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Author Topic: PRP & HYALURONIC ACID  (Read 27382 times)

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james1947

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Re: Dr VIRAG PRP & Hyaluronic acid treatment
« Reply #100 on: February 23, 2016, 06:10:07 PM »

I hope that this treatment will not go on the "regular" PRP way :(

James
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lespleen

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Re: Dr VIRAG PRP & Hyaluronic acid treatment
« Reply #101 on: February 23, 2016, 10:05:03 PM »

Thanks, Dros. This is purely speculative but is there any fact of the matter about how PRP + HYALURONIC ACID will act in a patient taking a variation of the PAV  cocktail ? I know that  injecting  anti-inflammatory agents to specific joint sites cannot be carried out in patients taking anticoagulants. The patient has to stop taking the anticoagulant ( including low dose asprin!) 8 days before the shot is administered to the knee, wrist, elbow, affected site in order for the injection to prove effective. Manual manipulation via traction aside, perhaps the variation on the PAV cocktail you're on is interfering with the ability of the PRP + HYALURONIC ACID  to deliver its payload and anchor itself in palce? Perhaps  the PAV cocktail, however beneficial it might be in itself, is somehow "diluting" the action of the PRP + HYALURONIC ACID? Have you discussed this possibility with Virag?
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Dros

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Re: Dr VIRAG PRP & Hyaluronic acid treatment
« Reply #102 on: March 04, 2016, 03:43:44 AM »

I did not talk to him about Pentox directly, but he knows from the survey that I take Pentox, so I guess he doesn't feel like it's a problem...

Anyway, it's two weeks after my 4th session and there are still no results when it comes to curvature... I guess it's either Xiaflex or surgery now... Unfortunately, Xiaflex is not covered by insurance in Switzerland, so I might well do it with Dr. Virag, as the way he uses echography to make sure where to inject seems actually perfect for Xiaflex, as there is almost no palpable fibrosis in my dick and the right injection site would be hard to find without echography.
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yyy

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Re: Dr VIRAG PRP & Hyaluronic acid treatment
« Reply #103 on: March 04, 2016, 03:39:47 PM »

Also dr Kuehhas in London performs Xiaflex shots together with an ultrasound
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james1947

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Re: Dr VIRAG PRP & Hyaluronic acid treatment
« Reply #104 on: June 08, 2016, 08:24:08 PM »

No news's from people treated by Dr, Virag?
So good that just not logging in anymore?

James
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Dros

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Re: Dr VIRAG PRP & Hyaluronic acid treatment
« Reply #105 on: June 09, 2016, 07:28:43 AM »

Well, in my case it was, unfortunately, a waste of time, money, and energy...  :-\
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james1947

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Re: Dr VIRAG PRP & Hyaluronic acid treatment
« Reply #106 on: June 10, 2016, 08:18:41 AM »

Thank you for the answer Dros

Like me, sadly, with the PRP :(

James
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lespleen

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Re: Dr VIRAG PRP & Hyaluronic acid treatment
« Reply #107 on: September 20, 2016, 02:48:20 AM »

It is worth noting that dr. Virag uses the Regenlab product in his published studies. I spoke with their new Regenlab USA headquarters and they confirmed that Virag uses their system. Whether or not Virag was using this system when you received your injection is another story. The Regenlab product produces one of the lowest concentrations of PRP out there and indeed they actively compare their  product with competing products on the basis of this criterion.  This might not have worked to your benefit.
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fredukas

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Re: Dr VIRAG PRP & Hyaluronic acid treatment
« Reply #108 on: September 26, 2016, 03:44:00 AM »

