dealing with sleep deprivation from pentox

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Thisismyusername

I have been on Pentox for about 5 or 6 weeks now.  I started with 400 mg 3x a day, and after having serious sleep deprivation I decreased the dosage to 400 mg 2x a day.  However, I have still having serious problems feeling sleep deprived.  I often sleep 11 hours a night and still feel exhausted all day.  I am a graduate student trying to get a PhD in math and the sleep deprivation is seriously affecting my studies and intelligence.  I am scared of stopping pentox because I feel like it is my only line of defense agianst peyronie's worsening, but unfortunately I haven't noticed any beneficial effects of pentox and I just don't know if I can succeed in school on this medication.  I am also taking 2000 mg L-arginine and 300 mg CoQ10 per day.  

My question is whether or not anyone else was able to successfully manage sleep deprivation from pentox.  Currently I am taking 1 pill in the morning and 1 in the evening.  I am going to change that to 1 in the morning and 1 at lunch, but I'm not optimistic that it will help.  I've also thought of trying to find a sleep medication that could counter the effects of pentox or go to a sleep center.  I have no idea if this will help.  Currently I have been taking trazodone at night (between 25 mg to 100 mg) to help me sleep through the night.  It helps prevent me from waking up feeling horribly anxious for extended periods of time at night, but I still feel exhausted all day.  I've also taken diphenhydramine 50 mg to help sleep sometimes and it works well but I still feel tired the next day.  As scared as I am about stopping pentox, I don't think I can function like this so I want to try any final ideas before giving up on pentox.  As horrible as it is for my sex life to be ruined, I don't want my career to be ruined by peyronie's as well.  Right now I have noticed no beneficial effects from pentox - I'm still in pain, and the curve is slowly worsening.  Others have said it takes months, even a year for beneficial effects of pentox to take place, and I don't think it is worth being sleep deprived for years of my life to possibly have some relatively minor improvements.  

mmmm

How long have you been on arginine and coq10? have you noticed any benefits? Im sure there's someone more knowledgeable than me that can help you with your problem regarding pentox but keep in mind that there a list of options that could eventually help!

Skjaldborg

Thisismyusername

I was on pentox for 8 months several years ago. I had both GI upset and strange dreams while on pentox, but no insomnia. A few things you might want to try:

1. If you are waking up after 8+ hours of sleep and still feel groggy, you might be waking up in the middle of your REM cycles. Try sleeping in multiples of 1.5 hours. More info here: http://psychdigest.com/a-perfect-nights-sleep/

2. Watch your caffeine intake. Pentox seems to intensify the effects of caffeine: jitters, stomach upset, etc. Limit caffeine intake to early morning hours only.

3. Exercise in the afternoon or early evening (preferably before dinner). Exercise will wear you out and help you sleep more deeply.

Having said these things, please try to stay on the pentox for at least 6 months. It takes several months for the effects to become noticeable and it does work. I had significant erectile pain and hourglass curvature before taking it and within weeks my pain was gone and the hourglassing started to diminish. I have even seen improvements since quitting the drug. Keep at it!

-Skjaldborg

Craig

Thisismyusername, I can definitely relate to what you're going through. My most important piece of advice for you would be to start exercising. This will help your sleep problems AND peyronies in multiple ways. It will wear you out and make you more tired, allowing you to fall asleep and stay asleep. It will also help with the anxiety you seem to have, which a recent poll showed 72% of men with Peyronies have, and anxiety definitely gets in the way of sleep. Those with Peyronies are also much more prone to depression and ADHD, which also really interfere with sleep, so be mindful of your symptoms to see if you're suffering from any of these.

Back to exercising, this will also strengthen your immune system, increasing your healing speed and reducing inflammation. And when you don't get enough sleep, your body gets flooded with inflammatory cytokines, exacerbating your existing Peyronies condition.

I don't think Pentox is the primary culprit in your sleeping troubles, and your grogginess is definitely due to the sleeping pills. I don't know what trazodone is, but I think diphenhydramine is really bad for you. Any type of benzodiazepine is really bad for you, and will shrink your cerebral cortex and affect cognition. If you're not getting a lot of sun, try taking melatonin to help you sleep.

Also, I would start taking vitamin D3, magnesium, high dose fish oil/omega 3s, and a multivitamin high in vitamin C, zinc, and B-vitamins, as these will all help with anxiety and sleep as well as overall health, immune system, and your Peyronies. Try to stay away from processed food and red meat as well.  

james1947

Thisismyusername

I do have insomnia problems taking Pentox (almost two years now 3*400mg daily) but much less if taking not latter than 6 PM.

James
Age 71, Peyronies from Jan 2009 following penis fracture during sex. Severe ED.
Lost 2" length and a lot of girth. Late start, still VED, Cialis & Pentox helped. Prostate surgery 2014.
Got amazing support on the forum