made a joke of it.

ComeBackid
Title: Re: Rzz
Post by: soxfan on February 27, 2007, 07:23:52 PM
I think hopeful was quoting me when I was posting to Rico.  He then posed a question about dmso to rico.   

Rzz,  Have you tried thackers ?  Any luck with it if so?  Soxfan has told me hes seen results from it, perhaps he could add his experience here.  When I brought up DMSO and thackers to my urologist, he basically scoffed at me and made a joke of it.

ComeBackid

ComeBackid/All,

I can state with 100% certainty that the Thacker formula does indeed help to soften plaque/scar tissue. You do have to use it consistently, I have done so for almost a year and I also use the ved( osbon esteem model) and the p.a.v cocktail. I have regained almost all of my lost length and I am sure that with continued treatment I will completely resolve my peyronies.

PS: Let the doctors continue to SCOFF at the ved and Thacker formula. Sadly. most md's can't get beyond the notion of drugging/operating to solve all medical conditions.

Cheers.
Title: What we and docs do
Post by: Tim468 on February 27, 2007, 07:56:38 PM
>>PS: Let the doctors continue to SCOFF at the ved and Thacker formula. Sadly. most md's can't get beyond the notion of drugging/operating to solve all medical conditions.<<

When you say this, but also admit that you are using the pentox, arginine, viagra combination AND the VED AND Thacker's formula, would that not be also considered "drugging?".

If I also had a knife, and knew how to wield it, I would add that to my arsenal of tools.

In the end, doctors are people who have tools and try to use them. It is a fact that not many of the tools work that well, or we would all be using the same tools. We do what we know. What is sad is how little doctors know about something they should know a LOT about.

Tim
Title: Re: Tim - DMSO - Doctors
Post by: Hawk on February 27, 2007, 09:17:50 PM
Tim,

This should probably go under Urologists and other Doctors but you know, I would be happy to hear a doctor say, "I just don't know because unfortunately we have no data to support or refute the efficacy of such a treatment.  What kills me, is that because they do not know if a thing works the vast majority scoff.  Often they flatly say, "there is nothing to it", which is what a scoff says anyway.  This implies that they know all things and if they have no knowledge of it just cannot be.  I agree that we need objective evidence but what kills me is that many of the treatments they promote have little such evidence or even some evidence of harm.  Somehow that is OK.  Who can resolve such a contradiction?

My cancer surgeon is world renown.  He developed the laparoscopic prostatectomy technique in France and was recruited to Memorial Slone-Kettering in Manhatten.  Every urological surgeon in the world knows this man's name. I love this guy because during our 90 minute conversation which I finally ended,  I asked him if there was anything I could do nutritionally to increase my chance of beating my prostate cancer.  I specifically mentioned a few studies.  He shrugged his shoulders in sincere uncertainty and said, "I can't say.  What do I know, I am only a surgeon."  While one could argue that he should have some resources to refer patients to, you have to admire the common down-to-earth honesty and humility.  He stands out, not for knowing everything he should know, but for just admitting his limited knowledge.

The shame is, that this is remarkable.
Title: Re: DMSO and DMSO based Solutions
Post by: ComeBacKid on February 28, 2007, 12:44:22 AM
Soxfan,

Thanks for adding your experience with thackers, i have heard of your good results, but I wanted everyone else to.

Tim,

The ved is effective, I can state for a fact that it had increased my flaccid size, mainly in length, it took daily usage for about 3 months until I saw results.  I should also state I hold each erection for about 30 seconds to a minute.  I do about 10-15 reps.  My erections are very full as well now and my penis appears thicker when erect.  I honestly believe that the VED keeps the blood vessels clear and open, and stretches that tunica.  Hopefully more people on here will post of their good results with thackers and the VED.

ComeBackid
Title: Re: DMSO and DMSO based Solutions
Post by: hopeful on March 02, 2007, 06:54:54 AM
HI Rzz..

This is Hopeful,

You did read it wrong- I have not tried it yet- I am trying to find out if anyone has had any success-

Please let me know- I am not taking any drugs at all!- WHat is the particular enzyme in the vinegar?- How long should you take it?-

Thanks,

Hopeful


Hopeful,

I'm not sure I'm reading your post correctly. It seems as if you may be saying you are mixing other drugs with DMSO and using that. If this is what you are doing, I STRONGLY urge you to STOP. One of the major factors of pharmaceuticals is the way they are introduced to the system.   

Title: Re: DMSO and DMSO based Solutions
Post by: hopeful on March 02, 2007, 06:57:49 AM
Hey ComeBackid - this is Hopeful- How are you doing- Please let me know what you did,, how much improvement as far as deformity, size, etc- what pump did you use.. and what other treatments- DMSO, Thackers, etc.?- what about Soxfan- what is this?

Hopeful

Soxfan,

Thanks for adding your experience with thackers, i have heard of your good results, but I wanted everyone else to.

Tim,

The ved is effective, I can state for a fact that it had increased my flaccid size, mainly in length, it took daily usage for about 3 months until I saw results.  I should also state I hold each erection for about 30 seconds to a minute.  I do about 10-15 reps.  My erections are very full as well now and my penis appears thicker when erect.  I honestly believe that the VED keeps the blood vessels clear and open, and stretches that tunica.  Hopefully more people on here will post of their good results with thackers and the VED.

ComeBackid
Title: Re: DMSO and DMSO based Solutions
Post by: soxfan on March 03, 2007, 05:35:44 PM
Hopeful,

I posted my very positive experience using the Thacker Formula. You should put in some time and read the thread at the bottom of the page entitled: powerful home remedy/Thacker Formula.

The ingredients are safe and inexpensive but you have to use it for 6/7 days a weekd, 2 hours a day and for upwards of a year or more. Those who say it doesn't work probably used it sporadically for a month or two and then gave up, it is a long term treatment that requires some commitment.
Title: Re: DMSO and DMSO based Solutions
Post by: hopeful on March 11, 2007, 10:20:02 AM
Nick... where are you- what happened with the DMSO?- ANy improvement.. Please let us know.

Hopeful
Yes Joshua I am going to try it again. I stated before but I think I had the mix off.
Title: Re: DMSO and DMSO based Solutions
Post by: Rzz on March 13, 2007, 03:31:21 AM
Hopeful,

Yes people have reported positive results using the formula. Some are contributors to this forum. However, it has worked better for some than others and for some it has not worked at all. Like most treatments, improvement is slow and takes patience. I'm not trying to discourage or encourage you to use the formula. That is a decision you will have to make yourself, but in all my research and all those who have reported to me I have not found one that had any devastaing side effects. The two main side effects reported to me were an initial burning in the first phases of treatment and unpleasant odor from the breath or when one heavily prespires. I would like to give you or anybody thinking of using the formula some advice; When ever in doubt about anything to do with using the formula i.e. mixing it, applying it etc.., "Don't assume, always ask before taking the next step."

By the way, most people think that burning sensation they get when they first use the formula is caused by the DMSO. It is not. It is caused by the acid in the vinegar. 

There are different types of enzymes in Apple Cider Vinegar. One that comes into play here is called Pectin.

The DMSO is the carrier
The Castor Oil is the base that holds it together as well as neutralizes the acid in the vinegar.
The Apple Cider Vinegar provides the enzymes.

Good luck and let me know if I can help you further,     Rzz

HI Rzz..

This is Hopeful,

You did read it wrong- I have not tried it yet- I am trying to find out if anyone has had any success-

Please let me know- I am not taking any drugs at all!- WHat is the particular enzyme in the vinegar?- How long should you take it?-

Thanks,

Hopeful


Hopeful,

I'm not sure I'm reading your post correctly. It seems as if you may be saying you are mixing other drugs with DMSO and using that. If this is what you are doing, I STRONGLY urge you to STOP. One of the major factors of pharmaceuticals is the way they are introduced to the system.   


Title: Re: DMSO and ENZYMES
Post by: hopeful on March 13, 2007, 04:29:22 AM
Thanks for getting back to me- I am impressed with what I have read thus far. As for the enzymes- I am a firm believer in them- and feel they may hold the key- in solving the Peyronies Disease problem- As you know- AUxulliums new wonder drug is nothing but an enzyme being packaged as a drug. (Collagenease) I am wondering now with all the new material about enzymes- including the Protease enzymes as wellas the Nanokanease and Serepetease- (Neprinol formula- only oral) if these enzymes could be mixed with DMSO - as a carrier, as they are much stronger then Pectin in eating fibritic material and plaque...  I am personally doing research with a small drug company.. and will discuss the DMSO as a carrier,, will keep you posted

Hopeful

There are different types of enzymes in Apple Cider Vinegar. One that comes into play here is called Pectin.
The DMSO is the carrier


Title: Re: DMSO and DMSO based Solutions
Post by: Tim468 on March 13, 2007, 10:16:05 AM
Pectin is not an enzyme. It is a complex made up of different polysaccharides linked together. It is primarily used to thicken jam.

Like a lot of stuff one can read here, the information is not always accurate. Pectin has a pro-health effect by serving as a source of fiber in the diet - but as a way to cure Peyronies... I do not see a way for it to help.

Tim
Title: Re: DMSO and DMSO based Solutions
Post by: Rzz on March 13, 2007, 08:48:41 PM
Pectin is not an enzyme. It is a complex made up of different polysaccharides linked together. It is primarily used to thicken jam.

Like a lot of stuff one can read here, the information is not always accurate. Pectin has a pro-health effect by serving as a source of fiber in the diet - but as a way to cure Peyronies... I do not see a way for it to help.

Tim
You are correct Pectin in itself is not an enzyme. I should have written Pectinase. I write Pectinase as Pectin for short in all my notes and that is how I transfered to the last post. Pectinase is an enzyme.

Pectin is indeed used to thicken jams, however pectin also serves a purpose in the fruit or plant it is in. Pectin is what holds the plant or fruit together. The way pectin is made to thicken jams is caused by Pectinase (a enzyme).

Pectinases are produced during the ripening process of many plants and fruits (including apples), where together with cellulases they "soften the cell walls." This byproduct of the softening is the thickening agent for jams. Pectinase causes the degredation of cell walls holding many plants and fruits together, including apples.

Tyrosinase, among others, is another cell degrading enzyme found in apples.

Rzz

Title: Re: Thackers Formula Revised
Post by: hopeful on March 31, 2007, 07:05:10 PM
Hi Barry...

I Just found a supply of 99.9% pure DMSO- Here is what I am thinking- instead of using vigear, I am thinking of using the following enzymes:

Protease - dissolves fibrin -
Nattokinase - the same
Serrapeptase - derived from the silk worm- eats the fibin as welll- plaque, etc..

I would love to hear from you first before doing this- The dmso is the carrier...

Please let me know..
Hopeful

By request I am posting a newly revised version of the Thacker Formula to this topic.


The formula CAN be premixed. How many days in advance were not discussed with Thacker but all indications lead to 3-5 days. The premixed batch must be sealed when not in use and kept at room temperature. (DO NOT refrigerate premixed batches). The formula is comprised of 70%DMSO-20%Apple Cider Vinegar-10%Castor OIL.
Title: DMSO
Post by: maxmoreno on August 30, 2007, 06:19:28 PM
 Hello,
 
 I have reviewed the information for DMSO on www.dmso-use.com   (http://www.dmso-use.com)
 and I was wondering if somebody has experienced this medicine. Can we consider this as a common way of healing?
 
 Thank you.
Title: RE: Maxmarino - Common Way of Healing
Post by: ComeBacKid on August 31, 2007, 10:58:55 PM
Maxmoreno,

Many months ago I spent considerable time reviewing the dmso information, which is a PART of thackers formula.  I can't recall a single person telling me they were healed from either DMSO or thackers formula.  I know of no scientific studies done on either as well.  I would say with confidence we can't consider this a common way of healing.  However it may still be worth looking into, and appears to be safe.  One of our forum members Barry, spent considerable time himself dealing with thackers, and claims to know of people it healed.

Comeback
Title: Re: DMSO and DMSO based Solutions
Post by: ocelot556 on October 03, 2007, 09:05:59 PM
Hi! Since you were all so very helpful with my other questions (on different topics - I've been without PC access for a while, so my apologies for not thanking you all - especially Hawk, Liam and OldMan!) I've got another one for you. Obviously, about DMSO.

I bought a bunch of it after reading about Thacker's formula, A bottle of 99% pure, a mix of 70% DMSO and 30% Aloe Vera, and a cream of DMSO mixed with aloe and vitamin E.

I've been combining the pure DMSO with 12,000 IU Vitamin E and, from time to time (to combat inflammation and hardening of the plaques in my Peyronies Disease) I apply it directly. I only leave it on for 5-10 minutes, but when I do this for a few days on end I tend to feel better.

My Peyronies Disease acts up sometimes after sex or masturbation, so I tend to use it afterwards - but I'm constantly worried.

All of the DMSO websites claim it's completely safe, but sometimes it feels like they're just trying to "sell" the drug. I don't trust the FDA worth a damn, so I don't beleive that DMSO is unsafe either (it's just not profitable for the pharma companies who've bought off the FDA).

I'm worried about what's being carried through the tissue by the DMSO, and how it might affect me. I don't overdo it - I use it maybe four or five times a month - but every time I do I'm paranoid that the soap I use to wash it off is being carried through, the minerals in my shower water are being carried through, the dye of the boxers I pull on afterwards is being carried through.

I guess I'd just like to be assured that it's either not that dangerous, or hear from people who use it without problem. Since I'm convinced that Propecia gave me my Peyronies Disease in the first place, I'm so incredibly wary about using MORE chemicals to help myself. Erk. Any advice would be appreciated.
Title: Re: Ocelot- NO NO DMSO
Post by: Liam on October 04, 2007, 05:38:15 AM
If DMSO were the cure, everyone would know it.  It is not a cure.  I would not use it myself, but have heard of no serious consequences.  I do think your concerns are justified, though.  Try taking ibuprofen for the inflammation (I'm serious).

I am no fan of government agencies.  If you want something screwed up, create a bureaucracy around it.  The FDA has huge problems.  I do trust them more than companies trying to sell you something, though.  You can't buy off every employee of the FDA.  If something really works, the word will get out.

I don't mean what I am going to say in a mean spirited way.  Propecia makes a nice scapegoat.  If it were responsible for everything some of these websites say, it would have been pulled, no doubt.  I'm just saying to keep an open mind about the cause.  Don't be convinced by speculation.
Title: Re: DMSO and DMSO based Solutions
Post by: soxfan on October 04, 2007, 02:07:46 PM
ocelot,

I have been using dmso almost everday as part of the Thacker formula for over a year now. It works and I have never had any adverse reactions.

Cheers.
Title: Re: Soxfan - Hopeful News
Post by: Liam on October 04, 2007, 03:01:06 PM
Soxfan,

Do you think you will be completely free from plaque due to Thackers?  If so, based on improvement seen in a year, how long do you estimate it will take?  Will you run through the improvements you've seen so far?   Maybe I am wrong about this.

Liam
Title: Re: DMSO and DMSO based Solutions
Post by: ocelot556 on October 04, 2007, 03:10:55 PM
Thanks soxfan. It's good to hear that people are using this stuff safely, beyond the claims on such websites as "the doctor who invented DMSO" or websites that tell you how safe and effective it is...and then go on to try and sell you bottles of the stuff in the next paragraph.

And Liam - I don't beleive my Peyronies Disease was caused entirely by Propecia - but I beleive that there must be a relationship between wound healing in the TA and testosterone/estrogen levels in the body. Since Propecia alters your testosterone and attempts to drive it down so that the specific androgens targetting your hairloss can't bind with follicles...I don't think it's a great leap of logic to assume that in the process, it drove down (or up, if estrogen is the culprit) whatever hormones my body needed to adequately recover from what must have been that initial trauma.

I just lay the blame on the medicine for the same reason you might blame a poorly-made anticoagulant if someone took it, cut themselves accidentally, and bled to death. It's really the wound itself that's to blame, but the underlying cause of it failing to heal would be the effects of the medicine.

And yeah, I might be more forgiving on the FDA if, despite my suspicions about propecia, there weren't horrendous drugs being approved like Vioxx or the ones you see in the commercials. I've actually seen ones that list side effects as "lymphoma and some rare cancers"!! How is the FDA letting this stuff through, unless they are distracted by big lobbyist paychecks...
Title: Re: Soxfan - Hopeful News
Post by: soxfan on October 06, 2007, 03:00:20 PM
Soxfan,

Do you think you will be completely free from plaque due to Thackers?  If so, based on improvement seen in a year, how long do you estimate it will take?  Will you run through the improvements you've seen so far?   Maybe I am wrong about this.

Liam

Liam,

I think that you are wrong about dmso. I started using the Thacker formula before any other treatment and after a couple of months a piece of plaque disintegrated leaving a small dent. I could "feel" it working in that during treatment I felt an itching where the scar tissue was and after treatment the peinle tissue was much more elastic.

I have since added the ved and pav cocktail to my regimin and I always pump after using Thacker formula to stretch the weakened scar tissue. It has worked very well and I have recovered most all of my length and I now have more frequent erections and much better sensation. It may take another year but I expect to be fully cured. I think that most guys try something for a couple of months and quit when they don't see instant results, you have to stick with it!

ocelot,

You are right about propecia being the culprit. It kills dht levels and that leads to damaged penile tissue even in the absence of any trauma. I posted a study here a year ago confirming that hypothesis and I will repost here or you can type "androgens" in the search function.

Cheers.

Hi All,

I am still investigating the role of androgens or lack of them in Peyronies Disease and I came across a very interesting article. It is rather long so I will only post the conclusion and a link.

 
ISI Impact Factor (2003): 1.064
 
     
  Editor-in-Chief
Shao-Zhen Qian,PhD,Pharmacology
   
-------------------------------------------------------------------------------
 
Effect of androgen deprivation on penile ultrastructure

Zhou-Jun SHEN1, Xie-Lai ZHOU1, Ying-Li LU2, Zhao-Dian CHEN1

1Department of Urology, First Affiliated Hospital, 2Department of Endocrinology, Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University , Hangzhou 310003, China

Asian J Androl 2003 Mar; 5: 33-36             


--------------------------------------------------------------------------------

Keywords: corpus cavernosum; tunica albuginea; androgens; penis; scanning electron microscopy
Abstract
Aim: To investigate the ultrastructural changes of penile corpus cavernosum and tunica albuginea in rats treated with castration or finasteride. Methods: Eighteen male Sprague-Dawley rats of nine weeks old were randomly divided into three groups with 6 rats each. Group A served as the control, Group B was castrated and Group C, treated with finasteride. Four weeks later, rats were anesthetized and blood samples obtained for the determination of serum testosterone (T) and dihydrotestosterone (DHT) levels; penile tissues were taken for scanning electron microscopy. Results: The T, free T and DHT levels in Group B and the DHT level in Group C were significantly lower than those in Group A (P<0.05). The tunica albuginea was significantly thinner in Group B than that in Group A (P<0.05), but there was no significant difference between Group C and Group A (P>0.05). Elastic fibers in the tunica albuginea of Group A were very rich and arranged regularly and undulatedly, but in Group B, most of the elastic fibers were replaced by collagenous fibers. In Group C, the tunica albuginea was mainly composed of thick and irregular-arranged collagenous fibers. In Group A, there were abundant smooth muscle fibers in the trabeculae of corpus cavernosum, but they were much less in Group C and scarce or even disappeared in Group B. In Groups B and C, the diminished/disappeared smooth muscle fibers were replaced by irregularly arranged collagenous fibers. Conclusion: In rats, androgen is essential for maintaining the normal structure of penile tunica albuginea and corpus carvenosum.

1 Introduction

Androgen is vital for the development of external genitalia in male mammals. In adult males, androgen is essential for the expression of normal libido, but seems to be not indispensable to the erectile activity [1]. We indicated that the serum testosterone (T) and free testosterone (FT) levels were significantly lower, the tunica albuginea much thinner and the penile corpus cavernosum contained less smooth muscles and more collagenous fibers in the elderly rats than in the young and middle-aged rats [2, 3]. Zhang et al [4] pointed out that castration induced apoptosis of penile corpus cavernosum in mature rats, which was prevented by T supplementation. This work suggested that the changes in androgen level might affect the morphology of the penile corpus caver-nosum, but the effect of androgen deprivation on the ultrastructure of the erectile tissue was not available so far in the literature. The present study was designed to elucidate this point in rats.

2 Materials and methods

2.1 Animals and treatment

Eighteen male Sprague-Dawley rats, 9 week old with body weight of 345¡À45 g, were purchased from the Experimental Animal Center of this University. They were randomly divided into three groups with six rats each and were maintained in a 12 h light/12 h dark animal room with free access to food and tap water. Group A served as the control, Group B was castrated and Group C, gavaged with finasteride at a dose of 4.5 mg.kg-1.day-1. Four weeks later, rats were killed by intraperitoneal injection of ketamine and phenobarbital sodium and blood samples were obtained for the determination of serum total and free testosterone (T & FT) and dihydrotest-osterone (DHT) levels with radioimmunoassay; penile tissues (tunica albuginea and corpus cavernosum) were taken from similar site for scanning electron microscopy.

2.2 Scanning electron microscopy

The penile tissues were washed with physiological saline, fixed in 2.5 % glutaraldehyde (pH 7.2~7.4) and washed three times in 0.1 mol/L phosphate buffer saline (PBS). The samples were then post-fixed in 1 % osmium tetroxide for 2 h, dehydrated in graded ethanol solutions and dried by the critical point drying method. The dried samples were then mounted on suitable carriers, coated with gold and examined under a scanning electron microscope (Leica-Stereoscan 260,UK).

2.3 Statistical analysis

Data were expressed in mean¡ÀSD and processed with statistical package of SPSS 10.0. Analysis of variance was performed with the t-test. Significance of difference was set at P<0.05.

3 Results

3.1 Androgen level

The serum concentrations of T, FT and DHT are shown in Table 1. The T, FT and DHT levels in Group B and the DHT level in Group C were significantly lower than those in Group A (P<0.05). There were no significant differences in the T and FT levels between Groups A and C (P>0.05).

Table 1. Serum T, FT and DHT levels. bP<0.05, compared with controls.

Group
 n
 T (nmol/L)
 FT (pmol/L)
 DHT (pg/mL)
 
A (control)
 6
 13.95¡À10.89
 43.91¡À25.85
 106.2¡À57.3
 
B (castrated)
 6
 0.79¡À0.51b
 1.83¡À0.15b
 48.4¡À8.6b
 
C (finasteride)
 6
 11.03¡À5.68
 47.33¡À32.45
 47.1¡À16.5b
 

3.2 Ultrastructure of tunica albuginea

The thickness of tunica albuginea was listed in Table 2. It was significantly thinner in Group B than in Group A (P<0.05), but there was no significant difference between Groups C and A (P>0.05). In Group A (Figure 1), the elastic fibers in tunica albuginea were very rich and arranged regularly and undulatedly, while in Group B (Figure 2), the elastic fibers were mostly replaced by collagenous fibers. In Group C (Figure 3), the regularly-arranged elastic fibers were not seen and replaced by thick and irregularly-arranged collagenous fibers.

Table 2. Thickness of tunica albuginea (mean¡ÀSD). bP<0.05, compared with control.

Group
 n
 Thickness (mm)
 
A (control)
 6
 0.16¡À0.03
 
B (castrated)
 6
 0.04¡À0.01b
 
C (finasteride)
 6
 0.14¡À0.03
 

Figure 1. Ultrastructures of tunica albuginea, Group A. (¡Á300)

Figure 2. Ultrastructures of tunica albuginea, Group B. (¡Á300)

Figure 3. Ultrastructures of tunica albuginea, Group C. (¡Á300)

3.3 Ultrastructure of corpus cavernosum

In Group A (Figure 4a & b), the smooth muscle fibers in the trabeculae were rich and contained a few elastic and collagenous fibers. Structure of the sinusoids was perfect and clear.

Figure 4a & b. Ultrastructures of corpus cavernosum, Group A. (a¡Á300, b¡Á900)

In Group B (Figure 5a & b), the corpus cavernosum was mainly composed of a large amount of collagenous fibers, which were thick and irregularly arranged. Smooth muscle fibers in the trabeculae were diminished or completely disappeared. The sinusoids were markedly depressed and narrowed.

Figure 5a & b. Ultrastructures of corpus cavernosum, Group B. (a¡Á300, b¡Á900)

In Group C (Figure 6a & b), the corpus cavernosum also contained a considerable amount of thick and irregularly-arranged collagenous fibers, but the degree of fibrosis was not so marked as in Group B and the types of fibrosis were different between these two groups. The sinusoids of Group C were partially depressed, but the structure of the sinusoids was still retained.

Figure 6a & b. Ultrastructures of corpus cavernosum, Group C. (a¡Á300, b¡Á900)

4 Discussion

The present study showed that in the castration animals, there were a high degree of fibrosis in the corpus cavernosum with irregularly arranged collagenous fibers and a marked decrease in smooth muscle fibers, while in the DHT-inhibited group, the corpus cavernosum contained quite an amount of thick and irregular-arranged collagenous fibers, but the degree of fibrosis was lower than that in the castration group. Results suggest that androgen is essential for the maintenance of normal ultrastructure of corpus cavernosum. Zhang et al [4] demonstrated that in mature rats, castration induced apoptosis in corpus cavernosum with the replacement of the apoptotic tissues by fibrous tissue. This may be one of the pathways through which androgen deprivation acts on corpus cavernosum. In the present study, the degree and type of corpus cavernosum fibrosis in the two groups were different, suggesting that T and DHT act on the corporal cavernosal tissues independently and differently. Finasteride can only inhibit the action of DHT, but not T on the corporal cavernosal tissue, therefore, the degree of fibrosis was less in the DHT-inhibited group than in the castration group.

The tunica albuginea of penis plays a major role in the erection mechanism. It compresses the subalbugineal venules, thus decreasing the venous outflow during erection and provides an inextensible fibrous frame for the erectile tissue of the penis [5]. In the normal control group of this study, the elastic fibers in the tunica albuginea were very rich and arranged regularly and undulatedly. In the castration group, the thickness of tunica albuginea decreased significantly and the elastic fibers were mostly replaced by collagenous fibers and in the DHT-inhibited group, the elastic fibers were replaced by disorganized and thick collagenous fibers. These results indicate that androgen is also essential for the maintenance of the normal structures of tunica albuginea.

It can be concluded that androgen is indispensable to the maintenance of normal ultrastructures of the erectile tissues. However, the interrelationship between androgen and the structure and function of the erectile tissue is not quite clear and sometimes even controversial, and further investigation is needed
 
http://www.asiaandro.com/1008-682X/5/33.htm


Title: Re: Soxfan
Post by: ComeBacKid on October 06, 2007, 08:09:08 PM
How long have you been pumping for?  Did that seem to help or result in no change for you?

Comeback
Title: Re:Soxfan
Post by: bodoo2u on October 06, 2007, 10:31:22 PM
Man,

That was some deep stuff. Can I safely assume that the study suggests my enlarged prostate was due to a lack of testoterone/increase in estrogen and may be the reason I wound up with Peyronies, which for me consists of a cord that runs the length of the right side of my penis?

That is a question for anyone, not just Soxfan.
Title: Re: Soxfan - Sorry
Post by: Hawk on October 07, 2007, 12:36:27 AM
I am happy you noticed a change after a couple of months into your DMSO (Thackers) treatment.  But, why no more improvement after over a year?  Another question nagging me is why it would selectively attack plaque and leave healthy tissue alone (skin or TA)?

I'm not denying your improvement.  But, based on what you've described, I can't say there is clear evidence DMSO did anything.  If it did, why has it stopped?

If there is some other evidence, let me know.  I want something out there to work!
Title: Re: DMSO and DMSO based Solutions
Post by: wiseguy on October 21, 2007, 01:26:28 PM
Hey soxfan...
Exactly what kind of apple cider vinegar do you use? Can it be bought online?

thanks in advance;)
Title: Re: Vinegar
Post by: Liam on October 21, 2007, 04:54:13 PM
Quote
Exactly what kind of apple cider vinegar do you use? Can it be bought online?

I use White House brand.  It is what is used on a salad and buy it from my local grocery (no shipping charge).  My wife just made West Indies Salad using lump white crab meat, salt, pepper, water, oil, and apple cider vinegar.  It was great!  You can also mix it with water and local honey to help with allergies and improve digestion.  I use the white vinegar in a solution with water to clean and deoderize the cat litter box.  You can also use it on your floors to freshen up the smell.
Title: Re: DMSO and DMSO based Solutions
Post by: soxfan on October 21, 2007, 10:49:06 PM
Hey soxfan...
Exactly what kind of apple cider vinegar do you use? Can it be bought online?

thanks in advance;)

wg,

I use Bragg brand organic apple cider vinegar, make sure you use organic that contains the "mother". The "mother" is the floating white stuff that purportedly has beneficial enzymes in it.

Hawk,

I don't know why it works but I just know that in lieu of any coincidences it helped my condition improved greatly. My length has returned, blood flow and regular erections too, I am just now finding that regaining my lost girth is coming very slowly.

Heck, the Thacker formula is cheap and harmless so why not give it a shot. Just make sure you use it every night, for two hours for at least a year to give it a fair shot to work.

cheers.
Title: Re: DMSO and DMSO based Solutions
Post by: Tim468 on October 22, 2007, 09:51:14 AM
I may try that - though I expect a fall-off in the frequency of evening fellatio.

Tim
Title: Re: Tim
Post by: Hawk on October 22, 2007, 12:12:36 PM
Tim,

Now that you bring it up,what is the molecular weight of lipstick?  It could possibly be carried into the tissue.   ;)
Title: DMSO and DMSO based Solutions
Post by: bodoo2u on October 22, 2007, 09:45:01 PM
OK, this is messing with my head, I mean it's just too much for me to understand. I thought the Thackers Formula was some type of multi-component formula and here it is just three ingredients. I know where to get castor oil and the Bragg's ACV because i frequent healthfood stores. But where do I get the type of DMSO that is most recommended for curing Peyronies Disease. Is there a specific mixture? Please Help!! And yes, I will read the entire formula before i apply it, but I just want to know what to buy so I can get it in the house and have it ready. 
Title: Re: I don't get it!
Post by: Liam on October 23, 2007, 06:13:52 AM
What is the rationale for this working?  In other words, what is in it that could possibly work?

Just a thought.....If you used Balsamic vinegar, would you get a "woodie"?
Title: Re: Bodoo2u
Post by: Hawk on October 23, 2007, 03:38:14 PM
I don't think the very strongest promoters of 'Thacker" would ever refer to it as a "cure"!
Title: Re: Thackers Formula Revised ***REPOST***
Post by: Liam on October 23, 2007, 05:52:30 PM
Here is a post from Barry who personally spoke with Thacker.  Thacker claimed to be 90% cured.    It took me 2 minutes to find this post just by scrolling back through older posts.  For the sake of disclosure and honesty, I am not a believer in this method.  But, this is the 411  8)

By request I am posting a newly revised version of the Thacker Formula to this topic.


