OTHER IDEAS & SUGESTIONS – causes of Peyronie’s

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MikeSmith0

hypothyroidism is not as common in men as it is in women - so docs tend to forget men have thyroid glands too... but healing issues (delayed healing, poor healing) are associated with hypothyroidism.  cell metabolism is negatively affected.  there may be a loose correlation between the two.  Also,  hypothyroidism hurts sex drive - and this has the "cascade" we often read about here...where libido declines, erectile quality declines, nighttime erections decline, and then a minor injury during sex with a 70% erect penis can happen more easily.  so there are a few ways it could be connected.  Low T is also correlated to peyronie's in a paper by a top urologist just out last year (morgentaller) - but the problem is that T drops with age so it's hard to know what the salient variable is in his study...age or T level.  roughly half of men with Peyronies Disease have normal T levels...and most are probably healthy in the thyroid department too - but that doesn't mean these are not contributing factors in some men.  if you have low T and low thyroid, certainly fixing them couldn't hurt... whether it will reverse Peyronies Disease will be hard to predict - but would take a very long time.

hyperthyroidism doesn't seem like it would have a connection from a theoretical perspective.

Justin

So far i've tried homeopathy, chinese medicine, vitamin e, b complex, quercetin, sod pills, immune-boosting herbs, creams, massage........ obviously i need to change my regime as nothing has touched it so far. The ved is all very well but comes across as being a bit bulky. How many hours a day would one have to wear it to see any difference? As for supplements, i had thought of buying serrapeptase and nattokinase, but seeing as i don't truly know what would work it's all a shot in the dark. Plus i can't afford to buy these things at the moment.

I'm doing a massage/stretching thing once a day, no results as yet but it keeps the blood circulating at least.

Thanks for the advice, keep up the good fight.

sgtnick

Mike,

Thanks for the reply.  I had a physical done on 1-7-11 and should have the results (blood work) today 1-11-11.  Fatigue, indifference to diet/exercise, slow libido, etc have crept in.  All my symptons are related to both Low T and Hypothyroidism.  My Doc is very liberal with meds and I am concerned a little with mixing two different treatments.  I am also scheduled for implant in April.  While I was talking with the Doc his nurse practioner was taking notes and when he left the room she said I needed thyroid workup as well as T.   Women don't miss much.  When I read symptoms of Hypo. I was pleasantly surprised at how closely related the two are, both hormonal conditions.  Also. I live in a small town and something like a penile implant is hard to keep secret, a lot of people are concerned about my new bionic dick.  ;D

Old Man

Justin:

Somehow, you must be confused about VED therapy. One does not "wear it", but "uses it" in a controlled regimen of exercises as explained in the 26 week protocol listed in the VED board section of the main forum home page. Suggest you spend some time browsing through all the posts and threads dealing with VED therapy.

Old Man
Age 92. Peyronies Disease at age 24, Peyronies Disease after
stage four radical prostatectomy in 1995, Heart surgery 2004 with three bypasses/three stents.
Three more stents in 2016. Hiatal hernia surgery 2017 with 1/3 stomach reduction. Many other surgeries too.

MikeSmith0

Quote from: sgtnick on January 11, 2011, 06:37:34 AM
Mike,

Thanks for the reply.  I had a physical done on 1-7-11 and should have the results (blood work) today 1-11-11.  Fatigue, indifference to diet/exercise, slow libido, etc have crept in.  All my symptons are related to both Low T and Hypothyroidism.  My Doc is very liberal with meds and I am concerned a little with mixing two different treatments.  I am also scheduled for implant in April.  While I was talking with the Doc his nurse practioner was taking notes and when he left the room she said I needed thyroid workup as well as T.   Women don't miss much.  When I read symptoms of Hypo. I was pleasantly surprised at how closely related the two are, both hormonal conditions.  Also. I live in a small town and something like a penile implant is hard to keep secret, a lot of people are concerned about my new bionic dick.  ;D

If your labs show a low thyroid, you really have to treat it... if you do not, that is how you can get a goiter.  The brain keeps telling the thyroid to produce (via TSH = thyroid stimulating hormone) and in response, the thyroid grows additional cells.  Over years this can become a goiter - after you've gained 100 lbs and are freezing all the time thanks to low thyroid function.  You definitely need to treat it.  

Low T treatments is more controversial but there are easy ways to treat it like Clomid... vs. direct testosterone.  

