DMSO and CO.

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kovasis

Hi to all in this Section of the Board...
You may read my indrodution or just may kindly read what i have to report now.

In between i saw antoher Specialist in Hamburg (in the end of mai this Year - almost three Month ago ) - Finally i just spend the Money (paid completlty on my own) to see him , of course because I'm kind of despaired...
I was examined for about three hours and besides the already known Plaque on my base, it turned out, that my ED is related due to many blood flows out , to quick.
He examined via Doppler Ultrasound (I was given an Injektion prior to that examination).
The Erection was week (E3).
He explained that this is not due to a venous lekage , but due to , too  many collagen and to fiew flat muscle in my penis, which of course is reverseable by using :
5 mg Cialis and 50 mg Sildenavil prior to sleep every Day and a vacuum device (which i already use).

All other Aspects , besides the Plaque where ok, like no dramatic curve and so far as i can tell only a 1cm or 1,5 cm loss in lenght since peyronnies occures.

he pescribed me pentox (3x400) as well , but after about two Month I had to go down to 2x400 and sometimes 2x400 plus 200 becuase of GI Problems triggered by pentox.

So far I see no really success with this Treatment , it seemed that the Plaque on the Base is still growing to the left side of my shaft, in between it almost reached the complete left end...

I wonder if it maybe someday will progress completly around the whole BASE of my Penis... is this even possible?

Only positive thing is that the flaccid pain is almost completlty gone since i Take pentox. Sometimes i got a sore feeling after intercourse, but thats it.

Since one Week the nocturnal erection are week and it is hard to get an erection (even with 50 mg Sildenavil) an hour prior  to intercourse.

Since then 50 mg or 75 mg worked well for me.
I took Sildenafil for about three Month now daily...
I wonder if inbetween i tolrate the dosage? - is this Possible?
I asked the professor at Hamburg a couple of weeks ago the same question and he explained me that one cant get a tolrance against PDH5 - Hemmer, once they worked they should always work...

I'm not so sure.
I have to admit, that my Libido is not the best currently , I'm still smoking (up to  16 Cigarettes daily) and are stressed at the job, privacy and of cource still by that rotten desaese...

maybe my weaker morning woods and the ED in General are more related to that, than another reason - i dont know.

I Read about DMSO on this Forum and it soinds completly logical to me to give it a shot.
So I ordered 50% DMSO and use it since a couple of Days by rub it directly to the skin , where the Plaque is palbable.

I will keep you informed if this Treatment will show any kind of success...

The Palque is like 3 cm in lenghts (just a guess) and i think at least 1cm in height (also just a guess) . I cant really  measure it and no Dr. did it in the Past.
I only fell it and two guess it's size I put it between two finger and slighly press against both ends - yes its also hard to explain :-).

15 Month in now... if it is true what is said about the acute and the stable Phase - it should be over in about three Month...

Currently I'm taking:
5 mg Cialis Daily
50 to 75 Sildenafil daily
1500 LArginin / 500 mg LCarnitin daily
120 mg Omega 3 Fishoil daily
120 mg Coenzym Q10 daily
2 to 2,5 x 400 mg Pentox
DMSO GEL (50%) daily (directly rubbed to the Skin)
10 to 15 Minute VED Sessions 4 to 5 Days a week

I Consider to take 10 mg Cialis per Day - does someone have experience with that dosage?
Is there a possibillity to reduce the side Effects of Pentoxifillin?

Does anyone here also have expieriences with using the DMSO Gel?




Age 51
First onset of Pyronnies  June 2016
Indurations under the glans and at the base.
4 Years Stable
Daily use of 5 mg Cialis and 300 mg Pentox

lessor

Quote from: kovasis on September 07, 2017, 04:36:09 AM

He examined via Doppler Ultrasound (I was given an Injektion prior to that examination).
The Erection was week (E3).
1-He explained that this is not due to a venous lekage , but due to , too  many collagen and to fiew flat muscle in my penis, which of course is reverseable by using :
5 mg Cialis and 50 mg Sildenavil prior to sleep every Day and a vacuum device (which i already use).


2-Since then 50 mg or 75 mg worked well for me.
I took Sildenafil for about three Month now daily...
I wonder if inbetween i tolrate the dosage? - is this Possible?


