Peyronies Society Forums

Please login or register.

Login with username, password and session length
Pages: 1 ... 8 9 [10]   Go Down

Author Topic: DMSO, DMSO based Solutions and TOPICAL Treatments  (Read 197663 times)

0 Members and 1 Guest are viewing this topic.

Christopher1

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 103
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #450 on: April 14, 2017, 12:41:21 AM »

How will the castor oil improve my damaged skin? I seem to have lost a lot of natural turgor since the DMSO, sadly - a sign of aging.

I am curious why castor oil in particular.
Logged

melting

  • Solid Contributor
  • ***
  • Country: de
  • Offline Offline
  • Gender: Male
  • Posts: 154
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #451 on: April 15, 2017, 05:42:30 PM »

I burned my skin with DMSO once and it then pealed off for some days until new skin appeared. Castor oil helped me.
I can imagine it taking some time to heal. I cant imagine turgor totally gone forever.
How long ago was it christopher? Is it just getting worse or is there any improvement? If there is an infection to the skin apply some cortisone lotion/cream.

Castor oil stays rather sticky to the skin and coats the skin nicely moisturizing it. Its like a second skin so to say.
It softens the skin nicely if applied overnight or long duration. Take care with clothes as it stains them.
The parts in it can replenish the skin it seems.

[If you ever do dmso again use it mixed in at least a 70/30 ratio. It truly has great properties but will burn skin if applied in undiluted strength.
If you take the dmso and mix it with some water it will have a heat reaction(which happened unfortunately in your skin now). Applying it after diluting wont create the reaction on the skin then.
Actually mixing it in a concentration like 10% with castor oil might improve your condition driving the ingredients of the castor oil deeper.]
Logged

Christopher1

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 103
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #452 on: April 16, 2017, 12:18:03 PM »

I will give it another try.

Thank you!
Logged

melting

  • Solid Contributor
  • ***
  • Country: de
  • Offline Offline
  • Gender: Male
  • Posts: 154
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #453 on: April 16, 2017, 04:52:37 PM »

DMSO needs to be premixed with water or another aqueous solution before applying to skin.
DMSO + water creates a heat reaction. If undiluted DMSO solution is put on skin the DMSO will react with water in the skin=burn.

When DMSO is advised people often say its 99% which means the quality of it.
Use 99%-Quality DMSO and mix it with water 50/50 up to 90/10.

Also dont mix with chemcials on skin or any other harmful substance as it will carry into skin.

Logged

Christopher1

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 103
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #454 on: April 17, 2017, 02:00:47 PM »

I did not know it was an exothermic reaction.

Interesting stuff.
Logged

melting

  • Solid Contributor
  • ***
  • Country: de
  • Offline Offline
  • Gender: Male
  • Posts: 154
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #455 on: April 18, 2017, 04:47:27 AM »

DMSO is quiet an interesting substance.
It "freezes" above 0°C.
It plays with the lipid layers of the skin which are normaly not penetrable for most substances.

There is a lot of mumbo jumbo talk about it on the web but also a huge amount of detailed science.

http://www.sciencedirect.com/science/article/pii/S0006349507714601
"The simulations also reveal that at high concentrations DMSO can induce water pores into the bilayer, which may be an important mechanism for permeability enhancement of solutes."
Couple this with the exothermic reaction and you have a good "burn". As it goes so deep the "burn" is also deep and not just the upper layer. Not in a fire type burn but in this weird way of displacing.
Half of my skin was peeling off for days like a snake skin and looking old and wrinkled.
I can see how it would scare you off from using it ever again.

But yeah in concentrations below 90% coupled with some afterwards skin moisturizing nothing bad happens at all.
Daily applications(which I think are needed when targeting the scar tissue) necessitate some skin care. Aloe vera and Castor oil are my favourites.

The only solution that was even at lower DMSO% a bit stingy was when I mixed it with Iodine.
Logged

Christopher1

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 103
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #456 on: April 18, 2017, 06:41:23 PM »

Interesting.
Logged

kuaka

  • Major Contributor
  • ****
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 551
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #457 on: April 18, 2017, 10:17:58 PM »

I'm about to try something.  I have ordered some liquid bromaline.  My plan is to mix it with DMSO as a carrier.  Wrap up for 15-20 minutes...cotton wrap should be ok, no latex or other exotic materials which the DMSO will suck into me.  Follow that with a VED session.  I plan on doing this once a day for a while.  If it appears too help and not hurt, I may up it to twice.
Logged

Christopher1

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 103
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #458 on: April 19, 2017, 01:23:50 AM »

Bromelain - a pineapple protease - will digest all peptides.

I would not do it. Sounds like a disaster waiting to happen.
Logged

skunkworks

  • Global Moderator
  • ****
  • Country: au
  • Offline Offline
  • Gender: Male
  • Posts: 1189
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #459 on: April 19, 2017, 04:38:33 AM »

Didn't notice this post earlier, I hope Kuaka has not tried this yet. This does not sound like a good idea at all.