Thacker Formula-Revised…12/17/05

An Informational,

My communications with Thacker confirmed much of what was believed from the little information initially given. The discussions covered the following, Thackers use and results of his Grandfathers Formula…..Doctor Thacker, Thacker stated that Peyronies Disease starting with Doctor Thacker, who suffered from Peyronies Disease, as well as his uncles, father and himself. It seems to indicate in theory that Thackers family from his Grandfather to himself had a Genetic Pre-Disposition to this disease. Thacker indicated to me that DMSO and its quality was of the utmost importance, as expressed to him by Doctor Thacker and clarified many times. Unfortunatly, the source of Doctor Thackers DMSO is unknown. This does not negate the other two ingredients in any way and their importance to the formula. Thacker confirmed the 70%-20%-10% mixture as what was used by him. Thacker did stress that a high quality Apple Cider Vinegar be used, I told him that many men were using organic ACV and he did not agree nor disagree, but additional research indicated and confirmed that Organic ACV should be used. Castor Oil is generic in nature, so any brand will do. Thacker said that his Grandfather used the formula on men with Dupuytrens Contracture, aka (DC), he did not mention results, but it was used never the less.

Taking nothing from Thacker, it must be understood that he was for the most part a “user” of this formula, and did not in fact know much as to what the components did or why. His Grandfather mixed it for him; Doctor Thacker pre-mixed the formula, and gave it to him as needed with instructions on how to apply it.



I suggest strict self-obedience with the treatment and trust that it will work. It takes some time.
You must keep the wrap soaked during application.
The garlic odor from the application could be bathed off and a scented cream such as Aloe Vera applied to the penis after application, but the internal odor that omits through the skin pores and breath, is something you have to live with, and I can only suggest strong breath mints and wear cologne to envelop the smell. That will usually cover it. My own personal research has concluded that gently massaging the plaque after application is acceptable as long as it does not incur pain. Do this for about five-ten minutes.


THE FOLLOWING IS A DIRECT QUOTE FROM THACKER TO ME

QUOTE
“I usually followed my evening application with a hot bath and massaged the plaque forcefully but not painfully. It took about three to four months for me to start seeing results and then positive results started coming quickly. The hard nodules will suddenly start getting soft. They may break apart. Once that starts happening things improve fast. You should realize increased erection quality right off the bat. The DMSO
will smooth the muscle in the penis.”
“Once the hard nodules start getting soft or breaking up into bits. It took about six more months of application and message to finish it off. My penis then healed almost back to pre-Peyronies Disease. I would say that I am 90% where I was. I no longer have any hard pieces of plaque in my penis. I have one small indentation left where a huge piece of plaque was that did not heal all the way back. The curve will reduce slowly as plaque resolves. I started with a 50 degree curve when it was at its worse, and now, no noticeable curve”
END QUOTE


Mixing Procedure,

You MUST, wash your hands with any type of hand or body soap prior to the mixing process.
The formula CAN be premixed. How many days in advance were not discussed with Thacker but all indications lead to 3-5 days. The premixed batch must be sealed when not in use and kept at room temperature. (DO NOT refrigerate premixed batches). The formula is comprised of 70%DMSO-20%Apple Cider Vinegar-10%Castor OIL. In order to mix the formula use three separate 10cc syringes and draw the liquid up to the 1, 2, or 7 mark depending on the liquid. Then squirt each one into a small glass bowl and mix well with an eyedropper.


Application Method.

Warm the formula prior to use; this should be common to its application. Soak the mixture on a flannel sheet of cloth (NO coloring, MUST be white) or an appropriately sized strip of sterilized gauze. Wrap the cloth completely around the penis, then to hold it in place use white medical tape, rubber bands or uncolored string. Do this application once daily (the evening hours would be preferable to most), and as consistently as possible through the week. The duration in time should not be less then 1/2 hour, although 1-2 hours is favored. DO NOT refrigerate pre- mixed batches, if you do, throw that batch away. Also, if you get redness or blistering, discontinue use and apply Diaper Rash Medicine or Aloe Vera to ease the problem and correct it. Once corrected continue treatment.


CAUTION!
DMSO is a very safe solvent when purchased in a pharmaceutical grade of at least 99.96% purity.
While the bottle is open and/or the batch is being pre-mixed be very cautious and not get it into you eyes. If you do go the nearest E.R, they will know how to treat you with an eyewash.
Also, pure DMSO is not to be taken internally. The same conditions apply as to the above remedy.

DMSO is a very powerful delivery agent, meaning that it will transfer thru your skin and into your body anything on your hands, so it MUST be used under Sterile Conditions.


DMSO on line Purchase Sites,

www.webvitamin.com Natures gift
www.lifesvigor.com Natures Gift
www.herbalremedies.com Clinic Service Co.
www.kornax.com Rich’s



I am not a Doctors and do not profess to be, I am however, an avid researchers and bring this treatment to you with no promise of efficacy but, but most assuredly a sparkle of hope.
This formula is an ALTERNATIVE, non-Medicinal treatment. Years of research have been invested by me and another Peyronies Disease survivor who’s research efforts played a solid role in putting this formula together thus allowing me to put this formula in writing for all Peyronies Disease sufferers to try. Your Doctors may attempt to convince you that the use of this treatment is flippant; the ultimate decision to use this treatment is up to you. The general statement Doctors use is, “it has no basis in science”, to that I say, tell that to the many men who have had efficacious results. Also, there are NO RX contraindications to this formula and it’s not invasive. Used as directed, it is as dangerous as taking an aspirin.


Good Luck,
Barry, aka, PDFTD,
Peyronies Disease researcher,Advocate and Survivor for 12 years
 
 
Title: Re: DMSO and DMSO based Solutions
Post by: bodoo2u on October 23, 2007, 06:23:45 PM
Hawk,

I didn't mean to write "cure"; I know it's just a treatment that may or may not yield results. I still may or may not use it, especially if it causes scarring. Heck, It's funny-looking enough without adding scars to it.

Liam,

Thanks for reposting the instructions. You guys are the greatest.

Hey, I'm getting more comfortable with weating my traction device under my clothes. I guess I look like an old man when I'm trying to climb stairs, because I don't lift up my legs very high. LOL
Title: Re: DMSO and DMSO based Solutions
Post by: soxfan on October 23, 2007, 11:53:50 PM
Gents,

The following article about dmso is a must read, imho. :)

DMSO’s Many Potential Medical Applications
Since the early 1960s, DMSO’s pharmacological actions and efficacy have been documented in hundreds of laboratory studies. According to Dr. Stanley Jacob, DMSO holds promise in treating the following conditions:

Alzheimer’s disease. DMSO has been shown to dissolve amyloids, the proteins that occur in the hallmark brain lesions of patients with Alzheimer’s and almost invariably lead to the functional loss and eventual death of brain cells.

Arthritis. With its ability to penetrate tissues, DMSO shows value in reducing pain and inflammation in osteoarthritis, rheumatoid arthritis, and possibly gout.

Atherosclerosis. In laboratory animals, DMSO has demonstrated its ability to retard the development of atherosclerosis induced by dietary cholesterol, as well as suppress the accumulation of cholesterol in tissues despite severe hypercholesterolemia (elevated blood levels of cholesterol).

Down’s syndrome. Researchers have noted that when children born with Down’s syndrome were treated with DMSO, mental and neurological functions improved in a number of areas.

Drug extravasation injury. When chemotherapy drugs exude into surrounding tissues (extravasate), the effects are highly damaging. DMSO application significantly improved anthracycline-associated extravasation tissue injury in a study conducted by Stephen B. Strum, MD, a member of the Life Extension Foundation’s Scientific Advisory Board.

Fibromyalgia. According to Dr. Jacob, 70% of fibromyalgia patients he treated with DMSO for several years experienced benefits with no side effects. He believes these effects were due to pharmacological actions of DMSO such as free-radical scavenging, analgesia, anti-inflammation, softening of scar tissue, reduction of muscle spasms, and stimulation of healing.

Herpes. DMSO has been used to enhance penetration of alpha-interferon ointment in the treatment of herpes.

Interstitial cystitis. Instilling DMSO in the urinary bladder is an FDA-approved palliative treatment for this chronic inflammatory condition.

Malignancy. Researchers concluded DMSO exerts a significant survival advantage in gastric cancer.

Plastic surgery adjunct. DMSO has been shown to aid healing and reduce pain and swelling.

Prostatitis. Significant symptomatic relief occurred when DMSO was injected by catheter into the prostatic urethra.

Reflex sympathetic dystrophy. DMSO helps relieve the pain of this condition, an autonomic nervous system disorder characterized primarily by overwhelming pain in the extremities. Dr. Jacob notes that in Holland, a physician is breaking the law if he does not prescribe topical DMSO for reflex sympathetic dystrophy.

Scleroderma. In basic work done at the Cleveland Clinic, topical DMSO was found to have an anti-inflammatory effect while increasing blood supply to the skin.

Spinal cord injury. Data shows that if DMSO is given intravenously within the first 45-60 minutes after injury, the number of laboratory animals that recover was much higher than in those not receiving DMSO. Dr. Jacob says this is an area he would like to pursue, noting, “If we have 10,000 severe spinal cord injuries per year in the US—quadriplegic and paraplegic—there could be fewer patients who will need long-term care.”

Stroke. DMSO combined with a sugar that fuels energy production was well tolerated in elderly stroke patients, and could be of benefit in reducing neurological disability after stroke.

Ulcerative colitis. In controlled human studies, orally administered DMSO produced some improvement in the condition.
http://www.lef.org/magazine/mag2007/jul2007_cover_dmso_02.htm

bodoo2u,

I get my dmso(99.9% pure, 16oz liquid)  from the following on-line retailer. I of course have no affiliation with the company, just trying to be of help. :)
http://www.herbalremedies.com/dmso.html?source=google&engine=adwords!32&keyword=%28dmso%29&match_type=&gclid=CJym6rzQpo8CFQGdPAodqkIcRw

Cheers.



 
Title: Re: Soxfan - Where is the Beef
Post by: Hawk on October 24, 2007, 12:42:48 AM
I am open minded but I did not see the specifics of ONE SINGLE study.  If those unbelievable statements are true, there must be a ton of information available on the studies, the details of what controls were in place, the results, etc.

If you know of any such documented studies by reputable, unbiased sources, please give us the unformation.

If you don't, then it remains nothing but another outlandish internet claim.
Title: where should i get dmso?
Post by: whygodwhy on November 14, 2007, 09:27:24 PM
im not sure whether or not i should buy the 16 oz dmso listed below or pay extra for a brand from peyronies-disease-help.com that has msm and paba in it as well:

http://www.natural-complementary-medicine.com/index.asp?PageAction=VIEWPROD&ProdID=18 (http://www.natural-complementary-medicine.com/index.asp?PageAction=VIEWPROD&ProdID=18)

its twice as much money for a quater the amount

will a cheaper brand thats 99% pure work just as well?
and does it matter if i get gel or spray or concentrate?
Title: Re: DMSO Cheap
Post by: Liam on November 15, 2007, 06:20:44 AM
WGW,

IMHO, You will get the same results from either.  ;)
Title: Re: where should i get dmso?
Post by: soxfan on November 15, 2007, 01:37:58 PM
im not sure whether or not i should buy the 16 oz dmso listed below or pay extra for a brand from peyronies-disease-help.com that has msm and paba in it as well:

http://www.natural-complementary-medicine.com/index.asp?PageAction=VIEWPROD&ProdID=18 (http://www.natural-complementary-medicine.com/index.asp?PageAction=VIEWPROD&ProdID=18)

its twice as much money for a quater the amount

will a cheaper brand thats 99% pure work just as well?
and does it matter if i get gel or spray or concentrate?

WGW,

Just get the plain 99.9 dmso just as Thacker himself suggested. The ms, paba and other stuff is not necessary.

Cheers.
Title: Re: DMSO and DMSO based Solutions
Post by: whygodwhy on November 15, 2007, 11:13:17 PM
thanks guys, ill go ahead and order the 99.9% DMSO

im looking forward to trying out the thacker's formula.  i read in a post that dmso can be risky, is that true?  i know its bad to get in your eyes or swallow (ie common sense)  but if i do it wrong somehow could it make my Peyronies Disease worse? :-\
Title: Re: DMSO and DMSO based Solutions
Post by: Hawk on November 16, 2007, 08:16:44 AM
DMSO is a transdermal agent.  It will transport ANYTHING & EVERYTHING below a certain molecular weight into the tissue.  That could include everything from contaminants on your hands to dyes in any cloth that come in contact with it.

I have heard from a veterinarian that it can be demonstrated that certain dyes can be put on the palm of the hand and when DMSA is added the color will penetrate to the back of the hand.  I do know that you can often literally taste DMSO within a minute of getting it on your hands.

Wash your skin where applying it, as well as your hands, and make sure there are no dyes or contaminates on any cloth that comes in contact with the DMSO.

Wash your hands when finished to get any DMSO off before handling other things that could have chemical contaminates.
Title: Re: Just Say NO to DMSO
Post by: Liam on November 18, 2007, 07:52:03 AM
Quote
I have heard from a veterinarian that it can be demonstrated that certain dyes can be put on the palm of the hand and when DMSA is added the color will penetrate to the back of the hand.  I do know that you can often literally taste DMSO within a minute of getting it on your hands.

Now mix with vinegar and castor oil and soak your penis...

Hawk is right to encourage using caution.

This "formula" is ridiculous.  Use the DMSO to clean your floors, the vinegar (ACV) on your salad and...well... you know what the casto oil is good for.

I'm glad this info is here and you are free to try it.  I just have to throw in my objections.

BTW, I have a formula: Windex and olive oil (OO) for a "Big Fat Greek Penis" 
Title: Re: DMSO and DMSO based Solutions
Post by: soxfan on November 20, 2007, 07:23:23 PM
If anyone wishes to discuss the Thacker formula without being subjected to ridicule from people who have not used the DAMNED thing then please contact me via pm, THANKS!!!!
Title: Re: The Damned Thing, aka: Thacker's
Post by: Liam on November 20, 2007, 09:42:25 PM
Sorry Soxfan.  I call it like I see it.  My post represents my opinion just as yours do.  Although I am stongly opposed to this concoction, I would not want to remove the topic.  I am also glad you post your opinion on it.

If in the more than two years I have been posting here and reading about Thackers I had heard of one legitimate scientific study showing positive results, I might be singing a different tune.

This and the fact DMSO is a transdermal agent is the reason I will not try it. 

Go ahead and try it.  Just understand there are those who think its a hoax.  And, if it turns out to be the cure, I will eat crow, happily.
Title: DMSO Downside?
Post by: soiDisant on December 13, 2007, 12:34:15 PM
All,

I've read this thread and the other (1000 posts) related to DMSO. The only problem I see in trying the stuff is the potential for permanent damage. I might be wrong - it was alot to read, after all - but I saw no posts complaining of such damage. If it doesn't wor, it doesn't work; so long as it does no harm.

But at least one person complained about diminished erectile function while using DMSO. Can others weigh in on their experience of DMSO from this perspective? I would be most grateful to glean some kind of consensus WRT the stuff's potential for impairing erectile function. 

Thanks.
Title: Re: soiDisant - DMS0
Post by: Hawk on December 13, 2007, 01:35:55 PM
soiDisant,

Welcome to the forum.  I pretty much agree with your assessment
Quote
If it doesn't wor, it doesn't work; so long as it does no harm.

The other 1000 post thread was an achieve retrieved after it was deleted from a forum that is now pretty much dead.   Since it is an old archive, I think you will actually find few active members still around that use it although a few probably do.
Title: Re: DMSO and DMSO based Solutions
Post by: soiDisant on December 13, 2007, 03:40:06 PM
Thanks for the welcome, Hawk.

I was indeed aware that the "1000 posts" thread was a restored archive. But your comment has me wondering whether or not DMSO has fallen "out of favor" for forum members; and if so, why?



Title: Re: DMSO and DMSO based Solutions (Bakers remedy)
Post by: MichaelBaker on December 31, 2007, 12:16:40 PM
Hello group,

I just joined after I was doing some research on DMSO. I have been using DMSO in a concoction I developed for a scar and joint pain. It has worked extremely well in removing plaque and lessening scarring. It is up to you to do your homework with these chemicals and decide for yourself if it is safe for you. I will assume no liability for your errors or lack of judgement.
I only ask that you report back with the results of your own experiments. Good or bad.

I am sure this post will be given very critical reveiw for the lack of previous knowledge on my experiment, but I am sure that this will work for your affliction also (Peyronies). The DMSO is only one part of the mixture, but it is important.

Possibly more important is a product now called MMS. It is sodium chorite %28 solution, activated with lemon juice. If you can get past all the miraculous claims and try it, it has been reported to strip the plaque from clogged arteries. please go slow on this off you have any heart problems. If you want to try it before you put it anywhere special, try brushing your teeth with it for a week and see if your dental plaque is gone.

To strengthen cells and heal scarring I use a transdermal magnesium oil. I have bought it from Global Light, I dont get paid for this, buy it where you want, just make sure that you get the natural oil and not the jell.

I use natural iodine in the solution, it also promotes healthy cell function.

I use 99.9 DMSO, again buy it where you want.

Now the recipe.

20 drops of MMS

add 100 drops of lemon juice, real lemon from the plastic lemon at the grocery store works great.

let these two ingredients sit for three minutes and the acid from the lemon juice will react with the MMS. There will be a very strong smell of Chlorine gas from the reaction.
Now add one tablespoon of the magnesium oil
Now add one tablespoon of the DMSO
Now add one dropper of the iodine

stir, you will feel heat from the mixing of these things, try it on some tender skin and look for an adverse reaction. If your skin is to sensitive for the solution at 100% dilute with a small amount of distilled water.

when you get the strength that wont burn willie apply and let sit, do this as many times per day that you are able. As long as the solution has that chlorine smell it will be working, discard after the smell of chlorine is no longer present.

I am sure that the flames will be coming, but if just one or two of you try this and report back with your "cure" then the others will follow suit.

I make no claim as to being anything other than the developer of this recipe and place it freely in the public domain for all to use for personal use only. I assume no liability for any results that you may have. We just may have to develope our own health remedies when the drug companies cannot make enough profit from easily obtainable homeopathic remedies such as this.

Michael Baker
Title: Re: DMSO and DMSO based Solutions
Post by: Tim468 on December 31, 2007, 02:22:10 PM
Welcome Michael Baker,

Could you share how you came up with the ingredients that you did, and why the proportions?

Tim
Title: Re: New DMSO based formula ...
Post by: George999 on December 31, 2007, 03:06:38 PM
Michael, welcome and thank you so much for sharing this information.  While I personally do not touch DMSO, I know a number of people who frequent this forum do.  And I am sure that there are some out there who are really looking for new approaches in using it.  Certainly what works for one person may not work for another AND what is harmless to one person might create a toxic reaction for another.  After all, even peanuts can be deadly to some of us.  It is also EXTREMELY important that it be used correctly to avoid potentially devastating unintended consequences.  So I fully understand your disclaimers and anyone planning on trying it should study its use very carefully including posts on this forum by Hawk and Liam.  And this is NOT to say don't use it, it is rather to say use it very cautiously and with great respect.  You are also dead on in noting that these types of approaches are anathema to the drug companies.  They are actually very up front in explaining that they could never make enough money from selling generic commodity based solutions to even begin to pay for the R+D that goes into getting any potential treatment approved.  And, unfortunately, our government(s) do(es) not consider public health a high enough priority to fund this type of research that private enterprise cannot profitably perform.  So all I can say is that I hope some daring individual will give it a try and hopefully it proves to be a breakthrough that can benefit many.  So thank you so much for posting the information.  - George
Title: Re: DMSO and DMSO based Solutions
Post by: MichaelBaker on December 31, 2007, 08:46:36 PM
I came to this forum to give back to society. I felt compelled to help others in a way that I was helped.

The real story is the MMS protocol by Jim Humble. I don't have the time to go into that side of it for this forum. The activated sodium chlorite is his and I have personally seen mind blowing results from it. I have gotten over a dozen people started on it. It is truly amazing stuff.

The mixture I came up with was trial and error, I burnt the side of my face for a week, but the age spot I applied it to has faded drastically, enough to not be noticable anymore. I actually made the formula to be applied to my feet. That is how I fine tuned what I put in it. My feet haven't look this good since I went to high school gym class and got some fungus that I never could get rid of, at least until now. My feet are soft and toenails look as healthy as ever.

The part of this that would apply to Peronies is what it did to my scar, raised and a hard white crest. It softened and is now pink and seems to be fading still. That is why I posted to this forum. I have had no erection problems.

I understand the fear of dmso. I did a lot of reading. I know that the finest race horses in the world get dmso and some of the greatest names in sports also covertly use the stuff. I would never perpetuate a hoax, at least I believe I am honest. My hope is that some brave soul out there tries this and gets results similar to mine and feels compelled to report back to the group and maybe a lot of you would have favorable results. I could at least tell St Pete that I did try to give back a little.
Title: Re: MichaelBaker
Post by: Hawk on December 31, 2007, 09:01:23 PM
Michael,

1.  Are you saying you have Peyronies Disease and this helped?

2. Have you gotten 5 men to try this on Peyronies Disease or for other things like nice feet?

3. If the 5 men had Peyronies Disease, what forum were they on?

4. I have been on every Peyronies Disease forum around for a some years and I never heard of Jack Humble.  Who is he and where did you meet him?


You must understand that you cannot say I am too busy to go into details, just try this undocumented concoction and trust the integrity of an unknown name on the internet.
Title: Re: DMSO and DMSO based Solutions
Post by: MichaelBaker on December 31, 2007, 09:56:54 PM
points taken hawk,

"Jim Humble MMS Protocol" a simple google search yields 1290 hits
http://www.google.com/search?hl=en&q=jim+humble+mms+protocol.

This is a relatively new and unknown protocol. Very few have tried it, just seems to good to be true. There are a few forums for this protocol already, and it REALLY is beyond the scope of what I have time or inclination for. I do know that is seems to dissolve plaque and that is what ties it into Peyrones.

The activated MMS protocol combined with dmso, magnesium and iodine has only been tried by one person that I know, but then again, I am just an unknown name on the internet. I do freely offer up my time to provide what has worked for me and others I know personally, There are others in this forum already experimenting with DMSO, this is mainly for them, I feel that the MMS adds another potential booster for what they are trying to do. The magnesium and iodine are essential for healthy cell development. If this concontion is going to work, a week is probably all the time you would need to see improvement, milage will of course vary.
Title: Re: DMSO and DMSO based Solutions
Post by: Mick on December 31, 2007, 10:03:23 PM
Hawk:

See miraclemineral.org

Mick
Title: Re: MMS ...
Post by: George999 on January 01, 2008, 12:53:51 PM
Sometimes a "product"s claims are just so off the wall that one has to sleep on the whole nine yards before beginning to really see whats there.  In the case of "activated" MMS as promoted by Jim Humble, I can only conclude this:  Most of the work done in Africa on this was done by "The Malaria Solution" based in Reno Nevada.  The guys behind Malaria Solution appear to have a mining/mineralogy background, money, and a passion to serve humanity.  Jim Humble seems to be the main innovator in this venture.  Personally, I would like to see a little press on this in Africa itself, but if it is indeed a scam, then they have scammed some pretty reputable people who seemingly are involved with them.  I see little motivation for a scam, since they have made this thing so open that there is little money to be made from it.  So the question becomes, "If this thing is so good, why has it not gotten more press and benefited more people?". 

I think there are indeed answers to that question.  First of all, one has to understand that in order for a treatment to be approved, lots of very expensive testing is required.  And this is not the kind of product that could bring forth that kind of investment easily.  Secondly, although I know that Chlorine Dioxide is considered safe at sufficient dilution, it is still a potent substance and this therapy introduces it to the body in a very reactive state.  That alone would scare regulators to death, or if it didn't it should.  Using it to treat dying villagers in Africa is one thing, using it for things like Peyronies in the US is another.  At this point, the reality is, we really have no data on what the potential initial random side effects might be, nor do we have long term data to indicate long term outcomes.

And that leads to a third concern for me.  If I was dying of HIV or even Cancer, I would latch on to something like this without a lot of hesitation.  But Peyronies?  Or foot fungus?  Some of you might be willing to chance it, but I can tell you, not me.  I would be looking at a lot more conservative treatments than that.

Yet another concern for me is the whole known pharmacology surrounding Chlorine Dioxide.  For those of you who might not understand what Chlorine Dioxide is, it is actually probably one of the most whiz bang wide spectrum pathogen killers known to man.  It destroys bacteria, viruses, fungi, and parasites.  Yet it does so in concentrations that are not discernibly toxic to people.  For this reason it is rapidly replacing common chlorination for water supplies and it is on the short list of potential solutions for Homeland Security people in the US.  It is even used to cleanse human blood of HIV.  But REMEMBER, current use is all OUTSIDE of the body.  This treatment, for the first time, moves that treatment to INSIDE the body.  Hello!

Another aspect to consider is that there is simply no known way that this treatment could work against NON-INFECTIOUS afflictions like Cancer, Peyronies, and other forms of Fibrosis, UNLESS that NON-INFECTIOUS disease is in fact driven by an infectious disease, and that can happen.  My suspicion is that Mr. Humble has seen Cancer knocked out with this stuff in Africa, but in reality, it knocked out the underlying HIV and THAT cured the Cancer.  I extremely doubt that it can cure a typical case of Cancer, because the underlying pharmacology is just not there, UNLESS all Cancers are pathogenic at the core and that would be a huge stretch.  And of course Peyronies would be in the same ballpark with Cancer, not likely.

So to sum up, the likelyhood of this working on Peyronies in my estimation is slim, and the risks are high with Jim's oral solution, but at least it has APPARENTLY been tried on a wide scale.  On the other hand, at this point it would seem that we have no more than a small handful of people, if that, who have actually tried administering it transdermally with DMSO.  Personally, I see all kinds of caution flags here.  I DEEPLY appreciate that Michael has shared this with us, and I do think it is something that needs to be investigated, but personally, I would proceed with a whole lot of caution.

- George
Title: Re: DMSO and DMSO based Solutions
Post by: Tim468 on January 01, 2008, 02:09:26 PM
Dear Michael Baker

Thanks or sharing your thoughts. I was disappointed with the references - they are all anecdotal, and have no peer reviewed science. The reasons for this are well described by George, but in fact it IS possible to study non-patentable medications for other uses to "serve humanity", even though the profit motive is absent. I have participated in multi-center studies of Advil to treat chronic inflammation in cystic fibrosis, and no one was going to get rich doing that.

If someone is willing to try it, I hope to hear from them. I would be unwilling personally to try it. YMMV

Tim
Title: Re: DMSO and DMSO based Solutions
Post by: Nemo on February 27, 2008, 06:38:11 PM
Out of nostalgia, I was reading the thread on "Thacker's Formula."  I recall now that I used TF for about 9 months I believe, starting in Jan. of 2004.  At that time, I had some distal flacidity but no bend or pain.  I was using TF to see if it would do something to the scarring causing the distal flacidity.  It didn't, but it did improve my erections, very quickly in fact, as I recall.  I also remember bouts of skin blistering/peeling in the early days of using it - nothing bad enough to make me stop though.  Eventually, it seemed like it wasn't doing anything for me (other than the erection quality), so I stopped using it. 

Anyone else have memories (fond or otherwise) of Thacker's Formula?  I remember being very excited at the time as it was getting a lot of positive posts.  I really thought we were on to something!  Care to share your experience?

Nemo
Title: Re: DMSO and DMSO based Solutions
Post by: slowandsteady on June 06, 2009, 05:41:32 PM
It's about time someone gave this neglected thread some lovin'. ;)

I first found out about DMSO through the resveratrol forum (http://www.imminst.org/forum/index.php?showforum=312) at imminst.org. Folks there were discussing it as a means to enhance transdermal absorption of resveratrol. Another application was using DMSO and resveratrol topically for eczema (http://www.imminst.org/forum/index.php?showtopic=22954), where it was reported to work very well for some. The forum's goal was to get high peak plasma levels of resveratrol. The conclusion there was that transdermal application with DMSO was not the best solution for achieving this, but that it might be useful for parts of the body like joints that don't have a lot of blood circulation.

Question: does the tunica albuginea area affected by the plaques get a lot of blood? It's a "fibrous envelope" according to wikipedia. The corpus cavernosum certainly does, but that's not what's damaged.

Here are my ideas for a few things to try with DMSO:

resveratrol: it has fibrolytic properties, including in pulmonary and cardiac fibrosis (PMID 17875610 (http://pubmed.gov/17875610)). PMID 17943548 (http://pubmed.gov/17943548) is interesting too; subcutaneous injections of resveratrol reduced adhesions that were induced in rats.

serrapeptase: some evidence for it helping to clear scar tissue. It was helpful in fibro-cystic breast disease (PMID 2688125 (http://pubmed.gov/2688125)). I wonder though if this weren't more a result of it breaking down biofilms of pathogens.

nattokinase: supposedly a strong fibrolytic (here's some data (http://www.nattokinase.co.jp/en/experiments.html) from company selling it). From PMID 16899918 (http://pubmed.gov/16899918), "In vitro and in vivo studies have consistently demonstrated the potent pro-fibrinolytic effect of the enzyme".

vitamin A and the other oil soluble vitamins
: Looking back on some of the earlier postings on the Thackers formula, I see that it included cod liver oil, which is a good source of the oil soluble vitamin A. From an LEF.org article (http://www.lef.org/magazine/mag96/aug_new_therapies.htm) on fibrinogen, "High serum vitamin A and beta-carotene levels have been associated with reduced fibrinogen levels in humans". A good DMSO recipe might include the 4 fat soluble vitamins (A, D, E, and K) too.

I'll be trying some of these out and reporting back.

s&s

Edit:
potassium iodide might be important too. One hypothesis I'm researching is whether low potassium iodide intake causes the abnormal scarring in Peyronies Disease (Peyronies Disease is more common in those with gout and high blood sugar, IIRC). I'd like to try topical SSKI if I could find a source ...
Title: Re:Slow and Steady
Post by: Hawk on June 06, 2009, 11:11:27 PM
Keep in mind you need to know the molecular weight of a substance because DMSO only transports substances within a certain molecular weight range.  (I do not remember the range off the top of my head but it is easy to look up.)
Title: Re: DMSO and DMSO based Solutions
Post by: newguy on June 08, 2009, 12:03:01 AM

I do think that this method of treatment does hold some promise, but its very much a case of entering the unknown as there are so many substances that could be used, and so many variables at play. Maybe mixing several potential treatments together (vitamins, serrapeptase etc)and applying them could make a difference over time. Any treatment, even if effective, may take a long time to actually bring about results, so using individual substances would be troublesome, as cycling through them may not be a useful approach. My hunch is that this could be a very good delivery system for peyronie's though, so I'm glad some are willing to give it a try.