I met Dr Virag and Sussman last Friday for a first clinical assessment. Their clinic is located about a block from le Palais de l'Ellysée which made it easy to find. After the first exam with Dr Sussman to locate and size my plaque with an echography, they also deicded to induce an erection to take photos. My deviation is about 50 degrees to the left and upwards. I must say that I have had Peyronie's since Sep 2015 and have been treated with injectable corticosteroids for six months that have offered nothing in terms of improvement. My urologist wanted to try another round of injections before surgery that I simply refused. I also explained to my urologist about the PRP treatment and was amazed that he simply hadn't a clue. In any case, and as I am health care professional, I discussed at length with Dr Virag of the treatment that I will start next month.  I also mentioned that I had looked into going to London or even the USA and brought to his attention the notorious P shot that he labeled as a scam that doesn't work. His name has also been associated with the father of the P shot concept that he resents greatly. He then allowed me to see his research project that he will present at a conference in Venice next week. basically he has more than 150 subjects enrolled in his research project but will present 75 of them that he has followed for the last four years. I saw the stats and he was very straightforward and honest with me. The results of his study show that only one case was entirely cured but that 85% of the group showed major improvement with an average reduction in angle of 27%, firmer and better erections. He did mention that the only way to work this issue is to inject into the plaque and to follow the 4 plus two injections as per protocol. Most of his patients return once a year to get an annual maintenance treatment. His stats also showed that 85% of his patient were satisfied with the treatment but he did tell me that I would not recover my penis like it was before. I want to share this with the folks on the forum so they can realize that all of those paying big bucks for a P shot are wasting their time as it is a money making gimmick. We also discussed the use of VD or an extender and he is quite favorable but told me to hold off until we do a few treatments. I am not sure how well I will improve but will keep the forum informed of my progress over the weeks and months. My hopes and expectations are to be in the 85% group who showed significant improvement and to maybe try to use an extender after to augment my chances of a full recovery. Again, just want all to know that Virag and Sussman are REAL health specialists who care about their patients not the $ making schemes that are growing in popularity.
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lespleen

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Re: Dr VIRAG PRP & Hyaluronic acid treatment
« Reply #109 on: September 26, 2016, 04:22:46 PM »

Virag selectively injects prp into penis by targeting the plaques or plaque involved. The so called P shots involve 6 injections of PRP with three on each side. Virag is using a kit namely the Regenlab kit which produces one of the lowest concentrations of PRP out there. The P shot administered in the USA varies  in the degree of platelet concentration according to the proprietary system or systems used by the physician. The P shot isn't one unitary thing. It might not be effective in treating peyronnies because it isn't administered so as to target the plaque specifically. But it might neverthless prove effective in improving ED for the same reason Virag has met with some favorable results with Peyronies Disease despite using an inferior PRP processing system.
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Gabriel

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Re: Dr VIRAG PRP & Hyaluronic acid treatment
« Reply #110 on: April 28, 2018, 11:12:46 AM »

Hi guys !

A little up on this topic: has anyone experienced Dr Virag's injection since Dros' attempt ?

After 7 months with all the oral package + topical mixtures + traction/VED and no sign of progress, I myself took an appointment with Dr Virag for the last week of may.

Although I have well understood that I should keep low expectations about his method, I will keep you informed if I see any progress or learn something new :-)
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Tsanchez12369

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Re: Dr VIRAG PRP & Hyaluronic acid treatment
« Reply #111 on: April 28, 2018, 12:07:28 PM »

Have you tried xiaflex, or is it considerably more expensive?  Unlike PRP it shows success.
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Gabriel

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Re: Dr VIRAG PRP & Hyaluronic acid treatment
« Reply #112 on: April 28, 2018, 12:25:52 PM »

Well, actually my two urologists seem to be convinced that I should save Xiaflex as a "ultimate solution" when I enter the chronic stage (after 7 months I'm still inflammatory  :()... I think first of all I'll have Virag and Susskin examine my penis with erect echodoppler (something I never did), and see what they tell me !
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Gabriel

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Re: PRP & HYALURONIC ACID
« Reply #113 on: June 19, 2018, 12:59:19 PM »

Hi guys,

Just had my first injection of PRP + HA from Dr Virag & Sussman (still very kind, listening, patient and professional).

