It was not until some 180 years later that scientists again began to delve into the mystery of regeneration. In 1945, the biologist Meryl Rose (a retired professor of anatomy at Tulane University College of Medicine who is currently affiliated with Woods Hole Marine Biological Laboratories) amputated the forelegs of some frogs below the elbows. Thinking he could perhaps promote growth by preventing the injuries from scarring over, he bathed the stumps of the frogs' limbs in a strong salt solution.
The result was startling. About half of each amputated limb regenerated, developing new bone and muscle and in some case even showing the beginnings of digital growth. Thus Rose became the first to prove that an animal which cannot regenerate naturally can be made to do so artificially.
The next year, a Russian named Vladimirovic Polezhaev amputated frogs' legs in a similar fashion and then irritated the stumps by repeatedly jabbing them with needles. The result? Astonishingly, he regenerated about the same amount of growth that Rose had with the salt solution. It was possible that the salt not only had prevented scarring but, like the needle punctures, had actually exacerbated the injuries and thereby stimulated growth. Now there was another clue: Regeneration may somhow be connected to the severity of injury.https://www.washingtonpost.com/archive/opinions/1978/08/06/growing-new-limbs/7dd8603d-6e64-4727-8d1b-47dfa8162478/?utm_term=.6f0efd97586e
I didn't read the whole article yet but lets get some salt and needles!!!