Title: Re: DMSO and DMSO based Solutions
Post by: slowandsteady on June 08, 2009, 01:09:02 AM
The one vitamin we know for sure would penetrate the skin is vitamin D, since this is how it works in nature.

Normally, it's produced on the skin and absorbed over a period of a day or two. Soap and water will take it right off.

s&s
Title: Re: DMSO and DMSO based Solutions
Post by: newguy on June 08, 2009, 01:28:44 AM
When I looked into topical ibuprofen, the available studies appear to suggest that in knee injuries it is absorbed through the skin and into the cartilage in much higher doses than oral doses. This at least shows that sometimes applying topically, can be as, if not more effective than oral doses. Therefore maybe using a DMSO delivery system with various substances could be more achievable than we'd first think. As hawk points out, it likely depends on the substances in question. Still, I think it's an area worthy of exploration. If substances can reach the area, I would think that it'd sometimes make sense to topically apply rather than orally.

As a child I suffered bad burns to my hand, as was told that it would be scarred for life. A school teacher advised me to apply vitamin E topically each day. I did this and in time the scar went away completely. Of course , this is not a direct comparison, but I doubt the scar would've cleared up with oral vitamin E (unless of course it would've gone naturally). Therefore getting to a problem area topically is surely a viable route if it is achievable. I'm not suggesting that using this method is an easy or effective as inflammation or scarring on the skin, but maybe it can be the next best thing.

An argued against this approach I suppose is that DMSO could transport anything into the body. A careful approach would therefore be needed. Another argued against this approach is that some would say that peyronies is more of a whole body disease which has manifested itself in the shape of peyronie's. That's valid, though I'm of the opinion that in some individuals the problem is more localised, and in others it's more of a whole body issue. Just my view. Besides, if someone applies something topically, theres nothing to stop them taking oral supplements too. I'll watch this thread with interest.


Title: Re: DMSO and DMSO based Solutions
Post by: slowandsteady on June 08, 2009, 11:14:52 PM
Other things that come to mind as potential ingredients for a DMSO recipe are niacinamide with taurine and SSKI or Lugol's solution. Oh, and let's not forget vitamin E.
Title: Re: DMSO and DMSO based Solutions
Post by: ocelot556 on June 09, 2009, 06:47:32 PM
My urologist recommended over a year ago that I try this gel that he had a natural pharmacy make for me. I posted about it a while back - it's a topical ointment made of EDTA (a chelating agent, presumably to prevent/ameliorate calcification) and ALC. The drawback? It costs 100 dollars a month. I struggled to continue it for 5 months, and saw no improvement. I think it was because I was in the inflammatory phase - being just out of college, I couldn't afford the full treatment, and since I couldn't see visible improvement in 5 months I stopped treatment.

After a new inflammatory phase and new plaques, in addition to a better-paying job, I've restarted the treatment -- but I was wondering if I could bolster the effects of the ointment by applying a layer of DMSO before applying the ointment. I was simply worried about the safety of getting the treatment elsewhere in the penis. As my situation looks more and more grim, I might feel as if I have less to lose and try it out. I will report my findings at that time. I don't even know if the EDTA or ALC will be carried transdermally by the DMSO or not, but I do remember how well just the DMSO worked to help the pain and redness of inflammation when I was using it.
Title: Re: DMSO and DMSO based Solutions
Post by: slowandsteady on June 09, 2009, 10:51:48 PM
You can always make your own. EDTA is over the counter now. ALC of course you can buy, just like DMSO. My thought is that vitamin K (K2-MK4 in the oil-based Thorne drops) might be just as good as EDTA.

I think it's a good recipe though.

My urologist recommended over a year ago that I try this gel that he had a natural pharmacy make for me. I posted about it a while back - it's a topical ointment made of EDTA (a chelating agent, presumably to prevent/ameliorate calcification) and ALC. The drawback? It costs 100 dollars a month. I struggled to continue it for 5 months, and saw no improvement. I think it was because I was in the inflammatory phase - being just out of college, I couldn't afford the full treatment, and since I couldn't see visible improvement in 5 months I stopped treatment.

After a new inflammatory phase and new plaques, in addition to a better-paying job, I've restarted the treatment -- but I was wondering if I could bolster the effects of the ointment by applying a layer of DMSO before applying the ointment. I was simply worried about the safety of getting the treatment elsewhere in the penis. As my situation looks more and more grim, I might feel as if I have less to lose and try it out. I will report my findings at that time. I don't even know if the EDTA or ALC will be carried transdermally by the DMSO or not, but I do remember how well just the DMSO worked to help the pain and redness of inflammation when I was using it.
Title: Re: DMSO and DMSO based Solutions
Post by: slowandsteady on June 10, 2009, 09:16:13 AM
I got a few 2 ounce cobalt blue bottles with eyedroppers from Ebay.

Recipe No. 1
DMSO: 10 half droppers full
Vitamin A: 40000 IU
Vitamin D: 20000 IU
Vitamin E: Jarrow Toco-Sorb, contents of 2 softgels
Vitamin K: 20 mg from the Thorne drops
ALC: 125 mg

I used it last night (10 drops or so) without any irritation this morning. I plan on first trying nattokinase by itself and then If that is gentle then adding it to the mix. This recipe has a slight orange tinge from the palm oil in the vitamin E I used.

s&s
Title: Re: Careful
Post by: Hawk on June 10, 2009, 09:33:49 AM
I have never used DMSO as a personal treatment of any kind but I have used it as veterinary treatments on animals so I am pretty familiar with it.

For starters, applying a layer of DMSO first will never work because DMSO is absorbed almost on contact.  You can watch a drop of DMSO disappear.  In fact you can taste DMSO within seconds of getting it on your hand.  This indicates to me that it must move through vessel walls quickly.

Next, molecular weight IS EVERYTHING  with any DMSO solution.  It carries EVERYTHING within a certain molecular weight into the tissue.  This includes toxins, impurities, clothing dye, etc.

It carries NOTHING outside of this specific molecular weight range so mixing those things with DMSO does nothing.

You best know that nothing is getting carried along with the solution you mix (impurities) and you must know how the solution you mix will effect the tissue.

Finally, you have no real control and no research to determine how deep the DMSO solution penetrates before it is carried away from the site.
Title: Re: Careful
Post by: slowandsteady on June 10, 2009, 10:37:23 PM
I have never used DMSO as a personal treatment of any kind but I have used it as veterinary treatments on animals so I am pretty familiar with it.

For starters, applying a layer of DMSO first will never work because DMSO is absorbed almost on contact.  You can watch a drop of DMSO disappear.  In fact you can taste DMSO within seconds of getting it on your hand.  This indicates to me that it must move through vessel walls quickly.
I don't apply it first, but in a mixture. You may have a point that it would best to apply the mix without DMSO first, and after a while the DMSO.
Quote
Next, molecular weight IS EVERYTHING  with any DMSO solution.  It carries EVERYTHING within a certain molecular weight into the tissue.  This includes toxins, impurities, clothing dye, etc.

It carries NOTHING outside of this specific molecular weight range so mixing those things with DMSO does nothing.

You best know that nothing is getting carried along with the solution you mix (impurities) and you must know how the solution you mix will effect the tissue.
I find reassuring that all of my ingredients are vitamins or at least orally safe. I'll watch for irritation.
Quote
Finally, you have no real control and no research to determine how deep the DMSO solution penetrates before it is carried away from the site.
I don't need it to go far, just into the tunica albuginea. It's a fibrous envelope (http://en.wikipedia.org/wiki/Tunica_albuginea_(penis)), it's connective tissue, and so doesn't have a lot of circulation. That's why I'm hoping the topical route will be beneficial.

s&s
Title: Re: DMSO and DMSO based Solutions
Post by: slowandsteady on June 11, 2009, 06:42:44 PM
"Nattokinase is a relatively small size protein with molecular weight of 27.7 kDa [13]. The protein radius, calculated to be 21 Å".

Hawk, do you know what range of particle sizes DMSO works best with?

s&s
Title: Re: DMSO and DMSO based Solutions
Post by: young25 on June 14, 2009, 06:30:48 PM
I too am interested in DMSO, slowandsteady let me know if you see a positive effect, I may also try it sooner than later.

Title: Re: iodine
Post by: slowandsteady on June 18, 2009, 09:36:46 AM
Hint of the day: While SSKI has been recommended for topical application with DMSO, Lugol's solution is not. Lugol's has molecular iodine in addition to KI and will cause irritation when used with DMSO.
Title: Re: Slowandsteady
Post by: Hawk on June 19, 2009, 12:20:57 AM
I am sorry.  I used to know the molecular weight of transport but I am not sure now since it has been a while since I even thought about it.  You may find some info on this site.  It may be somewhere on this site however. http://www.dmso.org/articles/information/herschler.htm
Title: Re: molecular weights for DMSO transport
Post by: slowandsteady on June 19, 2009, 07:17:18 PM
Thanks Hawk, that link was very helpful.

So, from that source we read that "[n]onionized molecules of low molecular wight are transported through the skin with DMSO". I was a little surprised that weight was mentioned instead of molecule size.

One substance that has been tested with DMSO for transport across the skin is morphine sulfate, which has a molecular weight of  668.76 (Da, presumably). Insulin is noted to be too big for passage at 5808 Da. Nattokinase is almost 5 times bigger than that; that's obviously not going to work.

Items in blue should be light enough to work well with DMSO. Items in red look to be too heavy. It looks like enzymes tend to be heavier molecules.

Molecular weights of popular anti-Peyronies Disease supplements
vitamin A = 286.46 Da
vitamin D = 396.65 Da
vitamin E = 430.72 Da (alpha tocopherol)
vitamin E = 416.68 Da (gamma tocopherol)
vitamin K2-MK4 = 444.65 Da
vitamin K2-MK7 = 649 Da (note how the additional sidechains increase the weight)
niacinamide = 122.12 Da
PABA = 137.1 Da
Acetyl-L-Carnitine HCl = 239.70 Da
magnesium ascorbate (vitamin c) = 374.55
rutin = 610.53 Da
astragaloside IV = 784.97 Da
horse chestnut extract = 1131.26 Da
bromelain = 22500 Da
papain = 23000 Da
serrapeptase ~= 60000 Da

A couple of nice findings from the paper Hawk linked:
Quote
The authors recorded that topical DMSO in man exerted a significant effect on the pathological deposition of collagen in human postirradiation subcutaneous fibrosis but did not appear to change the equilibrium of collagen metabolism in normal tissue.

and:
Quote
Berliner and Ruhmann7 found that DMSO inhibited fibroblastic proliferation in vitro.

My first recipe contains the first ingredients through niacinamide (except for the K2-MK7).

s&s
Title: Re: DMSO and DMSO based Solutions
Post by: ocelot556 on June 19, 2009, 07:24:40 PM
DMSO is used in Russia as a treatment for arthritis and related inflammations, I remember reading that somewhere. I used DMSO on my plaque during the first acute inflammatory phase of my disease. It worked well. Only Pentox had a better effect on the pain, which I had to wait a year to get an Rx for.
Title: Re: DMSO and DMSO based Solutions
Post by: slowandsteady on June 20, 2009, 10:55:01 PM
Transresveratrol also has a low molecular weight of 228.24 Da, which might be great for localized application. Apparently transdermal resveratrol (with DMSO) doesn't result in a particularly high peak blood levels, for which the oral route works better.
Title: Re: DMSO and DMSO based Solutions
Post by: slowandsteady on June 20, 2009, 11:26:03 PM
EGCG (http://en.wikipedia.org/wiki/Egcg), Epigallocatechin gallate, aka green tea extract. Molecular Weight: 458.4. Good, another antifibrotic with a low molecular weight.
Title: Re: DMSO and DMSO based Solutions
Post by: newguy on July 15, 2009, 01:19:22 AM
Transresveratrol also has a low molecular weight of 228.24 Da, which might be great for localized application. Apparently transdermal resveratrol (with DMSO) doesn't result in a particularly high peak blood levels, for which the oral route works better.

Out of curiosity did you ever try resveratrol with DMSO?

I saw a report or two on imminst.org relating to a person rubbing  resveratrol into his gums, and in improved their condition (they had been receding). Of course it's entirely anecdotal and not relating to our condition, but it got me to thinking that using it to target peyronie's in a more direct manner, could be useful.
Title: Re: DMSO and DMSO based Solutions
Post by: ocelot556 on July 16, 2009, 10:18:12 PM
I was thinking the other day, I received a topical cream a year ago from my uro, which was ALC mixed with EDTA, a chelating agent. I couldn't use it for the year I was asked to, because it cost 100 dollars a month and was far from covered by insurance. I simply don't have the money, but I usually keep a month's supply around to use when I get flareups.

I was wondering if EDTA would pass through the skin via DMSO. If it could, that has to then be a viable treatment for people who are developing calcification, as EDTA should help chelate them.

I'm glad people are spitballing about DMSO again. I had a good experience dealing with the pain of my initial Peyronies Disease with it - but haven't really continued use, given my relocation to a much shabbier "college-style" house (too dirty to consider using a transdermal agent, can't keep things sterile enough for my cautious nature).

EDIT: I just looked it up, and it says the molecular weight of EDTA is 292.2. Since I have heard some dicussion about circumin on other topics, I decided to look up it's molar weight - it's 368.69. It looks like these are both transportable through the skin via DMSO, if the numbers in the posts below are accurate.
Title: Re: alt-711
Post by: slowandsteady on July 30, 2009, 09:39:47 PM
Alagebrium (ALT-711) also has a low molecular weight of 267.77. Alagebrium has "reversed the upregulation of collagen type I and type III" in the hearts of dogs in this study (http://ajpheart.physiology.org/cgi/content/full/285/6/H2587?maxtoshow=&HITS=10&hits=10&RESULTFORMAT=&fulltext=Millar&searchid=1104955809712_1504&stored_search=&FIRSTINDEX=0&volume=285&issue=6&journalcode=ajpheart). These are the two types of collagen that are the most overactive in Peyronies Disease.

newguy, I haven't tried t-res specifically with DMSO. I might try alt-711 first and report back.
Title: Re: DMSO and DMSO based Solutions
Post by: ocelot556 on July 31, 2009, 07:07:48 PM
Now that's a thought. I know there's been speculation that Alagebrium would be too systemic to have a targeted effect on Peyronies Disease. If you could form a mixture of it and DMSO, you could administer the AGE breaker right to the appropriate AGE crosslinks!
Title: Re: DMSO and DMSO based Solutions
Post by: slowandsteady on August 01, 2009, 11:21:23 AM
If you could form a mixture of it and DMSO, you could administer the AGE breaker right to the appropriate AGE crosslinks!
I'm on day 2 of my trial. I'll update on how it's going. DMSO by itself has been known to soften collagen, and I think my curcumin regime has been quite effective.
Title: Re: DMSO and DMSO based Solutions
Post by: ocelot556 on August 01, 2009, 01:29:33 PM
Are you taking curcumin orally, as well, or just administering it topically?
Title: Re: DMSO and DMSO based Solutions
Post by: slowandsteady on August 01, 2009, 01:46:18 PM
Are you taking curcumin orally, as well, or just administering it topically?
Just orally; 2 g mixed into olive oil, and I've started taking it on waking and after supper. Its molecular weight is 368.39, so it would be a candidate. There would be the color issue to contend with. Better let the wife know first. ;)
Title: Re: DMSO and DMSO based Solutions
Post by: TheSolution on August 04, 2009, 04:33:13 PM
I wanted to reply about DMSO and its inflammatory properties. I have been in the acute phase for 8 months now with pain 24/7. Within 6 days of using 70% DMSO, my pain went away for 1 week. Then is come back after sex. It then went away again within 2 weeks. Now its back again after "her being on top" sex. So sex it out for awhile, but I am confident I can get rid of the pain now.

I am not sure of the plaque removing properties, but the science behind DMSO is irrefutable about its pain relieving ability. I was recommended this 5 yrs ago for shoulder pain by my Chemistry professor. DMSO was huge in the 60' and 70's for immediate pain relief. Even the Chemistry secretary used it for migraines back then. In was sold everywhere back then. It does work. There are a ton of research papers showing its pain relieving abilities. The FDA banned it because of drug use. It become the method for junkies to ingest drugs. Only one women has been linked to a death from DMSO. Which means its ultra safe since Vioxx killed thousands. Go look up deaths from NAID'S, DMSO is safer in my opinion.

None of the studies show any health problems with it. So there is real science behind its safety and effectiveness for local pain relief. Now as a treatment or cure for this problem, only time will tell. But I am so thankful that the pain is getting under control and I can function during the day without obsessing about my penile pain 24/7.

I was using the 70% DMSO in liquid form. I am about to the try the thacker formula. I did spell some of the 99% DMSO on my hand, it burned. Do not apply that directly, its way too strong. Do not wash this stuff off with soap. It could suck the soap in. Wash it with water if you need to. I take a shower afterwards with water only or just let it evaporate.  No soap or shampoo.

It would be good if any others are getting pain relief to post that. I was taking 16 advil a day with no results. I took celebrex and had a bad skin reaction that really hurt. Vicodin did nothing. Demoral made me wacko. This seems safer to me than all of them.   

I also never let it touch my penis head or scrotum, that seems to burn slightly. I guess they are too senstive for this. If I have some discomfort after using, I apply castor oil afterwards. I will modify that by using the thacker formula straight away.

I have been using this for 1.5 months now. 






 
Title: DMSO - the "magic bullet"
Post by: j on August 04, 2009, 05:28:13 PM
Hoo boy. Where to begin...
Title: Re: DMSO and DMSO based Solutions
Post by: MUSICMAN on August 04, 2009, 08:10:56 PM
Yes my pain went away too. (not by using a DMSO solution) The pain was replaced with plaque and most of you know what that did to the angle of the dangle. I do think not having real sex (not natural erections) might lessen the inflammation for some of us.
Title: Re: DMSO and DMSO based Solutions
Post by: newguy on August 04, 2009, 08:45:10 PM
I haven't explored this area yet, though I am of course aware of the risks as well as potential benefits. Does this look like an appropriate product choice:  http://www.phhealth.co.uk/content/dmso-gel
Title: Re: DMSO and DMSO based Solutions
Post by: TheSolution on August 05, 2009, 04:03:25 AM
I did mix a batch of 70% DMSO (99%), 20% Apple Vinegar and 10% Castor oil. The mixture got hot and that surprised me. I have a BioChem background and an exothermic reaction means that something in the mix did react. I looked it up, DMSO reacts with Acetic acid (vinegar) to form acetic anhydride. Normally needs a catalyst to really go, but at this DMSO concentration, does not.
The problem is that acetic anhydride is a known skin irritant and the fumes are harmful to the lungs. Its not a 100% reaction and maybe really weak, but it does present a new chemical into the equation. It does burn as I tried some on my hand. My other 70% DMSO with Aloe does not burn. The vinegar on its own does not burn either. Something is an irritant in it. I am not saying it can't work or is even dangerous, but be careful. Vinegar is normally forming anhydrides on its own in the bottle, but its a slow reaction and safe, DMSO is speeding that up. The strong heat is proof. My bottle went to 110 F from room temp after mixing.

Hopefully I did have real DMSO and real apple vinegar and not some bogus stuff. Anyone else see the heat on mixing?

So for now I am staying with my 70% DMSO that is 70% DMSO, 30% Aloe. This is at least reducing the pain for me.  I do not have plaques, my bend is from forming scar tissue and is getting worse lately from too much sex, which I obviously need to stop for now. But nothing is hard like plaque, so my interest was for pain and its working. It really does work for pain. Within 20 minutes, the pain is reduced by 50% or more. I am using Castor oil or Vitamin E to stop any burning if I get some on other parts that are more sensitive and to soften the skin.
 





 

Title: Re: DMSO and DMSO based Solutions
Post by: newguy on August 05, 2009, 09:37:26 PM
thesolution - the ingredients of the solution in the link I posted are as follows:

Dimethyl sulfoxide 70% (700 mg/mL) deionized water, carbopol, sodium carbonate.


Do you think this would be suitable for use?
Title: DMSO visited again
Post by: Angus on August 05, 2009, 09:53:20 PM

   It seems every 2 or 3 years DMSO becomes an active topic again after lying fallow for a while. I suppose Thackers will always be intriguing and hold interest. I'm not going to go on a Thackers rant, but I will suggest to you guys to be careful with this stuff and the concoctions. You don't have to post in defense of DMSO... I'm just saying be careful with home brews.
Title: Re: DMSO and DMSO based Solutions
Post by: Iceman on August 06, 2009, 02:02:09 AM
i tried DMSO for 6 months - waste of time and money and laundry - i reckon the VED is helping me at the moment - i was off it for 2 months due to housing issues and convenience , i mean its a bit hard walking around with a ved - sneaking into the bathroom etc for 20 mins each night - very suss...... but now im back at home im into the swing of it and routine and found its a big help - my dick was starting to look like the hunchback of notre dame and now it seems to be filling out more and getting back length
Title: Re: DMSO visited again
Post by: slowandsteady on August 06, 2009, 03:55:38 PM
I suppose Thackers will always be intriguing and hold interest.

There seems to have been more heat than light in the discussion a few years back. I try to stick to the science.

s&s
Title: Re: DMSO and DMSO based Solutions
Post by: ocelot556 on August 06, 2009, 03:59:45 PM
In this case, Angus, I think it's more about using DMSO as a transdermal tool (as opposed to a direct injection of whatever it is we're trying to get directly into the plaque) than about some mythical formula made by a small town doctor's grandfather who never thought to tell anyone but a secretive poster who for some reason was the only one exclusively allowed to contact that doctor.
Title: Re: DMSO and DMSO based Solutions
Post by: newguy on August 06, 2009, 04:42:51 PM
slowandsteady - How are your DMSO experiences going thus far?
Title: Re: DMSO and DMSO based Solutions
Post by: slowandsteady on August 06, 2009, 05:03:34 PM
slowandsteady - How are your DMSO experiences going thus far?

I don't use it regularly. When I do, I only use it for transport across the skin: I've tried using a few things like resveratrol, vitamins AEKD, alt-711, niacinimide, and taurine. I've only considered it as a secondary treatment after oral supplements. Nothing groundbreaking to report, but what I'm doing is miles away from a controlled trial. Thanks to Hawk for pointing out that it only works with certain sized molecules; too bad nattokinase is so big.
Title: DMSO Reactions
Post by: TheSolution on August 08, 2009, 12:50:06 AM
It appears that DMSO can turn carboxylic acids which are common in our foods and natural products into esters. Both castor oil (ricinoleic acid) and acetic acid are carboxylic acids or have some content. This reaction is weak and not complete. This reaction is reversed upon entering water where it breaks down rapidly into the original stuff. Esters are not really bad, they are actually strong smelling things like fragrances, the smell of an apple etc...

The problem is that the acetic acid (vinegar) ester is not a nice one. Its a very corrosive substance. I pulled the MSDS sheet for it.
Its called acetic anhydride and its a mirror image of itself and gets the anhydride label.

I think the castor oil is good and I have used it with dmso. I would caution against throwing any oil stuff in dmso as certain things will really react and its very difficult to know what. Anything with a O=C-OH bond is going to react. Take a look at the molecule online and you can get an idea. But this is really difficult science and its over my head now. Too many years gone by. Maybe an active chemist is here who can help. I might be wrong here. Just reading the Chemistry book and seeing a very exothermic reaction here. No other explanation I can think of.

For those who have used it or using it. I would not freak out at all. If it works, then thats your call. These sheets cover every possible affect. It looks like swallowing, breathing it and getting in the eye are the major problems. So be careful. This makes sense. Upon entering water, it will break down and grab a hydrogen atom and leave OH-. Thats lye and very corrosive. But in the blood stream, that OH- is neutralized by the body quickly. The problem I see is the skin is dried out quickly and can be damaged by it. Maybe the castor oil is stopping that problem. I would make sure to clean it with water on it afterwards to rehydrate the skin and make sure the base OH- is gone. After entering water though, the acetic acid is back and now in the bloodstream as intended. The mutagenic affect or cancer causing affect of Acetic anhydride would certainly be on the lungs and stomach as they don't like basic conditions for long. But its unlikely that this little amount affects the internal pH of the blood and causes that in the body after using. Can't be sure about the penis skin cells. So wash it off afterwards. OH- is corrosive and causes the big C over time on the throat and lungs. Avoid the vapors!

For Acetic Anhydride - MSDS sheet
Inhalation:
Vapors are corrosive to the mucous membranes of the upper respiratory tract. Exposure to vapors may cause irritation of the nose, throat, and coughing. Exposure to high concentrations may result in severe damage to the lungs. Symptoms of lung edema are often delayed and are aggravated by physical effort.
Ingestion:
Corrosive. Causes a burning pain in the stomach, followed by nausea and vomiting.
Skin Contact:
Corrosive: Does not cause severe burning on contact but can cause delayed reaction burns. If not removed by washing, the skin may become reddened and later turn white and wrinkled. Continued skin contact may cause dermatitis.
Eye Contact:
Corrosive: Contact with the liquid or vapor may produce a burning sensation and tearing. Redness, pain and blurred vision may be followed by permanent eye damage. The appearance of eye burns may be delayed. Irritation effects begin with airborne concentrations as low as 0.36 mg/m3.
Chronic Exposure:
Repeated and prolonged exposure to vapor may cause irritation of the skin and chronic eye irritation.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders or eye problems, or impaired respiratory function may be more susceptible to the effects of the substance.
 
Title: DMSO reactions II
Post by: TheSolution on August 08, 2009, 01:02:57 AM
One important fact about these reactions. They are very weak and not complete which is good for us. Normally DMSO is very stable and won't do anything. (In this case, its helping the Vinegar react with itself in the absense of pure water which is normally good for giving H+ to any acids and keeping them stable).
Also certain compounds really speed them up. A salt will throw this reaction to completion. So if you use DMSO, don't just throw anything all together. Salts will really affect these things. Make sure the stuff has no Iodine content  or any metal salt. Its a catalyst and shifts this thing bigtime. I am going to try white vinegar this weekend to see if it reacts as much. Maybe the apple vinegar has too much junk. Pectinase is too big to make it in anyway. Why not use pure vinegar. (diluted of course). I don't understand the apple vinegar other than previous habit. Plus, Pectinase works well at a pH of 4-5. Not 6.5 to 7.5 like our blood.

Enzymes do have working ranges. They can be useless in certain environments and temperatures. Our body enzymes don't work outside of 95-105Deg F. Thats why we die when we our outside that range.


Title: Re: DMSO and DMSO based Solutions
Post by: TheSolution on August 08, 2009, 02:01:52 AM
Newguy,

I am not familiar with Carbopol. On the web it says its acrylic acid crosslinked. Is so, it will never get into the skin as its huge. Not even on the scale of this stuff we are doing. Its a piece of plastic. I must not be looking at the right thing. If its a brand name, please let me know what it is.

The sodium bicarbonate is probably not a good one as its everywhere in the blood already. Carbonate ions are the main way we control pH of the blood. So its already there in the carbonate acid form. H2CO3 or HCO3-. (sodium bicarb is NACO3. So lose the sodium and CO3(2-)grabs some H+ from water.)

Plus, this is a salt and can really do weird things in DMSO and acids. Salts are things with sodium, potassium or calcium at the start of the name. (not 100% accurate, but that will cover the things we are doing). The Na+ leaves and this creates a negative ion that is very reactive and has no H+ to stabilize like in water. So its very reactive stuff. Caroboxylic acids like I described before are far less reactive. Pure negative ions will react and create unknown stuff. Adding lots of water would change this, but then the DMSO would be too dilute.

But this chemistry gets really complicated fast. Normally you do the reaction and then start running checks to see what you got or didn't get. That is the 100% way to know. I lack the testing equipment nowadays to know.

I think if we stick with normal natural stuff and stay away from salts,  its probably much better for you. All these weak acids are going to react to an ester and then want an H+ ion and get it in the blood and be fine. Just don't forget to wash off the stuff with water or castor oil to make sure you get any left over OH- off your direct skin. Maybe better to finish with pure castor oil. The castor oil does seem to really help by itself anyway, so it can't hurt.

(The msds sheet even says it. The skin burns can be delayed. Thats because it leaves OH- behind and thats corrosive stuff. So neutralize it with water or something with an H+ to give like Castor oil. Its not like you have 500 grams of leftover OH-. Its very small, and will be fine with anything other than air or nothing. I am unsure if the castor oil in the mix does this. Better to play it safe.)
 

Title: Re: DMSO and DMSO based Solutions
Post by: newguy on August 16, 2009, 09:15:21 PM
Thanks for the detailed posts TheSolution. I might try DMSO it on its own for a while and see what results I get. Do you have a good / reliable source for DMSO? I'm in the UK and unsure of where to purchase it from. It doesn't sound like the kind of thing that any changes should be taken with in terms of impurity and whatnot.
Title: The 1000 post archive
Post by: newguy on September 02, 2009, 09:54:49 PM
I took the time to read through the archive and some of the posts there do appear to suggest that Thackers Formula was useful for some individuals. However, nowadays the attitude towards these treatments isn't really all that positive. In part I assume this is because if not followed correctly (and possibly even if it is) DMSO treatments are risky. This also explains why at least in many countries they are not really explored all that much. There must be more to it than that though. Is there the feeling that some of the replies back then are dishonest or inacurate? It's hard for me to get a full understanding and appreciation of the flow of conversation back then.
Title: Re: DMSO and DMSO based Solutions
Post by: ocelot556 on September 03, 2009, 11:46:05 AM
Yes, newguy, I agree with you on the flow of the conversation.

I have trouble believing that there was a guy who's father was a small-town doctor who found a home remedy for an as of yet incurable condition, was the only person to have ever reached this conclusion and never conferred with another doctor or included the medical community in this find.

I have trouble believing the he gave the solution to his son, another physician with no desire to advance the medical community in any way, short of having furtive meetings with a single member of this forum, because the son was too thin-skinned to tolerate people doubting the solution's efficacy.

I'm surprised this got so much play on the forum. It just seems so... disingenuous. I'll admit to considering giving it a shot, sort of - instead I bought a DMSO/aloe solution that DID help me with my acute bouts of pain. But as soon as I found a better alternative (Pentox) I discontinued use.
Title: Re: DMSO and DMSO based Solutions
Post by: slowandsteady on September 03, 2009, 06:17:17 PM
DMSO is used in plastic surgery (PMID 19338814). Apparently it can temporarily increase tissue elasticity. I wonder if it might help those using traction. (I don't see myself using traction; just a thought I had).

s&s
Title: Re: DMSO and DMSO based Solutions
Post by: newguy on September 03, 2009, 08:05:05 PM

s&s -  In scleroderma patients I believe that it was found to return some elasticity too. Are there many refernences to DMSO and elasticity around? DMSO Studies have been very limited, so it's hard to tell how much it really helps. Some people here have suggested that it's useful at pain relief though, so I'm going to try it out. Also my Low Dose Naltrexone should be here in a couple of weeks. Interesting times.
Title: Re: DMSO and DMSO based Solutions
Post by: newguy on September 07, 2009, 12:33:58 AM
Quote
Combined nonlinear imaging technique reveals interaction of chemical agent with dermal collagen

Some chemical agents, including dimethyl-sulfoxide (DMSO), induce temporary transparency of the skin. This process, known as skin optical clearing, provides a direct solution for a problem well known to dermatologists: a limited view of what lies underneath the skin's upper layer. By making the skin's upper layer temporarily transparent, application of DMSO can thus aid the diagnosis of skin conditions.