As I am stupid as f**k, I had not understood that I needed to spread the anaesthetic cream 30 min after arriving at the office... So the injections hurted VERY BADLY (like 8/10 on an arbitrary scale).

Now (3 hours later), my junk looks like a mutant eggplant with especially a HUGE ugly swelling on the left side. And some pain is still there... According to the dr, it should subside tonight... Let's hope so, cause it's quite painful and visually almost terrorizing.

On the bright side, the Drs told me that:
1) They don't use Regenlabs' PRP system anymore (but they couldn't tell me the exact name of their provider, as they use a French intermediary) ;
2) I may feel some quick progress about the pain (I'm still in the very acute phase), like from now until 30-45 days ;
3) I may see an improvement on the deformation in 2-4 months.

On the dark side, I've been told that:
1) I should not have sex from now until one week;
2) I should not use VED nor traction from now until 15 days;
3) I had to pay 550 euros, of which 350 euros not refunded by the insurance;
4) All of this could be pretty much useless, and Xiapex should not be an alternative as it has recently been shown to destroy almost much than to repair the penile tissues. According to Virag, all the recent studies shade the initial success of collagenase; him and Sussman even personnaly had a patient who almost lost his glans from necrosis after Xiapex; and thus they don't even offer Xiapex injections anymore unless the patient insists A LOT for it... And we're talking about doctors who practice injections at 4 hands with a live ultrasound, so I must say they are quite convincing. But I'm curious to hear about your opinions guys, as I believe to have read some pretty good Xiapex success-stories here.

So... next injections in late july, late august, and maybe late september if the situation seems to improve from this treatment. I'll keep you up to date; don't hesitate if you have questions!

Cheers,

Gabriel

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tiagofil

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Re: PRP & HYALURONIC ACID
« Reply #114 on: June 19, 2018, 05:19:09 PM »

Can people link me to the "recent studies" about CCH? We already know about potential side effects as it got a pretty rigorous clinical trial, and they're all described including penile ruptures. It was also tested against placebo injections and the people who participated couldn't do any other tratments besides hand modelling.

I would like to read the study about PRP/HA and how rigorous it was, if it was done vs. placebo and if the people who done it were properly controled about other treatments, etc.
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hope794

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Re: PRP & HYALURONIC ACID
« Reply #115 on: June 19, 2018, 05:38:06 PM »

Well said, tiagofil. I'm interested too.
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Gabriel

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Re: PRP & HYALURONIC ACID
« Reply #116 on: June 19, 2018, 06:24:49 PM »

Hello guys,

About PRP/HA, I think the only study is Virag's, and I does not seem perfectly rigorous; you'll find it there, in English: Evaluation of the benefit of using a combination of autologous platelet rich-plasma and hyaluronic acid for the treatment of Peyronie’s disease

And I guess CCH is Xiapex (Clostridium Collagenase ?...) ?
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pey ron

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Re: PRP & HYALURONIC ACID
« Reply #117 on: June 19, 2018, 07:39:44 PM »

@Gabriel, don't disappear, stp! keep us posted!

best of luck!
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Gabriel

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Re: PRP & HYALURONIC ACID
« Reply #118 on: June 20, 2018, 04:12:56 AM »

Haha don't worry Pey Ron, I do intend to stay around, cured or not... We're on the same boat, I'm not living it!

As for the sequels, on day 2 the swelling subsided a little, but 60% of my skin looks like a bloody rainbow (we've got red, pink, purple...)! Anyways, the doc said that the first effect I might experience (pain reduction) won't appear until a few days / weeks (/months)... I'll keep you updated, thanks for your support guys!
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tiagofil

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Re: PRP & HYALURONIC ACID
« Reply #119 on: June 20, 2018, 05:13:43 PM »

Great to read that there are doctors experimenting and documenting treatments (I'm going to read this paper), since this disease seems orphan from real scientific biomedical research. Good luck with the treatment. It seems all available treatments are secondary to other conditions. Traction was for micropenis, Xiaflex first for Dupuytren, etc.