3-maybe my weaker morning woods and the ED in General are more related to that, than another reason - i dont know.

1- I doubt very much that what your doctor said is true, but I think it's a lie to calm you down. I dont believe it is reversible, i dont know people who reverseable it but well...
2- Yes it is possible many people experiment it, at the beggining it work better after is worse. Many people say it many people experiment it me too
3- I doubt it, psychological ED is the typical what a doctor will tell you in oder to calm down, also morning and nocturnal woods should be presents if it is psychological. Also if with injection you didnt get an erection..
What did he inject in you? Caverject bimix maybe tri?

kovasis

@lessor
Thanks for your Respond, it sounds very pessimistic to me...

I Think as every one is different (They all tell again and again) its hard to tell if it is a lie what he tells me.
His Explanation of the ED Reason he'd explained to me does make sence and you can read about it (at least many german Sites) where it is described in Detail also.
So assuming that he lie's to me does not make many sence, since this person is not one of that common so called urologists and Andrologists who mainly whant to get rid of you and partially even dont know almost nothing about this condition...

I visited 6 of them and thervore i know what I'm talking about when it comes to finding a real specialist :-).

I had another Session with another specialist a couple of Month prior to that Appointment in Hamburg, where they performed a caversonography which shows no lekage and no damage to the Corpus Cavernosum at all. The Plaque sit's outside and does not disturb the regular blood flow.
I dont know what kind of Injektion it was (to know i have to have a look at the Report) , but i Know it was a caverjekt with 3/4 more of the Stuff  than they gave me in Hamburg.
The Erection lastet for one Hour (E4) and was straight.

Concerning the psychological Effekt on ED , i would also not say that this is out of the Question , or an argument They use to calm you down.
There are Several Reports out there where you can read about a connection.
my own Expierience is that in times of psychological stress and other stressed related situations , it seemed that it indeed have a Impact to my Erections.

So my case is that Morning Erections are weaker (since one Week) , but I'm able to get an Erection for Intercourse (of course with 50 mg Sildenafil).

Sometimes in the past weeks it was even possible without taking the Sildenafil, maybe then the 5 mg Cialis did their Job and the fact that in this Situations I was calm , was on Holiday and almost had no stress at all.

Thats why I believe that there is a connection between psychological stress and ED.

That beeing said,
What is your Experience in detail? How long did you take the PDH5 Stuff and in waht dosage?


Age 51
First onset of Pyronnies  June 2016
Indurations under the glans and at the base.
4 Years Stable
Daily use of 5 mg Cialis and 300 mg Pentox

lessor

I wasnt referring that you have venous leak, I meant that i cant see as collagen would be reverseable, IMHO it is very difficult that it can change, maybe if the problem with collagen is recent it could be possible in other case i think its not possible, in my opinion.

I said he probably is calm down you because behind of pills and injection only is the implant and as you said your first injection didnt work... but you said your second injection worked so now it changes. Maybe not but many urologist do this, especially if you are young

And about psychological ED, almost never psychological ED is the cause of ED,  if you can get an erection and maintain it without problem while you are watching porn, well so it is very probably your ED is psychological  but in other case is more likely it isnt psychological. They always use the argument of psychological  ED for young men, it is always so, and the sense of this is the same that the part above (implants)

Anyway if you can maintain your erection without problems with cialis or viagra it is ok, you wont have to worry, at least not in many years

And about PDE5 I began taking cialis 10 mg, the first times it work something, i mean with the girl in top i couldnt maintain the erection impossible, in other possition it was easier, but this which wasnt perfect gave worse and I took 20 mg cialis and the same at the beggining better but later it gave worse and now it doesnt work. I have read this in others men but with more time than in my case.

kovasis

@lessor,
OK I understand your point now.
Concerning the Collagen/Flat Muscle Mix :
They say (Reports and Internet Search and the Professor at Hamburg) that there has to be a Mix abaout > 50% Flat/smooth muscles Muscle to < 50 % Collagen.
so an amount of 50 to 55% smooth muscles is optimal.
What they mean is , by increasing the smooth muscle you can obtain better Erection quality again...

https://www.maennergesundheit.info/erektionsstoerungen/praevention/sauerstoffversorgung.html

PRIOR to my appointment in Hamburg I was given Caverject 20 ug prostaglandin which worked fine to induce an Erection .
At Hamburg a couple of month ago they gave me Caverject 7,5 pg Prostaglandin which obvisously was not enough to induce a good erection.