Despite its usefulness, the actual mechanism of DMSO induced skin clearing is not understood. This lack of understanding also limits the application of the skin clearing method. It is, therefore, important to find out what the interactions are between DMSO and skin components that underlie the observed optical clearing effect. Experiments in vitro have suggested that the interaction of DMSO with collagen may play an important role in the clearing process. To confirm this hypothesis, BLI LAMMP researchers have now performed accurate experiments in skin in situ.

Laser scanning microscope system on which the experiments were performed. Measuring both the local concentration of the clearing agent and the dermal collagen in intact skin samples is not trivial. Students Max Zimmerley and Anthony McClure, in a joint project with LAMMP principal investigators Bernard Choi and Eric Potma, accomplished such measurements by combining second harmonic generation (SHG) microscopy with coherent anti-Stokes Raman scattering (CARS) imaging. Whereas SHG exhibits excellent sensitivity to collagen, CARS allows a sensitive registration of the local DMSO concentration.

By performing careful measurements, the research team managed to determine the overall decrease of fibrous collagen as a function of DMSO concentration in the human dermis. When a correlation with the skin's light scattering properties was made, the measurements revealed a likely correlation between skin optical clearing and the DMSO induced changes to the fibrous collagen matrix.


The results of this study, which are published in the April issue of Applied Optics, provide an important step to a comprehensive understanding of the skin optical clearing process. Future studies will focus on the reversibility of this process and on establishing clear benchmarks for the clinical applicability of DMSO as an optical clearing agent.

For more information please contact
Bernard Choi (choib@uci.edu)
Eric Potma (epotma@uci.edu)
- http://www.bli.uci.edu/news/news.php?id=dmso

It related to the skin, but due to the nature of DMSO, it's not entirely unlikely that it relates to areas beneath the skin too. An interesting and recent finding on a site about lasers, of all places. DMSO possibly compromises the structure of collagen fibers. To what extent it specifically targets overproduction of collagen , if it does at all, is something that would be interesting to know. If I find any interesting studies in relation to that I'll post them.

Further reading: http://choi.bli.uci.edu/pdfs/LSM_2009_41_142.pdf  cites the above findings.
Title: Re: DMSO or DMSO-Aloe Vera
Post by: young25 on September 08, 2009, 08:46:28 AM
Which is a better DMSO product to be bought? Only DMSO or DMSO with Aloe Vera? I am providing the link to both the products, can anybody help me with which is better. Thanks


http://www.vitacost.com/DMSO-Unfragranced-Gel-4-oz?csrc=GPF-606746111422

http://www.vitacost.com/DMSO-Gel-with-Aloe-Vera?csrc=GPF-606746111835
Title: Re: DMSO or DMSO-Aloe Vera
Post by: slowandsteady on September 08, 2009, 09:51:23 AM
Which is a better DMSO product to be bought? Only DMSO or DMSO with Aloe Vera?

I would not get DMSO with aloe vera. DMSO transports low molecular weight molecules through the skin.

"Cytotoxicity of a low molecular weight fraction from Aloe vera (Aloe barbadensis Miller) gel" (PMID 9403965 (http://pubmed.gov/9403965)):
Quote
The toxic activity of LMWF [low mol. wt fraction] was compared to that of sodium dodecyl sulfate (a well-known toxic substance), aloe-emodin and aloin (an anthraquinone and its precursor present in Aloe vera cortex) using the chemilumescence assay, and was found to be of similar potency to these toxic substances on a weight-to-weight basis. These results confirm that Aloe vera gel contains toxic low mol. wt compounds, and every effort must be made to limit the amount of these toxins in the commercially prepared Aloe vera gel products.

s&s
Title: Re: DMSO and DMSO based Solutions
Post by: young25 on September 08, 2009, 11:06:51 AM
Thanks S&S, I will go with only DMSO then. Also did you find any benefit of DMSO on erections?
Title: Re: DMSO and DMSO based Solutions
Post by: slowandsteady on September 08, 2009, 11:59:57 AM
No, but then I don't use it everyday so I haven't given it a fair shot.

s&s
Title: Re: DMSO and DMSO based Solutions
Post by: TheSolution on September 29, 2009, 03:00:15 AM
After trying the different formulas, I can not find anyway to make the DMSO not burn unless I just buy the premixed aloe formula. For me, this is pretty benign and helpful for pain. I don't believe it has any affect on bend, but sometimes its nice to reduce pain.

But I am not using right now as I have found that ALC and my spa are helping more. The hyperthemia is doing more for my pain than anything. I am also using hyperbaric chamber and HGH. Pain is way down. I will write about those in another forum.
Title: Re: DMSO and DMSO based Solutions
Post by: young25 on September 30, 2009, 09:54:04 AM
most of the people who were part of initial set who were using DMSO are not posting now in the forum.. Is it something to do with them getting better as very few people getting better share their stories? My DMSO is on its way so was just going through the whole thread. Anybody in touch with avid DMSO user..
Title: TOPICAL Treatments
Post by: slowandsteady on October 23, 2009, 05:15:23 PM
Taurine can be available to the tissues topically according to PMID 18438702 (http://www.ncbi.nlm.nih.gov/pubmed/18438702).
Title: Re: DMSO and DMSO based Solutions
Post by: gerMike on November 09, 2009, 07:57:00 PM
I would say, IF they saw the slightest improvement then they would post it here. I definitely would.
Title: Re: DMSO and DMSO based Solutions
Post by: Blade on November 09, 2009, 08:30:38 PM
I agree they may have seen improvement and just don't report it. When I do see improvement I'll want everyone to know. These curves and bends are Royal pains.
Title: Re: DMSO and DMSO based Solutions
Post by: Glowingstorm on November 30, 2009, 05:11:25 PM
Simple Question....

What are my options for obtaining pure Pharma grade DMSO or near-Pharma grade DMSO (ie. veteranarian  grade)

Can it be bought from overseas???
Are there legal loopholes to obtain it in the states...???
Is the DMSO found in hardware stores really that bad????

What grade of DMSO do **YOU** use???

If you can answer all or any of these questions..., it'd be appreciated, thanx!!!! :)


PS: can i get pharma grade DMSO from a naturalogist?? or a homeopathic doctor (whatever the term is...) thanx again
Title: Re: DMSO and DMSO based Solutions
Post by: slowandsteady on November 30, 2009, 06:31:27 PM
You can get DMSO on amazon. I don't know what grade level it is.
Title: Re: DMSO and DMSO based Solutions
Post by: Glowingstorm on December 06, 2009, 01:29:46 PM
Fortunately I've answered alot of my own questions that i posted as of recent. My next question is how do you determine the mixing ratio of DMSO to another chemical... such as "X" # of mL for every "X" # of milligrams?
Title: Re: DMSO and DMSO based Solutions
Post by: Blade on February 06, 2010, 09:03:30 PM
I'm an American overseas and I ordered my DMSO 99.9% from the USA. I ordered from Jacob,s Lab and had it delivered to a friend and he brought it over. Could not taste the garlic that's some say comes with it when applied. Please read the posts here on handling. Be careful out there!
Title: Re: DMSO and DMSO based Solutions
Post by: Tim468 on February 07, 2010, 11:45:28 AM
Dear Glowingstorm,

First attempt to post got eaten up (not sure how).

Whenever a first few posts by a newcomer here are on a treatment that is not first line, I worry a little bit. There are other, better treatments than DMSO. Read up here to see what we are all trying out - you will not find many (any?) success stories with DMSO.

That said, yes, non-medical grade DMSO IS "that bad". Remember that it transports small molecules in it into you. Any small molecules it seems. Non medical grade DMSO may include solvents and other possibly carcinogenic substances. I would think very long and hard about that.

Tim
Title: best topical oil/lubricant for a healthy looking penis?
Post by: chefcasey on January 17, 2011, 11:20:18 PM
I'm just about running out of my vit. e coco butter oil that I've been using for masturbation/ved lubrication.  Just wondering if there was a consensus on what works best to make the veins and skin look healthiest?  I've been reading on these "essential vein oils" that people rave about, but apparently you have to make it yourself.  I'm just looking for something to buy at the store.

perhaps something that works as a good ved lubricant too?
Title: Topical Minoxidil
Post by: GS on January 18, 2011, 09:31:07 AM
"The mechanism by which minoxidil promotes hair growth is not fully understood. Minoxidil is a potassium channel opener, causing hyperpolarization of cell membranes  Minoxidil is also a vasodilator. It is speculated that by widening blood vessels and opening potassium channels, it allows more oxygen bugs, blood and nutrients to the follicle."

If topical minoxidil increases blood flow to hair follicles, is there any efficacy to using it to increase blood flow to one's penis?

This makes sense to me and I would like to see our member's thoughts.  Particularly, could it do harm?

GS
Title: Re: Topical Minoxidil
Post by: slowandsteady on January 18, 2011, 03:35:00 PM
On the plus side, minoxidil is a small molecule (209 daltons), so it could have good transdermal penetration. It looks like hopes that minoxidil would be effective as an anti-fibrotic didn't quite pan out (http://www.ncbi.nlm.nih.gov/pubmed/15908192).
Title: Re: Topical Minoxidil
Post by: GS on January 18, 2011, 04:14:27 PM
While doing more on line research on minoxidil, I have read several stories about it causing sexual side effects.  So, even if it is good for blood flow, it may not be a good thing for our penises.  I will continue to research and see what I find.

GS
Title: Thoughts on Thacker's Formula ...
Post by: George999 on February 23, 2011, 12:57:02 AM
Its been years since Thacker's Formula has been discussed on this forum.  Interestingly, tonight, on the Doctor Oz show the point was made that major anti-inflammatory properties are being attributed to TOPICAL CASTOR OIL, a major component of Thacker's Formula.  The recommendation is to use topical Castor Oil with heat as a topical anti-inflammatory treatment.  Is this interesting or is this interesting?  - George
Title: Re: Thoughts on Thacker's Formula ...
Post by: BentYoung on February 23, 2011, 01:23:13 AM
George -

This is interesting. I have personally used castor oil along with a heating pad for several months. I found that the external skin felt smoother and more elastic, but the internal scarring remained unchanged. This seems like a logical treatment, but I wish the oil had more penetrative qualities.
Title: Re: Thoughts on Thacker's Formula ...
Post by: George999 on February 23, 2011, 11:00:18 AM
Perhaps that is the role the DMSO plays.  But perhaps also it is actually the castor oil that is the major anti-inflammatory agent and not the DMSO itself.
Title: Re: Thoughts on Thacker's Formula ...
Post by: rd on February 23, 2011, 11:50:52 AM
Has anyone had any success with the thackers formula? Also can you refresh what it is. I looked around and started to look through the long thread on here about it but am not sure what or how you apply it.
Title: Re: Thoughts on Thacker's Formula ...
Post by: qowpel on March 02, 2011, 06:37:21 PM
I figure WHY NOT. I might as well use the stuff you know? Even if it takes forever to see results or a bit of improvement while using it.

The problem is, well, how the heck do you mix it?

Because you can watch a drop of dsmo evaporate if it hits a surface, well at least the skin. And castor oil is VERY thick guys. So how would one evenly mix castor oil, which is thick, apple cider vinegar, which is very thin, and dmso? Because what I have been doing is applying the castor oil to the guaze first. Then the apple cider vinegar. I throw the gauze on after applying those two, and thenwrap it around the penis and then put a buncha dmso on top of it as it soaks through.....

But I have heard of others using this, would take a glass bowl or something, and mixing the ingredients in that bowl, and then soaking the gauze in the mixture, rather than the method I have listed above..... Thoughts?  By the way, It is 10% castor oil, 20% apple cider vinegar, and then 70% dmso
Title: Re: Thoughts on Thacker's Formula ...
Post by: rd on March 14, 2011, 08:56:53 AM
Anyone have any news to report on this. I've recently added this to my plan, and do notice some tingling/itching in the area of the plaque/lump when applied.
Title: Re: Thoughts on Thacker's Formula ...
Post by: Nemo on March 15, 2011, 02:49:00 AM
Years ago when I tried Thacker's, I remember itching and even skin irritation all along the penis.  It wasn't unbearable.  The only thing Thacker's did for me (and I think I tried it about six months or more, maybe close to a year) was it seemed to improve my erections.  Not sure what to attribute this to.  Didn't do anything to reduce scar tissue though, not that I could tell.

Nemo
Title: Anybody ever tried Topical Contractubex (used for Dupuytren's)?
Post by: Luciano on April 14, 2011, 03:50:00 PM
Here in europe some urologists prescribe a topical gel called Contractubex for Peyronies Disease. It is supposed to help with Dupuytren's contracture. And as I understand Dupuytren's contracture is related to Peyronies Disease. (xiaflex is also used for Dupuytren's).

Quote
Drug name: Contractubex

Active substance: allantoin, heparin sodium and onion extract

Pharmacological effects: Contractubex contains a combination of onion extract, allantoin and heparin sodium. Contractubex exerts fibrinolytic, anti-inflammatory, anti-thrombotic and keratolytic action. Contractubex stimulates cells regeneration and inhibits the proliferation of fibroblasts.

Indications: Contractubex is approved for the treatment of the following conditions:

    * Hypertrophic and cheloid scars that occur after surgical interventions, amputations, burns and traumas
    * Stiff joints
    * Dupuytren's contracture
    * Traumatic tendinous contraction
    * Atrophic scars
    * Acne and shingles (chicken pox) scars
    * Scars following ulceration and acid burns.
    * Biopsy & Breast amputation scars.

Warnings and Precautions: Contractubex should not be used in the following conditions:

    * Hypersensitivity to any components of the preparations.
    * Having light therapy (called phototherapy) for your skin condition

Contractubex should be used with caution in pregnancy, breastfeeding and children
Do not cover the area being treated with bandages, dressings, or wraps.

Contractubex side effects: Drugs may cause side effects which in specific patients may manifest differently. In the following paragraph we want to underline the most serious and frequent side effect of Contractubex  that  were identified by the drug manufacturers. The possibility of the adverse effect manifestation depends only on the individual and his specific traits.

    * In rare cases Contractubex  side effects include: local skin reactions such as rash, hives, redness, burning, dry skin

For full information on any risks and adverse effects associated with Contractubex, please consult your doctor, read the included leaflet or contact our customer support service.



As 100g tube costs  33 € (about 50$) I'm going to try it. (It does not require prescription)
I realize that there is no point applying it everywhere, but I have a visible scar just beneath the gland going half around it, I will try it there. I will post results if any, but my pharmacist said it will take time to work. (on normal scars)
L.


More info:
I just found  this post on peyronies.org:
Quote
i have seen a doctor who has suggested pentoxyfylline 400 mg three times day,Beta Sclerobion two times a day.he has alo asked me to apply contractubex gel and fudic cream on the penis several times a day(i can see on the prescription for contractubex gel that it is useful in duptrutren contracture ).i have been on these medicines for four months but there is very little benfit .the tissue is still there .I have read on the net that pentoxifylline trental has to be taken for atleast 6 months to see its full effects.
So I do not put to much hope in it, but for me its worth a try.
(the beta sclerobion if someone wonders is: one capsule contains: Vit C 100 mg, Vit E 25i.u., Selenium 150 mcg Manganese 1.5 mg, Beta Carotene 5 mg, Copper 1 mg, Chromium Picolinate 200 mcg
and the fudic cream is an antibacteria cream)
Title: Re: Anybody ever tried Topical Contractubex (used for Dupuytren's)?
Post by: crashbandit on April 15, 2011, 12:23:05 AM
So a doctor needs to prescibe this stuff? Would an insurance company cover this? Let us know what you think of it after trying it for abit.

Thanks Luciano
Title: Re: Anybody ever tried Topical Contractubex (used for Dupuytren's)?
Post by: Luciano on April 15, 2011, 07:48:30 AM
Well here in europe, depening of your insurance, they will cover anything.
If you only have public healthcare, then there are only certain products that are covered.
If the product is more than $7, You pay like $7 per product and the rest is payed for by insurance.

But if you have a complementary insurance, you still have the basics like above, but if you are in hospital you can have single room, or you can choose a doctor that does not have a contract with public insurance.
In my plan for instance, they also cover up to $3000 a year on all the stuff that a doctor would prescribe me (even if its not covered by public insurance) Main conditions: It must be sold in a pharmacy AND I have to have a prescription for it.
(but I do pay like extra $300 a month for private insurance)
I dont have the teeth option, (another $200), but if I would I can have up to $8000 done by year covered by private insurance. (like 3 or 4 implants or stuff like that... which is not covered by public insurance).

So I guess thats why he got a prescription (allthough what I described above is Austria only, but germany etc.. have similar systems)

L.
Title: Anyone used DMSO to help with Peyronie's Disease?
Post by: quickguide90012 on May 13, 2011, 08:36:13 PM
Has anyone here tried DMSO with peyronie's disease?  I read this was something that can help it.  But i read you have to ask a doctor because its dangerous?  I know you are suppose to apply it to the penis but has anyone tried it?  I see they have this on amazon.  It seems to be a cream that you apply on yourself and it heals but there are some hazards of it.

Title: Re: DMSO and DMSO based Solutions
Post by: quickguide90012 on May 16, 2011, 08:41:10 PM
Anyone here that use DMSO and had it work?
Title: Re: DMSO and DMSO based Solutions
Post by: George999 on May 16, 2011, 09:08:41 PM
Quick,  READ the post immediately prior to your post.  DMSO is NOT totally safe.  There are far better and more effective treatments.  - George
Title: Re: Anyone used DMSO to help with Peyronie's Disease?
Post by: quickguide90012 on May 16, 2011, 09:33:21 PM
anyone?
Title: Re: Thoughts on Thacker's Formula ...
Post by: goodluck on July 22, 2011, 11:14:43 PM
For what it is worth, in Ryan Wellman's book on Peyronies he says Thacker formular or Jonathans wright's version of it is his number one recomended natural therapy. 

From what I hear here it does not seem to yield very good results.

Title: Re: DMSO and DMSO based Solutions
Post by: Pfree on August 04, 2011, 07:33:10 PM
Has anyone else read this article and watched the video by John Parks? I can't post links here, but Google "sexually healthy man peyroine" and you will find it.

He says he had success in treating Peyronie's using a three-phased combination approach of traction, supplements, and topical treatment with DMSO, Potassium Iodide, and vitamin E. He also states that he was in the acute phase.

I agree with the comments below that one should not use industrial grade DMSO. Dr. Jacob's lab (Google "dr jacobs labs") sells high quality DMSO. The transdermal quality of DMSO certainly makes it attractive to try to deliver a catalyst to the plaque.
Title: Re: DMSO and DMSO based Solutions
Post by: goodluck on August 05, 2011, 01:26:06 PM
I just saw Park's introductory video. He claims he is cured. Cured can mean many different things. Not sure if that is 100% back to normal or well enough to have sex without pain.  He uses Vit E and SSKI with the DMSO which is what Dr. Jonathan Wright suggests. 

I once used DMSO for tendonitis about 15 yrs ago.  I recall getting the garlic taste in my mouth within 1 minute after applying it.

I did not use it for long becasue of all the warnings against human use.  I don't recall it doing much to help my issue.  Since I could taste it so quickly there is no doubt in my mind it is a very good carrier.

I will add, in some people SSKI can surpress the thryoid or give an allergic reaction so people should be careful. Gradually increase its use and observe for reactions.

His story is compelling and I will read more on the site.

Title: Re: DMSO and DMSO based Solutions
Post by: goodluck on August 06, 2011, 03:19:19 PM
I spent a little more time on John Parks's site: http://www.sexuallyhealthyman.com/p/peyronies-disease.html

In summary he used a traction device, oral supplements and a topical jell that is DMSO based simultaneously. I know the topic is DMSO based solutions so I will limit this post only to that and create a new thread to summarize his complete protocol.The topical jell is similar to Dr. Wright's formular and is as follows.

70% DMSO gel with alovera.  "Size of a Dime" amount
Topical Vit E - He cuts open one liquid capsule of Vit E and applys it to the penis.  I assume it is 400 iu's as that is a very common value in a gel cap.  He does not state what brand, type or amount of Vit E. Just one capslule.
SSKI- super saturated potasium Iodide. 2 drops.

As a side note Wright's formular is a 50/50 mixtue of DMSO to SSKI.  (IMHO that would be alot of potasium iodide or very very little DMSO)

Parks also says this formular works good on reducing scars.

It does seem this is more convenient to use than  "Thackers Solution" which uses Castor oil/DMSO solution soaked in a flannel cloth and then suggests placing a heating pad over it.

Parks eye balls the amout of DMSO gel. Applys it directly to the penis along with the E and SSKI and massages in. It sounds easy. Not comment on how long to leave it on. However the standard comments about testing the skin for a reaction to the DMSO is there.

He does recommend specific brands of SSKI and DMSO to use and has direct links to purchase them on Amazon. 

Parks states he was cured in about a year of dilligently following this protocol.
Title: Re: DMSO and DMSO based Solutions
Post by: Pfree on August 09, 2011, 06:53:06 PM
Thanks for your thoughts and comments, goodluck.

I researched using Serratiopeptidase (Serrapeptase) combined with DMSO to deliver it. There was a study done (not specifically for Peyronie's, but for successful transdermal application) and it did work with DMSO. This restriction on posting URLs is a bit maddening, but I understand why it's done. If you google "Topical Formulations of Serratiopeptidase: Development and Pharmacodynamic Evaluation" you should find the study on the  NIH web site.

I just started taking the supplements used by Parks. I also mixed 90 percent Jacob's DMSO liquid with the contents of the serrapeptase capsule and applied it to the plaque and surrounding area. I know it's risky, but I'm desperate! I will report on progress (or not) in the coming weeks.

Another thought on DMSO: years ago when I had a very stiff shoulder, a friend gave me some intended for use on animals. It did help, but I noticed the garlic taste almost immediately. With the Dr. Jacob's brand I do not notice any garlic taste.
Title: Re: Anyone used DMSO to help with Peyronie's Disease?
Post by: ChrisFoy on August 13, 2011, 02:47:08 AM
No,Why don't you take advice of your doctor first?
Title: Re: DMSO and DMSO based Solutions
Post by: goodluck on August 14, 2011, 01:38:30 PM
Pfree,

Let us know how it is working for you. 

I know many here don't think too highly of topical applications but that should not keep you from tying.

You have to try some different approaches if nothing is working for you. 

I was unaware about any restrictions on positng URL's . I am sorry if I pi$$ed anyone off.  Thanks for bringing it to my attenion.

Goodluck
Title: Re: DMSO and DMSO based Solutions
Post by: fubar on August 14, 2011, 05:34:39 PM
Brother

Do what you have to do.List resources everything.One of the rules of.this forum is not to use numbers I'm your user name.That he not stopped anybody using numbers.I think the most important thing is to keep things civil and keep curse words to a minimum.

Yeah topical remedys are not very popular it falls into the catagory like shock wave and laser treatment. Basically a rediculous remedy that has no weight.

Fubar
Title: Re: DMSO and DMSO based Solutions
Post by: crashbandit on August 14, 2011, 06:04:55 PM
Thanks for your thoughts and comments, goodluck.

I researched using Serratiopeptidase (Serrapeptase) combined with DMSO to deliver it. There was a study done (not specifically for Peyronie's, but for successful transdermal application) and it did work with DMSO. This restriction on posting URLs is a bit maddening, but I understand why it's done. If you google "Topical Formulations of Serratiopeptidase: Development and Pharmacodynamic Evaluation" you should find the study on the  NIH web site.

I just started taking the supplements used by Parks. I also mixed 90 percent Jacob's DMSO liquid with the contents of the serrapeptase capsule and applied it to the plaque and surrounding area. I know it's risky, but I'm desperate! I will report on progress (or not) in the coming weeks.

Another thought on DMSO: years ago when I had a very stiff shoulder, a friend gave me some intended for use on animals. It did help, but I noticed the garlic taste almost immediately. With the Dr. Jacob's brand I do not notice any garlic taste.

Good luck with that. I think I would want to try something like this before VI injections. DMSO is definitely known for a great carrier deep into the tissues, how far and how exactly it works, I have no idea. How could it hurt though? Could the DMSO cause scarring on the tunica? The last thing you want to do is cause more damage. And without proper guidence from doctors or studies, there is a chance you might cause more damage.

Chances are it won't do anything. And you could fluke out and actually "cure" yourself. Because using DMSO you have a good chance at doing something.  Just make sure you don't use too much and burn yourself or something crazy like that. Go slow and make a solid plan to follow through with. And study each ingredient very throughly before slapping it on your johnson.

Any updates?
Title: Re: Anyone used DMSO to help with Peyronie's Disease?
Post by: crashbandit on August 14, 2011, 06:43:48 PM
It's been awhile since you posted this question. But there's another big thread on DMSO in the ALternative treatments section.

Here's the link:

http://www.peyroniesforum.net/index.php/topic,39.0.html
Title: Re: DMSO and DMSO based Solutions
Post by: fubar on August 14, 2011, 08:02:08 PM
Crash

What if you use dmso as a delivery and add veraprimil cream?

Fubar
Title: Re: DMSO and DMSO based Solutions
Post by: crashbandit on August 14, 2011, 11:42:48 PM
Hey Fubar,

Veraprimil is a vasodilator which is great for opening up the vessels and supplying more oxygen to tissue. The DMSO is awesome for penetrating the skin barrier, which combined with the veraprimil would allow it to do it's magic. DMSO is really good too because it does not damage the tissues... so they say...

It could be worth a try but I just don't know much about it and whether it even has a chance to help peyronies because your dealing with scar tissue. I'd say this kind of a topical could have a chance with an acute case of Peyronies Disease in the beginning stages of inflammation, which is why I'm so intrested in it.
Title: Re: DMSO and DMSO based Solutions
Post by: George999 on August 14, 2011, 11:53:59 PM
The problem I see here is that verapamil *cream* is *not* pure verapamil.  It contains other ingredients *not* intended to penetrate the skin, ingredients that just might be *toxic* if transported trans dermally.  Thus I would be *very* cautious with something like this.  - George
Title: Re: DMSO and DMSO based Solutions
Post by: ComeBacKid on August 15, 2011, 01:13:46 AM
Check out our verapamil study.  Theres no studies showing verapamil even does anything to help peyronies.  As far as I'm concerned its about as good as rubbing butter on your penis.  I think the verapamil debate has been over for a long time.  Pentox does work though.

Comebackid
Title: Re: DMSO and DMSO based Solutions
Post by: Pfree on August 17, 2011, 05:19:56 PM
Thanks for your comments, ComeBacKid, could you please tell me where the verapamil study is located that you mentioned?

On a related note, I went to a second urologist today. The first one was a "high power" urologist on "K" street in Washington, DC, late-thirties, whom I went to in June. He palpated the plaque for a few seconds then grabbed his prescription pad and scribbled quickly while brusquely saying, "Peyronie's Disease, look it up on the internet!" I was taken aback, but I continued to explain I have had some other inflammatory issues recently and I wondered if there was any correlation. "No!" was his answer. Jack a$$. So, urologist number two today was quite different. After examining it, he commented that the plaque was pretty large (it's about 5/8 inch wide and maybe a 3/16 deep or a little more). When I went to the first urologist in June, it was a third that size. So much for being proactive about one's health.

Anyway, he said there can be a connection to other inflammatory disorders. He explained that the scar tissue of dupuytren's contracture is identical to peyronie's when examined under microscope. I don't have dupuytren's contracture, but it is interesting to note. About two weeks before I noticed that beginning of the plaque, I developed a very odd skin rash called pityriasis rosea whose cause is not completely understood. It is a benign auto-immune disorder, and the same week I noticed the plaque I also developed strange swelling in several finger joints. I was diagnosed with sub-clinical hypothyroidism and have since began taking medication. (3 months ago.) I went to a rheumatologist and tests revealed none of the inflammatory markers for arthritis. It all really makes a person wonder if these things are related.

This doctor is conservative in that he does not recommend injections for fear of inciting even more inflammation. So, he prescribed colchicine which is a medication against gout, an anti-inflammatory. Long story short to this posting, I am going to try colchicine and Verapimil and use DMSO with the Verapimil to attempt to penetrate the barrier of the bucks fascia and the tunica albuginea. From the comments I've seen so far, I'm not very persuaded that it will help. I forgot to ask the doctor about using DMSO and mixtures of supplements like serrapeptase. I doubt that he would approve of high quality DMSO since it is not FDA approved. I started the John Park regime a week ago, and it is too early to tell. The plaque does feel a bit smaller, but I won't make a sure statement until I can definitively say so. It seems to change almost day-to-day.

Good luck guys, and let me know your thoughts.
Title: Use of TENS Unit in Treating Peyronie's
Post by: Pfree on August 17, 2011, 05:40:18 PM
Hi,

I have a TENS unit (Transcutaneous electrical nerve stimulation) for pain relief on my shoulder. It works, and I recently tried placing the electrodes on and around the plaque. It is not easy to situate, and I wouldn't want to walk around outside of home with it attached, but it definitely has helped with the pain. I googled this and could not find many entries regarding it's use.

I notice that there is an archived thread about using a TENS unit for www DOT peyroniesforum DOT net FRONTSLASH index.php?topic=26.100 for iontophoresis (using a small electrical charge to deliver medicine transdermally). I don't think the TENS unit is designed for this, not sure, but it would be interesting to try delivering DMSO and medicines using this technique. Does anyone know anything about this?

Thanks,

Pfree
Title: Re: Use of TENS Unit in Treating Peyronie's
Post by: crashbandit on August 17, 2011, 05:54:51 PM
I'll have to admit, you are gutsy.

I don't think you will hear alot of feedback about this, I've been reading the forums for a year now and not once have seen a thread about using TENS on Peyronies Disease. I don't see how using a TENS unit could possible help Peyronies Disease. What are you hoping using the TENS unit could accomplish? Blast the scar tissue into a million pieces so the body could get rid of it and then grow a fresh tunica in its place?
Title: Re: Use of TENS Unit in Treating Peyronie's
Post by: Pfree on August 17, 2011, 07:14:58 PM
Thanks crashbandit. I think I'm more desperate than gutsy.