CCH is indeed short for Collagenase clostridium histolyticum (xiaflex). Because it has slightly different brand names in Europe and North America I'm starting to use it more often.
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Gabriel

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Re: PRP & HYALURONIC ACID
« Reply #120 on: July 05, 2018, 03:35:16 AM »

Hi folks,

So, it's been two weeks since my first PRP + HA injection: as stated by Virag, I can't report any progress regarding hourglassing/bottlenecking/curvature/plaque reduction. Unfortunately, I can't report any progress either about pain during erections, which could have (or not) already subsided according to the doc. It doesn't seem to have worsened, though; maybe a good sign, but it's way too early to judge.

Next round of injections at the end of the month; you can count on me to keep you up to date if I experience the slightest improvement :-)!

Stay strong guys,

G
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ghost264

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Re: PRP & HYALURONIC ACID
« Reply #121 on: July 05, 2018, 11:04:58 AM »

Thanks for update @Gabriel, hopefully you will see improvement.
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Gabriel

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Re: PRP & HYALURONIC ACID
« Reply #122 on: July 24, 2018, 03:49:34 AM »

Hello guys!

I had my second round of PRP + HA, done by Dr Virag & Sussmann 6 days ago (actually by Dr Sussman and her new assistant, as Dr Virag was on holydays; but the two ladies did the thing with much competence, and this time I barely felt any pain).

I was unsure about this and I still am, but at the same time I am too excited not to share it: for the first time in 10 months, my pain in erection has subsided a little!!

Actually, the first night after the shot, I had big, long-lasting and not-so-painful erections throughout the night, which was surprising to me, as after the first round of injections my penis was in so much pain that it did not get hard for like 2-3 days. Then, through the following nights (I did not get boners during the days, as I did not see any girlfriend nor had sexual stimulation), the erections subsided a little (albeit they are still there), as did the pain, which now seems stabilized. I'd say I went from a 7/10 to a 4/10 pain in erection, which is already awesome for me.

I hope SO MUCH that this is no fluke or illusion, and that the pain won't come back with a vengeance... Nothing to report about the difformity yet, but it's said to be normal after only 2 shots (I'm aware some did not see improvement even after 6 shots).

Anyway, I'll keep you updated of course!

Bye :-),

G
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james1947

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Re: PRP & HYALURONIC ACID
« Reply #123 on: July 24, 2018, 04:04:16 AM »

Gabriel

Is he injecting in the plaque?
How many injections at one session?
Do you know the % PRP and HA and quantity?

I had PRP with no results, but if you will have results I may give it a try :)

James
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Gabriel

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Re: PRP & HYALURONIC ACID
« Reply #124 on: July 24, 2018, 04:41:14 AM »

Hi James!

Yes, they are injecting very, very precisely in the plaque, with live ultrasound (it's a 4-handed process). You get 4 injections in one session; I forgot how many mL, but it's quite a lot in total.

I never asked for the % of PRP and HA, but I know the quantity of PRP depends on the proportion of red cells you have in your own blood (for me they are quite numerous, so I "only" got 14 mL of PRP, which they told me was far enough).

Anyway, of course it's way too early to claim any result :-)... But we'll see, and I'll keep you up to date if things continue/stop changing!!!
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james1947

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Re: PRP & HYALURONIC ACID
« Reply #125 on: July 24, 2018, 10:36:46 PM »

Thanks for the answer Gabriel :)

Can I know what is your platelets count? PRP stays for "Platelets Reach Plasma" so platelets quantity is important.
Mine is 1,000,000; more than double of maximum normal, so I can make the calculations according to the 14 ml you stated.
If you will have answer for the %, please let me know. I am living in the far east, not practical for me to make to fly to France.

James
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Gabriel

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Re: PRP & HYALURONIC ACID
« Reply #126 on: July 25, 2018, 02:59:17 AM »

Hey James,

You're welcome!

