Unlucky 7...I'm actually surprised I haven't had this trouble until now.

[kuaka]

The more I read about possible causation factors, the more I am amazed that it took until now for me to develop this condition (it isn't really what I would consider a "disease" although it certainly cause a lack of "ease").

Chondroitin/Glucosamine got me out of a wheel chair 20 years ago...yep, 20. Been using it ever since, although only once in a while for the last seven+ years.  I've increased my use in the last year due to knee issues, but I think I missed the cause until recently.  Apparently, I'm allergic to smog.  I suffer greatly when I'm in any city which has a significant level.  It causes inflammation in my joints, starting with my knees.  Most of the time, a Benadryl stops it...and me, unless I also take a Sudafed.  Oddly enough, depending on what is actually causing my knee pain, a pipe of natural tobacco relieves it for hours, but I resist it as I am not a smoker and find the taste offensive...even of the all natural Indian tobacco I have found.  Of course tobacco use is conta-indicated while treating Peyronies Disease due to oxygen depletion.

Speaking of oxygen depletion, I had a major car accident three decades plus ago which left me with rigid ribs and scar tissue in one lung, so I have a tendency to NOT breath deeply.  Shallow breathing of course contributes to low oxygen.

My blood pressure has been marginal for years, and high enough recently to be using Lisinopril (ACE Inhibitor) to keep it down.  It generally is a direct indicator of my overall pain level, as if I'm not hurting, it stays under the "need medication" level.  High BP runs in my family.

Diabetes runs in my family too, and I do have blood sugar issues, although I manage it with diet.  I am the only one in my immediate family who is NOT a full blown insulin using adult onset type II diabetic.  I also found that Coffee (Chromium...naturally occuring) and cinnamon together are anti-diabetic.  I've been a heavy coffee drinker for years, and I like cinnamon in my coffee.  Tried cutting back last year and my blood sugar destabilized, so I'm back to drinking lots of cinnamon flavored coffee.

I was injured severely just over three decades ago.  I have a discernible scar around the girth of my penis about 1/2 to 3/4 inch below the head...and have had it for decades.  I have always been suspicious that my frequent manipulation of that tissue was preventing it from becoming more rigid, and this may ultimately the main "source" of my Peyronies Disease...the scar itself and the fact that I quit manipulating it (SA recovery, below).  

The scale used to measure T levels by my Dr. must differ from the one used in other posts here, as 600-1200 is "normal" for a man my age on the scale my Dr. uses.  Perhaps it is a total T as opposed to free T measure.  On that scale, my measure was 300-ish or about half of the low end of the "range".  I was prescribed Androgel, but can't afford to use it all the time, besides it not being that effective relying on transdermal absorption.  Recently (this week) I switched to injectable DEPO Testosterone...monthly time released injections.  I already feel different, but we'll just have to see if it helps with Peyronies Disease as well.  It is much less expensive, so I will be able to actually continue it.

I am also recently recovered from a lifelong sex addiction (SA) (from childhood, literally), and only about a year and a half ago quit heavy masturbation, which initially appears to have been preventing the onset of Peyronies Disease.  The use of porn to aid me in my use of orgasm as pain management resulted in porn induced erectile dysfunction a couple of years ago, as the pain of old injuries escalated my pain to the point of requiring MORE pain relief.  I would get enough of an erection often enough to know that Peyronies Disease was NOT an issue until this last year.  I even acknowledged that my "reboot" from SA may not be so easy, as I needed to continue manipulation to prevent the spread or hardening of the aforementioned scar tissue...which unfortunately, I did not do.  At the time, I was most interested in a successful "reboot".  I was actually almost totally surprised to find Peyronies Disease once I attempted to resume sexual activity with my wife of 25 years after the "reboot" associated with my SA recovery.  I didn't even know what Peyronies Disease was at the time.  It is only through the start of an actual pain management regimen that I was able to "reboot" from SA.  Morning wood returned after about 6 months, then in another couple of months the Peyronies Disease started to manifest.

So, I have at least 7 major potential contributing factors to the development of Peyronies Disease in my life.  I wish it were talked of more so that I could have mitigated some of these factors earlier.

[wonderbread1662]

 Wow you have been through alot man. I can relate to the smog alot. When ever I'm in LA I also have sore joints as well. Just reading this reminded me of these symptoms and I never put it together until now. Every time I had the soreness it has been in a smoggy area.  An interesting read and I found it helpful. Thanks for sharing kuaka.

[james1947]

Kuaka

Have you taught to relocate to a Pacific island? No smog there. Have done it almost 3 years ago.
Sitting in a bar on the beech, drinking a cold beer, watching the girls walking around...Peyronies or not, have better than that?
I don't know how old you are, but the health problems you are passed true are enough for more than one full life
I have also some health problems, but far from that. We say in Romanian: "To be old is a very bad disease"
Regarding testosterone, the general testosterone low level may be a culprit to Peyronies. Not in my case, as I have 698 and for may age (67), 674 is the top.
The maximum at age of 30 supposed to be 1070, minimum 270.
From this age, 1% less will be for every additional year.
You want to be close as possible to the top, not to the bottom.

James

[kuaka]

I'll be 53 this year.  I actually live where the air is pretty clean...rural Kansas.  I work in cities when I need to work.  I do computer stuff, and remote when possible...but a lot of clients just want the "touchy feelie" warm body presence.  Sad for the 21st century.  I'm somewhat semi-retired...and only work a few months out of the year.  My daughter is having some serious health issues lately and I'm working to pay her medical needs as well as trying to expand my off grid setup so I can quit working off the farm altogether.  

My right testicle was knocked out of commission when I was 19 when the "big one" happened.  My knees were wiped out when I was 18, but the rest of my issues are directly or peripherally related to that one incident.  Lost my spleen, ruptured my bladder, broke my pelvis in three places, right collar bone, four ribs, pushed my liver on the wrong side of the diaphragm, contusion of the brain (frontal lobe), so yeah, it is nothing short of a miracle that I'm even alive, let alone mostly functional.