Both issues are almost entirely separate as far as I know.  The two hormone pathways don't really intersect.  The only rare / weird intersection is that one rarely used thyroid treatment (Cytomel) raises SHBG (Sex hormone binding globulin) which will bind up your free testosterone...but most docs to not prescribe cytomel and it doesn't raise SHBG in everyone.  

BrooksBro

Peyronie's, Lederhosen, Dupuytren's, vitiligo, hypothyroidism and hypogonadism, are all sometimes found in the same patient, indicating to me there is pituitary (primary hormone center) involvement, and perhaps a genetic component.

More recently, I have been reading about high prolactin levels in men contributing to ED, and not only by suppressing LH production.  The prolactin level is not tested in men nearly as often as in women.

Hormones, yeah, they're everywhere, and they are so complicated, negative feedback, and so forth.

Justin

Ah, i'm getting ved confused with traction devices........... So how long do you use the ved for each day? I've had a 20 degree curve under the head of my penis for 3 and 1/2 years now, would it respond to a ved at this stage? I should add that it still hurts and has only ever progressed, albeit very slowly. Will it ever stop?!  :-\

Old Man

Justin:

The only way one can determine if the VED therapy will work for them is to try it. The best results with VED therapy have been with the three cylinder type, namely the Vitality OTC three cylinder VED or the Somacorrect VED (Requires an RX from a doctor).

Read the posts about VED therapy on the VED board shown on the home page of the forum. It explains the schedule of daily exercise session as well as other notes about VED usage.

In addition, there are many posts throughout all the threads on the VED board section of the home page menu which would be helpful for you in determining if you would want to do the VED therapy.

Old Man
Age 92. Peyronies Disease at age 24, Peyronies Disease after
stage four radical prostatectomy in 1995, Heart surgery 2004 with three bypasses/three stents.
Three more stents in 2016. Hiatal hernia surgery 2017 with 1/3 stomach reduction. Many other surgeries too.

George999

Justin,  I really agree with Old Man here.  I would cautiously give it a try carefully following Old Man's guidance.  You might even find that it brings some relief from the pain.  Careful stretching of tissues can be very therapeutic. Its what they do with people in hospitals after surgery.  - George

Justin

Ok, thanks guys, i'll start looking into it. I have to say that i remain skeptical, but given the state of my penis i'm willing to try anything! And if you say it works, i'll take your word......

Ben

Chronic pelvian pain is due to ligament or/and muscle damage. The overall condition is linked with physical trauma(s) (identified or not).
This is well known to trigger peyronie but in NO case depression is linked to this condition. Some people suffers from excessive collagen proliferation is a dysfonctionnal response of auto-immune system.


Tim468

Ben, a lack of evidence linking two things together is not the same as a proof there is no connection.

There are abundant data linking emotional states (including depression) to increased pain and suffering. I know of no good data regarding stress and emotional changes and chronic pelvic pain, but the concept that there might be a connection is reasonable.

I think that thinking that only stress or depression accounts for pelvic pain is worse than naive - it's just plain dumb and could possibly lead folks away from good therapies as you are suggesting.

Tim
52, Peyronies Disease for 30 years, upward curve and some new lesions.

sgtnick

Some of this stuff being discussed appears to me to be mumbo-jumbo; very confusing.  :'(

I discovered (for myself only) that I cannot maintain exceptionally good mental health without good physical health. [Re: cardio vascular workouts with weights and release of endorphins].  Also, I cannot maintain an exceptionally good physical state without a positive outlook.  So, obviously I can't have one without the other.

Now, what I have not discovered is how all this will help straighten a broken/bent dick :o clogged up and distorted with plaque, scar tissue or whatever the hell turned it into a pretzel.

Trying to think Peyronies Disease away appears to me like trying to control diarrhea with "The Power Of Positive Thinking"  I don't believe it will work. ;D

George999

Quote from: sgtnick on January 21, 2011, 10:49:19 AM
Some of this stuff being discussed appears to me to be mumbo-jumbo; very confusing.  :'(

I discovered (for myself only) that I cannot maintain exceptionally good mental health without good physical health. [Re: cardio vascular workouts with weights and release of endorphins].  Also, I cannot maintain an exceptionally good physical state without a positive outlook.  So, obviously I can't have one without the other.

Now, what I have not discovered is how all this will help straighten a broken/bent dick :o clogged up and distorted with plaque, scar tissue or whatever the hell turned it into a pretzel.

