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Author Topic: Long-term multimodal therapy (verapamil associated with propolis, blueberry, E..  (Read 6580 times)

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positiveoutlook

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Long-term multimodal therapy (verapamil associated with propolis, blueberry, vitamin E and local Diclofenac) on patients with Peyronie's Disease (chronic inflammation of the tunica albuginea ). Results of a controlled study - Abstract
Published on 17 December 2013

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OBJECTIVE: To demonstrate the possible effectiveness of a long-term multimodal medical therapy in patients with Peyronie's disease (Peyronies Disease) we carried out a controlled study on 82 patients diagnosed with Peyronies Disease, whereas in the scientific literature the conservative treatment of this disease is much discussed.

METHODS: 82 Patients (mean age=53.6±10.1 years-range 23-68) diagnosed with Peyronies Disease were selected for this study. Of these 41 patients (group A) were treated for 18 months as follows: Verapamil penile injections (12 total injections for six months and subsequently every month for twelve months: total 24 injections) + Iontophoresis/daily + blueberries 160mg/daily + propolis 600mg/daily +Vit.E 600mg/daily + topical Diclofenac/daily. The other 41 patients spontaneously decided not to receive treatment for several motives and then were introduced as a control group B. All patients were controlled at follow up (6 and 18 months) and underwent the same tests (penile ultrasound, photograph documentation, pain scale etc.) as performed prior to the treatment.

RESULTS: In group A, after treatment of 6 and 18 months, the change in plaque volume consisted in volume reduction= -47.6% and -73.6% respectively, while in group B the change consisted in an increase in plaque volume= +55.7% and +118.7% respectively (p=0.000). In group A, after treatment of 6 and 18 months, improvement of curvature occurred in 76.3% and 81.5% of the cases respectively, while in group B occurred in 2.7% and 8.1% respectively (p< 0.0001).

CONCLUSION: Our results showed that a long-term multimodal medical therapy (Verapamil associated with Propolis, Blueberry, Vitamin E and local Diclofenac) is statistically effective in treating Peyronies Disease, whereas, lower therapeutic responses were obtained after 6 months treatment (medium-term treatment). Furthermore, this study strongly supports the recommendation that the best approach for treating Peyronies Disease is multimodal therapy.

Written by:
Paulis G, Cavallini G, Giorgio GD, Quattrocchi S, Brancato T, Alvaro R.   Are you the author?
Andrology Center, Regina Apostolorum Hospital, Via San Francesco, 50 - CAP 00041, Albano Laziale, Rome, Italy. paulisg@libero.it

Reference: Inflamm Allergy Drug Targets. 2013 Dec 4. Epub ahead of print.


PubMed Abstract
PMID: 24304332

UroToday.com Peyronie's Section
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Realvinni2000

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I follow this regime from one of the doctors that made the study
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james1947

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And what are the results Real?
How long time are you on this treatment?

James
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Jack1909

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As far as I know it’s jus a very mainstream combo therapy sold using a captivating name and supported by some studies who is not a complete dumb know they could mean both everything and anything. It’s basically a swindle. As almost anything coming from people like cavallini and all the cheaters and preaches of false science around him..
Stay away from anything coming from Italy. Worst country in the world when it comes to health issues.
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Realvinni2000

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Why are you so angry? :(
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Jack1909

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I’m angry cause I was born in country in which people like me keep on being wasted by all the butchers we are plenty of. People who don’t even know how many better treatment options there are out there.
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Realvinni2000

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I guess I already know who you are  :-[
the therapy may help some people so it worth a try. I don't think the foregnein countries , including the US, have better options.
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Jack1909

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It’s not coming from me anymore. I won’t have a fight as, basically, people in here already know. Keep your beliefs and good luck.
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james1947

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Realvinni

Not connected top your opinion or someone else, this forum is a "free speech forum".
Every one have the right to express what he thinks except if he violates the forum rules.
Jack expressed his opinion, he have the right to do so, same as you can express your opinion on any subject.
I know much worst places than your country regarding medical treatment, but again, is Jack right to say what he thinks
Just saying
In any case the conversation is off Topic, better we concentrate in "Long-term multimodal therapy"
So let's continue on topic and not make the Administrator or a Moderator to lock the topic

James
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