You'd be using DMSO to allow an enzyme that digests protein to penetrate into your penis. Best case it does absolutely nothing as it's a pretty big molecule. Worst case it could cause you serious harm. Natural does not mean safe.

melting

  • Solid Contributor
  • ***
  • Country: de
  • Offline Offline
  • Gender: Male
  • Posts: 154
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #460 on: April 20, 2017, 12:12:31 PM »

Bromelain is too big of a molecule.
Other then that your idea is good. Combine with some other stuff like vitaminC,vitE or magnesium.(lots of info in this thread)

Make sure to warm up the VED with a heating pad(for example). Heat gives more expansion.
Also make sure that if you have DMSO on your skin that it doesnt come in contact with plastic from the VED or similar.
Logged

kuaka

  • Major Contributor
  • ****
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 551
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #461 on: April 25, 2017, 03:15:32 PM »

I've been researching injectable Bromaline for Dupreyne's...I'll do a lot more research before trying anything.  Right now I have ZERO time to devote to ANYTHING, so NOTHING is happening on this front.
Logged

peyter

  • Voting Member
  • **
  • Country: es
  • Offline Offline
  • Gender: Male
  • Posts: 37
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #462 on: May 10, 2017, 04:52:26 AM »

Dear all,

Did a lot a of efforts to try dmso and combined components applied to my penis skin in last times.
I ve been trying since january.
Dmso + evit + iodine
Dmso 70, 80, 90 % by itself
Dmso + castor oil
Dmso + contractubex
Dmso + all mixed together...

No improvements for the time being. My curvature has been progressing till an stable state.

Thats my personal feedback. I hope it has worth for anyone.

Im going to have a xiaflex cycle to stop or improve my condition.

Best for all
Logged

james1947

  • Major Contributor
  • ****
  • Country: ro
  • Offline Offline
  • Gender: Male
  • Posts: 6144
  • Age 69. Peyronies from January 2009
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #463 on: May 11, 2017, 12:37:35 AM »

Thank you for the report peyter :)
I am not trying to convince no one that DMSO is not working.
Hope some people can learn from your experience ;)

James
Logged

pey ron

  • Voting Member
  • **
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 23
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #464 on: May 11, 2017, 05:21:48 PM »

Dmso + evit + iodine

@Peyter: what is evit???

I seem to be having good success with DMSO + iosol + PABA and ALCAR both to saturation and magnesium chloride flakes, followed by the Thacker's Formula to rinse out the red stain from the iodine. I don't remember the exact proportions, but I tried to maximize PABA and ALCAR and only later add the magnesium chloride and the iosol.
Logged

Christopher1

  • Solid Contributor
  • ***
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 103
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #465 on: May 13, 2017, 09:54:57 PM »

Probably vitamin E.
Logged

Spika

  • Voting Member
  • **
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 7
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #466 on: May 15, 2017, 12:29:13 PM »

We might be having news  soon -from a reputable source-that will lead us to the right path...

I have contacted and spoke with, the Chief Science Officer of a Canadian Bio Medical Company.

They have a product (applied on the plaque) that they have finished Phase 1 clinical trials, and they are ready to start Phase 2.
The results so far are good.. The name of this product is known to this forum.

He is  open to the idea of contacting a separate and parallel Phase 2 clinical trial from this forum's members.

He will discuss it with the board this week and he will let me know.

Please stay tune...

Just in case that I get many PM and my box gets full, my email is: spi.kal@aol.com
Logged

pey ron

  • Voting Member
  • **
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 23
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #467 on: May 15, 2017, 02:24:22 PM »

@spika: how is their product related to DMSO?

other than that, i'm definitely interested in being part of a trial
Logged

Spika

  • Voting Member
  • **
  • Country: us
  • Offline Offline
  • Gender: Male
  • Posts: 7
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #468 on: May 15, 2017, 04:41:22 PM »

@ Pey ron

Please either PM me, or email me : spi.kal@aol.com
Logged

peyter

  • Voting Member
  • **
  • Country: es
  • Offline Offline
  • Gender: Male
  • Posts: 37
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #469 on: May 16, 2017, 09:08:35 AM »

Probably vitamin E.

E vitamin oil...its nice.
Logged

peyter

  • Voting Member
  • **
  • Country: es
  • Offline Offline
  • Gender: Male
  • Posts: 37
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #470 on: May 16, 2017, 09:14:03 AM »

Thanks to all.

On my personal case today i have no improvements by applying DMSO. I hope otther can have success.
I have to say i have no damage on my pennis and all products are ok...to do trials and never give up is on my way to face this condition...nex step for me will be xiaflex. I will report about it in the main thread on this forum.

Best of lucks
Logged

JayGould

  • Voting Member
  • **
  • Country: gb
  • Offline Offline
  • Gender: Male
  • Posts: 72
Re: DMSO, DMSO based Solutions and TOPICAL Treatments
« Reply #471 on: June 18, 2017, 11:57:09 AM »

Anyone tried hydrocortisone cream? Any possible negative side effects?
Logged
Pages: 1 ... 8 9 [10]   Go Up
 

Related Topics

  Subject / Started by Replies Last post
1 Replies
924 Views
Last post September 11, 2015, 10:40:38 PM
by Skjaldborg
1 Replies
446 Views
Last post April 25, 2016, 01:39:21 PM
by Crooked_Stick
7 Replies
3970 Views
Last post October 25, 2016, 12:34:46 PM
by NeoV