I've noticed since I've used it that I haven't had the pain so I think it is working in this respect. I'm curious about the effective delivery of transdermal medications and wonder if a TENS unit could facilitate it. I did some more research and found that the iontophoresis unit is direct current and is not the same as the TENS. I don't expect the TENS to blast the plaque to pieces, although I sure wish it would!
Title: Re: DMSO and DMSO based Solutions
Post by: Pfree on August 17, 2011, 07:50:20 PM
George999, you have a very good point about Verapimil and DMSO. I read that the Transdermal Verapamil 15% Gel is a compound, and depending on what the other ingredients are, it might be toxic, or certainly less than optimal. I have a very limited knowledge of chemistry, but my understanding is that molecular weight is a critical factor in determining if DMSO can help effective transdermal application: if the molecular weight is too large, it cannot pass through the skin.
Title: Re: Use of TENS Unit in Treating Peyronie's
Post by: LWillisjr on August 17, 2011, 09:29:36 PM
The TENS unit is designed to provide a low stimulate to the nerve endings in your skin and essentially will mask the pain. It does not take the pain away and I don't see how it could possibly help with with remolding the scar tissue.
Title: Re: DMSO and DMSO based Solutions
Post by: George999 on August 21, 2011, 10:39:22 AM
Quote from: Life Extension
Despite decades of research and thousands of studies attesting to its health-promoting properties, dimethyl sulfoxide (DMSO) remains virtually unknown to the medical professional and the public.

Full Article (http://www.lef.org/magazine/mag2007/jul2007_cover_dmso_01.htm)

Its an old article, but still has significance.  - George
Title: Infiltrations of cortisone
Post by: dioporcolorisolvo on September 22, 2011, 01:25:40 PM
What do you think about infiltrations of cortisone?
What are your experiences?
Title: Re: Infiltrations of cortisone
Post by: George999 on September 22, 2011, 08:14:51 PM
Cortisone has actually been tested on Peyronie's and results were not good for some reason.  It never worked out well.   - George
Title: Re: Infiltrations of cortisone
Post by: Ben on September 23, 2011, 02:33:59 PM
cortisone is a steroid anti inflammatory which also act as a immuno modulator. Every medicals experiences with cortisone failed to improve the condition.
Injecting steroid hormones (testosterone) led to total disaster like necrosis.

I try topical dexamethasone in the inflammatory phase with no effect.
Title: Re: DMSO and DMSO based Solutions
Post by: goodluck on September 23, 2011, 04:47:33 PM
Below is some more interesting info on DMSO from Dr. Shillington who runs the Herbal Remedy Yahoo Group.  There is more on the group for those who have interest in diving deeper. Interesting that he highly recommends against using DMSO that comes in plastic packaging as it will eat through it. Personally I had DMSO in a plasitc roll-on type of packaging for 10 plus years in my closet and did not notice anything to that effect.  That said, it is probally still good advice and you do have to respect its carrying and penetrating abilities.

DMSO

DMSO is Dimethylsulfoxide and is processed from pine trees.  Commercial grade is used as a solvent and works wonderfully that way.  The pharmaceutical grade has been used very successfully with Down Syndrome children, Cancer patients, glaucoma, cataracts, and just about any other ill we humans have mocked up.  It is a catalyst second to none as it has the ability to permeate any cell wall existing, including bone and external eye tissue.  You can put a drop on your big toe and taste it in your mouth in anywhere from 8 to 12 seconds.  Amazing stuff.  One of its greatest characteristics is the ability to take herbal biochemicals with it when it passes through these cell walls.  This gets the 'goodies' where they are needed fast.  It also happens to be a free radical fighter without peer and bonds to free radical hydrogen, oxygen, and carbon atoms and neutralizes them instantly.  Most exciting to me is that it also happens to help realign DNA back to the original blueprint.
 
The above are the main reasons it is in my anti-plague formulation.  There are over 75 different sulfur compounds in Garlic which is a main ingredient in the Total Tonic Formula.  Garlic is "Nature's antibiotic" and used with the DMSO will get in there and knock off bacteria, viruses, and fungi at a tremendous rate.
 
You should be able to get the USP Pharmaceutical Grade at your local drug store or possibly at your local Heathfood store.  If you can't, give me a call or e-mail me privately.  A lot of "healthfood stores" carry a very inferior brand in plastic.  Do not buy this type.  DMSO will eventually dissolve plastic over a long period of time.  The USP Pharmaceutical grade is stored in brown glass with either a teflon or wax top.  This is the variety that is used by the Sierra Clinic to inject into Down Syndrome children to correct that condition.
 
Hope this helps.
 
Love,
 
Doc

Copyright (c) 2001 by Ian 'Doc' Shillington.  All rights reserved.
 
Ian "Doc" Shillington N.D.
727-447-5282
DocShillington@AcademyOfNaturalHealing.com
Title: Re: Infiltrations of cortisone
Post by: crashbandit on September 23, 2011, 08:24:42 PM
I've had great results with diclofenac 10% in plo kit. Diclofenac is an anitinflammatory and it has totally halted my penis pain... Whether it causes more damage then not in the long run is another question. Celebrex worked great too for myself but burnt my stomach up badly, this topical stuff has not done that. I mentioned to the Uro about me using Diclofenac and he didn't say it was bad but didn't really say anything about it either.

I rub alittle of it on my troublesome left side of the penis shaft and it works fast, like 10 minutes. Just make sure to wash it off before intercourse. I'm sure it tastes horrible, not that I had to find that out the hard way  ;D (sorry ladies if you had to read that)

Title: Re: Use of TENS Unit in Treating Peyronie's
Post by: james1947 on February 01, 2012, 11:50:13 PM
Hi Pfree
Your last post regarding TENS was in August. Did you continue with the TENS for your Peyronie's? Have some results you can update the forum?
Thanks
James
Title: Re: Use of TENS Unit in Treating Peyronie's
Post by: Luciano on February 03, 2012, 12:00:25 AM
Well I personnally think the approach is not so bad after all.
I once read a study about ionto (cant find it any more) saying that they had similar results using verapimil plus something and a placebo. vs no treatment at all.
Conclusion: the electric stimulation was more effective than the drug. (although the results were very limited in all cases - something like 7% working out better in the groups having iontophoresis vs 0% in the group having nothing)
So probably (but thats only my idea) the electric stimulation could be  doing something

Luc
Title: DHT gel: experiences.
Post by: dioporcolorisolvo on February 13, 2012, 10:14:05 AM
I wish to begin with application of dht gel.
it's an attempt.

Are there experiences in this forum about that?
Title: Re: DHT gel: experiences.
Post by: GS on February 13, 2012, 10:43:15 AM
I tried it, but didn't give it a chance to do anything.  I thought it was making my hair fall out so I stopped using it.  The hair loss may have been real or imagined, but I got scared and haven't gone back to trying it again.

GS
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: stuartmar on July 15, 2012, 05:53:01 AM
Your last post regarding TENS was in August. Did you continue with the TENS for your Peyronie's? Have some results you can update the forum?
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: stuartmar on July 15, 2012, 05:55:00 AM
You can watch a drop of DMSO disappear.  In fact you can taste DMSO within seconds of getting it on your hand. 
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Pfree on September 10, 2012, 06:38:07 PM
I apologize for not replying sooner. Unfortunately, I stopped using the TENS unit after several weeks, so I can't say with certainty that it made any difference. I am tempted to start again, it is not exactly convenient to setup every day or other day. If I start again, I will definitely post an update.

Pfree
Title: Re: DMSO and DMSO based Solutions
Post by: Hawk on September 12, 2012, 08:44:21 AM
Below is some more interesting info on DMSO from Dr. Shillington who runs the Herbal Remedy Yahoo Group.  That said, it is probally still good advice and you do have to respect its carrying and penetrating abilities.

DMSO is Dimethylsulfoxide and is processed from pine trees.  Commercial grade is used as a solvent and works wonderfully that way.  The pharmaceutical grade has been used very successfully with Down Syndrome children, Cancer patients, glaucoma, cataracts, and just about any other ill we humans have mocked up.  It is a catalyst second to none as it has the ability to permeate any cell wall existing, including bone and external eye tissue.  You can put a drop on your big toe and taste it in your mouth in anywhere from 8 to 12 seconds.  Amazing stuff.  One of its greatest characteristics is the ability to take herbal biochemicals with it when it passes through these cell walls.  This gets t happens to be a free radical fighter without peer and bonds to free radical hydrogen, oxygen, and carbon atoms and neutralizes them instahe 'goodies' where they are needed fast.  It alsontly.  Most exciting to me is that it also happens to help realign DNA back to the original blueprint.
 
The above are the main reasons it is in my anti-plague formulation.
  There are over 75 different sulfur compounds in Garlic which is a main ingredient in the Total Tonic Formula.  Garlic is "Nature's antibiotic" and used with the DMSO will get in there and knock off bacteria, viruses, and fungi at a tremendous rate.
 
You should be able to get the USP Pharmaceutical Grade at your local drug store or possibly at your local Heathfood store.  If you can't, give me a call or e-mail me privately.  A lot of "healthfood stores" carry a very inferior brand in plastic.  Do not buy this type.  DMSO will eventually dissolve plastic over a long period of time.  The USP Pharmaceutical grade is stored in brown glass with either a teflon or wax top.  This is the variety that is used by the Sierra Clinic to inject into Down Syndrome children to correct that condition.
 
DocShillington

I consider the sections of the above quote in italics and underline (by me) to at best have no clinical evidence and at worst to be the babble of a snake oil salesman.

Just as importantly is what it does not say.  DMSO's ability to transport a substance is entirely dependent on the molecular weight of that substance.  It will transport toxins, pollutants, contaminants, dyes, and any other trace particles on the skin or cloth provided they have a low enough molecular weight.  You cannot target where the transported substance goes, how it is processed, metabolized, or where it accumulates once it passes through the skin into the tissues and surrounding bloodstream.  The DMSO you can taste seconds after putting it on your contaminated big toe or penis is obviously not in the tunica.

If you use this, do not forget to say "Hokus-Pokus" or "Abra Cadabra" at the exact moment that you apply it.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Jonbinspain on October 09, 2012, 02:57:03 AM
I have read about a few different solution using DMSO. One was DMSO,Castor Oil, Vit E.  Another was, DMSO, vinegar, castor oil. Any experiences or suggestions on this?
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: james1947 on October 09, 2012, 09:11:28 AM
Jonbinspain

I am proposing you two things:
1. Read Reply #288 by Hawk
2. Read all the posts in this topic (I have done it) and you will understand Reply #288 by Hawk
I don't remember no one that get help from DMSO except making the pocket lighter 8)

James
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Jonbinspain on October 09, 2012, 10:43:23 AM
Thanks James. I have read alternative opinions. Apparently, the active ingredient in this formula is the castor oil. DMSO merely facilitates it's absorption. I think the total cost is relatively low, and I'm willing to try anything. It makes sense to me that anything that is applied directly to the affected area will, if it works, be far more efficient than any oral remedies. These may well help, and I already taken many of them. However, you must ask yourself, how much of what you are taking will be used elsewhere in the body instead of helping the Peyronie's.

Incidentally, I have been trying Jelqing for a couple of months and found, that for me, it has increased blood flow to the penis. I have also found, in my case, that some Testosterone boosting supplements have increased libido. The curvature remains, however.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: muffslayer on October 11, 2013, 08:18:35 AM
I've been using DMSO with PABA and MSM from this site:

LINK REMOVED BY MODERATOR

I've used it 12 times now (12 days). And before that I used my own DMSO + SSKI 5 times or so.

My current penis is like this. My girth all down the right side has shrunken. And the same on the top/middle part of the left side, but not at bad at the bottom on the left side. I've gone down from 5" to 4.5" girth at the top/middle. And the bottom 5" to 4.75" girth, mainly because the bottom left side is better intact. However at the bottom it use to be 5", so I am still losing girth.

Most of my girth on the right side and left got lost when my peyronies these last 6 months, has been really aggravated by a myriad of things. Especially by smoking, which I have now quit, but sadly too late. But things like eating pork would also aggravate it. Pentox helped a lot, but I hated the brain fog and bad sleep it caused, so I dropped it.

Also my dick bends to the right, but not so much on full erection.

Anyway after doing this DMSO, amazingly the other day it seemed like my girth had increased somewhere along the penis. Even though the girth measurements basically stayed the same, and didn't show improvement. It seems like the left chamber of my penis had increased girth visually while the right remained the same. How do I know this? Well when I had 5" girth, at my full erection my foreskin would always pull back. Since I had gone down to 4.5" girth at the middle/top, and 4.75" girth bottom, my foreskin never pulls back on full erection. Well this day the foreskin kept pulling back on full erection, must have been the first time in a year or 2. But then again my measurements were still 4.5" top/middle, and 4.75" at the bottom. But my left chamber did look a lot bigger. Or somehow DMSO is making my skin tighter. But anyway this happened once a couple of days ago.

However today, my girth looks terrible flaccid, and I'm really scared. I'm dropping the DMSO, and going back to pentox. I had a semi erection, and my girth is bending more to the right, and is now going around the 4" mark!

I've took 10mg of cialis, and 800mg of pentox just now, and hopefully I'll be able to get a full erection I can measure. I don't really understand why 1 days my penis actually seems bigger one day, and the next, it's much worse than before. This has happened a lot though when it comes to my dick.

One thing I will say, using DMSO/PABA/MSM (DPM), or DMSO/SSKI (DS), is at first it seems like your penis gets better. For example when I started with DS my erections were hard and more frequent, caused more veins, and was like a topical natural viagra. But eventually my penis soft tissue felt sore and damaged. And with DPM my penis felt soft inside and soft on the skin, but eventually the soft tissue felt sore and damaged.

I think my penis is just going through an inflammation phase maybe. But I think if DMSO is used, it might have to be used once in a while. Like 1 day on, 3 days off. Because continuous use in my case seems to damage it.

Whatever the case, I'm off the DMSO for now. Even with the 10mg cialis, I don't feel I might be able to get a full hard erection. BTW that increase in girth I reported earlier was a natural erection, no cialis.

Anyway I'm kind of panicking, because I feel DMSO might be shrinking my girth. I have no idea. But I'm going to get off it for a couple of weeks, and go back to pentox.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Norm on October 11, 2013, 08:35:53 AM
DMSO is paint thinner. It was never intended to go on your body for any medical purpose. I would stay away from it. The only reason it is part of the formula is because it absorbs into your system and transports the other parts of the formula that do not absorb. I think the consensus of this group is that it is snake oil. Stick to the more conventional treatments. On a personal note, it made me stink to high heaven! People ran away from me!
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: inkhorn on October 11, 2013, 11:57:03 AM
I have used DMSO,following the Park's protocol averaging about 3 times a week for 6 months. Never had a rash or  any garlic taste. Regards Inkhorn
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: james1947 on October 11, 2013, 04:47:30 PM
inkhorn

The DMSO and Park's protocol helped regarding your Peyronies?

James
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: inkhorn on October 11, 2013, 07:21:35 PM
James- It's hard to say, when I started treatment, I started everything at almost the same time. Traction, Park's topical protocol, Al-car,L-Arginine,nattkonise, serratose.(not at home so not sure the last two are spelled right). Alittle later I added CoQ10 and daliy VED, following Old Man's protocol. Prior to that I only used VED a couple times a week for sex.Lastly over the last few months I am doing a regiment of HGH, to help produce new cell growth. There has been so many things in the treatment, unfortunately I can't know which things worked. All I know, is I've had no side effects from the DMSO. When I started treament, I had a dorsal curve of at least 45% and a curve to the right at about 30%. The curve to the right is gone. The dorsal if not better(which I think it is) is at least arrested.Uro feels less plaque, and I'm now able to have sex in the missionary position over the last month or so. Regards Inkhorn
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: LWillisjr on October 11, 2013, 08:40:14 PM
inkhorn,
Great to hear you are seeing progress!! While we all wonder "what was that one thing that helped", the reality is that it is usually a combination of things. So I doubt any one single thing was the cure. Always good to hear when one of us is winning the battle over this crazy disease.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: james1947 on October 12, 2013, 10:35:16 PM
inkhorn

Thanks for the information and wish you to continue to improve.
Yes, with so many treatment components it is impossible to know what helps and what not, but as LWillisjr has said what is really important is the improvement :)

James
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: IhatePD on October 13, 2013, 08:19:20 AM
I trained at jiujitsu in Philadelphia for several years and I can tell you that a lot of the practitioners used DMSO (Di-methyl Sulf-Oxide - probably spelt wrong) all the time for joint aches, especially in the knees. They would soak a small towel in it and wrap it around their aching joints and the pain would go away. I have used it myself and I can tell you that it relieved pain in a matter of minutes and reduced my swelling. It was like magic.

I can also tell you that IT IS NOT APPROVED BY THE FDA FOR ANY HUMAN USE IN THE UNITED STATES SO PROCEED AT YOUR OWN RISK,

When I asked my orthopedic about it before my shoulder surgery, he knew all about it and unofficially, had no problem with me trying it. He told me a lot of his athlete patients, especially wrestlers use it all the time.

It is used as a carrier for other substances for transdermal application. It penetrates the skin very easily and carries with it most other substances applied with it, i.e.: Vitamin E as Mr. Herzay suggests in his site.

You can real a lot about DMSO on the internet but again, it is not FDA approved so proceed at your own risk.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: muffslayer on December 01, 2013, 06:17:37 PM
OK guys, just to update you.

I haven't used DMSO for a long while, however my peyronie's pain and girth shrinkage I got from it continues to worsen.

Though I won't say a treatment with DMSO and a PABA/MSM or Iodine mixture is worthless, as other people seem to be having success. I will say however, that for some people, such as myself, it can considerably worsen the condition.

Realise I'm taking ALCAR, Omega 3, grape seed extra, coq10, ginger, and all sorts of other supplements too to help combat this condition. But ever since using DMSO, inflammatory is now common, and it's almost as if my corpus is left in a condition as it was exposed to a mild acid over time.

I'm not trying to scare monger. I just want to give a stern warning, that DMSO might leave you in a worse condition than before.

One example is hard flaccid. I use to get hard flaccid before this DMSO experiment.  But I cured my hard flaccid by messaging any pressure points/knots in the muscles around the penis area. I would no longer suffer with hard flaccid, my penis would be soft, but it was still scarred so I still had girth loss. Anyway after DMSO application, it feels like my penis has slight hard flaccid, but it's not hard flaccid, it's more of a raw feeling. Like I said earlier, it feels as if my penis has been exposed to mild acid over time.

At my current point, I'm at my worse point with peyronie's, and I blame it highly on DMSO.

Another thing, is I can't take low doses of cialis as this exacebates the pain, rawness, and loss of girth. Also I can't even take citrulline, as this too does the same thing.

My girth has gone around 4.25 at the top. And I use to be 5 inch all the way down before peyronie's.

Lastly. Everytime I feel this pain/rawness, my peyronie's does worsen, both look work, and less girth measurement wise. I've actually lost 0.5cm in length! Which never use to be effected. I took some pento earlier, which hasn't really helped at all with the pain/rawness. But I think I'll need to start taking it regularly, though I hate the brain fog and insomnia side effects. Also I'm going to try using hydro cortisone cream to stop the pain/inflammation. The pain doesn't bother me much, but knowing everytime I have this pain/inflammation, my condition does worsen a little bit more (as proved by my measuring). I notice by look too, because before it was just the whole of my right chamber losing girth. Then it started on the top left. Why I have 4.25 girth at top (lost girth on both sides), and still 4.75 girth around the bottom (lost girth on right side only). However I can feel my whole left chamber is becoming more inflammatory, including the middle and bottom.

I think one last thing I will add into the mix is gotu kola. I think my 3 tablets a day was really preventing it from worsening, even though at the time I thought it wasn't doing anything.

Anyway this is my stern warning. I honestly will not recommend dmso combination for your peyronie's. Like I said, I'm not saying it doesn't work for some people. But in my case, it made things much worse.

Also if DMSO is good for sore muscles, then it must be powerful stuff. But remember your penis is spongy tissue, don't forget that, try to treat it with mild, nice creams. Not strong chemicals. That's my advice.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: james1947 on December 02, 2013, 07:59:52 AM
muffslayer

As someone that read all the posts on this forum (I really mean all, from the start day of the forum) your post is not surprising me at all.
Very few successes are reported on the forum using DMSO.

James
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: 4Christ on March 12, 2014, 12:42:13 AM
Muffslayer,

Would you mind sharing what brand of DMSO you were using? Where did you get it from? Was it packaged in glass or plastic? Was it a USP Pharmaceutical grade of DMSO? The "grade" will be stated on the packaging. I'm sorry to hear about your experience, but am seriously debating incorporating DMSO into my treatment and would hate to make a decision not to if it wasn't the DMSO that gave you your problems, but the impurities within. Below are examples of different grades of DMSO from a leading manufacture: 

Available Grades:

Procipient® (dimethyl sulfoxide USP, Ph. Eur.): Highly pure grade of DMSO for drug delivery and healthcare applications.

DMSO Anhydrous: An extremely dry grade of DMSO for water sensitive reactions.

DMSO ACS Spectrophotometric: Contains low levels of UV absorbing impurities, for analytical applications.

DMSO ACS Reagent: Grade appropriate for industrial solvent cleaning use.

DMSO PharmaSolvent: The high purity of this product make it solvent of choice for the synthesis of Active Pharmaceutical Ingredients, and intermediates

DMSO EL 10 / DMSO EL 50: DMSO grades with extremely low metals content. Required in electronic applications such photoresist stripping. Enviro-S® ,

DMSO Enviro-S® : Enviro-S® (DMSO) An environmentally friendly alternative for sulfiding applications.

DMSO Industrial: A general purpose grade.

Thanks in advance,

4Christ
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Norm on March 12, 2014, 01:15:19 AM
4,
I won't try and discourage you from trying this, as you are new to Peyronies Disease and feel the need to try everything. I understand. Just keep in mind that DMSO was originally formulated as paint thinner! Later, vets found that it had some usefulness in the treatment of horses. Other than being a means to take some other medicine into your system, it has no therapeutic value, unless you need to thin your house paint or get linaments into your horse's leg. For every testimony you find here that DMSO helped, you will find tenfold that say it hurt or did no good at all. You are better served to spend your time and money on the standard, conservative treatments offered here. Lastly, it very often makes you stink so badly that no one can stand to be around you. With that said, go ahead. I know you have to try. I did.
Norm
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: 4Christ on March 12, 2014, 03:37:49 AM
Norm,

Thank you for the advice. I do realize what DMSO is and it's uses (there are many) and I've been familiar with DMSO even before discovering this Peyronies issue. It clearly makes logical sense IMHO to use this as a way to deliver a treatment of (blank) through the skin. Can I ask you what you tried to deliver through the skin with DMSO? Also maybe most important when dealing with penile tissue and not muscle, what brand and grade of DMSO did you try? (Was it packaged in glass or plastic? And were you treating hardened scar tissue or plaque? When you tried DMSO were you in the "acute" or "chronic" stage of this disease? Detailed answers to any or all of these questions would be greatly appreciated.

Thanks in advance,

4Christ
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Norm on March 12, 2014, 10:11:57 AM
Let's see. I was in the active phase. I was using the DMSO to transport Vit E oil. I bought it at a health food store. I remember there was something about it being 99 point something pure. I think it was a plastic bottle. I never got the chance to find out if it did any good because I smelled too bad. People, including my wife, steered a wide path around me. I think someone commented that I smelled like car exhaust. After noticing here the lack of successes with it, I stopped.
   Honestly, I think your time would be better spent on the mainstream therapies. This forum has about 7000 members. They have tried everything. If DMSO had done any good, there would be some testimonies here about it. But as I said, I know you gotta try. Just be careful. You only have one penis.
Norm
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: 4Christ on March 12, 2014, 11:06:45 AM
Norm,

Just in the small time I've been on this forum I've seen a number of people testifying to the positive effects of incorporating DMSO into their treatment. Just read this thread for starters.

4Christ
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: 4Christ on March 12, 2014, 11:28:57 AM
Judging only from the small time I've spent here, it doesn't seem like the mainstream therapies have been all that successful. Just my opinion, but I definitely don't feel it's a waste of time looking elsewhere. I believe as many angels as possible is going to be the key. Starting with diet. That's just my opinion from the little I've took in. Also when hitting something from many angles it may be hard to say what helped or didn't. I'd like to avoid the pharmaceuticals if at all possible.

4Christ
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Skjaldborg on March 12, 2014, 01:44:49 PM
it doesn't seem like the mainstream therapies have been all that successful.

Pentox worked very well for me and it is considered one of the mainstream therapies. I think a reasonable strategy would be to try the mainstream therapies first, and then move on to the lesser used treatments like DMSO.

-Skjald
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: james1947 on March 12, 2014, 04:59:37 PM
As someone who read all the posts on the forum, I was changing the world "used" to "successful" in Skjald post:
Quote
....move on to the lesser used treatments like DMSO

James
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Skjaldborg on March 12, 2014, 06:21:31 PM
I was trying to be diplomatic :)

-Skjald
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: 4Christ on March 12, 2014, 09:09:07 PM
Funny my thinking is completely opposite. Prescription med's will be my last resort. There are to many reasons to go into that here, but I have no intrest in the pharmaicia unless it's a last resort. Not saying I wouldn't, but again it will be a last resort. To each there own I guess. I just don't get the closed mindedness. Like I said from reading through out this forum so far it doesn't sound as if the mainstream "drugs" are doing all that good. As for therapies I've already started traction and hopefully Old Man "VED expert" is going to get me set for the Vacuum. But, as for the scrips or the shot's well I'm definitely not there yet and pray that day never comes. I guess we will see.

4Christ
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: 4Christ on March 14, 2014, 09:31:35 PM
Here is an interesting testimony I found on the use of DMSO and Iodine. I'm leaving this post in it's original state and posting it here because I feel this post is worth reading regarding this topic.
(If anyone is interested in reading the whole thread PM me and I'll send you a link).

4Christ

See post below:

 I found a great protocol to reverse internal scarring left from accumulated injuries: DMSO and iodine.

Over the last 15 years I’ve sustained a number of injuries from various ‘experiments’: pumping, stretching, hanging and other ‘adventures’, and as each injury healed everything seemed to come back pretty much as it was before. But the damage has been cumulative, and for the last few years, my EQ has been mediocre and declining with very poor engorgement of the head. I knew there was underlying scar tissue that was inhibiting blood flow so I tried the DMSO + ACV + castor oil mixture (Thacker’s) recommended for dissolving scar tissue associated with Peyronies. Didn’t see much improvement from that although I didn’t stick with it for the months and months it’s supposed to take. Having a vinegar-soaked dick got old real fast.

But last week I read about DMSO + iodine. I had already started taking nascent iodine for general health and I’d been using DMSO for other applications for over and year and was comfortable with it’s non-toxicity and general safety. So I thought I would try the combo topically. Using about 2 parts 99.9% DMSO and 1 part nascent iodine, I applied about 4 drops to the head and spread it all over with the side of the glass dropper. I also spread another 6-8 drops around the base of the shaft and about another 8-10 drops on the perineal and anal area as I knew my prostate was not in great shape. Right after applying the solution my penis shrivels a bit but I just let it soak in and dry. One application first thing in the morning and one more about 12 hours later. The whole solution is 8 drops nascent iodine, 4 drops MgCl2 and 12-15 drops 99.9% DMSO. (Always clean the skin well before using DMSO.)

Within 2 days I started noticing increased engorgement of the shaft and head! Waking up at night and morning with good hard wood, unusually hard by my standards. On the 3rd day I felt a slight pulling inside my shaft during an erection, like scar tissue letting go. That disappeared in a few hours and my EQ increased again. In another 2 days I felt a similar pulling inside the spongy glans tissue. I gently massaged that and it melted away in couple of hours. There is such a dramatic increase in glans engorgement now - I’ve gone from a less-than-half-full semi-mushy glans to a full, shiny and sensitive plum. In fact, I’m getting a little carried away with the revived sensation I’m getting, it’s like I’ve turned back the clock 15 years or more! ;) I’m late 40’s.

After the DMSO+ACV flop (it might have worked if I’d stuck it out longer), I certainly didn’t expect the rapid results I am getting with DMSO + iodine. The protocol I read for scar reduction talked about the SSKI form of iodine (Lugol’s), but nascent iodine is supposed to be much more powerful and at much lower doses too. Nascent is what I had on hand so that’s what I am using and enthusiastically recommending, but Lugol’s iodine would probably work well too.

I’ve had issues with venous leakage for even longer than the mushy glans which is why I’m applying it at the base as well. (Although DMSO penetrates into the bloodstream so well that I probably don’t need to spot-treat that close together.) I read that DMSO + iodine can dramatically heal hemorrhoids in just 3-4 days, not just reducing them but healing the weak and damaged blood vessels fast. I’ve never had hemorrhoids but it sure is making a big difference in my EQ from base to tip.

And my prostate has bounced back big time! For several years my urine flow has slowly been weakening, recently to a mere trickle that took forever to empty my bladder. That started changing after day 1. It’s been close to a week now and I’m able to pi$$ a good stream that doesn’t feel restricted like before. Not with quite the force it had 20 years ago yet but definitely progressing daily in that direction. Needless to say, the improvement in my prostate coupled with the glans engorgement has given me an OQ that I’d never thought I’d experience again! Precum volume has increased a lot as well as ejaculation volume.

The only ‘side-effect’ I’ve noticed is sometimes my prostate feels a little tingly during the day like it’s looking for an opportunity to expel an excess of seminal fluid. Maybe this is what an unmilked cow feels like. Could be scar tissue is dissolving there too, I don’t know, but the remedy is delightful ;) Haven’t noticed any increase in sperm production, but the tadpoles are definitely swimming in a much bigger lake.

I’ve also been doing some dietary changes too: more raw food, minimal sugar. Those changes are very helpful but they are not new for me. It’s the DMSO + iodine that is making a dramatic and rapid difference!
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Iceman on March 15, 2014, 05:01:03 AM
does any one really believe this guy????????

What is MgCl2???

Has any other person tried this - seems like total crap to me. - so why would someone spend the time and effort to write this??

Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: james1947 on March 15, 2014, 05:04:40 AM
4Christ

It seems that DMSO and Iodine is the miracle silver bullet for Peyronies that all of us will like to find.
Cure of Peyronies in three days is amazing 8)
No need for VED, Pentox, Xiaflex and surgeries :)
I suppose in three days you will be free from Peyronies. Happy for you :)
If you will sale kits for 3 days Peyronies cure, you will become millionaire shortly 8)

James
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Iceman on March 15, 2014, 05:12:00 AM
whats he trying to sell/achieve??...

found it - hes trying to flog this product ...Lugol’s iodine

he keeps on mentioning its name

what a wanker
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: 4Christ on March 15, 2014, 10:08:16 PM
Iceman,

I'm not trying to sell anything. Lugol's Iodine is not a certain "product" or a "brand" to sell. It is a specific blend of Iodide and Iodine named after the doctor who invented it. Many companies sell / offer a "Lugol's" blend of Iodine usally at 2 or 5% but you can find higher. I haven't even mentioned the brand name of what I'm using, so I'm obviously not on here selling anything. I don't mean to be rude, but your comment seriously shows your ignorance. I'm only on here doing my best to be helpful while looking for a way to attack this thing head on. That's it, nothing more.