Trying to think Peyronies Disease away appears to me like trying to control diarrhea with "The Power Of Positive Thinking"  I don't believe it will work. ;D

I could not agree more with this assessment.  But I would suggest that good mental health can provide the CLEAR THINKING necessary to use strategies known to work in alleviating Peyronie's symptoms rather than chasing after things like Peyrotin and Neprinol.  AND, I would suggest that good physical health provides a PLATFORM for healing when it comes to Peyronie's.  - George

nycsurfer

I have never seen a posting about this but I first got Peyronies a week after I went in for a colonoscopy.  It seems such a natural that that was the cause given I had nothing like it before, yet when I mentioned to my urologist he said that was impossible.  I thought perhaps being in a totally inert state because of the anesthesia couple with them fooling around in there.

Anyone else connect a colonoscopy with the onset of this disease??  

Thanks.


BSSS


has anyone ever researched if there's a correlation between peyronie's and alzheimer's?  Both involve plaques obviously?

thanks,
BSSS

boomerang

Whilst I would like to chill out more and I am sure this would be beneficial in producing chemical changes in the metabolism I still think the depression is linked to lack of oxygen and glucose to the brain. My wife who has MS a totally differnt disease is now taking Neprinol (which incliudes serratiopeptidase) and suddenly after 38 years has no fatigue at all and does not get tired until normal bedtime.  She can now walk for more than 50 yards without collapsing like before. I am hopefull that this will clear fibroids also.   So this treatment seems to work for other diseases.  

I am all in favour of being relaxed and I am sure it could have a beneficial effect but also I think that some sort of treatment to attack the actual cause of the disease is needed.  My personal thoughts are that the cause is infection of the cardiovascular system.  There may be many infective pathogens involved but being relaxed has certainly been shown to help the immune system fight off infections.

I thinnk the treatment needs to be multiple.  Relax more, take the pills.  In the meantime I wish there would be more research into what bugs are actually causing this and many other diseases.  Stretching scar tissue is also known to help.


BrooksBro

I am trying to adjust how I think about my treatments and medicines, in the same way I am trying with my running.  Despite what I do, that therapy (or training) may not change the outcome.  I may want a sub-4 hour marathon.  Even though my training program says I "can" achieve that, on race day, it may not happen.  If that is my goal, and should I not achieve it, have I 'failed?'  I think not!  But, if that was my dominant mind thought, it is hard to not conclude that I did fail.  

It can be depressing to focus exclusively on the results, especially when they take a long time, or may never happen, or are not what you expect.  My adjustment is to focus more on the daily process, and less on the outcome.  Of course, with this condition, I want the desired outcome, to be straight again!  

As I said, I am trying to adjust my thinking to focus more on doing the daily physical therapy (traction followed by VED), taking my medicines, and enjoying sex as often as possible.  That is the best I can do, because those are what are totally under my control.  Achieving a straight penis may or may not happen as a result of my current treatments.  

I have not fully made this adjustment in thinking, for either running Peyronie's, but I am working on it.


philpot

Had a colonoscopy 2 months ago now have Peyronies system but think it may be blood pressure pills?

LWillisjr

I don't see how there would be a connection between the two.
Developed peyronies 2007 - 70 degree dorsal curve
Traction/MEDs/Injections/Surgery 2008 16 years Peyronies free now
My History

George999

If the underlying cause is metabolic, all kinds of things could trigger Peyronie's.  From colonoscopy to blood pressure pills.  In fact, even the anesthesia used during a colonoscopy could theoretically trigger Peyronie's.  You are dealing with a complex metabolic environment, depending on a balance of healing processes.  You upset that balance that is already under pressure and all sorts of things can happen, including Peyronie's.  People talk about "trauma".  In actuality our bodies sustain tiny injuries day in and day out and there is a continual healing process going on.  Anything that interrupts that results in disease, the kind of disease that doctors don't understand since its origins are not clear cut like a bacterial infection or an obvious imbalance of body chemistry.  Instead this is a subtle, sub-clinical dysfunction in which inflammation becomes unchecked and the ability to achieve healing fades.  - George

sangs

I had a colon exam done a few years ago and it seemed my problem started shortly there after .Does anyone think its possible this caued my problem or maybe just a coincidence .I dont seem to have the plague or hardness most have so Im not even sure its really peyronies or some other problem . My urologist just said take vitamin E.He never said Peyronies.