Unfortunately I have no idea of my platelets count, and don't think I ever had this kind of analysis... But I just took note of your question regarding the % and quantity of PRP/HA: it is now written in my "things-to-ask-to-Virag" file I carry with me everytime I go there, so I think I'll be able to give you an answer in late august ;-).

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james1947

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Re: PRP & HYALURONIC ACID
« Reply #127 on: July 27, 2018, 03:41:39 AM »

Thanks Gabriel

James
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Gabriel

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Re: PRP & HYALURONIC ACID
« Reply #128 on: July 31, 2018, 06:29:02 AM »

Hello guys,

So, it's been 2 weeks since my second injections, 1 month and a half since the first one. Here is what I can tell so far:
- Although the first one seems to have done pretty nothing, the second shot offered me a night of infinite-like erections and a tremendous decrease in erect pain for 12 days or so. Since 2-3 days pain has come back with a vengeance, but it's probably my fault, as I had a huge consumption of alcohol and marijuana this weekend, eating BS food for 3 days instead of my super healthy diet, and pain came back right on sunday evening... Hope it won't last... Anyway, I can say for sure the second shots greatly relieved my pain at least for a while, as this reduction happened literaly overnight after the second round.

- My left curve, which was progressing at high speed since may, has clearly stopped developing, and even subsided a little (it seems I went from ~25° to ~15°). I don't know if this is imputable to PRP, but it was concomitant.

- My hourglass, unfortunately, did not stop progressing, and even worsened a little. Since it all began 10 months ago, I've lost 1cm in diameter on the top half of the shaft, 1,5cm in length, and probably 25-30% in girth. I'd say the fact that it continue to worsen recently is not due to the PRP itself, but rather to the fact that I can't do traction or VED for 15 days after each shot... Which, as you can imagine, is hell of a dilemma. Anyway, I try to focus on the good sides, and I'm telling myself that I'm getting the Restorex if it's EU approved in january, and that it will get me some length/girth back along with the VED.........

Don't hesitate if you have questions!!

Best regards folks,

G

-
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Gabriel

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Re: PRP & HYALURONIC ACID
« Reply #129 on: August 05, 2018, 07:03:55 AM »

Hi folks,

So I've made a complete erection check this morning: the slight left curvature I had and which was developping very fast is now gone, or so (it's maye 5°). I resumed traction and VED just a few days ago, so these can have helped for sure, but they cannot be accountable of this recent great progress. Is PRP responsible? Or chance? Anyway, of course I rejoice of this news, but my main and terrifying problem remains my hourglass/bottlenecking and girth/length reduction which are not getting better at all...

I'll keep on doing traction and VED and see. BTW, I might have found something useful for pain, but it's too early to be sure so I'll tell you after a good amount of testing time.

Anyway, I'm flying abroad for vacation tomorrow for 12 days, so I won't be able to post until mid August :-).

Take care,

G
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hope794

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Re: PRP & HYALURONIC ACID
« Reply #130 on: August 05, 2018, 11:32:44 AM »

Gabriel, from 25° to 5°!!! that's really great news!!
I'm really happy for you. Which effects are you noticing on EQ?

P.S. = i think that some of the issues you still have may be corrected using the VED.
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Gabriel

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Re: PRP & HYALURONIC ACID
« Reply #131 on: August 05, 2018, 12:52:46 PM »

Hi Hope, thanks for your post!

Well yes, that's very good news, albeit the curve had not preocupated me so much (25° was tolerable, but it's true I'm better off^^)!!

About EQ I really cannot tell, apart from this first crazy erections night I related: the thing is I had had psychogenic ED before Peyronie's, and since it started I almost always took daily cialis, so... I wont be able to judge properly until I stop cialis, which I don't want to do before inflammation stops!!

And yes, hopefully VED will help me regain some girth and length, but the problem is that so far it has not even allowed me to preserve my basic dimensions... Although it's true I could have been more compliant over the last weeks or months. We'll see, and hope!!!
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