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Author Topic: New Study Using Anti-Oxidants  (Read 1653 times)

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Crooked_Stick

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New Study Using Anti-Oxidants
« on: August 23, 2017, 12:58:25 PM »

This is a very interesting study using combinations of:Silymarin+ Ginkgo+ vitamin E+ propolis+ bilberry+ topical diclofenac + pentoxifylline injections. They had 5 groups using one or more of the above. The results were very significant!

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5530853/

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skunkworks

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Re: New Study Using Anti-Oxidants
« Reply #1 on: August 23, 2017, 11:53:50 PM »

That is a big result and the actual treatment would not be hard to follow, except for the pentox injections.

Diclofenac gel/spray is just Voltaren.

Reascot

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Re: New Study Using Anti-Oxidants
« Reply #2 on: August 24, 2017, 03:40:11 AM »

I've very interested in this. I'm tempted to rush out and buy as many of the supplements used, but I'm wary. When I realized I was losing my hair I tried supplements and creams galore. Saw palmetto and propecia may have contributed to my peyronies. It certainly decreased my night time erections, and we all know we need healthy blood flow in the penis to prevent peryonies.

Anyway, I'm interested in hearing from anyone on this board who has tried silymarin, ginko biloba, propolis, bilberry, and/or any combination of them.
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basebend

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Re: New Study Using Anti-Oxidants
« Reply #3 on: August 24, 2017, 09:25:21 PM »

Nice study. Anyone here have experience using topical diclofenac / Voltaren?
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Arabia

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Re: New Study Using Anti-Oxidants
« Reply #4 on: August 25, 2017, 12:52:06 AM »

Yes I tried it during the active phase for pain control and it seemed to reduce the pain by about 50 percent.  I used the strong formulation which is 2.3 percent.
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Tsanchez12369

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Re: New Study Using Anti-Oxidants
« Reply #5 on: August 25, 2017, 09:30:43 PM »

I called the pharmacist who indicated there is both a 1% and 3% Diclofec gel.  I'm trying the 3%, will increase by 25% to match the 4% gel in the study and report back with any progress.  I have also ordered the antioxidants used in the study.
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skunkworks

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Re: New Study Using Anti-Oxidants
« Reply #6 on: August 26, 2017, 07:33:47 PM »

Good luck mate!

james1947

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Re: New Study Using Anti-Oxidants
« Reply #7 on: September 23, 2017, 06:44:31 PM »

Some improvement in one moth Tsanchez?

James
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Tsanchez12369

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Re: New Study Using Anti-Oxidants
« Reply #8 on: September 24, 2017, 12:34:28 AM »

No, maybe worsening...I'm waiting to see Dr Lue on 10/20/17 and hoping to start xiaflex with the supplements.
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james1947

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Re: New Study Using Anti-Oxidants
« Reply #9 on: September 25, 2017, 08:24:57 AM »

Thanks for the update Tsanchez

I am not surprised it didn't help.
From reading all the posts on the forum for many years, very rarely I read about some topical treatment that helped with Peyronies

James
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Tsanchez12369

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Re: New Study Using Anti-Oxidants
« Reply #10 on: October 10, 2017, 09:48:03 PM »

Has anyone heard of the PTX100 injections?  Is thus pentox  and is it injected into the plaque?
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pey ron

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Re: New Study Using Anti-Oxidants
« Reply #11 on: October 11, 2017, 12:02:07 AM »

would you apply the voltaren/diclofenac on the shaft or on the glans where it gets absorbed more readily?
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Tsanchez12369

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Re: New Study Using Anti-Oxidants
« Reply #12 on: October 11, 2017, 03:42:05 PM »

I've been applying on the shaft, especially at plaque
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pey ron

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Re: New Study Using Anti-Oxidants
« Reply #13 on: October 11, 2017, 09:57:17 PM »

how would it ever penetrate to the plaque? the skin moves, it's like a glove on top. At least for an uncut penis like mine... I'm confused, maybe circumcised penises have a better chance of success from topical treatments?
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Tsanchez12369

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Re: New Study Using Anti-Oxidants
« Reply #14 on: October 11, 2017, 10:16:06 PM »

I'm not sure, but the study had better results w the cream than w/o
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Paolo

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Re: New Study Using Anti-Oxidants
« Reply #15 on: October 12, 2017, 02:41:16 AM »

Topical treatments IMO don't go deep enough, as pey ron has said the skin is like a glove, I am uncut also  :-\
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Tsanchez12369

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Re: New Study Using Anti-Oxidants
« Reply #16 on: October 12, 2017, 01:51:49 PM »

I believe it relates to the molecular weight of the topical.
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Realvinni2000

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Re: New Study Using Anti-Oxidants
« Reply #17 on: November 08, 2017, 06:14:45 PM »

Has anyone heard of the PTX100 injections?  Is thus pentox  and is it injected into the plaque?
I have those, I follow the antioxidant therapy too.
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Tsanchez12369

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Re: New Study Using Anti-Oxidants
« Reply #18 on: November 08, 2017, 07:51:46 PM »

I’m following the study but am substituting Xiaflex injections.
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pizzaman

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Re: New Study Using Anti-Oxidants
« Reply #19 on: December 18, 2017, 11:51:52 AM »

I'm not sure, but the study had better results w the cream than w/o

We don't know that the cream had any effect in the study, since they added several oral supplements with it. They added propolis, for instance, which also has some positive peyronie's research on the books. Personally, I don't think topical NSAIDs will help at all.
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Tsanchez12369

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Re: New Study Using Anti-Oxidants
« Reply #20 on: December 18, 2017, 12:07:19 PM »

True, but both inexpensive.  I’m following the protocol but substituting Xiaflex.  The article has a rationale for the diclofenac other than just pain relief. 
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pey ron

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Re: New Study Using Anti-Oxidants
« Reply #21 on: December 22, 2017, 02:59:43 AM »

Tsanchez12369: what's the purported rationale for dicloflenac?
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Tsanchez12369

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Re: New Study Using Anti-Oxidants
« Reply #22 on: December 22, 2017, 09:48:50 AM »

”diclofenac has anti-inflammatory, analgesic, and antioxidant activity, but its antifibrotic activity has also been ascertained, as it has been shown to inhibit fibroblast proliferation.81–84“
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pey ron

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Re: New Study Using Anti-Oxidants
« Reply #23 on: December 22, 2017, 09:57:29 PM »

How about taking it systemically as well, then?
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Tsanchez12369

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Re: New Study Using Anti-Oxidants
« Reply #24 on: December 22, 2017, 10:11:45 PM »

It’s a gel and mostly local to where applied.  Can penetrate to deep tissues.
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Paolo

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Re: New Study Using Anti-Oxidants
« Reply #25 on: December 23, 2017, 03:37:08 AM »

Diclofenac is an NSAID, as with all nonsteroidal anti-inflammatory drugs they should not be taken 'long term', mostly a heart risk. Having said that please update if any member gets an improvement with it  :-\

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