All I know is what was once straight is now curved.

Luciano

Although you never know, I doubt it came from the exam.
Could just be a coincidence.
I would suggest though you go and see an andrologist, or an urologist who is specialised in this kind of problems, who is up to date with the newest studies.
Just giving vitamin E sounds he doesn't know what you have.

Luc

nycsurfer

Luciano - the EXACT same thing happened to me.  

I had a colonoscopy and a week or two later later developed Peyronies.  I even posted on here and everyone said there was no cause or effect.  However, since then I have found a few others on line whom this was true for them also.  I am a VERY athletic person and know by body well and it is TOO MUCH of a coincidence for me.  ]

I do not rule out either that perhaps it was the anesthesia (I was knocked out for it - were you?) but wish I could get a professional to investigate becasue I have found a number of people for whom this was true also.  Thx and good luck  

George999

Guys, there are tens of thousands of guys out there having colonoscopies and they are not getting Peyronie's as a result.  There are lots of guys with Peyronie's who have never had a colonoscopy.  The reality is that Peyronie's tends to occur due to minor trauma.  Minor trauma can occur as a result of every kind of medical procedure under the sun as well as a plethora of drugs or simply simple accidents.  The trauma is NOT the cause, it is merely the TRIGGER.  You all had something else promoting Peyronie's and then you had the colonoscopy and it tipped the balance and suddenly you have Peyronie's.  You can easily be in an excellent state of health outwardly but be seriously ill inwardly.  That is doctors do all sorts of diagnostic testing like blood testing and imaging.  There are still serious health problems that are undetectable by any of these methods.  The metabolic conditions that cause Peyronie's are in this category.  They are undetectable metabolic imbalances that set you up for Peyronie's with any minor occurrence of trauma.  - George

crashbandit

I remember awhile back, about someone from this forum saying that they may have got Peyronies Disease during surgery while knocked out. They were placed on their stomach and an erection occured, but due to the anesthetic, was unable to move. Maybe this happened to you? The difference between this and someone just sleeping one night. Is that the person just sleeping, can feel pain and be able to shift their body to prevent injury, even while sleeping.
Cheers

fubar

All this is speculation as there are is not a true associated symptoms .Maybe we should make a register of symptoms and problems as a group. I have may things people think are common denominators in this disease.frozen shoulder, metopropol,  simvistatins, diabetes,  gout, infections and others.

Might be a good idea to collect our ailments and symptoms ,storage all that we ail from.Make a bank of all this crap we have in common if for just private discussion.At least Peyronie's would not always be of topic.Maybe another vehicle to help find a cause or the common denominater.

Such as cold feet I have so many symptoms I forgot this one when I first spoke to Crash and that was a prevalent symptom when Peyronie's came and knocked at my door.

We have many things in common but we are human and should.

Fubar

sangs

I forgot to mention I am on Metroprolol.I didnt know this was also considered a cause.

George999

Metoprolol is a beta-blocker.  Beta-blockers have a notorious association with Peyronie's.  So that is just one more factor of many that played into your demise.  Peyronie's is a result of low level metabolic dysfunction caused by multiple factors that come together to create a perfect storm wherein the most minor of additional injuries (like something related to the colonoscopy) would tip the balance and the result would be Peyronie's.  In any other situation you would never have even known that you had been injured, since it would likely heal painlessly within hours.  - George

fubar

Geoarge

I took one metopropol yesterday the first time in a year.My heart was beating out of my chest.30 minutes out. The trip began was like old times.First the runs second puking. On and on for a couple hours.

Then eyes rolling into the back of my head, like I was fighting to be awake.Nausea through out the day heavy. Feat. It goes on but I will never take this junk again.

FUBAR

fubar

Really it was hell, can not believe I chose to take it again.I was scared to death but me I go on no matter how I feel.It was as I described I did not mention the pain it put me through.I can not believe my doctors wont listen to me. It has been a year with Peyronie's and bph 186 over 120.

Fubar  

George999

I am currently taking a bunch of stuff trying to deal with my hypertension, and having some measure of success.  I will PM you with some things I am learning.  - George

fubar

George

I would be greatful for anything to aid me. I'm sick and tired of getting nowhere and is a major stress.

Fubar

crashbandit

Sorry to hear about the high blood pressure fubar, that sounds very crappy , hope you are feeling better soon.