4Christ
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: 4Christ on March 15, 2014, 10:22:47 PM
[quote It seems that DMSO and Iodine is the miracle silver bullet for Peyronies that all of us will like to find.quote]

James1947,

I have no idea that's for sure!  Although I found that post to be very interesting on the topic, therefore I posted it here for people to see. Sure would be nice if it could help. Just like Iceman asked, why would someone take the time to write that?? Also that is just one post from a HUGE thread on the subject. I know one thing I'm willing and able to try it so I'll let you know how it goes! Although I have definitely not said there is no need for any other treatment. I'm scared as can be right now and plan on putting my best battle plan together to fight this thing! I'd be happy and thankful enough to fix myself! You can have the millions!

4Christ
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Iceman on March 16, 2014, 12:44:44 AM
sorry 4 christ

can you please tell me the exact ingredients/formula you use and i will give it a go:)

i do notice you use this: 4 drops MgCl2.... is this important??

thanks...
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: dplookin on March 16, 2014, 06:09:34 AM
I think most of us are ready to try just about anything to solve this problem.  I know I am whether it sounds weird or not.  But, those who try the Iodine and DMSO should be careful.  Too much Iodine can cause some major problems.  I suggest looking up the side effects of getting too much Iodine.  Just FYI.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: 4Christ on March 17, 2014, 08:51:04 AM
Iceman,

Apology excepted and no hard feelings.
I have experimented very little so far with these topical treatments. Currently I am using what time I have between working to research this stuff and research some more (which is how I found that post below).  I have ordered many products, but have not put my game plan completely together on what exactly or how exactly I'm going to implement these things, but I will be very shortly or as soon as life allows it. The large post below concerning the DMSO and Iodine was taken from another forum (non Peyronies related). Again I posted it here because I feel that it may be good information ( I don't know ) but I hope it is. As for the MgCI2 mentioned below, I believe he is talking about Magnesium Oil. Something I currently do have on order and feel I'm most likely deficient in.

4Christ
 
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: 4Christ on March 17, 2014, 09:16:57 AM
Dplookin,

 I agree, and plan on staying well within the recommended daily dose of Iodine. Instead of getting it orally as recommended on the bottle, I'll just be getting it topically using the DMSO as a carrier to take it through the skin and directly into the area of concern to hopefully break up the plaque / scar tissue. I recommend Googeling DMSO SSKI Peyronies and reading as much as you can find about it if you are interested in trying. The thread where that post came from is 40 pages long. If you would like I could PM the link to you. There is other info on the subject to be found too. Both DMSO and Iodine are things I was familiar with and have used for various things before discovering this peyronies condition. That's why I'm now looking into this for possible treatment or at least help with my treatment. Meaning using in conjunction with diet, supplements, traction & VED. Again I'm still in the process of researching and developing my battle plan to fight this.

4Christ
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: dplookin on March 17, 2014, 12:35:44 PM
4Christ..........Thanks..I will try to find this info on the Internet.  dplookin
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: dplookin on March 18, 2014, 07:01:09 PM
If you overdose on Iodine/Iodide, a little over 2 grams of Vitamin C will take care of that, or Chocolate will Help.  So, if taking Iodine, only take Vitamin C 2 hours before Iodine or 2 hours afterwards. 

Chocolate has Bromine in it which kills the power of the Iodine.

Just FYI
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: 4Christ on March 18, 2014, 07:50:00 PM
If you overdose on Iodine/Iodide, a little over 2 grams of Vitamin C will take care of that, or Chocolate will Help.  So, if taking Iodine, only take Vitamin C 2 hours before Iodine or 2 hours afterwards. 

Chocolate has Bromine in it which kills the power of the Iodine.

Just FYI

Thanks, that's good to know.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on April 09, 2014, 05:30:54 AM
Hi,

Im pretty confident that a mixture of:

70%DMSO
Some ACV
some Magnesium oil
some nascent iodine
some vitamin E
some l carnitine.
and some castor oil.

all soaked in  a cloth and applied with a safe plastic wrap(Heal Yourself At Home (http://healyourselfathome.com/HOW/THERAPIES/DMSO-MSM/DMSO_compatibility_chart.aspx)) is helping me in a good way the last 2 weeks.
I apply it as often as possible and observe the first time changes in my calcified plagues.(more about it here: Introducing myself and treatments - Peyronies Society Forums (http://www.peyroniesforum.net/index.php/topic,4863.0.html))
I started to have kind of morning wood and my penis hangs fuller while palpation fo the plagues makes them seem softer.

------------------------------------------

I found another anectodal report about vitamin C combined with DMSO here: http://www.csom.ca/wp-content/uploads/2013/01/Melting-Calcium-Deposits-with-Transdermal-Dimethyl-SulfoxideAscorbic-Acid-Mixture-25.4.pdf

The guy is saying that it "melts" away calcium deposits. Anyone tried Vitamin C + DMSO?
I will try that too but as I understand I have to use it with some time distance to iodine as it might contradict each other as vitamin C "melts" minerals I understand.
__________________
I also researched about how DMSO is actually giving ability to let substances go transdermal. It seems that dmso isnt moving it with other susbtances but rather opening the membranes for some time to allow other substances to freely enter.

Very interesting was this scientific paper:
Serratiopeptidase Niosomal Gel with Potential in Topical Delivery (http://www.hindawi.com/journals/jphar/2014/382959/)

They used a serrapeptase gel with DMSO. Figure 4 is very interesting as it shows that even after 4 hours, there was still an uptake of the serrapeptase.
Now Im not sure how the serrapeptase in this study applies to the serrapeptase that is available to us.
They speak of SRP niosomes which might have a much smaller molecular weight then that what we can buy. Serrapeptase as it is available is said to be not able to penetrate transdermal with DMSO due to its high molecular weight.
Serrapeptase is very thoroughly researched and in theory probably one of the strongest substances that is able to "melt" away calcium deposits.

But as with other oral treatments Im not very confident about the impact, if taken oraly, cause much is destroyed in the digestion process and even then Im not sure how much reaches the Penis or even the plagues(which might sit in the tunica which isnt very much swimming in blood so to speak).

Hope someone can follow these thaughts and chime in.
I have to say I feel very alone in this endeavour. But Im willing to take risks as life without a functioning penis is no fun at all.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: 4Christ on April 09, 2014, 01:57:32 PM
Thanks for the DMSO safe plastic chart. So what exact type of plastic are you using?
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on April 09, 2014, 03:22:36 PM

The thin wrap you get in every supermarket to wrap food.(Plastic wrap - Wikipedia, the free encyclopedia (http://en.wikipedia.org/wiki/Plastic_wrap))
Its made of Low-density polyethylene.

They had a test of the wraps in a eco test magazin and mine was declared as clear. Only one of the 10 tested was mixed with PVC(which is absorbed with dmso) but also declared on the outside.
I understand that most these days are build from    polyethylene. But they were manufactured from PVC centurys ago.
If you are unclear about it and using it everyday I would check back with the manufacturer.

I also use a thin sheet of fabric soaked with the solution wrapped around my penis and the plastic wrap over it to.
This way you can also open the plastic wrap( which I use in a double layer) and apply some more dmso or solution/supplement to the fabric after some time. I do this to extend the permeability of the dermal layers. Refreshing the power of the solution also so to speak.

The plastic wrap I use is bigger in size then the soaked fabric to avoid getting anything from the outside mixed onto the solution and also to have anything clean so I can walk around etc.

When at home I strap often into the extender while having the wrap on. To immeadiatly attack any available stretchability of the plagues.

I noticed that only short applications of the solution for 20 minutes a day do soften the plague but they return to its hard state within hours. when used the whole day or multiple times they are even the next morning rather soft. I plan to use it even during sleep at some point.

Im ready to do this for at least half a year without a pause.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: 4Christ on April 09, 2014, 07:17:32 PM
What brand are you using? http://jonbarron.org/article/rap-food-wraps#.U0XUp4l5nTo
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: 4Christ on April 09, 2014, 08:33:12 PM
Melting,

You are not alone! I'm very busy, but will chime in ASAP. I'm with you on the DMSO and I'm also considering light and heat therapy.

4Christ
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Nemo on April 09, 2014, 09:35:58 PM
Guys, I suppose I am quickly developing a reputation around here as a stick in the mud, but it's because I've been active on this forum for years and have gone through many of the "therapies" you guys are talking about. I've tried Topical Verapamil, Iontophoresis, Thacker's Formula (DMSO), VED, Heat ... and all manner of supplements.  Before you go to great time, effort and expense wrapping your penis in plastic with DMSO-based solutions, read the entirety of the forum members' experience (myself included) with DMSO. 

Nearly everyone really got excited at first, as our penises seemed "softer," and the plaques seemed less hard - some even thought theirs were breaking apart. Many of us noticed stronger erections while using DMSO (I did).  However, not one single person saw any reduction in curvature with DMSO and all of us - after MANY months using it religiously - eventually gave up. 

I'm not saying this to bring you down, but to save you repeating history. Read the history here - that's what this forum is here for.  When I see you getting excited about DMSO and also talking about light and heat therapy, my heart sinks because we've been there. That stuff just doesn't work. And in the case of both heat and DMSO there's the potential for actually harming yourself if you're not extremely careful. 

So be careful, guys. Read all you can, and treat yourselves conservatively with the best we currently have to offer which, basically amounts to: Pentox, Cialis, VED and traction; or second line treatments like the supps COQ10, L-Arginine, etc. The only true physical change I ever noted with anything over the last 12 years was length gained back with the VED. That's it, but I was thrilled to get that.

I just hate to see a "second generation" of guys going through the same tired experiments some of us have already worn out. 

Best to you,
Nemo
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: james1947 on April 09, 2014, 11:07:18 PM
Thank you for the post Nemo.
You are able to make such a post because you are around from 2006. :)
Many "New experiments" were done already in the past. The problem is that many new members, before starting such a "New treatment" are not reading the forum.
So they spend money, time and effort on things that were tested already and the results were very poor at best or not results at all.

James
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: 4Christ on April 09, 2014, 11:53:53 PM
Nemo,

When trying any of these alternative therapies, did you enforce a strict diet? With all due respect, not everything works for everybody. Just because something didn't give you results doesn't mean someone else can't get them. Everybody is different and this condition varies greatly from person to person. You are speaking as if "one size fits all per say" and with this condition it most certainly doesn't. Trust me I have been reading every chance I get and not just on this forum. I've seen plenty of  positive results / testimonies from the below mentioned therapies. Sorry nothing has worked for you, but that just doesn't mean nothing can for anyone else. From my studies so far I recommend starting with very strict diet change. Although I'm referring to someone in the beginning stages less then 6months. Many people can heal themselves naturally. These therapies can help with that process.

4Christ
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: james1947 on April 10, 2014, 12:04:02 AM
4Christ

It is not just Nemo that DMSO treatments didn't helped.
Read carefully all this topic, from the start and you will understand.
From the other side, you and all the others that want to try it, just do it. :) It is your right and no one here is holding you back. :)

James
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on April 10, 2014, 06:19:23 AM
What brand are you using? http://jonbarron.org/article/rap-food-wraps#.U0XUp4l5nTo

As said Im located in germany and I use a local brand, it is named Ja!Frischhaltefolie.
They had a test in germany if any of these were contamined and mine and most others were not. (http://www.oekotest.de/cgi/index.cgi?artnr=100957&bernr=01&seite=01)

So you might check any of the available brands for tests or test them yourself or ask the company.
You dont need the plastic per se. Wrapping with some more layers of cottonfabric(totally white, I suppose anyone following know show to use DMSO..) might work too, but albeit would leak some of the solution outside(needing you to use more) making it messy.
I dont have much of the plastic coming into contact with dmso soaked skin anyway. Its just the top layer.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on April 10, 2014, 08:08:53 AM
I just hate to see a "second generation" of guys going through the same tired experiments some of us have already worn out. 

Best to you,
Nemo

I think I read almost everything available. And Im thankfull for you post and the trials you guys did go through back then. Its very helpfull input.

---
VED and traction alone or combined did nothing to my calcified plagues. And they wont be able to do that on their own.(try to vacuum or stretch a stone)
---
From the conservative medicine in germany Im told only surgery will help. Any other treatment isnt supported cause its to expensive and didnt show much improvement in studies. I did know more theory about peyronies then any of these guys. I was a pain in their a$$ as they have no clue at all about alternative treatments nor studys related to this or similar conditions. Their attitude to not check for alternative and new scientific approaches on a daily/weekly base show me that they are basicly overpaid quaks keen to earn money with surgery.
My heart weeps thinking of any of clueless patients getting butchered by them(I was one when I basicly was forced/no alternatice to get cut my foreskin cause of another condition years ago. Im still in tears when thinking about my foreskin taken away from me)

---
Pentox, cialis, L-Arginine basicly increase the blood flow. They wont dissolve any plague if the body isnt willing to do so. Pentox and cialis have their own risks and side effects.

They are usefull cause they will at least enable oral supplements to get theoreticly somewhat near the plagues. Blood flow is very important with this condition.
---

For as many people as DMSO didnt help you will find as many people where "conservative" treatments didnt help I think.
DMSO on its own is already proven to have a profound effect for many conditions. Its a very safe substance used in the right way.

But it isnt a miracle solution for peyronies condition on its own.

The most important thing that DMSO is enabling us is to be able to move substances into the plagues that are known to dissolve fibrous plagues, calcium deposits and scars.
These substances taken orally most times never reach the plagues, let alone penetrate them, and if, then only in minuscle amounts.

Thackers formula on its own might help some people but I dont see how these ingredients alone will solve this for me.
When I read the old posts I see why people failed. They didnt use it often enough and many just used the thackers formula. The ingredients might not be enough to dissolve the softened plagues for good.
Also DMSO needs to be applied for best use in a 80% solution/but not over 90% so it is penetrating all layers/cells to enable them to take up other supplements in. Thackers formula alone is too diluted IMO.

Then check for guys like nick:
http://www.peyroniesforum.net/index.php?action=profile;area=showposts;u=25
He seemed to throw anything that seemed to help into a solution with DMSO. He reported a great difference with his method and then dissapeared.
The reason might be that the tone in this discussion is for sensitive people rather discouraging to try anything that is not mainstream.(Im as stubborn as my plagues ;) )

Also its clear to me that you need to apply the DMSO/supplements basicly all day and night everyday everynight.
It was reproted by several people, and this is also my observation, that the plague will turn back to its hardened state rather fast.
When I applied the thackers for only one time per day it softened it but was the next day in the same hardened state as before.

Its similar with a traction device like an extender. If you use the extender at maximum traction for 2 hours a day you might lengthen your penis for temporal time(the collagen fibers) but it will return to its old state. Even if you use it for a year everyday for 2 hours it wont achieve much.
But when you wear it all day everyday 16/7 you will elongate your penile tissue permantly.
Same with tendons(think of professional gymnasts, they do it all day everyday to achieve that flexibility).

The tunica itself is a very hard tissue that is very hard to alter. But it is possible and proven.
The reason is that it is arranged in a 2-3 layer mesh perpendicular to each layer.
A scar is many layers interconnected in a chaotic mesh to avoid that the human/tissue will be torn apart again. It has to be penetrated, weakend and dissolved in its core. And I dont see how that will be possible by any oral treatment alone. Espacially if the tissue is the penis.
Xiaflex did work for some cause the solution was injected right into the plague. But the very act of having a needle through your tissue might attract more scar tissue.

All that is available to me that has the possiblity to penetrate the callcified plagues is DMSO together with supplements that are able to dissolve scar tissue/calcium deposits.

So what I do is:
I apply the supplements together with DMSO all day and night.
I mix for each supplement a seperate batch to avoid downgrading any supplements to another one.
I take turn with the batches and use a new wrap each time.
I try to put a fresh solution on it for as often as possible. I aim for every 2 hours.
I use a traction device all day along with the solution to attack any instability in the plague as it happens.
I use appropriate heat for as often as necessary.
I use a waterpump at the end and the start of the day to attack the possibility to fill the plague with healthy blood.

I didnt see anyone doing something similar.
And I think such an "extreme" approach is neccesary to get rid of these plagues.
As if just done once or twice a day they will return to its state again.

For me it seems many of the people who used thackers formula or DMSO just put a small drop on a hot stone over and over again.
Im sorry if I step anyone on his foot or his beliefs.
I hope someone can follow my thoughts and think through them with an open mind.

I write out anything that I can think of so anyone who is interested can see where Im coming from. I will try to answer any question coming up.

The improvements gives me big hope. Im confident that if Im even more resilient and stronger then the plagues then I will overcome them.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Skjaldborg on April 10, 2014, 08:50:28 AM
For the record: VED stretches the healthy tissue around the plaque, not the scar tissue itself. The "vacuuming a stone" is not an accurate metaphor.

I do hope DMSO works for you and please post your improvements.

-Skjald
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: 4Christ on April 10, 2014, 09:14:21 AM
Thank you Melting, well said!
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Nemo on April 10, 2014, 09:53:48 AM
Well, all I can say is good luck.  Document yourself and any progress religiously (with pics) so you can add to our knowledge on this.  Again, good luck.

Best,
Nemo
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: dplookin on April 10, 2014, 11:22:21 AM
Nemo............I appreciate your comments below, all of them.  This problem with Peryronies is very depressing, and considering how many people are fighting with it, it is Really Depressing.  I have been trying Everything with absolutely no success at all.  I couldn't handle the Pentox due to the side effects I had.  I can't really afford the Cialis.  My budget and it's cost don't go together, and definitely can't get the other Prescription type medicines.  I do use a VED, but it's difficult to see how it is going to help.

But, I did enjoy reading your comments / posts below..........more is welcomed.

Thanks, dplookin
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on April 12, 2014, 01:39:43 AM
I dont plan to report on every single thing that happens but its rather profound for me that I did wake up in the middle of the nigth, for the first time since ages, to a nocturnal erection. I blame it solely on the DMSO protocol Im following.

The many plagues I have basicly prevented me from having a hard normal errection lasting errection. The blood and hormones want to but the plagues seem to prevent veins and smooth muscle on expanding soft tissue to maintain an errection for longer time. So this Is a big difference having to wake up to an errection.

I dont have big dents apart from some twisting and hourglass on the left side which also shortens that side. I also have no bend but I did loose the natural bend I had before Peyronies.

On the left shorter side I had a very thin sensitive cord that seemed to be like a hard(thrombosed?) small vein.  And it was kind of glued superficialy to a rather big plague on that side. Im pretty sure that this "vein" did free itself from the plague. Its now "freely" moving but feels very tender. Its like a guitar string.

I did have some skin irritation/peel due to using some 99%DMOS too much in one batch. Zinc based cream helped me rather fast. Other then that I feel no side effects from the more or lesss constant DMSO/supplement wrapping.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on May 26, 2014, 11:12:23 AM
After one month of more or less constant use I have great erections and soft plagues.
But I cant sense that the plagues got smaller.

I had 3 stops for like 3 days due to too much DMSO which gave me some skin problems. Whenever I stop it the plaguess seem to get harder again.

The vein that got loose from a plague is probably a lymphatic cord.

I think I have to continue this treatment and find a susbtance or combination that effectivly dissolves the plagues.

Apart from the minor skin problems I discovered no adverse effects of this treatment at all.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Freemason on August 29, 2015, 01:09:11 PM
DMSO is paint thinner. It was never intended to go on your body for any medical purpose. I would stay away from it. The only reason it is part of the formula is because it absorbs into your system and transports the other parts of the formula that do not absorb. I think the consensus of this group is that it is snake oil. Stick to the more conventional treatments. On a personal note, it made me stink to high heaven! People ran away from me!

Not to argue here...but DMSO isn't paint thinner. It has application in paint thinner and other seemingly toxic applications for its ability to penetrate and dissolve substances.  DMSO is FDA indicated for interstitial cystitis.  There are certainly side effects to DMSO that are pretty common in a lot of drugs. I'm not saying it's safe for use on our penis by any means.  But one thing is for sure...it will penetrate the skin...what that means idk. I know this is an older thread but I'm new and reading through a lot of posts to try to make an informed decision on treatments.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: james1947 on August 30, 2015, 04:04:20 AM
1. Yet in the United States, DMSO has Food and Drug Administration (FDA) approval only for use as a preservative of organs for transplant and for interstitial cystitis, a bladder disease.
2. In 1970, the FDA approved DMSO for the treatment of musculoskeletal disorders in dogs and horses
3.....in 1978, it was approved by the FDA in humans for the therapy of Interstitial Cystitis
4.Conservatively, hundreds of millions of patients have been safely treated with DMSO worldwide. DMSO is a substance of extraordinary low toxicity.
From WebMD:
http://www.webmd.com/vitamins-supplements/ingredientmono-874-dmso%20(dimethylsulfoxide).aspx?activeingredientid=874&activeingredientname=dmso%20(dimethylsulfoxide)
So as mature people, everyone can decide how to proceed.

James
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Youngdude22 on November 01, 2015, 03:17:42 PM
I'm ready to give ALK5/DSMO a try. There is research supporting ALK5 as effective inhibitor of TGF-B growth

Transforming growth factor (TGF)-β type I receptor kinase (ALK5) inhibitor alleviates profibrotic TGF-β1 responses in fibroblasts derived from Peyr... - PubMed - NCBI (http://www.ncbi.nlm.nih.gov/pubmed/20233292)
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: kuaka on November 02, 2015, 08:52:18 AM
DMSO is primarily a carrier.  If used, do NOT use latex gloves as it will carry latex into your system.  Bare handed is best.  It is in my stand by arsenal for cancer if I ever get it.  I would use it as a carrier for an oxidizing agent.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Nemo on November 03, 2015, 02:19:39 PM
Kuaka, given DMSO's failure as a treatment (carrier) in Peyronie's, I wouldn't be too hopeful that it's going to be much help in fighting cancer. ...

Nemo
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: kuaka on November 04, 2015, 10:57:25 AM
The DMSO is simply a carrier.  What it is carrying is the key to treatment of whatever you are trying to treat.  It is primarily to enhance topical absorption of "something"...  The oxidation agent would be the primary "treatment".  Just my thoughts on the matter.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Nemo on November 04, 2015, 02:05:32 PM
I understand DMSO is simply a carrier.  My point is that if using DMSO as a carrier to cure Peyronie's has proven ineffective, I'm a but surprised you seriously think you could combat cancer with a similar approach. That's all.

Nemo
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Jonbinspain on November 05, 2015, 10:45:17 AM
I have tried using DMSO 90% gel with various other ingredients that supposedly will combat the plaque. Organic apple cider vinegar, castor oil, Vit E oil ( both pure organic) even tried coconut oil too!  Sh1t!, There's next to nothing I haven't tried in fighting this damn disease!

Result? Nada, nothing, zero. Now whether that's down to the inability of DMSO to penetrate through to the plaque in the tunica, or the ineffectiveness of the ingredients in combating the plaque, I don't know. But, over several weeks/months it did absolutely nothing to affect the plaque in any way, as far as I could tell.,
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Jonbinspain on November 05, 2015, 10:46:03 AM
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Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: kuaka on November 06, 2015, 09:56:57 AM
Cancer is quite a bit different than Peyronie's.  In fact, Cancer has been cured at least 30 different ways, but the medical establishment can't make any money off of an actual cure.  Tumors in general don't like oxygen, as their growth is actually a cellular survival move of rapid reproduction when the cell's survival is threatened (by insufficient oxygen in this case).  This is one major reason tobacco use is carcinogenic.  Not only does it introduce damaging elements, it reduces the oxygen available for your own natural processes to eliminate the damaged cells AND triggers rapid cellular reproduction in those same cells.

A "new" cancer treatment is just now on the market which supposedly works "with" your immune system as opposed to the "kill everything but the patient" approach of radiation or chemo "therapy".  If it is exceptionally effective, I expect the results to be distorted and the price to remain outrageous.  If it is marginally effective, it will be pushed.  Such is the "business" of "medicine".  Yes, I'm a bit jaded...but I have reason to be.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Nemo on November 06, 2015, 02:22:48 PM
Kuaka, I'm not trying to start an argument with you, but I do like to try to hold forum members to account insofar as the soundness of the medical talk we engage in here - reason being, if this forum holds itself to a rigorous standard in terms of scientific inquiry and discussion, it has a whole lot more credibility and can be looked to for better advice by those seeking advice. It's in this vein that I bristle when you say things like "cancer has been cured at least 30 different ways, but the medical establishment can't make any money off an actual cure."

This is ludicrous on so many levels, it ranks up there with the internal combustion engine that runs on water, the fake moon landing, FDR sacrificing the Navy at Pearl Harbor, the CIA inventing AIDS, etc., etc. If you actually believe there is a cure for cancer and that generations of countless human beings working in the medical sciences (most of whom having themselves lost family members to cancer) have actively, successfully engaged in a massive conspiracy to hide this revelation from the world, then I can only say I don't share in this belief. And I hope you'll refrain from putting forth this kind of stuff on these forums, because ultimately, I think it damages the credibility of the entire forum when Peyronies Disease sufferers come here looking for sound medical advice and find stuff like that. 

We have to deal in facts here - conjecture is fine if it's labeled as such. But what you're talking about veers off into "conspiracy theory."  And just to maybe make my point a little more specifically, imagine a guy comes here looking for info on whether DMSO could be useful in treating Peyronies Disease (I used it myself years ago).  He finds this thread, sees people talking about the application of DMSO and sees one who touts its merits and also believes it can be used to cure cancer, and further that cancer cures abound, the medical establishment just won't release them. You see what I mean?  Your opinions on DMSO just got undermined by your conspiracy theories on cancer in my opinion. That's all I'm saying.

Take it for what it's worth.

Regards,
Nemo
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Jonbinspain on November 06, 2015, 04:11:53 PM
Sorry, Kuaka, but I'm with Nemo on this one.

Aside from any argument about its validity in treating cancer, this site is here to try and supply relevant information to Peyronies suffererers from those who've experienced trying all mooted remedies for the disease.

 If anybody has experienced benefit from using topical DMSO based applications on Peyronies plaque, I'd like to hear about it. Personally, I found it useless.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: kuaka on November 07, 2015, 05:15:29 PM
I didn't say it was much use in this case.  I don't hang any real hopes on it as such otherwise either.  It is only one component, and a small one at that.  I don't believe we will have a "single" treatment of particular value, with perhaps the exception of Magnesium.  I know "we" in general are Magnesium deficient.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: james1947 on November 14, 2015, 06:39:22 AM
Quote from Nemo:
Quote
...if this forum holds itself to a rigorous standard in terms of scientific inquiry and discussion...
Are you sure Nemo that this is still the case?
Just wandering

James
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Pey-penis on December 30, 2015, 02:58:02 PM
From my experience it has shown that DMSO can transfer iodine through the skin. In the case of Peyronies can only soften scar.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Freemason on January 02, 2016, 01:38:37 PM
Just my two cents. DMSO is a carrier into the skin and a pretty powerful one at that. It does have anti inflammatory properties...doesn't mean by itself it dissolves Peyronies Disease plaque..don't think that's the case but combines with other compounds it's certainly possible.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Jonbinspain on January 02, 2016, 05:58:02 PM
In my time on this site, many people, including myself, have tried various DMSO based treatments. I personally know of very very few, if any, reports of success.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: james1947 on January 03, 2016, 07:27:33 AM
I can witness as someone that read all the posts until August 2015 that I don't remember no one that DMSO helped.
But of course each one can do with his penis as he wish.

James
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Freemason on January 03, 2016, 11:40:53 AM
DMSO is a carrier and an effective carrier. That's about it. Some anti inflammatory properties. It's not a plaque or scar dissolving compound. It's a carrier. So if some are using it alone it won't do anything.  The key is mixing it in the right mixture with other compounds that may offer greater effectiveness against Peyronies Disease.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Freemason on January 03, 2016, 11:47:47 AM
I'm going to have a compounding pharmacy make up a mixture of DMSO, Emu Oil, and Super Oxide Dismutase and Vitamin E and see what I can do over a 3-4 month period.  Any compound that is used must be used for at least 3 months. We can't use it for 1-2 weeks or a month and say well this doesn't work. As we all know it's a marathon not a sprint unfortunately.  We don't use traction or VED for 2 weeks only do we?  This is why clinical trials on compounds or injections are done over a 2-3 month period. 

It would be intersting to have Polls on here and be able to see who has used what and how effective.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Jonbinspain on January 03, 2016, 12:32:50 PM
The question is not whether DMSO is transdermal, we know it is. But, so far there is no evidence that it is capable of penetrating as far as the tunica. If it can't get through to the problem, it matters little what it's carrying with it.

I tried DMSO 90% gel with organic castor oil, pure Vit E oil and a Organic apple cider vinegar. It did absolutely nothing over a period of several weeks.

I wish you success, but I wouldn't get your hopes up too high.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: james1947 on January 03, 2016, 08:14:29 PM
See Jonbinspain answer,it is mine also

James
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on January 25, 2016, 07:20:22 AM
I used now since posting first on this topic solutions of:

DMSO + Iodine
DMSO + Magnesium
DMSO + Ascorbic Acid

Applied topicly onto the skin and through the urethrea while slightly clamping of the base with a hand.(inserting an eye dropper or pippet into the opening)
This takes much trying and exercise until one gets it right. Keeping a very clean enviroment during dmso use is very important(see all my other posts on this topic)

I varied the % of DMSO and the other ingredients throughout and have no conclusive opinion what is the optimum.
IMO the best way to approach is to start with something like a 50% DMSO solution (basicly pure DMSO + same amount distilled water) and then add the ingredients. At higher DMSO % the possiblitiy of burning skin gets higher. Still 90% or more DMSO solutions are possible to apply.

What helps tremendously is to have something like a a aloe vera solution handy which soothes the skin. Washing a DMSO application away with water can increase the burn(water and dmso interact!)

Continious application daily or as often as possible is the most important IMO. I noticed improvement after some weeks but whenever I stopped the tissue/plague hardened again.
This is a very tedious thing and I would say it needs to be done everyday for at least some months to have lasting improvement.

The plagues/calcifications will soften and I suspect its possible that they partially dissolve or get circulated by blood again.

My result is that peyronies isnt affecting me anymore.
I started with profound hourglassing which is now totally gone. I still feel some plagues but I have no pain nor any problems with intercourse.
In my opinion supplementing such a protocol with heated air or waterpumping at low pressur(hg) is very beneficial. It helps blood circulation to and around the plagues stretching them(traction can help there too).

Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Pey-penis on January 26, 2016, 03:46:54 AM
Hello Melting!
One can try the other methods with a success deemed here in the forum as useless. When it comes to the use of iodine it is also used in iontophoresis to soften connective tissue - scars, keloids, adhesions and bumps. Vitamin C can be used to effect elasticising walls of blood vessels, anti-inflammatory, and enhances the effects of immune system and additionally the use of acetic acid helps to dissolve calcium deposits by converting insoluble carbonates to soluble acetates - spurs, bony growths, periarthritis, myositis ossification's. All this doctor does not tell You :-)
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: james1947 on January 26, 2016, 07:53:31 AM
What long time members are always emphasizing is if a treatment helps someone is not for sure will help others.
The combination of DMSO with Iodine, Magnesium, Ascorbic Acid is helping Melting and I am pleased to read that.
I hope other members will try this treatment and will report successful results :)

James
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on January 27, 2016, 03:52:03 PM
James, I dont expect many to have success with DMSO applications as it is such a cumbersome and long term thing. Took me months to get into a working schedule and protocol to achieve lasting improvement.
And if you mention such applications to a doc Im pretty sure almost all will discourage as the two I met did with me.(but it helped more then any of what they proposed).
The whole Thackers "mystery" formula back and forth didnt help with DMSO's reputation too.

Hello Melting!
One can try the other methods with a success deemed here in the forum as useless. When it comes to the use of iodine it is also used in iontophoresis to soften connective tissue - scars, keloids, adhesions and bumps. Vitamin C can be used to effect elasticising walls of blood vessels, anti-inflammatory, and enhances the effects of immune system and additionally the use of acetic acid helps to dissolve calcium deposits by converting insoluble carbonates to soluble acetates - spurs, bony growths, periarthritis, myositis ossification's. All this doctor does not tell You :-)
Exactly! And Magnesium is the natural calcium antagonist.
If I remember right then copper can help too as it plays into some parts of our condition adn vit c + magnesium can create a copper deficiency(?). Cant remember how, and if so what version of copper to use(copper peptide?) I think I remember that I didnt use copper as it was too expensive back then.

MSM, a derivate of DMSO, can be eaten and is together with vit.c  usefull in healthy collagen(with our condition we have "bad" collagen).
But If I too remember correctly then the DMSO I apply will in my body anyway turn into MSM.

Any more ideas on what to combine with DMSO?
My formerly hard plagues/scars are all smaller and softened and I would love to get totally rid of them to avoid any flare up again.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Pey-penis on January 28, 2016, 04:09:33 AM
Hello Melting!
When it comes to the removal of calcium deposits I had a problem with heel spur, whose I get rid with the zapper or iontophoresis with apple cider vinegar 6% acidity (no alcohol) used instead of water.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: NeoV on February 28, 2016, 07:21:37 PM
Freemason, I'm curious if you ever got together a topical solution to try, any progress?

Melting what is your schedule these days and how is your progress?

Lately I am trying to get myself to attempt more therapies, even ones like DMSO, for a number of reasons. I find the DMSO story interesting because in theory, it should do something helpful, even though it has not helped many people here.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Bentupup on March 20, 2016, 09:29:38 AM
I just wanted to say that i had a 30 degree bend i have been using castrol and absorbin jr and have notice a great deal of difference now after 2 weeks i am down to about   15degree bend. It seems to be working some.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Gutted on March 20, 2016, 06:54:15 PM
Bentupup

Can you tell us a bit more please

"Castrol" ?? ..... castor oil ?

"absorbin jr" .... whats that ?

How were you applying, just massage, massage after heat etc etc ??

A result like that in 2 weeks is amazing !!

Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: lonelyboy on March 20, 2016, 07:27:13 PM
Hi all, I was just thinking earlier, what mechanism does Muse use to get through to the CC to deliver the prostaglandin? I don't mean the poke it in the urethra bit, I mean how does it penetrate from the urethra through the layers to the two corpus cavernosum?
Thanks for any insight.

Sorry wrong place, I'll start new.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Bentupup on March 20, 2016, 09:26:43 PM
Yes castor oil. Absorbine jr is used for muscle ache and pain i just rub the castor oil in then i use the dobber on the absorbine jr and dob it on.  Then  i wrap it up with a cut piece of ace bandage for about an hour.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Bentupup on March 20, 2016, 09:34:28 PM
If you look at the active ingredients in absorbin jr. You should notice it has acetone   which s is dmso medical grade. It also has other properties that aid anti-inflammatory.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Bentupup on March 20, 2016, 09:42:03 PM
I am not a chemist nor am i highly educated. I jist prayed and prayed about my condition. And the absorbine jr. Just came to me in the strangest way. And it is really working.  It is well wihin my budget for treatment
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Crooked_Stick on March 20, 2016, 10:27:30 PM
Bentup...can you tell us about any scar tissue, ie, plaque that you have and have you noticed any change using the casor oil and absorbine jr.? thanks....sounds almost too good!
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Bentupup on March 21, 2016, 07:11:51 AM
Would b more than happy to give testimony. It all started about 8u months ago while wife and i were having sex. We were over excited and and sex was getting rough and intense pleasure was soon interupted by a loud pop with little or no pain. I comment to her humorously i think i broke my dick. It was a day or two later i started to notice a slight bend in my penis to the left. Within a day or two there after i noticed a small lump on that side followed later by a second lump. I totally ignored the fact that anything was wrong thinking of it will heal. Later on seems the lumps had gone away but my penis was shrinking in size anfrom a long 10intime to a near 4inchs. I was imbarrassed and kept this this to my self. My sex drive had gone erection was near to impossible. I later 5 months googled broken penis and quickly diagnosed my self as as to haveing the disease. In the 5month the noduales had move to the lower top base of my shaft and a line up the top near total lenght. If and when erction was possible my penis was bent so bad it pushed into myself. I started reading. At first i would rub myself with vitimine e oil with unsatisfying results. I started my investigations with google reading all i could and was so confused about all the info. I started using caster oil alone and was getting no results but getting plenty sticky. That is when i started praying. And one morning i opened my med. Drawer and the absorbin jr fell in my hand i thought absorb huh i then looked up the ingredient and found that it included a lot off what i had read about. Acetone. Menthol hince, ment with alcohol. And many other oils of heeling like wormwood. Thinking this is Gods way of answering me i starting using it. I first started with the castor oil then would dab large amounts of the absorbin jr on.  It was a not so pleasent feeling but yet a pleasent feeling. I then started with cotton balls soakeditb ny ingredients
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Bentupup on March 21, 2016, 07:25:54 AM
Please excuse my typin skills. Part 2. I applied the cotton balls on the nodules and wrapped with a piece of ace bandage for 30about min. To an hr. Two times daily. As far the noduales the have shrunk from quarter size to dime size or smaller my penis is no longer pushing on me when erect about 2 incbes away from me. The noduale alone the top and lenght is about gone. Is it a miracle or the absorbine jr. Or maybe both you be the judge. I have also gained 2 .5 inches back. I think i will keep it up and maybe add a little apple  cider vinegar. Also pray to help with my spelling and typing. U ask and i will try to help. Love all and live all.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Bentupup on March 21, 2016, 10:16:46 AM
The active ingredient in Absorbine Jr.® liniment is 1.27% natural menthol. Other ingredients include calendula extract, echinacea extract, absinthium oil, acetone, chloroxylenol, iodine, wormwood extract, potassium iodide, thymol, water and coloring agents FD&C blue number 1 and
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Pey-penis on March 26, 2016, 04:47:23 AM
Absorbine contains ingredients of fluid Lugol, which I mix with DMSO and impose at the adhesions for 30 minutes. And it helps me to soften adhesions and stretch them gently but firmly. After almost 2 months already I have positive effects.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Bentupup on March 27, 2016, 06:11:55 AM
Why not try absorbin jr, dmso,apple cider vinegar, castor oil,and streaching what we got together what we got to loose but inches if it dont work.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: goodluck on April 02, 2016, 03:56:55 PM
Bentup Thanks for sharing your experience with something so simple as Absorbine Jr.

Just looking at the raw ingredients I would think it would be a good analgesic, anti-inflamatory and anti microbial.  Why or how did it break up scar tissue or placks?  Who knows, but the results are all that matters.  The iodine is the only ingredient in Thackers that may explain some of it.  I know calendula is softening on the skin.    The acetone is similar to DMSO as stated earlier.  Maybe someone much smarter than I can study this and understand why it would work.

What else is remarkable is the very short time in which you saw results.

Are you doing any oral therapies along with this?.  i.e. Ubiquinol, ALCAR, Pentox etc.  Have you been using a  VED?

Keep us informed as you progres.
Goodluck
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Bentupup on April 06, 2016, 04:11:18 AM
Good morning good luck, i am having great results from what i can tell this morn. I dont know if i am blessed,or what but sure am giving thanks to God. I must say what is on my mind and just pray what is working for me will help many. I first might let all here know i am a poor ole country boy... money is not a giving. I have very little funds for resources so I
Will have to do the best with what little i have. Now i never consider myself to be smart or stupid but i will tell u guys my program if you want to try it that is up to u. I will tell all u that i will be as honest as humanly possible ,i am seeing results. Remarkable results.  Poor man attempt. Ok i first rub the noles with castor oil.  Laugh if you wanna but i then take some pantyhose put a slip knot in it and slide it over the head and pull it snug. Then i take a ace bandage and tie it between my legs at knee level and pull pantyhose tight and tie it to the ace bandage. That puts a pretty good streach down pull on my penis. The noles are at the top base of my penis and run lenght ways alone the top. I then dob the absorbin jr on alone the top and base very generously. I then rub it in with pretty much forge keeping a tight streach on a little at a time by parting my knees. As i rub the noles i feell them breaking up i will rub them adding absorbine jr a couple of time for 30 min to an hr
i then take a peice of gauaze add absorbin jr to it and wrap it around penis then while streatched i wrap ace bandage around fairly firm but not cutting off blood suppy. Realease tension and leave penis wraped over night.  As far as scaring i really not noticing a bunch but this is what i do alone with prayer before and after. I am taking nothing orally that is all i am doing. Might sound hickish but it is making a diffrence. Sex is good and life is getting better. If you find this works for you then pass it on at light speed.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on April 11, 2016, 12:47:52 PM
Good report Bentupup, makes all sense.

The Absorbine Jr. possibly drives some of Castor oil into the skin too.

DMSO could possibly potentiate the penetrative effects.

Freemason, I'm curious if you ever got together a topical solution to try, any progress?

Melting what is your schedule these days and how is your progress?

Lately I am trying to get myself to attempt more therapies, even ones like DMSO, for a number of reasons. I find the DMSO story interesting because in theory, it should do something helpful, even though it has not helped many people here.

DMSO is cumbersome to apply and you need to do it often(daily every day) and much can go wrong (espacially skin wise, burning, very dry etc.; handling..) Thats a part why you wont get much feedback. But the ones that do can give you plenty as you have to get deeply into it(much reading etc.)

I have no negative effects from the plagues anymore. That said I never had a huge bend but mainly hourglasse effects.

I do pump often with warm and (ice) cold water(anti inflmmatory) and do apply DMSO from time to time to keep what is left of the plagues soft.
Im trying some application of DMSO into the urethrea while holding the penis off at the base at the moment. I hope to target some nodules that are near the urethrea(deeper) with this more easily. Sounds bad but is easy to apply once you get the hang of it. ( I do it with an glas eye dropper inserted into the urethrea)

Overall I increased the health and strength of my Penis so much that the nodules dont matter much. I do basicly many of the so called Penis enlargement exercises that are to be found around the web and forums(jelq etc.) In a way Im healthier then before the Peyronies Disease.
But be carefull anyone who reads this, if you have any underlying tendencies to get new peyronies plagues/nodules (inflamamtory problems) then any penis exercise might create new problems!(!!!)

Well, Im happy to not have done what the doc told me(cut them out)
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Bentupup on April 15, 2016, 10:51:45 AM
Good results this morning. The nodules is breaking up. I am pleased to say what i am doing seems to be productive. This to me is a God thing. Through prayer the absorbin jr. Just fell into my hands as i was praying for a answer.  I pray it will work for others as it helping I i am not pushing religion here. But he can do for us what we cant do for ourselves.  I think it might not hurt to up grade to absorbine jr. Xtra strenth or get a higher grade used on horses from the farm store. And i hear it comes in patchs to.              God bless all.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Freemason on April 20, 2016, 10:58:24 PM
Im gonna give absorbine and castor oil a shot..its Menthol as an active..doesn't it burn? I can see how it could work in theory as it certainly would penetrate the skin...hence the name absorbine..lol...interestingly using absorbine is an old home remedy for removing scars on horses back in he early 1900's. It's been around forever.  What the heck..why not.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Old Man on April 21, 2016, 07:57:41 AM
Freemason:

Yes, you are right about using Absorbine on horses ankles, lower legs as well as upper legs when they had problems with soreness and other leg maladies. It worked great, but the user had to be careful to take care when using it since whatever ingredient you wanted to penetrate to the pain they had, it would do the same for whoever was applying it.

I lived on a farm in the 1920s through the 1950s on a very rural farm area in the Deep South of the USA. We could not afford a vet to keep our farm animals healthy, so we used our own home remedies including a medicine similar to Absorbine. It was labeled as Horse Linamint in those days. It worked wonders on repairing our disabled animals.

The above is just my 2 cents worth of caution about using any supplement or med that has the ability to penetrate at least one or two layers of ones skin. Any substance mixed with the Absorbine would also be carried into the inner parts of ones Dick.

Old Man
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Bentupup on April 21, 2016, 06:14:06 PM
Freeman,old man
You are both right in my studies of the absorbin jr.  And yes freeman it does burn if it gets on the nut sack. Other than that it doesn't burn at all. I must say i like the ingredients in the absorbin jr on it contains some of the same ingredient as thacker formula  so if i were to add anything it would be apple cider vinagar. But the absorbine jr already has iodine that should be helpful plus it has natural antiimfamatory properties.  I haven't had a break o ut or skin burn yet but when it gets on the nuts it has potential to make you say oh my "God" as you show you teeth and try to create a wind tunnel to blow on you nuts. Lol. But old man has a good point do not add anything that could be carried into the blood system. I myself am thinking of alternating treatments with a pack made of meat tenderizer. But not with the a absorbine jr. Will see how that will work.                    Bless all...
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Arkibald on April 27, 2016, 08:12:54 AM
Bentupup,

This is my first post on Peyroniesforum. Thanks for your encouraging reports. I checked on the Dupuytren forum, if anyone there has tried Absorbin with success.

It seems to be the case, at least for the veterinarian version of Absorbin: Other therapies &rsaquo; Liniment/Vitamin E/Laser Pointer Treatment | Forum for Dupuytren's contracture (http://www.dupuytren-online.info/Forum_English/board/other-therapies/liniment/vitamin-e/laser-pointer-treatment-2_80.html) The writers refer to "Horse Liniment", and "pain relief liquid" from 1892.

Arkibald
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Arkibald on May 05, 2016, 07:29:44 AM
Bentupup,


Is all still progressing well?
I have ordered Absorbine Jr from the US and expect it to arrive within next week - ready to try your protocol:-)


Regards,
Arkibald
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Bentupup on May 07, 2016, 06:38:13 AM
Yes arkibald.  I am having great result. I am using the xtra strength version of the  absorbing  Jr  any questions and I will help what I can. I am gaining Inches back as I using my stretching and the nodules seemed to be getting softer. As I massage them while streaching I feel them break up till  they are down to hardly nothing. They will return daily but bust up more easily every nite. I will stick to my program for now.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Freemason on May 12, 2016, 10:50:57 PM
Ok so I started my first experiment with stuff two days ago...my curve is about 50 degrees dorsal..my plaque is cord like about an inch and half on top. So I bought SOD cream (super oxide dismutase) which has Vit A, Vit e and other stuff..I put that on my plaque first then use a q tip and put Absorbine over top 2x daily.  Wow the tingling is wowzer. But it goes away. This far I've not noticed any skin irritation..yet.  The SoD is 25,000 iu in the cream. I figure it will prob take a few months if I'm gonna notice anything.  I'm seeing my regular dr tomorrow and I gonna ask her to RX me 15% Veraprimil cream too to add to the mix...why not.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Bentupup on May 15, 2016, 02:08:33 AM
I start with the castor oil first my self then I pull a stretch using the panty hose and ace bandage while I have the tug put on it I then generously don the absorbing jr. I then  start rubbing the Noles as I can feel them breaking up. I will add the absorbine Jr a couple more times for the hour I streach. It is helping me and I ask my higher power to help others. I like the ideal of using the cream to. I use a generous amount of the absorbine Jr and never noticed any skin burns at all.  Together we can win. I am also thinking bromimene.  Or how ever you spell it but it is used in meat tendirizer. It is made from the stem of pineapples. Any thoughts on that will be grateful.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: krazylord on May 30, 2016, 10:36:23 PM
If I want to use DMSO + Castor Oil, what do you put first? I see here (DMSO and Castor Oil For Scar Tissue | Listen To Your Gut (http://blog.listentoyourgut.com/how-to-release-and-dissolve-scar-tissue/)) they recommend first putting DMSO, let it dry, and then castor oil, but that doesnt make sense to me.

ANy ideas?

Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: goodluck on June 05, 2016, 12:44:27 AM
I thought they were premixed together?
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on June 13, 2016, 10:49:31 AM
I start with the castor oil first my self then I pull a stretch using the panty hose and ace bandage while I have the tug put on it I then generously don the absorbing jr. I then  start rubbing the Noles as I can feel them breaking up. I will add the absorbine Jr a couple more times for the hour I streach. It is helping me and I ask my higher power to help others. I like the ideal of using the cream to. I use a generous amount of the absorbine Jr and never noticed any skin burns at all.  Together we can win. I am also thinking bromimene.  Or how ever you spell it but it is used in meat tendirizer. It is made from the stem of pineapples. Any thoughts on that will be grateful.

As per this usefull post: DMSO, DMSO based Solutions and TOPICAL Treatments - Peyronies Society Forums [Page 8] (http://www.peyroniesforum.net/index.php/topic,39.350.html)
Bromelaine, which I guess you mean, is too heavy. But who knows if parts of it can be absorbed..

Your whole absobine application + breaking up of nodules sounds good. Did you manage to do it until now?

I feel like the total dissolution of my plagues would depend on me doing a protocol everyday for months and maybe years. I did have results which keep me fully functional so I cant get the motivation up to get rid of all of it but I might have to for the future.

Whenever I did a protocol with DMSO I had to do it reguarly to improve. Whenever I made a bigger pause the plagues did get harder again needing some days and weeks to get them again softer / diminish slightly.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: overcomethis on July 24, 2016, 05:09:02 AM
Has anybody tried John Parks' DMSO formula? 

If you google "The Sexually Healthy Man: Phase 3: The Infantry Attack/Topical Gel", you can find all of John Parks' method there.

I'm considering trying the DMSO formula and heat therapy to improve my symptoms. 
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Perplexed on July 24, 2016, 08:41:12 PM
I have been using an ointment containing DMSO that has resolved nearly 90% of my peyronies plaque and I expect the disease will be totally resolved within the next month.  I am also applying the ointment to my hands to resolve Dupuytren's issues. 
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: QuackAttack on July 24, 2016, 10:04:34 PM
Overcomethis,

John Park is a scam artist. If you do your research, your can find him on a commercial for Xiaflex. It's on YouTube. John Park is about cashing in on people knowing full well how freaked out we get when we see something unusual with our package.  I tried it all, but never once bought anything linked from his site and none of it did a bit of good. The only thing that potentially did anything is traction, but not more than 5 degrees which isn't much when you have a 45-50 degree curve. I will say traction does give you stronger erections.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: goodluck on July 25, 2016, 01:05:26 AM
I agree, I would stay away from what ever Parks is selling.  He is a businessman first and foremost.

He has been invited to come on this board and join  but he is staying away.  Maybe because he knows his stuff does not work.

Perplexed, why not share with us the ingredients in your ointment?  Your news is quite remarkable!
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: LeeBee69 on November 21, 2016, 10:41:14 AM
Hey there bentup,

What are the active ingredients of Absorbine  Jr? I can't see the publish the info and I it doesn't look like it is available in Australia. Just wondering if your bottle/packaging has the details?

Cheers,
LeeBee
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: mischa on November 23, 2016, 07:31:48 PM
I've just started the vitE and DMSO regimen. Also Absorbine jr. What routine, times per day of each etc. has everyone tried with success?
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Pey-penis on November 24, 2016, 08:49:27 AM
I am using DMSO as a medium for transporting iodine to adhesions and it helps me and it is already used by me for a year, including massage and manual stretching after a compress with a mixture of iodine with DMSO. Everything I described in the thread "Alternative treatments."
I'v lost 3 cm and now it is only not all 1 cm to recover.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: mischa on November 24, 2016, 06:26:57 PM
Yes thankyou. I'm using it to help absorb of Vit E. Plus stretching. Massage I'm not so sure about. Seems there's more bad than good for development of edhesions. The concensus also believed that DMSO even on it's own is beneficial to breakdown of adhesions. I've lost a total of 3/4 of an inch in 3 weeks and girth where the hour glassing is. Frustrating!
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: LeeBee69 on November 28, 2016, 06:00:07 AM
How are you guys applying your DMSO cocktails? I know DMSO will carry anything small enough and am concerned about bleaches from cotton or nasties from other material.

Cheers,
LeeBee
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: NeoV on November 28, 2016, 06:24:17 AM
That is simply awesome Pey,penis!

Yes, DMSO ALONE will work to reduce scarring. There is plenty of literature on that.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: mischa on November 28, 2016, 05:12:09 PM
I wash my hands and apply with my fingers only.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: LeeBee69 on November 28, 2016, 06:04:29 PM


Thanks!
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: mischa on December 04, 2016, 12:45:26 PM
Some thoughts on Absorbine Jr. I have been using it alternating days with DMSO and Vit E on opposite days. That being said. Some have mentioned about burning on or off ball sack but not their dicks. I have been getting some pretty deep burning just on my dick lasting over 5 min. Now I started using the DMSO on top of the AJ and it seems to limit the length of the burning time. Maybe tempering it or getting it absorbed quicker?  Either way I'm a little concerned. I have been using Black Bottle,  a cream used to increase healing and restore sensitivity used for ED and general nerve response based on age, being circumcised and having your dick head rub on your shorts over a lifetime. Anyway was thinking maybe this is "allowing" greater response to the AJ as well as the E and DMSO applications. I would appreciate everyone's thoughts.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: peyter on December 15, 2016, 07:40:42 AM
Dear All,

Im gonna try DMSO with absorbine or iodine. I Will try and report to you. I will keep you postd. By this time Ive spent 2,5 months with E Vit + Clhrodie Magnessium and Ginko Bilova (this on added in last 2 weeks).

One question is if you can suggest how to buy it? any recommendation or comercial name? DMSO I mean.

thanks.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on December 15, 2016, 07:58:32 AM
Taking 99,99% quality DMSO is advised. I used the 99,5% for some time without problems though.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: peyter on January 01, 2017, 01:25:14 PM
Dear all,

I ve ordered my own cocktail regarding to all i ve studied and founded on this forum, just to share with you:

DMSO 99.99 %
Castor oil
Magnesium oil
Iodine concentrated
E vit oil

As i have nothing to lose before going to a more invasive treatmemt and for the time being i have a "normal" life i decided to try and see whats going on. I will start with all cautions and being so conservative and gently. I will keep you post if i feel good news.

One point is someone have tried contractubex or santyl collagenasse with DMSO maybe it can work in the same way...just to know your opinion.

Happy new year
Pey
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Paolo on January 01, 2017, 02:10:20 PM
Good luck peyter, remember to be scrupulous with hygiene and post any positive/negative effects of your protocol  :)
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: mischa on January 01, 2017, 03:22:01 PM
Peyter, What amounts of what are you using? Are you mixing equal amounts? Also, I do wrap my dick after application of the dmso with gauze only because I do use powder on my balls and don't want to absorb anything from that. Also have you considered transurethral Vit E or dmso. I have been doing this with a dropper. It can't hurt. And yes I'm careful about contamination. Also, your thoughts on not using absorbine jr. I wouldn't mix it with the others but what are your thoughts on not using it as part of your regimine?
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: peyter on January 02, 2017, 04:52:29 AM
Hi all,

Thats the cocktail I ve ordered. (As I post before). I will put first all except DMSO, and secondly will cover the same are with DMSO. Thanks for your advices I will be scrupulous with the Hygiene. I will probably use cotton to apply all elements and a dropper as well. I ve not decide the amounts of each element yet...I will think about it.

Anyway when I start I will keep you posted.

Any idea about contractubex and DMSO?

Best. Pey
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Paolo on January 02, 2017, 07:02:53 AM
peyter, Contractubex contains;
1. Extractum cepae
has anti-inflammatory and bactericidal properties and prevents the formation of excessive scar tissue. This extract is from onions.

2. Heparin
softens the tissue structure, has anti-inflammatory and anti-swelling properties, supports cell and tissue regeneration and is able to bind water to the scar tissue. It is a blood thinner

3. Allantoin
encourages wound healing and has a softening effect, promotes penetration through the skin and relieves the itching often associated with scar formation.

There is also a product called Merdera, which I believe is 'similar' to Contractubex and contains Active ingredients
Allantoin/Onion/Polyethylene Glycols/Water, Emollient Combination No.46

I don't know if colloidal silver might be useful, colloidal silver is very friendly to the beneficial bacteria’s and at the same time kills those that cause skin problems,it would seem a prudent addition harping back to my earlier message regarding hygiene

All the best with this and be careful  :)

Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Paolo on January 02, 2017, 07:05:28 AM
Correction to previous message it should be mederma  :-[
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: peyter on January 02, 2017, 08:27:53 AM
So...contractubex seems to be ideal to attack the plaques?...if you mix it with DMSO can it be tracked to the túnica? or closer?...sorry I know this is can be crazy...but I think Im gonna try...I will do it with a lot of caution for sure.

Thanks!

Pey
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: LeeBee69 on January 02, 2017, 03:13:51 PM
Isn't the efficacy of this going to come down to the molecular weight of the active ingredients in the Contractubex? See Pharmacology of DMSO (http://www.dmso.org/articles/information/herschler.htm) section B. Membrane Transport.

Cheers,
LeeBee
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: mischa on January 08, 2017, 09:05:14 PM
Question for all. I have been using E and dmso on my dick but I have also been using a dropper to put it directly in my urethra. No pain etc and no uti. Been careful. But....I've had blood on my urine. I have no bladder pain or any other symptoms so I wonder if things are just irritated and reacting too the dmso or E.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: QuackAttack on January 08, 2017, 09:11:20 PM
If you are sticking something into your urethra, you are bound to have bloody pee. I had a cystoscopy done years ago and I peed blood off and on for 2-3 days.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Paolo on January 09, 2017, 04:24:15 AM
This just sounds madness to me  :o  ???
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: LeeBee69 on January 09, 2017, 05:34:03 AM
Dude! I would not do that...you may create a blockage as well as the potential damage to the urethra. The urethra runs along the underside of the penis - if your plaque(s) are on the top then you would be administering to the wrong place...

Cheers,
LeeBee
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: mischa on January 09, 2017, 10:28:32 AM
No need to be a smart a** lol. I am kidding! But don't knock it till you try it.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: mischa on January 09, 2017, 06:21:51 PM
Old man

I hope you know I really was kidding.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on January 12, 2017, 06:46:30 AM
Question for all. I have been using E and dmso on my dick but I have also been using a dropper to put it directly in my urethra. No pain etc and no uti. Been careful. But....I've had blood on my urine. I have no bladder pain or any other symptoms so I wonder if things are just irritated and reacting too the dmso or E.

I have done that and clamped off with my hand at the base of my penis. This way it did not move into the body. I basicly did hold it inside and after some minutes let most of it pour out.
If you used pure dmso + vitamin E then the chance is high that you burned the tissue a bit. I would always premix the dmso with at least some water(best distilled water). At least 5 parts(up to 50/50) water to 95 parts dmso. 
If you premix with some water you will get a heating reaction of the solution. With this step you take away this heating reaction from happening within your body instead.(reacting with the water in your tissue instead)
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: mischa on January 12, 2017, 12:19:18 PM
Melting. Thanks for the suggestion. I just hadn't thought that through but it makes sense
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: peyter on January 27, 2017, 08:14:53 AM
Hi I have all my DMSO+Cocktail. All arrived 1 week ago.

So Im gonna start this weekend.

I have: DMSO, E Vitamin oil, Iodine, Castor oil, Magnessium oil, and contractubex.

First I will mix all things except DMSO and contractubex. Secondly I will mix DMSO + wáter in a 70/30 % (in order to avoid strong reaction on my skin). I will apply topically first mix and after  the rest of things (DMSO and water) above. I will try that way for 2 weeks. I will apply contractubex separately. I will try to add more DMSO with time.

I will keep you posted.

Pey
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: mischa on January 27, 2017, 04:26:30 PM
Sounds like a nice start! I will say that I have used 70% DMSO out of the bottle which can be purchased as Pharmacy grade without any skin reaction or difficulties. This way it's not necessary to cut it with water.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: peyter on January 30, 2017, 05:06:29 AM
Dear all,

I ve started the DMSO treatment last weekend. As I said I mixed DMSO + Water in 70/30 solution.

Well, its not easy to apply topically exactly in the plaque área of my pennis, and by the time being way I apply only E vitamin oil and magnesium oil together and after that y put some DMSO drops above in the same área wirt the eye dropper. I dont feell any skin reactions for now and all its seems to be ok. I cant say more because It will take some weeks to notice any changes (If I have luck), but I can feel my pennis a bit soft on the skin...just my perception.

I will probably mix all the components together + DMSO 70/30 on the second week, and apply it topically, and we will see what happens. Maybe on third week I will try to use DMSO 99%, depending on how it Works on my skin, but no problems for now.

I will keep you posted.

Pey
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: kuaka on January 30, 2017, 12:46:58 PM
Just be certain to use only your bare hands to apply.  The DMSO will pull latex from latex gloves into your skin, which is not something you want.  Not sure how it reacts with other materials, but if you err on the safe side... 
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: dplookin on January 30, 2017, 01:37:35 PM
Peyter............have you considered using the DMSO Gel with Aloe ?  It is 99.9% and easier to use than the liquid DMSO.  You can apply your Vitamin E, Magnesium, etc and then rub it in with the DMSO Gel.  Aloe is also a softens, if I'm not mistaken, and Aloe is a Healer.   Just a Suggestion.  dplookin
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: peyter on January 30, 2017, 03:28:33 PM
Thanks kuaka and dplooking...

For sure I apply the dmso with my washed and bare hands just let it down from the eyedropper above the area of the plaques, i think so. Thanks for that point.

I think i will mix all components together and apply it in one solution, it can work properlly, i will tell you next week.

I decided to go for a 99% liquid dmso because maybe is a more pure formula...but why not to try it...i will have a look on internet about dmso gel, thanks!!