Concerning the adaption of Viagra and Co. there is no Scientific Report that Confirms that , it seemed that the main Reason for this issue (that it does not work anymore , or not as expected after Mionth or Years of use) is , that the underlaying ED Problem is getting worse or again a Psychological problem.

Yes , i can get and maintain an Erection by using Porn , or prior to intercourse , but it seemed that is more diffcult at least since  one Week now, thats why i assume that it could be related due to psychological  reasons or the adaption of Cialis and Sildenafil.
I also have a suspicion concerning the VED , that it may cause my weak Nocturnal Erections...
I will Pause the Training at least for two weeks and will Report then.

The Professor said that he see's no rationale for this, but i will see, if this is the reason for my issue (currently).

I had the same problem with the Girl on Top position as you described (as far as i know i already mentioned this in one of my recent Posts). After a couple of weeks i changed the relationship to another Girl... and guess what? The Postion works again...

Concerning an Implant, i have raised a topic on this Board, I'm still playing with that Idea to have one instead of going through all this crap...


Age 51
First onset of Pyronnies  June 2016
Indurations under the glans and at the base.
4 Years Stable
Daily use of 5 mg Cialis and 300 mg Pentox

lessor

With your age if you are getting problems with erections with cialis or viagra implant seems a good good option (you are 46 true?) If I were in your age and pills dont work or every time it is getting worse I would go for the implant sure. Sure you know FT
If i were older, if i were in my 40s or 30s I would go for it


Regarding to VED I suspicious if you pass with the pressure it could be dangerous.. just my opinion, i know it works well for many people but I dont feel confortable doing VED.I read about injuries with it

About pills what did you say its possible I read in some place pills and injections can worse ED with the time.. not sure why

kovasis

Yes I'm 47 - How old are you?
Well I hope its not getting more worse since Implants has its own concernes to be aware of as you may know and yes i read a lot at FT.

I think ED only get worse if the underlying condition is getting worser regardless if you took the pills or not.
The Only connection between getting worser due to pills and Injections is the correlation with peyronnies in the acute Phase because injection may cause more injuries and pills (when overused ) can make you less aware of what you are doing during performing intercourse - just my opinion.

In between i dont see the very purpose of using a VED since you have nocturnal Erections and many times of intercourse or masturbation . I think VED is used to be kind of substitution for either nocturnal or  self induced Erections because it is used to fill your penis with oxygen rich blood , which happend to be sufficient enough when reaching in the other ways.

I know that there is mabe the one or the other benefit as well using it in adition , but inbetween i consider it kind of dangerous .
I will not use it that often anymore , just to see (as i mentionioned earlier ) if the nocturnal Erection will recover in quality...

Age 51
First onset of Pyronnies  June 2016
Indurations under the glans and at the base.
4 Years Stable
Daily use of 5 mg Cialis and 300 mg Pentox

kovasis

OK , so i leave VED Sessions since last week.
NTE's are straight again...
I dont know if there is really a connection , or if it is an coinszidence with some other components , but at least for me (in my case) it looks like if there is a connection between VED and NTE's, even if there is no rationale for this...

Age 51
First onset of Pyronnies  June 2016
Indurations under the glans and at the base.
4 Years Stable
Daily use of 5 mg Cialis and 300 mg Pentox

kovasis

I also stopped using the DMSO Gel , because i had a burning and inflammatory feeling since i used it , about 4 to five days ....
maybe continue using it in a couple of days , just to see if there is a connection to that burning feeling , which is still there .
weired thing is , that it does not burn, where i applied the Gel , but directly under the Glance (left side)...
maybe triggered a new round of PDS , i dont know
Age 51
First onset of Pyronnies  June 2016
Indurations under the glans and at the base.
4 Years Stable
Daily use of 5 mg Cialis and 300 mg Pentox