George, could you send me that info as well by chance please? Thanks in advance.

I've been having big problems with flushing in the face and mild chest pains since starting cialis. Is it possible my regime of Cialis and pentox could be causing this. I noticed bad flushing while drinking after starting pentox and now that I've added the cialis, the flushing is bad all the time, expecially when stressed. I thinking about dropping my cialis dose to 2.5mg every other day.

Anyone experiencing bad flushing with pentox and cialis?
Cheers

George999

Guys, I posted some information on  hypertension issues in the off topic area, perhaps we can discuss it there.  That will save me from PMing multiple people here.  - George

dioporcolorisolvo

I made a colon exam in October and i had peyronie in December, but in November i had also a sexual trauma. And my father has Duputrien.  

BENBEN


Last month I have been diagnosed with Peryronie's Disease.
After doing a lot of reading, and visiting an urologist, I still can't figure out why it happened to me.

There is no history of penile trauma or rough sex, however, I am practicing Tantric sex routinely for over 10 years.
The Tantric practice involves having continuous erection for a couple of hours, with varying degrees of rigidity. The erections are very satisfying and occur naturally without any aids (chemical or mechanical) and with no pain.

Questions:
*  Do you know of tantric practitioners who developed Peyronies Disease?
*  Can these prolonged erections be the cause of Peyronies Disease?
*  If Tantric sex is continued, would it worsen the disease?
*  Should I stop practicing Tantric sex?

Thanks.



Tim468

The bottom line is that men of all sorts get Peyronie's Disease. Some sort of "trauma" is hypothesized to have occurred, but many of us wrack our brains trying to remember some sort of injury and cannot really find anything (or we invent something and obsess about it).

Some behaviors seem to be more risky than others, like trying to elongate the penis with jelqing, or mis-using a VED in a prolonged way at too high a pressure. But for most of us, there is not an identifiable event/cause.

Tim
52, Peyronies Disease for 30 years, upward curve and some new lesions.

BENBEN



Right, Tim

Perhaps the question should be asked in broader terms.
Does anyone know about cases of Peyronies Disease apparently caused by prolonged erections? (e.g., by Viagra).
I'm not referring to Priapism or over-pressurized VED, since they are already known to sometimes injure the penis and cause Peyronies Disease.


Tim468

To my knowledge prolonged natural erections are not associated with Peyronie's. Some have reported developing it after prolonged bouts of fairly hard intercourse, but that is different than what Tantric involves (usually at least).

Tim
52, Peyronies Disease for 30 years, upward curve and some new lesions.

BENBEN


skunkworks

Technically a 4hr+ erection could cause fibrosis.
This is an emotionally destructive condition, we all have it, let's be nice to each other.

Review of current treatment options by Levine and Sherer]

George999

Guys,  I'll say it once again.  Peyronie's does NOT occur because of something you DID.  Peyronie's occurs due to an underlying metabolic problem.  Normal guys have all sorts of penile injuries and never get Peyronie's.  Extended erections cause corporal fibrosis, NOT Peyronie's.  But normal guys seldom even get corporal fibrosis unless they are misusing PDE5 drugs.  If you look at all the purported causes of Peyronie's on this forum, they are all over the map, from beta blockers to antibiotics, from colonoscopies to too much masturbation.  But these are just rabbit trails.  Until guys start to deal with the underlying metabolic issues they are just tilting at windmills.  Treatments are fine AND necessary.  Pentox, Ubiquinol and VED are all clearly effective.  But the fire that fuels this stuff is metabolic, and at some point unless we stop pouring gas on that fire we are not going to achieve much.  - George

BENBEN

Quote from: George999 on May 23, 2011, 03:19:38 PM
Guys,  I'll say it once again.  Peyronie's does NOT occur because of something you DID.  Peyronie's occurs due to an underlying metabolic problem.  Normal guys have all sorts of penile injuries and never get Peyronie's.  Extended erections cause corporal fibrosis, NOT Peyronie's.  But normal guys seldom even get corporal fibrosis unless they are misusing PDE5 drugs.  If you look at all the purported causes of Peyronie's on this forum, they are all over the map, from beta blockers to antibiotics, from colonoscopies to too much masturbation.  But these are just rabbit trails.  Until guys start to deal with the underlying metabolic issues they are just tilting at windmills.  Treatments are fine AND necessary.  Pentox, Ubiquinol and VED are all clearly effective.  But the fire that fuels this stuff is metabolic, and at some point unless we stop pouring gas on that fire we are not going to achieve much.  - George




Is this statement supported by medical findings?
Or perhaps it is just your general impression based on anecdotal observations?

