A New Theory on Cause and Treatment of Peyronie's Disease

[fbristow]

Joshua,

I will share the info., but I don't know if we're on the right track or not, be it Dupuytren's, Peyronies, plantar fibromatosis, or anything else for that matter. But I hope and pray that we are close. Thing is, I am ABSOLUTELY convinced that the answer to this and most other diseases is "out there" somewhere. We just have to find it (and then-the hard part-convincing doctors to try something that they've never heard of before). I do know know that they are looking at all kinds of vitamin D analogues (especially ones that are anti-proliferative), but don't have the problems with hypercalcemia.

Frank

This is just a start, believe me, but Kevin is doing what very few people, researchers, or particularly physician's ever do. He is putting pieces of this puzzle together. I will be writing to Kevin directly, but let me tell everybody now- the answer to many, if not all "collagen-build-up" (my term) disorders MAY be in the "ACTIVE" form of vitamin D-calcitriol. Your kidneys and liver make this from oral or sunshine-derived vitamin D. There are papers out there now showing that giving this "active" form of vitamin D to patients (careful-it can be very toxic) can stop and reverse collagen fibrotic diseases. That's what I'll say for now, but I would have not even looked at this if it weren't for Kevin. God bless you.

Send me an email, and I will send them to you. Some are abstracts, but I have one in particular where the patient was essentially cured of a desmoid (that's what I have, along with Dupuytren's), with calcitriol. I COULD be wrong, but I just wonder if all of these collagen-related fibrotic diseases to have enough biochemistry in common for this drug to work for many.

I'll put the abstract links here, but I've worked in healthcare for 23 years, and it seems lately that there's a ton of research on vitamin D, both the "inactive" and "active" forms, mostly for cancer (breast, prostate, lung, etc.). By the way, two of these papers are free for download. And it does not mean that someone has to be "deficient" in vitamin D in order for calcitriol to work. It actually seems to have a collagen-degradation activity.

Links:

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15371466&query_hl=1

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=15607567&query_hl=3

http://www.ncbi.nlm.nih.gov/entrez/query.fcgi?cmd=Retrieve&db=pubmed&dopt=Abstract&list_uids=10926872&query_hl=7

Hope this helps.

Frank

[Old Forum]

Hawk, Administrator        Posted: Wed Aug 03, 2005     2:25 am     
 
Ok here is an interesting link. Interesting because it makes more sense than I first assumed it would. Interesting because this theory was made by a person with no medical background. Interesting because of the commitment and effort this man dedicated to this effort. Interesting because I know of other doctors making a sugar, insulin / collagen connection.

I have emailed with Kevin and find this theory intriguing.

Check out

www.dupuytrens-a-new-theory.com

The following is the a discussion on the theory of dupytren's, Peyronies. and other fibrotic disorders that is a result of Kevin's research found.

This is clearly an unconventional theory.  While sounding very logical to lay persons, it has far to go before being tried, tested, and accepted by the medical community.  At the very least it is interesting, at the most it could be a set of clues that like many other cures came from an unexpected source.

Read and comment with both interest and caution.