Pey
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: QuackAttack on January 30, 2017, 11:19:43 PM
Peyter,

Be very careful with the 99% DMSO. You can completely dry your skin out and get quite an irritation. More or higher % isn't necessarily better. Go with the 70% DMSO Gel and use very little. A very small dab is more than enough. If you use more than 1/16th to 1/8th of a teaspoon, you are using too much.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: peyter on January 31, 2017, 11:51:54 AM
Thanks Quack and all guys!!

Thanks for your advices. Ok, I will. For now Im just applying topically a 70/30 DMSO/wáter solution above the other components (E vit Magnessium oil iodine...). First of all, I did some trials on my hand with differents percentages of DMSO diluided in water. I just feel a bit of skin warm but no reaction and no pain, same on my penis...(good to know...;))

Lot of thanks for you interest and advice. I will report trials on my to all people interested to know. Im being so careful for sure. Its soon to see any results but I dont feel bad. Im on the first week.

Regards
Pey
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: NeoV on February 01, 2017, 05:36:22 AM
Can't wait to hear about your results! Good luck : )
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: peyter on February 06, 2017, 11:01:00 AM
Dear all,

first week was ok. No pain, No reaction...some warm sometimes during the application.

Yesterday I mixed solution which consists in DMSO + water 70/30 + Evitamin oil + iodine. I apply Magnessium oil and contractubex before with my fingers and after that the solution I wrote.

I just feel my penis a bit soft on the skin and my plaque as well, but I cant say there is a noticeable change on it. I only can say for the time being Im gonna have a soft skin penis, we will see If the plaque inside gonna be more soft in next weeks.

I think is better to mix all components together, easy to apply topically, only thing is that Im not mixing the contractubex (is a gel) neither magnessium oil (Is a bit reactive).

I will keep you posted next week wiht the new solution.

Pey

regards
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: mischa on February 06, 2017, 03:18:30 PM
I have been using my topicals for about a month with little if any change. I have also been using the E transurethraly. Can't hurt but thought inside and out may be more effective.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: peyter on February 12, 2017, 02:11:51 PM
dear all,

Finishing 2nd week. All is going ok. No skin reaction. I just feel a bit soft in the skin and maybe in the plaque. I keep on applying topically the solution I told...

Im gonna increase a bit the DMSO % maybe try 80/20 DMSO/WATER and mix with the rest of components. I think its definetly better to apply all stuff together in one solution instead in a sequence. Im gonna increace the % of iodine and C vitamin as well.

I apply the mix gently on my penis and wrap it with a gauze before going to sleep.

Well thats all for now.

I ll keep you posted.

Regards.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: peyter on March 09, 2017, 11:49:59 AM
Dear all,

Still working on it. I've finally decided mix all together and apply it directly to the skin every night before going to sleep (DMSO, E vit oil, iodine and contractubex). I cant notice important changes for the time being and all remains in the same way. I just can feel my plaque a bit soft but this effect is not noticeable when erection occurs and the curve is still the same...

In last week I ve added and Ultrasound (1Mhz) Sessions alternative days (15 min) and we will see whats going on in next weeks.

As well Im gonna try PF traction device, but I preffer wait for a more softened plaque to do it.

To be continued...I will keep you posted.

Pey
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on March 13, 2017, 08:40:37 PM
Good reporting Pey. Attacking the bad tissue from different angles seems wise(like adding the ultrasound).

Its annoying to think it might all be done for nothing but there is no fast solution that melts the plague away from one day to the other.
I said several times that when I applied the different solutions I felt an improvement of the situation and softening of the plague. But whenever I stopped it seemed the plague got harder again. I can only assume it lost some if its size through the DMSO applications.

The apply was always a pain in the a**. Applying some castor oil over the dmso+x solutions was nice when you didnt have to wear clothes(sticky). It seemed to seal it off nicely. Also white 100% cotton clothes full of the solutions and then "plastic wrap" was nice. (Heal Yourself At Home (http://archive.is/or50A) check this!!! use the right plastic wrap or you could poison yourself!!!)

As I had severe hourglassing I never had to deal with the curve problem. I combined the DMSO applications with pumping(+ added heat) and extending and later so called Penis enlargement exercises. In essence I created a stronger dick around my plagues while softening them with the DMSO. They are still there but dont affect me anymore. Be aware that in doing pumping and extending you have to make sure that any underlying inflammatory conditions arent still present or the condition could aggrevate.(best dealt with in a healthy lifestyle/food). Good thing is DMSO itself is antiinflammatory.
Im pretty sure that DMSO+x application alone wont be curing it in most cases. Maybe in the early inflamatorry stages when it is still forming.. but when its a calcified hardened plague there needs to be at some point a carefull stretching or inflating action. 

IMO: DMSO+Iodine is good to combat inflammation and early stage.
DMSO+Magnesium and DMSO+Vitamin C is good to soften the calcified plaques who presumably are mostly calcium kind of scarlike tissue.

It is complicated and hard to proof but I think DMSO+x has some advantages vs. eating tons of supplements. One could still do that to help the cause but I question how these vitamins etc. get to the plaques. I think they already sit at a relativly bad position where not much blood circulation is going on. Its kind of a trapped inflammation that gets encapsuled then by scar tissue. The tunica isnt that much flooded by nutrients like lets say a shoulder or elbow.
DMSO for sure will get stuff inside. How much directly to the plaque we cant know. I assume the more the better. If you could throw the plaque in a glass of DMSO+ascorbic acid it would be interesting ;).
For me clearly doing the application often did soften the tissue not only superficial but also inside effecting the plaques. Stopping it seemed to hardened them again.


To suggest a protocol for hardened plaques(out of the initial stage):
-Daily applications if maneagable. If possible even twice a day or more often.

-Mix medical grade DMSO(99,99%) in a glass jar 7 parts with 3 parts of X. The Glass jar should be one from the pharmacy with a glass eye dropper and no harmfull plastic parts that the DMSO could melt away.(Heal Yourself At Home (http://archive.is/or50A) -plastic guide!)
-X might be: 1. Ascorbic Acid(vitamin C);2. Magnesium(Magnesium Chloride); 3. Vitamin E(Im not sure which is the best version-google);4. Castor Oil(cause castor oil has many vitamins and helpfull stuff in it that the DMSO will react with); 5- Iodine(I used the rather expensive nascent iodine)
X could be anything that is deemed helpfull in attacking peyronies condition but needs to be of certain molecular weight(reference DMSO, DMSO based Solutions and TOPICAL Treatments - Peyronies Society Forums [Page 4] (http://www.peyroniesforum.net/index.php/topic,39.msg20335.html#msg20335) )

-Apply solution all over your Penis and especially where the plaque sits. Make sure to be clean and be aware of how to handle DMSO(no poisonous chemicals near it and over your skin after application,- including coloured clothes.)

-Cycle the solutions and make sure to not burn your skin with the DMSO. Aloe Vera gel helps and test on skin.
I would use Vitamin C solution the most cause it is rather fast metabolized. 3 applications Vitamin C, 2 Magnesium, 1 Iodine, 1 with all in one.
The DMSO+Castor oil solution could be used after any solution on top and also overnight as the castor oil is good for skin and might penetrate over time.
Im not sure on mixing them all together. This might be done too but as an extra bottle and application so to speak. Observe what seems to work.
keeping the skin healthy and avoiding DMSO burns is important cause otherwise you might be forced to make a prolonged pause to heal skin.

-If you are able to then do lightly stretch your penis with your hands against the curve after and/or during application.
Or look into using Extenders and/or Vacuum pumps.(Keep care to not injure yourself further, this needs much tuning into yourself in what is good and what not)



-Eat and live healthy.
-Be aware about what you do with your Penis. Keep it healthy and working(erections are good. bad masturbation habits are not. Be carefull during intercourse with artistic positions)
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: peyter on March 21, 2017, 09:45:51 AM
Dear,

Im still on it. By now increasing DMSO % on the solution, adding iodine and E oil vitamin and magnesium oil as well. I ve added Ultrasound sessions 2 times per week. I will add C vitamin next week...I gonna check. In one month with a bit soft plaque I will add a traction device.

I feel the plaque a bit soft...but just a bit.

I will keep you posted.

Pey.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Christopher1 on April 09, 2017, 03:49:12 AM
I used pure DMSO, and it made my penile skin look 20 years older. This change is unfortunately permanent.

No improvement for my ED or Peyronies Disease. AVOID DMSO!
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: ConstructionHero on April 10, 2017, 11:49:53 AM
Hi, I'm John Parks, and I did not originate this formula. My Dad read about it on Dr. Johnathan Wright's (Tahoma Medical Clinic) website, where he discusses DMSO for different scar and collagen disorders. I used this formula on myself, but also used a hot compress first to heat up my penis, increase circulation and to help soften the scar/plaque.  I used hot washcloths, since a heating pad was either too hot or not hot enough. I then applied the DMSO/Iodine/Vitamin E.  I didn't massage it in, but just rubbed it on, covering all of the penis, including the glans, and then let it soak in.  I had skin irritation when I rubbed the DMSO too much. I never found one source for everything, I used ........ 70% DMSO, ....... Iodine/SSKI and the Vitamin E were just small gel caps that I broke open.
I also was using Traction and supplementing with enzymes, Acetyl L Carnitine and L Arginine/L Citrulline.  So my results were great, but my results are also anecdotal, since I was using multiple treatment methods at the same time.  It is not like a double blind placebo study that is truly scientific. My wife and I are very happy with the results.  My curvature was almost 90 degrees, and after 12 weeks it was around 10 degrees.
Brand names removed by moderator
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Christopher1 on April 10, 2017, 03:42:53 PM
Can you still feel your scar/plaque?
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: QuackAttack on April 10, 2017, 10:39:00 PM
I am going to call BS on John Parks. About a year ago I watched a video from the manufacture of Xiaflex and low and behold who was there, none other than John. Used car salesman. Don't buy anything from his site. In the video he does speak about having an almost 90 degree curve and how Xiaflex treatment worked for him. As a person that has undergone 4 cycles of Xiaflex, I can speak to its effectiveness. I have had about 20 degrees improvement. When I first found out about the stupid condition, the first website I came across was John's with all of the stuff he puts out there. Being a skeptical person, I wasn't going to buy from just anybody on the internet. So, I bought most of the stuff he was pushing, but from the manufacture for less than he sells it. AGAIN, can you say used car salesman!!!!!!!!!!

You have been OUTED!!! Nothing I despise more than a scam artist.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Christopher1 on April 10, 2017, 11:20:49 PM
I find it hard to believe DMSO can reverse scar tissue. Studies?
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Paolo on April 11, 2017, 02:46:25 AM
Ditto with QuackAttack!
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on April 13, 2017, 04:55:36 PM
Yeah whatever the guy achieved is discredited. He wants to make money offering nothing we already know.
Still no reason to put down DMSO along with him.

Christopher1, pure DMSO is NOT advised. I know the condition that is created from doing too high %. It dries the skin. But it will surely go away especially when you use some healthy mosturizer(for example castor oil).

The properties of DMSO are known and can be used to attack peyronies.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Christopher1 on April 14, 2017, 12:33:29 AM
It damaged my skin.

Seems permanent. : /
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Christopher1 on April 14, 2017, 12:41:21 AM
How will the castor oil improve my damaged skin? I seem to have lost a lot of natural turgor since the DMSO, sadly - a sign of aging.

I am curious why castor oil in particular.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on April 15, 2017, 05:42:30 PM
I burned my skin with DMSO once and it then pealed off for some days until new skin appeared. Castor oil helped me.
I can imagine it taking some time to heal. I cant imagine turgor totally gone forever.
How long ago was it christopher? Is it just getting worse or is there any improvement? If there is an infection to the skin apply some cortisone lotion/cream.

Castor oil stays rather sticky to the skin and coats the skin nicely moisturizing it. Its like a second skin so to say.
It softens the skin nicely if applied overnight or long duration. Take care with clothes as it stains them.
The parts in it can replenish the skin it seems.

[If you ever do dmso again use it mixed in at least a 70/30 ratio. It truly has great properties but will burn skin if applied in undiluted strength.
If you take the dmso and mix it with some water it will have a heat reaction(which happened unfortunately in your skin now). Applying it after diluting wont create the reaction on the skin then.
Actually mixing it in a concentration like 10% with castor oil might improve your condition driving the ingredients of the castor oil deeper.]
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Christopher1 on April 16, 2017, 12:18:03 PM
I will give it another try.

Thank you!
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on April 16, 2017, 04:52:37 PM
DMSO needs to be premixed with water or another aqueous solution before applying to skin.
DMSO + water creates a heat reaction. If undiluted DMSO solution is put on skin the DMSO will react with water in the skin=burn.

When DMSO is advised people often say its 99% which means the quality of it.
Use 99%-Quality DMSO and mix it with water 50/50 up to 90/10.

Also dont mix with chemcials on skin or any other harmful substance as it will carry into skin.

Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Christopher1 on April 17, 2017, 02:00:47 PM
I did not know it was an exothermic reaction.

Interesting stuff.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on April 18, 2017, 04:47:27 AM
DMSO is quiet an interesting substance.
It "freezes" above 0°C.
It plays with the lipid layers of the skin which are normaly not penetrable for most substances.

There is a lot of mumbo jumbo talk about it on the web but also a huge amount of detailed science.

http://www.sciencedirect.com/science/article/pii/S0006349507714601
"The simulations also reveal that at high concentrations DMSO can induce water pores into the bilayer, which may be an important mechanism for permeability enhancement of solutes."
Couple this with the exothermic reaction and you have a good "burn". As it goes so deep the "burn" is also deep and not just the upper layer. Not in a fire type burn but in this weird way of displacing.
Half of my skin was peeling off for days like a snake skin and looking old and wrinkled.
I can see how it would scare you off from using it ever again.

But yeah in concentrations below 90% coupled with some afterwards skin moisturizing nothing bad happens at all.
Daily applications(which I think are needed when targeting the scar tissue) necessitate some skin care. Aloe vera and Castor oil are my favourites.

The only solution that was even at lower DMSO% a bit stingy was when I mixed it with Iodine.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Christopher1 on April 18, 2017, 06:41:23 PM
Interesting.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: kuaka on April 18, 2017, 10:17:58 PM
I'm about to try something.  I have ordered some liquid bromaline.  My plan is to mix it with DMSO as a carrier.  Wrap up for 15-20 minutes...cotton wrap should be ok, no latex or other exotic materials which the DMSO will suck into me.  Follow that with a VED session.  I plan on doing this once a day for a while.  If it appears too help and not hurt, I may up it to twice.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Christopher1 on April 19, 2017, 01:23:50 AM
Bromelain - a pineapple protease - will digest all peptides.

I would not do it. Sounds like a disaster waiting to happen.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: skunkworks on April 19, 2017, 04:38:33 AM
Didn't notice this post earlier, I hope Kuaka has not tried this yet. This does not sound like a good idea at all.

You'd be using DMSO to allow an enzyme that digests protein to penetrate into your penis. Best case it does absolutely nothing as it's a pretty big molecule. Worst case it could cause you serious harm. Natural does not mean safe.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: melting on April 20, 2017, 12:12:31 PM
Bromelain is too big of a molecule.
Other then that your idea is good. Combine with some other stuff like vitaminC,vitE or magnesium.(lots of info in this thread)

Make sure to warm up the VED with a heating pad(for example). Heat gives more expansion.
Also make sure that if you have DMSO on your skin that it doesnt come in contact with plastic from the VED or similar.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: kuaka on April 25, 2017, 03:15:32 PM
I've been researching injectable Bromaline for Dupreyne's...I'll do a lot more research before trying anything.  Right now I have ZERO time to devote to ANYTHING, so NOTHING is happening on this front.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: peyter on May 10, 2017, 04:52:26 AM
Dear all,

Did a lot a of efforts to try dmso and combined components applied to my penis skin in last times.
I ve been trying since january.
Dmso + evit + iodine
Dmso 70, 80, 90 % by itself
Dmso + castor oil
Dmso + contractubex
Dmso + all mixed together...

No improvements for the time being. My curvature has been progressing till an stable state.

Thats my personal feedback. I hope it has worth for anyone.

Im going to have a xiaflex cycle to stop or improve my condition.

Best for all
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: james1947 on May 11, 2017, 12:37:35 AM
Thank you for the report peyter :)
I am not trying to convince no one that DMSO is not working.
Hope some people can learn from your experience ;)

James
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: pey ron on May 11, 2017, 05:21:48 PM
Dmso + evit + iodine

@Peyter: what is evit???

I seem to be having good success with DMSO + iosol + PABA and ALCAR both to saturation and magnesium chloride flakes, followed by the Thacker's Formula to rinse out the red stain from the iodine. I don't remember the exact proportions, but I tried to maximize PABA and ALCAR and only later add the magnesium chloride and the iosol.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Christopher1 on May 13, 2017, 09:54:57 PM
Probably vitamin E.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Spika on May 15, 2017, 12:29:13 PM
We might be having news  soon -from a reputable source-that will lead us to the right path...

I have contacted and spoke with, the Chief Science Officer of a Canadian Bio Medical Company.

They have a product (applied on the plaque) that they have finished Phase 1 clinical trials, and they are ready to start Phase 2.
The results so far are good.. The name of this product is known to this forum.

He is  open to the idea of contacting a separate and parallel Phase 2 clinical trial from this forum's members.

He will discuss it with the board this week and he will let me know.

Please stay tune...

Just in case that I get many PM and my box gets full, my email is: spi.kal@aol.com
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: pey ron on May 15, 2017, 02:24:22 PM
@spika: how is their product related to DMSO?

other than that, i'm definitely interested in being part of a trial
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Spika on May 15, 2017, 04:41:22 PM
@ Pey ron

Please either PM me, or email me : spi.kal@aol.com
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: peyter on May 16, 2017, 09:08:35 AM
Probably vitamin E.

E vitamin oil...its nice.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: peyter on May 16, 2017, 09:14:03 AM
Thanks to all.

On my personal case today i have no improvements by applying DMSO. I hope otther can have success.
I have to say i have no damage on my pennis and all products are ok...to do trials and never give up is on my way to face this condition...nex step for me will be xiaflex. I will report about it in the main thread on this forum.

Best of lucks
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: JayGould on June 18, 2017, 11:57:09 AM
Anyone tried hydrocortisone cream? Any possible negative side effects?
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: PTalk on July 01, 2017, 06:49:40 AM
Hi all,

I've had peyronies for about 3 years now and still have constant pain especially after anything sexual which can leave me with burning pain for days.  At 28 it's kind of destroyed my sex life.

I'm on Pentox & Ubiquinol, but a user informed me that he had the following DMSO based ointment made up by a compounding pharmacy - I am hoping you guys can help me fill in the blanks here so I can take the exact %'s / amounts required to my doc, and he will write the prescription for it.

"The active ingredients in the ointment I used include Verapamil 10%, Pentoxifyline 0.5% DMSO (don't know the percent) and the inactive ingredients lipoderm, vitamin E, and iodine.  The ointment is topically applied to the affected area twice a day."


As you can see I have the %'s for Verapamil & Pentox, however the DMSO and inactive ingredient %'s he did not know.  Anyone here have any suggestions on what would be a suitable % for the DMSO & other ingredients?

Basically just want the exact compound written down so I can get it made up - taking the list as-is to my doc would mean he would be doing "guesswork" for the DMSO and inactive ingredients - I figured you guys here may be able to help determine a proper % for all of these since you all know a lot more than most general doctors.

Also, what do you think of that compound mix?  The guy who provided me with it said a local naturopath had it made for him and it greatly reduced his plaque & bend by 90%.  My condition is different in that most of the left side shaft is affected and I have some cord-like structures as well, plus the constant pain which he did not have - nevertheless I think this could be a really good option since applying castor oil by itself doesn't really help me that much.

Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Paolo on July 01, 2017, 08:47:26 AM
Hi Ptalk, You should be taking ALC, it will/should help with pain  :)

There was talk some time ago about a mix called H-100, it consisted of a composition of combinations of calcium channel blockers (for efficacy)  nicardipine, verapamil, nifedipine, diltiazem, amalodipine, felodipine, isradipine, nimodipine, nisoldipine, bepridil, or a combination thereof along with superoxide dismutase (SOD), and emu oil plus suitable co-enhancers.

Patent EP2804606A1 - Topical therapeutic formulations - Google Patents (http://www.google.com/patents/EP2804606A1)

Hybrid Medical | Treatment for Peyronie's Disease (http://www.hybridmedicalmn.com/)

It unfortunately hasn't been trialed yet, but you could see what your Doctor thinks of it and he may help.

The variety of treatment options for Peyronie's disease is testament to the serious need that remains for an effective treatment

Peyronie's disease may develop following trauma to the penis that causes localized internal bleeding, and can result in painful erections and penile disfigurement. The physical structure of the penis includes the corpora cavernosa - two erectile rods, the urethra - a conduit through which urine flows from the bladder, and the tunica, which separates the cavernosa from the outer layers of skin of the penis. Peyronie's disease can involve the formation of a plaque or scar tissue between the tunica and the outer layers of the skin (e.g., subdermal scar tissue).

Erectile dysfunction due to fibrosis is common after 40 years of age, while the capacity for erection often is not changed. Because fibrosis underlies certain forms of erectile dysfunction, an effective topically applied antioxidant and/or calcium channel blocker formulation can be useful in treating forms of erectile dysfunction that arise from fibrosis
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: PTalk on July 03, 2017, 05:25:13 AM
Hi Paolo,

Thanks for the reply.  I have ALC plus all the rest of the supplements under the sun for Peyronies (haha!) although I've been experiencing a lot of hair loss lately (150-200 hairs a day) and knowing that some of those supplements increase testosterone in the body I'm worried that a few years of taking things like ALC or Acetyl-L-Carnitine etc. have brought it on or accelerated things.  That's why I'm stopping.  I also relied heavily on Celebrex which is a powerful NSAID which was very helpful for the pain - I would take it a few times a week but I now know an uncommon side-effect is hair loss, so I've stopped taking that despite the increased pain levels.  I digress.

Those are interesting articles, thanks for those.  I will look into these further.

In relation to the compound I listed above, could anyone or yourself offer some advice on what would be a good % mix for the missing % ingredients?  Furthermore, if you think it would be effective?  I feel like the Pentox and Verapamil (plus the others) in DMSO form could be really great.  Especially when combined with oral Pentox etc.  The guy said he had great results with it hence why I'm looking for some comments / advice on correct %'s.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: kuaka on July 14, 2017, 04:50:20 PM
I got zero relief from celebrex for my joint pains.  Have you ever tried Diclofenac?
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: JayGould on July 17, 2017, 01:36:18 PM
In relation to the compound I listed above, could anyone or yourself offer some advice on what would be a good % mix for the missing % ingredients?  Furthermore, if you think it would be effective?  I feel like the Pentox and Verapamil (plus the others) in DMSO form could be really great.  Especially when combined with oral Pentox etc.  The guy said he had great results with it hence why I'm looking for some comments / advice on correct %'s.

Ask him who the Doctor/naturopath was who prescribed it to him. If you find out the Doctor's name I will try to find the formula for you.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Paolo on July 17, 2017, 02:55:10 PM
Meanwhile I have e-mailed Hybridmedical asking on how H-100 specifically for Peyronie's use is progressing, I will share any replies if received, whether positive or negative :)
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: JayGould on July 17, 2017, 08:25:01 PM
Wondering how to get Magnesium and Vitamin C into the DMSO solution. Do you just crush a pill and mix it with the DMSO, or do you purchase topical Vit C/Magnesium?

I think I may try Verapamil mixed with DMSO too, and why not Pentox and Cialis too.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: pey ron on July 21, 2017, 02:53:29 PM
Where do we find pentox and verapamil in powder form? crashing pills and dissolving them in DMSO will get a lot of the caking agents in solution as well... Unless we find a good and very specific solvent first to get the active component out of the pills and then add the DMSO later after having taken out all of the precipitate...
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: kuaka on July 25, 2017, 11:54:35 AM
Something to consider when working with vitamins.  Commercially produced Vitamin C is ascorbic acid.  Vitamin C is much more than ascorbic acid, which is only a small part of the actual vitamin.  This is also true of D.  The commonly available D3 is actually a hormone, and not a vitamin at all.  For ANY vitamin supplementation, source a natural, whole vitamin.

Most of us are magnesium deficient, which contributes to all fibrosis conditions among many other modern health conditions. 

Magnesium supplements to avoid are:
citrate
ascorbate
carbonate with citric acid
aspartate
glutamate

Magnesium supplements to use are:
Chloride
Glycinate
Malate
Oxide - small amounts are ok, but still not great
Sulfate - epsom salts...soak in a bath
Taurate & orotate
Threonate

Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Tsanchez12369 on July 28, 2017, 10:38:10 PM
Hello, can you provide any instructions on how you prepare and apply these ingredients?  Thanks!
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: goodluck on August 14, 2017, 06:17:46 PM
Kuaka, Can you provide any insight in to why those forms listed as bad are bad and why those listed as acceptable are good?
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: kuaka on September 11, 2017, 10:47:59 AM
There is a chemical dance involving Iron/Copper/Magnesium which is way out of kilter in people who eat a Western diet.  There is more to a mineral supplement than simple bioavailability.  There are cofactors involved and an overall process of using Magnesium in the body which works better under certain circumstances.  Some forms of Magnesium are not very available, like Oxide.  Other forms include compounds which are themselves undesirable, such as citrates, aspartates and glutamates.  Most of "our" (those who eat a Western diet) Magnesium is "burned" to bind up excess Iron as well.

There is much more to how the minerals, vitamins and cofactors (other compounds used to process) than is taught or "generally accepted" in the west. 

As an example of how off we are, Ascorbic Acid is legally defined as Vitamin C, but that is only one very small part of the actual Vitamin C molecule.  It is easy to detect, and easy to synthesize, so we do...but it is like taking the box of food and eating the box without the food.

If you want some heavy reading, pay a visit to gotmag.org. 
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Tsanchez12369 on September 11, 2017, 11:34:04 AM
What about all topical: DMSO +  diclofenac + verapramil + xiaflex?
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Dorian Gray on September 12, 2017, 01:18:16 PM
Burning pain after intercourse may mean compression of the dorsal nerve of the penis by the plaque. Worrying condition.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Steveo on September 12, 2017, 08:17:20 PM
I'm not sure why these voodoo topicals are popular when people could be spending time and money on VEDs and Traction, which are proven to work (and which I have seen work on my own dong).

I've done the DMSO, the SSKI, the Castor oil, all that meaningless crap.  All it did was waste my time and money when I could have been doing meaningful therapy like stretching, heating, massage and pumping.

Don't waste your time with this stuff.  Applying DMSO and hoping that it causes some other substance to penetrate the outer layers of your penis and then magically heal your internal scars is nonsense. These witch doctor scams aren't going to do anything to remodel the scar tissue in the penis.  Sorry, they just aren't.  Only mechanical means will help. 

Even Xiaflex, which does dissolve certain parts of certain scars (if injected perfectly) requires the patient to mechanically bend the penis in the opposite direction while it's working.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: QuackAttack on September 13, 2017, 05:33:46 PM
Stevo,

I am going to back you 100% on this. I tried all the stupid rubs and they are worthless. Xiaflex and traction is the way to go in combination.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: kovasis on October 13, 2017, 05:33:24 AM
Well, stretching, heating, massage and pumping also sometimes reported to be the reason of making the condition worse...

So even that should not be stated as the "better" solution , besides DMSO is no crap , but this condition is crap.

I've already postet it in another answer of another thread.

As soon as someone reports a possible solution , this solution will be destroyed , or at least the pro's and con's turns it out be with no Effect in the majority of the cases, they were used...

The Reason why we all are here is that currently literally NOTHING REALLY helps.

I dont really see a light in any direction , so i wouldnt say this is better or that is not.

Simply face the fact that this disease will stay a miracle as soon as someone (in 50 or 100 Years) maybe really understand it and thus may have a cure for it...

Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: dplookin on October 13, 2017, 10:33:41 AM
Kovasis............I tend to agree with you.  I've done all the topical stuff, and I have done Traction for 7 or 8 months, and I've used a VED for 7 months, and I still have only 3 inches with a 90 degree bend to the right.  No, I did not start with just 3 inches.  Originally it was only 6 inches.  I saw one Urologist, and he didn't know what to tell me.  He couldn't find any plaque.  So what is the Real Answer ?  I hate to think of how many years it has been since I had a sex life.  Good Luck to You.  dplookin
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Tsanchez12369 on October 13, 2017, 03:19:03 PM
Dp,  r u considering xiaflex?
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Tsanchez12369 on October 13, 2017, 03:19:36 PM
Oh, and pentox?
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: dplookin on October 13, 2017, 04:03:50 PM
Tsanchez12369.........Thanks for your response and suggestions.  I tried Pentox...........Not Good, Bad Side Effects.  And about the other stuff, I am having a problem getting enough attention from an Urologist.  I am using the Veterans Hospital for my medical needs and they are constantly changing the Urologists.  This makes it difficult to keep one Doctor's attention to my problem.  Some of them don't care.  Not sure what I'm going to do.  The Problem is Depressing (as everyone knows it is).  dplookin
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: Tsanchez12369 on October 13, 2017, 07:28:08 PM
Dp, since xiaflex sounds like not much of an option...although I would insist...u might give pentox another consideration.  Most side effects can be addressed and possibly eliminated w another med like anti-nausea or anti-diahrreal, of course depending on what side effect your having.  Also, consider starting out slow like 1 tab a day and when side effects diminish-which they often will-add another pill and repeat till side effects remain then back off to what you can tolerate.  A low dose may  he better than nothing.  Hope I'm not being pushy...just some thoughts.  Tony
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: QuackAttack on October 13, 2017, 10:11:29 PM
DP,

If you are in the DC Metro and have military benefits and can go to Walter Reed in Bethesda, go see Dr. Robert Dean. Dr. Dan is the Chief of Urology and I have found him to be outstanding.
Title: Re: DMSO, DMSO based Solutions and TOPICAL Treatments
Post by: dplookin on October 14, 2017, 04:53:55 AM
QuackAttack..........Thanks, but I'm on the West Coast.  It seems like every time I go to the VA to see an Urologist, there's a different one there, and the last time I was there (recently) there was some young female urologist and I couldn't really discuss this problem with her.  It would be too uncomfortable.  Even though my problem is in the the computer there, she didn't bring it up.  I was initially there due to some past cancer issues.  I did drop some hints about the Peyronies, but she just ignored it.  I attempted to get some Cialis, but that was a No No.  She gave me a prescription for Levitra.  The prescription consisted of 2 pills only.  What a Joke.  Thank you, dplookin


TSanchez............About the Pentox, I really can't take that stuff.  It was OK until the 4th week, and it caused Severe Constipation, which happens to 71 % of the people in my age group.  I did some research on Pentox back when I was taking it.  It's not for me for sure.  Thanks, dplookin