On the other hand, it seems to me that the claim about Peyronies Disease caused by penile trauma is a common knowledge among urologists since it is supported by repeated findings.

Of course there is another possibility: An underlying metabolic problem makes some guys (us) more susceptible to penile trauma.



BENBEN

Quote from: skunkworks on May 23, 2011, 11:06:20 AM
Technically a 4hr+ erection could cause fibrosis.


You are correct if maximal rigidity is maintained continuously without blood circulating in and out of the penis. This is a pathological condition, not a natural enjoyable erection.

George999

Quote from: BENBEN on May 23, 2011, 04:15:47 PM
Is this statement supported by medical findings?
Or perhaps it is just your general impression based on anecdotal observations?

On the other hand, it seems to me that the claim about Peyronies Disease caused by penile trauma is a common knowledge among urologists since it is supported by repeated findings.

Of course there is another possibility: An underlying metabolic problem makes some guys (us) more susceptible to penile trauma.

Its a medical fact that many men experience considerable trauma to their penises and never develop peyronie's.  It is also a medical fact that diabetics are much more likely to contract Peyronie's than non-diabetics and that implicates a metabolic factor.  Common logic tells one that one doesn't suddenly go from 0% risk of Peyronie's to 50% risk with a mere 5mg/dL of serum glucose.  Is it a stretch to assume that some people are probably genetically more affected by elevated (but not yet diabetic) levels of blood sugar than others?  If lowering blood sugar can *reverse* kidney failure which is also considered an incurable disease, what might it do for Peyronie's.  Blood sugar is *highly* inflammatory and does weird things to the blood causing damage to all the tissues it touches.  Elevated blood sugar is especially toxic to the mitochondria that power our cells.  But the real damage comes with a trigger.  Something that upsets the equilibrium and requires the healing process to begin.  At that point cells are stressed and they can't handle both injury AND elevated levels of blood sugar 24/7 AND most likely a degree of genetic damage as well.  It becomes a perfect storm.  Its only a matter of which organ fails first ... or second, or third, etc.  - George

Referrence -> http://www.the-diabetes-detectives.com/2011/05/scientists-announce-diet-that-reverses.html

BENBEN



Trying to figure out the logic of Peyronie's symptomatic treatments, it seems that there are two main methods:

*  Flushing the damaged tissue with plenty of fresh blood, in order to revitalize it and regain elasticity – e.g., using heat, VED, specific drugs/supplements, etc.
* Stretching the scar tissue in order to minimize penile bents and the accompanying pain – e.g., using traction, VED, etc.

If this rational is correct, then wouldn't it be advised to encourage increasing the number and length of natural erections as much as possible (self or intercourse)?

It goes without saying that all types of treatments should be exercised with extreme care to avoid exaggerations/tissue damage.

Guys, does it make sense?



George999

Flushing with fresh blood alone will do little good.  What is required are very specific agents that address the inflammatory syndrome behind the disease.  That is why there are so few substances that actually work.  Pentoxifylline specifically blocks the key inflammatory agent, TGF-beta1.  That is what makes it effective.  CoQ10 protects cellular mitochondria from inflammatory damage, that is what makes it effective.  ALC is effective via its antioxidant properties.  You can go down the list.  Each of the known effective substances is effective via a known pathway.  Viagra and L-Arginine flood the penis with blood, but both of them have been abandoned by Peyronie's specialists because they have been found not to be effective in the long term.  There is a well defined science behind the treatment of this disease and it is not about blood supply.  - George

Tim468

There is plenty of blood flow to a flaccid penis - an erection is not designed to "increase blood flow". Instead, erections promote the pooling of blood in the cavernosa.

Again, a normal erection that lasts a long time (ie four hours) is different than priapism.

Tim
52, Peyronies Disease for 30 years, upward curve and some new lesions.

BENBEN

Quote from: George999 on May 25, 2011, 09:57:00 AM

Each of the known effective substances is effective via a known pathway.  

There is a well defined science behind the treatment of this disease




What are the medical mechanisms behind traction, VED, heat, massage?  Why are they effective in alleviating some symptoms?
Isn't it a kind of simulation of processes occurring during natural controlled erection (intermittent, not violent)?